Does a comic style informed assent form improve comprehension for minors participating in clinical trials?

2020 ◽  
pp. 147775092093037
Author(s):  
Cristina Ferrer-Albero ◽  
Javier Díez-Domingo
Keyword(s):  
Clinical Trials ◽  
Original Form ◽  
Comic Strip ◽  
Comic Strips ◽  
Critical Elements ◽  
Knowledge Based ◽  
Comprehension Score ◽  
Informed Assent ◽  
Human Participants ◽  
Graphic Elements

Background Several authors have shown that children and adolescents have limited understanding of critical elements of the research studies in which they are participating. The inclusion of graphic elements is a promising approach to increase the understandability of assent forms of clinical trials. Objectives To design a new assent form in comic strip format for minors participating in clinical trials and to compare the comprehension of this new document with a traditional assent form. Methods This study included an assessment of the readability of standard informed assents, the evaluation of the comprehension of one of these documents, the development of a new (comic format) informed assent from the original document previously evaluated, and the analysis of readability and comprehension of the new informed assent. The readability of the documents was assessed using previously validated formulas, whereas comprehension analyses were performed through a questionnaire taken by two groups of 12-year-old students of secondary schools. Ethical considerations: All procedures involving human participants were in accordance with the ethical standards of the 1964 Helsinki Declaration and its later amendments. Findings Compared with the original document, the comic assent form improved the grammatical readability of the “Aims, Risks and Benefits and How to Get More Information” sections, the comprehension scores in the Aims and Procedure sections, the understanding of ideas, and the formation of macro-ideas. The benefits of the comic strip format were more noticeable among participants in the lower percentiles of the comprehension score. Conclusions Our results show that the comic assent form has high readability and comprehensibility compared with its original form, particularly in the domains of knowledge-based inferences and macro-ideas formation. The use of forms that combine text and comic strips may help the comprehension of minors participating of a clinical trial, supporting their autonomy in decision-making.

How American Newspaper Comic Strips Portray God, Angels, and Humans

2020 ◽  
pp. 398-413
Author(s):  
Leonard Greenspoon
Keyword(s):  
Twentieth Century ◽  
Popular Culture ◽  
New Testament ◽  
Religious Identity ◽  
Online Media ◽  
Comic Strip ◽  
Comic Strips ◽  
The Bible ◽  
Biblical Texts

The comic strip as a mainstay of print and more recently online media is an American invention that began its development in the last decades of the 1800s. For many decades in the mid-twentieth century, comic strips were among the most widely disseminated forms of popular culture. With their succession of panels, pictures, and pithy perspectives, comics have come to cover an array of topics, including religion. This chapter looks at how the Bible (Old and New Testament) figures in comic strips, focusing specifically on three areas: the depiction of the divine, renderings of specific biblical texts, and how comic strips can function as sites in which religious identity and controversies play out. Relevant examples are drawn from several dozen strips. Special attention is also paid to a few, like Peanuts and BC, in which biblical imagery, ideology, and idiom are characteristically portrayed in distinctive ways.

Knowledge-Based System for Managing Complex Clinical Trials

2006 ◽  
Author(s):  
R.D. Shankar ◽  
S.B. Martins ◽  
M. O'Connor ◽  
D.B. Parrish ◽  
A.K. Das
Keyword(s):  
Clinical Trials ◽  
Knowledge Based System ◽  
Knowledge Based

scholarly journals APLICAÇÃO DE UMA HISTÓRIA EM QUADRINHOS, TRINITY, NA EDUCAÇÃO EM QUÍMICA

Química Nova ◽  
2021 ◽  
Author(s):  
Guilherme Silva ◽  
Carolina Sotério ◽  
Salete Queiroz
Keyword(s):  
Chemistry Education ◽  
Science Learning ◽  
Atomic Bomb ◽  
Comic Strip ◽  
Educational Tool ◽  
Instructional Tool ◽  
Comic Strips ◽  
Chemistry Teachers ◽  
History Of

