Social selection in cohort studies and later representation of childhood psychiatric diagnoses: The Danish National Birth Cohort

2017 ◽  
Vol 48 (2) ◽  
pp. 207-213 ◽  
Author(s):  
Kathrine Bang Madsen ◽  
Lena Hohwü ◽  
Jin Liang Zhu ◽  
Jørn Olsen ◽  
Carsten Obel
Keyword(s):  
General Population ◽  
Birth Cohort ◽  
Psychotropic Medication ◽  
Psychiatric Diagnosis ◽  
Psychiatric Diagnoses ◽  
Social Selection ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Danish National Birth Cohort ◽  
Icd 10

Aim: This study aimed to estimate the relative representation of childhood psychiatric diagnoses and use of psychotropic medication in the Danish National Birth Cohort (DNBC) compared to the general population. Methods: The general population was identified as all childbirths in Denmark during 1998–2002 ( N=344,160). Linking the DNBC ( N=91,442) and the general population to the Danish national health registries, all children were followed until they received an ICD-10 psychiatric diagnosis, had a prescription of psychotropic medication or to the end of follow-up in 2013. The prevalence ratios (PRs) with corresponding 95% confidence intervals (CI) were estimated for each psychiatric diagnosis and by sex. Age at first diagnosis presented as means were compared using the one-sample t-test. Results: In the DNBC, the selected childhood psychiatric diagnoses were underrepresented by 3% (PR=0.97, 95% CI 0.94–0.99), ranging from a 20% underrepresentation for schizophrenia (PR=0.80, 95% CI 0.59–1.09) to a 6% over-representation for anxiety disorder or obsessive-compulsive disorder (PR=1.06, 95% CI 0.97–1.17). The majority of the specific diagnoses were modestly underrepresented in the DNBC compared to the general population, while use of psychotropic medication had similar representation. Girls were generally more underrepresented than boys. Depression was on average diagnosed 0.4 years earlier in the DNBC than in the general population ( p=0.023). Conclusions: These findings suggest that the social selection may influence the prevalence of diagnosed childhood psychiatric disorders in the DNBC.

Factor Structure and Measurement Invariance of the Obsessive-Compulsive Inventory – Child Version (OCI-CV) in General Population

2017 ◽  
Vol 33 (2) ◽  
pp. 97-103 ◽  
Author(s):  
Tíscar Rodríguez-Jiménez ◽  
Antonio Godoy ◽  
José A. Piqueras ◽  
Aurora Gavino ◽  
Agustín E. Martínez-González ◽  
...  
Keyword(s):  
General Population ◽  
Children And Adolescents ◽  
Factor Structure ◽  
Self Report ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Good Consistency ◽  
Order Factor ◽  
General Populations ◽  
Report Measure

Abstract. Evidence-based assessment is necessary as a first step for developing psychopathological studies and assessing the effectiveness of empirically validated treatments. There are several measures of obsessive-compulsive disorder (OCD) and/or symptomatology in children and adolescents, but all of them present some limitations. The Obsessive-Compulsive Inventory-Revised (OCI-R) by Foa and her colleagues has showed to be a good self-report measure to capture the dimensionality of OCD in adults and adolescents. The child version of the OCI (OCI-CV) was validated for clinical children and adolescents in 2010, showing excellent psychometric properties. The objective of this study was to examine the factor structure and invariance of the OCI-CV in the general population. Results showed a six-factor structure with one second-order factor, good consistency values, and invariance across region, age, and sex. The OCI-CV is an excellent inventory for assessing the dimensions of OCD symptomatology in general populations of children and adolescents. The invariance across sex and age warrants its utilization for research purposes.