THE APPLICATION OF A COMIC STRIP, TRINITY, IN CHEMISTRY EDUCATION. Faced with obstacles encountered in lessons and the search for actions that meet current educational needs, some attention has been paid to the role of comics as instructional tool. This article focuses on the use of a comic strip, Trinity: A Graphic History of the First Atomic Bomb, to develop knowledge and promote science learning. Three case studies were extracted from the comic and implemented to a group of pre-service chemistry teachers. A questionnaire was utilized to assess their perceptions about the usefulness of comics for their learning. One hundred percent of students indicated that comics helped improve their understanding of the nature of science. On the basis of the data, comic strips may be utilized as an acceptable educational tool in science education.

scholarly journals THE EFFECT OF COMIC STRIPS AS AN ENGLISH TEACHING MEDIA TOWARD STUDENTS’ READING ABILITY IN DESCRIPTIVE TEXT

2021 ◽  
Vol 4 (3) ◽  
Author(s):  
Arino Susanto
Keyword(s):  
Null Hypothesis ◽  
Reading Ability ◽  
Alternative Hypothesis ◽  
Control Group ◽  
Comic Strip ◽  
Comic Strips ◽  
Paired Sample ◽  
Quasi Experimental ◽  
And Control ◽  
Experimental Group

This research was done due to the lack of students' reading ability in descriptive text in MTsS Yati Kamang. This research was classified as a quasi-experimental research. To experiment class the researcher choose VII.II class and VII.I is experiment class. The researcher uses test to measure students’ reading ability. Afterwards, the researcher proved that the Comic strip as a media was able to increase students' reading ability in descriptive text. Experiment class and control class there are 38 students. There were 19 students as the respondents in experimental group and 19 students as the respondents in control group. The experimental class was taught by using Comic strips as media in teaching and the control group was taught only by using Picture. The result of paired sample t-test showed that the tobtained (6,591) was higher than ttable(2,326) with the level significant 0,01. The null hypothesis was rejected and the alternative hypothesis was accepted. It means there is a significant effect of using Comic strips toward students’ reading ability in descriptive text at the seventh grade of MTsS Yati Kamang.

scholarly journals Historical Perspectives on Ethical and Regulatory Aspects of Human Participants Research: Implications for Oncology Clinical Trials in Africa

2020 ◽  
pp. 959-965 ◽  
Author(s):  
Bodour Salhia ◽  
Victoria Olaiya
Keyword(s):  
Clinical Trials ◽  
Communicable Disease ◽  
Ethics Committees ◽  
African Countries ◽  
Historical Perspectives ◽  
Oncology Clinical Trials ◽  
Human Participants ◽  
National Regulatory Agency ◽  
Care Problems ◽  
Medical Advances

Clinical trials research involving human participants has led to numerous medical advances. Historically, however, clinical trials research was the source of major concerns for the safety and welfare of the human participants taking part in these studies. The ethical principles of autonomy, beneficence, and justice came about in response to medical atrocities, and regulations were ultimately put in place to protect the rights and welfare of human participants and to maintain the public trust in the research enterprise. Today, clinical trials are one of the most heavily regulated practices in the world, and yet still not all people are provided the same oversights and protections, with improprieties disproportionately affecting poor-resource nations and vulnerable populations. As Africa approaches the post–communicable disease era, cancer is set to take the lead as the most burdensome disease, making the need for oncology clinical trials in Africa greater than ever before. Africa represents a heterogeneous market with 55 countries, most with their own National Regulatory Agency (NRA) and each with varying levels of regulatory maturity. This diversity creates a highly complex regulatory environment and causes challenges when bringing drugs to market. There is a large need for harmonization and increased collaboration between the African nations’ NRAs. In addition, many African countries need to be better equipped to handle research ethics committees and/or learn how to rely on neighboring countries with more established ethics committees. Well-run clinical trials offer solutions to national health care problems, and all people deserve equal access to their benefits.

scholarly journals How to design and set up a clinical trial part 1: the research question

2019 ◽  
Vol 12 (3) ◽  
pp. 111-116
Author(s):  
Amarpreet Atwal ◽  
Philip E Benson
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Clinical Relevance ◽  
Clinical Care ◽  
Research Question ◽  
Relevant Information ◽  
Evidence Base ◽  
Human Participants ◽  
Set Up