Frequency of and Determinants for Psychotropic Drug Use in an Institution for the Mentally Retarded

1990 ◽  
Vol 156 (4) ◽  
pp. 525-530 ◽  
Author(s):  
Olav M. Linaker
Keyword(s):  
Drug Use ◽  
General Population ◽  
Psychotropic Drug ◽  
Small Proportion ◽  
Psychiatric Diagnosis ◽  
Anticonvulsant Drug ◽  
Mentally Retarded ◽  
Significant Trend ◽  
Disruptive Behaviour ◽  
Psychiatric Diagnoses

The frequency of psychotropic and anticonvulsant drug use in 168 institutionalised mentally retarded adults was studied. Use of neuroleptics and anticonvulsants was more frequent and use of hypnotics and antidepressants less frequent than in the general population. Neuroleptics were given to 49% of the population. Clients with no psychiatric diagnosis consumed less neuroleptics than those with such a diagnosis, and there was a non-significant trend for those with a more serious diagnosis (e.g. schizophrenia) to take a higher dosage. The degree of disruptive behaviour and the availability of a physician were related to dosage of neuroleptics. The various psychiatric diagnoses given could explain only a small proportion of the variance in dosage.

scholarly journals Adolescent cannabis use, baseline prodromal symptoms and the risk of psychosis

2018 ◽  
Vol 212 (4) ◽  
pp. 227-233 ◽  
Author(s):  
Antti Mustonen ◽  
Solja Niemelä ◽  
Tanja Nordström ◽  
Graham K. Murray ◽  
Pirjo Mäki ◽  
...  
Keyword(s):  
Substance Use ◽  
General Population ◽  
Birth Cohort ◽  
Psychotic Disorders ◽  
Temporal Order ◽  
Population Based ◽  
Cannabis Use ◽  
Prodromal Symptoms ◽  
Increased Risk ◽  
Icd 10

BackgroundThe association between cannabis use and the risk of psychosis has been studied extensively but the temporal order still remains controversial.AimsTo examine the association between cannabis use in adolescence and the risk of psychosis after adjustment for prodromal symptoms and other potential confounders.MethodThe sample (n = 6534) was composed of the prospective general population-based Northern Finland Birth Cohort of 1986. Information on prodromal symptoms of psychosis and cannabis use was collected using questionnaires at age 15–16 years. Participants were followed up for ICD-10 psychotic disorders until age 30 years using nationwide registers.ResultsThe risk of psychosis was elevated in individuals who had tried cannabis five times or more (hazard ratio, (HR) = 6.5, 95% CI 3.0–13.9). The association remained statistically significant even when adjusted for prodromal symptoms, other substance use and parental psychosis (HR = 3.0, 95% CI 1.1–8.0).ConclusionsAdolescent cannabis use is associated with increased risk of psychosis even after adjustment for baseline prodromal symptoms, parental psychosis and other substance use.Declaration of interestNone.

scholarly journals Study of psychiatric disorders among nepalese patients working abroad and their family members

2012 ◽  
Vol 6 (4) ◽  
pp. 1-6
Author(s):  
B Yengkokpam ◽  
SK Shah ◽  
GR Bhantana
Keyword(s):  
Psychiatric Disorders ◽  
Psychotic Disorders ◽  
Somatoform Disorders ◽  
Bipolar Affective Disorder ◽  
Family Members ◽  
International Classification Of Diseases ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Classification Of Diseases ◽  
Icd 10

This study was carried out among the patients working abroad and their family members, having various psychiatric disorders. 80 patients attending psychiatry OPD between the age of 15 to 65 years both male and female in the period of July 2009 to July 2010 were included. The results were tabulated as per the diagnostic criteria of International Classification of Diseases (ICD-10). Out of total 80 patients, 41 were males and 39 were females, whose husbands were working abroad. 30 cases were of depression,out of which 16 were males and 14 were females.18 cases were having anxiety disorders out of which 5 were males and 13 were females. 12 cases were suffering from psychotic disorders out of which 10 were males and 2 were females.7 cases were having dissociative disorders with 1 male and 6 females.4 cases were having somatoform disorders with 2 males and 2 females.1 male and 1 female were suffering from mania.1 male and 1 female were suffering from bipolar affective disorder. 2 males were alcohol dependent and 2 males were having obsessive compulsive disorder. 1 male was having organic psychosis. Journal of College of Medical Sciences-Nepal,2011,Vol-6,No-4, 1-6 DOI: http://dx.doi.org/10.3126/jcmsn.v6i4.6718

scholarly journals Increased Prevalence of Concomitant Psychiatric Diagnoses Among Patients Undergoing Hip Arthroscopic Surgery