Data from clinical trials involving human participants are essential in establishing an evidence base about the safety and effectiveness of our treatments. This first article describes the steps involved in designing and setting up a clinical trial, from establishing the research question(s) to searching the literature. Acquiring some knowledge about how to set up a clinical trial will allow the conscientious clinician to use the most relevant information to provide the highest possible standards of clinical care for his/her patients. CPD/Clinical Relevance: Even if a clinician is not, has never been, nor is ever planning to be involved in research, he/she should understand and be able to interpret the data from clinical trials.

scholarly journals Mockery and Morality in Popular Cultural Representations of the White, Working Class

2008 ◽  
Vol 13 (6) ◽  
pp. 1-13 ◽  
Author(s):  
Jayne Raisborough ◽  
Matt Adams
Keyword(s):  
Middle Class ◽  
Working Class ◽  
Strategic Orientation ◽  
Comic Strip ◽  
Cultural Representations ◽  
Comic Strips ◽  
New Class ◽  
Class A ◽  
White Working Class ◽  
Class Distinction

We draw on ‘new’ class analysis to argue that mockery frames many cultural representations of class and move to consider how it operates within the processes of class distinction. Influenced by theories of disparagement humour, we explore how mockery creates spaces of enunciation, which serve, when inhabited by the middle class, particular articulations of distinction from the white, working class. From there we argue that these spaces, often presented as those of humour and fun, simultaneously generate for the middle class a certain distancing from those articulations. The plays of articulation and distancing, we suggest, allow a more palatable, morally sensitive form of distinction-work for the middle-class subject than can be offered by blunt expressions of disgust currently argued by some ‘new’ class theorising. We will claim that mockery offers a certain strategic orientation to class and to distinction work before finishing with a detailed reading of two Neds comic strips to illustrate what aspects of perceived white, working class lives are deemed appropriate for these functions of mockery. The Neds, are the latest comic-strip family launched by the publishers of children's comics The Beano and The Dandy, D C Thomson and Co Ltd.

scholarly journals Improving Quality and Consistency in Clinical Trials via Knowledge-Based Planning, NRG Oncology RTOG 0631

2017 ◽  
Vol 99 (2) ◽  
pp. S107-S108
Author(s):  
K.C. Younge ◽  
R. Marsh ◽  
D. Owen ◽  
H. Geng ◽  
Y. Xiao ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Knowledge Based ◽  
Knowledge Based Planning

Racing car design using knowledge aided engineering

2000 ◽  
Vol 14 (3) ◽  
pp. 235-249 ◽  
Author(s):  
LORENZO SUSCA ◽  
FERRUCCIO MANDORLI ◽  
CATERINA RIZZI ◽  
UMBERTO CUGINI
Keyword(s):  
User Interface ◽  
Computer Aided Design ◽  
Center Of Mass ◽  
Design Parameters ◽  
Graphic User Interface ◽  
Tree Model ◽  
Car Model ◽  
Knowledge Based ◽  
Design Variables ◽  
Graphic Elements

The evolution of computer aided design (CAD) systems and related technologies has promoted the development of software for the automatic configuration of mechanical systems. This occurred with the introduction of knowledge aided engineering (KAE) systems that enable computers to support the designer during the decision-making process. This paper presents a knowledge-based application that allows the designer to automatically compute and evaluate mass properties of racing cars. The system is constituted by two main components: the computing core, which determines the car model, and the graphic user interface, because of which the system may be used also by nonprogrammers. The computing core creates the model of the car based on a tree structure, which contains all car subsystems (e.g., suspension and chassis). Different part–subpart relationships define the tree model and link an object (e.g., suspension) to its components (e.g., wishbones and wheel). The definition of independent parameters (including design variables) and relationships definition allows the model to configure itself by evaluating all properties related to dimension, position, mass, etc. The graphic user interface allows the end user to interact with the car model by editing independent design parameters. It visualizes the main outputs of the model, which consist in numeric data (mass, center of mass of both the car and its subsystems) and graphic elements (car and subsystems 3D representation).

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