2019 ◽  
Vol 7 (1) ◽  
pp. 232596711882245 ◽  
Author(s):  
Kag C. Iglinski-Benjamin ◽  
Michelle Xiao ◽  
Marc R. Safran ◽  
Geoffrey D. Abrams
Keyword(s):  
General Population ◽  
Acl Reconstruction ◽  
Arthroscopic Surgery ◽  
Psychiatric Disease ◽  
Psychiatric Diagnoses ◽  
Depression And Anxiety ◽  
Shoulder Stabilization ◽  
Icd 10 ◽  
Psychiatric Conditions ◽  
Chi Square Analysis

Background: Active patients with musculoskeletal pain are not immune to psychological or psychiatric disease. Observations suggest that patients undergoing hip arthroscopic surgery may have an increased prevalence of comorbid psychiatric conditions. Hypothesis: Patients undergoing hip arthroscopic surgery have an increased prevalence of concomitant psychiatric diagnoses compared with the general population as well as those undergoing anterior cruciate ligament (ACL) reconstruction. Study Design: Case-control study; Level of evidence, 3. Methods: A retrospective review of a medical claims database spanning from 2007 to 2016 was utilized to identify patients with a Current Procedural Terminology (CPT) code indicating that they had undergone hip arthroscopic surgery. This group was then dichotomized to those with or without an International Classification of Diseases, 9th Revision (ICD-9) and 10th Revision (ICD-10) diagnosis code indicating a psychological or psychiatric condition at any time before hip arthroscopic surgery or up to 2 years after hip arthrscopic surgery. As a control, ICD-9 and ICD-10 diagnosis codes for psychological or psychiatric conditions were determined in patients without a CPT code for hip arthroscopic surgery (general population) as well as for 2 surgical groups: those undergoing ACL reconstruction and those undergoing shoulder stabilization surgery. Prevalence was determined in all groups and compared using chi-square analysis. Results: There were 22,676,069 patients in the database, with 2428 undergoing hip arthroscopic surgery. Those undergoing hip arthroscopic surgery had a 3-fold increased prevalence of concomitant psychiatric diagnoses compared with the general population (52% vs 17%, respectively; P < .0001). There was a significant difference in the prevalence of psychiatric diagnoses in the hip arthroscopic surgery group between male and female patients (46% vs 56%, respectively; P = .0061), with depression and anxiety being the 2 most common comorbid conditions. Those undergoing hip arthroscopic surgery also had a significantly increased prevalence of concomitant psychiatric diagnoses versus those undergoing ACL reconstruction (52% vs 28%, respectively; P < .0001) as well as those undergoing shoulder stabilization surgery (52% vs 42%, respectively; P < .0001). Conclusion: Patients undergoing hip arthroscopic surgery had an increased prevalence of comorbid psychiatric conditions compared with the general population as well as those undergoing ACL reconstruction or shoulder stabilization surgery. Depression and anxiety were the most prevalent concomitant psychiatric diagnoses.

on the Differential Diagnosis of Obsessive-compulsive Symptoms in Schizophrenia: A Conceptual and Clinical Analysis

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
P. Michalopoulou ◽  
P. Oulis ◽  
G. Konstantakopoulos ◽  
L. Lykouras
Keyword(s):  
Differential Diagnosis ◽  
Conceptual Analysis ◽  
A Priori ◽  
Clinical Analysis ◽  
Repetitive Behaviours ◽  
Obsessive Compulsive ◽  
General Psychopathology ◽  
Compulsive Disorder ◽  
Icd 10 ◽  
Dsm Iv

Several shortcomings of the current psychodiagnostic manuals (DSM-IV, ICD-10) with respect to obsessive-compulsive disorder, such as the diagnostic parity of obsessions and compulsions and the deficient conceptualization of compulsions might artificially inflate the clinical prevalence of obsessive-compulsive (OC) symptoms in the course of schizophrenic disorders. Still, one cannot exclude on purely a priori grounds the possibility of a genuine coexistence of OC symptoms along with delusions in patients with schizophrenia. the aim of the present study was to provide a contrastive conceptual analysis of typical features of obsessions versus those of delusions and correlatively of compulsions versus delusionally-motivated repetitive behaviours, supplemented by four relevant vignettes as clinical tests of its adequacy. Although preliminary, the results of our conceptual and illustrative analyses suggest that General Psychopathology can afford the conceptual resources for the accurate differential diagnosis obsession/compulsions from delusions/delusionally-motivated repetitive behaviours. in turn, this would provide a more solid clinical ground for the investigation of the epidemiology and the pathophysiology of OC symptoms in schizophrenic disorders.

Is Anorexia Nervosa an Obsessive-Compulsive Disorder?

1990 ◽  
Vol 157 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Neil L. Holden
Keyword(s):  
Anorexia Nervosa ◽  
World Health Organization ◽  
Anterior Pituitary ◽  
World Health ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Clear Cut ◽  
Icd 10 ◽  
Health Organization ◽  
Over Time

Although anorexia nervosa may vary widely in its severity and outcome, it is usually regarded as an illness in its own right, as patients do not display major changes in the form of the illness over time (Russell, 1970). It readily lends itself to being accorded clear-cut diagnostic criteria (Russell, 1977) and this is reflected in ICD–10 (World Health Organization, 1987). However, the nosological independence of anorexia nervosa has undergone vigorous assault since its classic description by William Gull (1874). For example, the psychological nature of anorexia nervosa was obscured for 30 years by Simmond's (1914) description of anterior pituitary lesions and cachexia, and Kay & Leigh's (1954) influential study of anorexia nervosa concluded with their doubts about its status as a ‘psychiatric entity’.

Bulimia comorbidity in the general population and in the clinic

1994 ◽  
Vol 24 (3) ◽  
pp. 605-611 ◽  
Author(s):  
J. A. Bushnell ◽  
J. E. Wells ◽  
J. M. McKenzie ◽  
A. R. Hornblow ◽  
M. A. Oakley-Browne ◽  
...  
Keyword(s):  
Substance Use ◽  
General Population ◽  
Psychiatric Disorder ◽  
Substance Use Disorder ◽  
Clinical Sample ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Base Rates ◽  
Specific Increase ◽  
Bulimic Women

SynopsisThis study compares rates of comorbidity of lifetime psychiatric disorder in a clinical sample of women with bulimia, with general population base rates, and with rates of comorbidity among bulimic women in the general population. Eighty-four per cent of the clinical sample of bulimic women had a lifetime affective disorder, and 44% a lifetime alcohol or drug disorder. These rates of disorder were significantly higher than the base rates in the general population. Bulimic women in the general population also had more affective and substance-use disorders than the general population base rates, but the rates of these disorders were lower than found in the clinical sample. In the general population, quite similar rates of other disorders including generalized anxiety, panic, phobia and obsessive–compulsive disorder, are found among those with bulimia, substance-use disorder and depression. Furthermore, among those with depression and substance-use disorder in the general population, rates of eating disorder are comparable. Rather than suggesting a specific relationship between bulimia and either depression or substance-use disorder, the data from this study suggest that the presence of any disorder is associated with a non-specific increase in the likelihood of other psychiatric disorder.

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