Lessening Chemotherapy Side Effects With Lifestyle Medicine

2012 ◽  
Vol 6 (3) ◽  
pp. 219-221
Author(s):  
Thomas L. Lenz
Keyword(s):  
Side Effects ◽  
Stress Reduction ◽  
Review Article ◽  
Newly Diagnosed ◽  
Chemotherapy Treatment ◽  
Lifestyle Medicine ◽  
Effective Treatment Modality ◽  
Chemotherapy Side Effects ◽  
Chemotherapy Agents

An estimated 1.5 million Americans were newly diagnosed with cancer in 2011. Chemotherapy medications are a common and effective treatment modality for many types of cancers. However, the side effects of many chemotherapy agents are debilitating and negatively affect the quality of life of the individuals receiving the treatment. Several options are available that can help lessen the severity of chemotherapy side effects, some of which are lifestyle medicine related. This review article provides details about lifestyle medicine strategies such as proper nutrition, physical activity, sleep, stress reduction, and hydration in the context of mitigating some of the most common side effects related to chemotherapy treatment.

scholarly journals Rehabilitation in oncology

2021 ◽  
Author(s):  
TA Kamilova ◽  
AS Golota ◽  
DA Vologzhanin ◽  
OV Shneider ◽  
SG Scherbak
Keyword(s):  
Physical Activity ◽  
Side Effects ◽  
Psychological Health ◽  
Functional Health ◽  
Rehabilitation Programs ◽  
Clinical Complications ◽  
Rehabilitative Care ◽  
Chemotherapy Side Effects ◽  
Wide Range

Current oncology and oncohematology treatment methods allow more patients to successfully survive the disease. However, afterwards, most survivors have to deal with a wide range of symptoms and side effects and need rehabilitation. Personalized rehabilitation programs for such patients employ various methods of physical medicine. Physical activity is an important component of the cancer patients' treatment and rehabilitation. It improves their functional health, specifically — physical performance, cognitive function, psychological health, and makes the quality of their lives better. Physical activity increases muscle strength, alleviates the radiation and chemotherapy side effects and relieves fatigue. Personalized exercise programs are employed to monitor patient's condition and exercise tolerance. Physical and cognitive rehabilitative interventions are performed simultaneously as part of interdisciplinary rehabilitative care, so this approach can have a synergistic effect. It is necessary to factor in contraindications when prescribing regular physical activity, exercise and other methods of rehabilitation, otherwise they can lead to clinical complications.

scholarly journals Chemotherapy-Induced Cachexia and Model-Informed Dosing to Preserve Lean Mass in Cancer Treatment

2021 ◽  
Author(s):  
Suzan Farhang-Sardroodi ◽  
Michael A. La Croix ◽  
Kathleen P. Wilkie
Keyword(s):  
Quality Of Life ◽  
Mathematical Model ◽  
Side Effects ◽  
Lean Mass ◽  
Dose Dependence ◽  
Muscle Loss ◽  
Chemotherapy Treatment ◽  
Linear Dose ◽  
Non Linear

AbstractAlthough chemotherapy is a standard treatment for cancer, it comes with significant side effects. In particular, certain agents can induce severe muscle loss, known as cachexia, worsening patient quality of life and treatment outcomes. 5-fluorouracil, an anti-cancer agent used to treat several cancers, has been shown to cause muscle loss. Experimental data indicates a non-linear dose-dependence for muscle loss in mice treated with daily or week-day schedules. We present a mathematical model of chemotherapy-induced muscle wasting that captures this non-linear dose-dependence. Area-under-the-curve metrics are proposed to quantify the treatment’s effects on lean mass and tumour control. Model simulations are used to explore alternate dosing schedules, aging effects, and morphine use in chemotherapy treatment with the aim of better protecting lean mass while actively targeting the tumour, ultimately leading to improved personalization of treatment planning and improved patient quality of life.Author SummaryIn this paper we present a novel mathematical model for muscle loss due to cancer chemotherapy treatment. Loss of muscle mass relates to increased drug toxicity and side-effects, and to decreased patient quality of life and survival rates. With our model, we examine the therapeutic efficacy of various dosing schedules with the aim of controlling a growing tumour while also preserving lean mass. Preservation of body composition, in addition to consideration of inflammation and immune interactions, the gut microbiome, and other systemic health measures, may lead to improved patient-specific treatment plans that improve patient quality of life.

Patients’ perception of chemotherapy side effects: Expectations, doctor-patient communication and impact on quality of life - An Italian survey

2016 ◽  
Vol 26 (2) ◽  
pp. e12618 ◽  
Author(s):  
Domenica Lorusso ◽  
Emilio Bria ◽  
Anna Costantini ◽  
Massimo Di Maio ◽  
Giovanni Rosti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Patient Communication ◽  
Doctor Patient Communication ◽  
Italian Survey ◽  
Chemotherapy Side Effects

scholarly journals Penerapan Auricular Acupressure Untuk Mengurangi Konstipasi Pasien Kemoterapi

JKEP ◽  
2020 ◽  
Vol 5 (2) ◽  
pp. 161-170
Author(s):  
Edianto Edianto ◽  
Agung Waluyo ◽  
Sri Yona ◽  
Yunisar Gultom
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Cancer Patients ◽  
Nursing Intervention ◽  
Chemotherapy Treatment ◽  
Post Intervention ◽  
Treatment Room ◽  
Auricular Acupressure ◽  
Significant Difference

Most cancer patients receive chemotherapy which contributes to prolong life, with the most common side effects of constipation. Constipation causes general symptoms that are bad and affect the quality of life of patients. The purpose of evidance based nursing (EBN) is to identify the effectiveness of Auricular acupressure in overcoming symptoms of constipation in cancer patients receiving chemotherapy. This EBN uses quasi experiments involving 14 participants in the chemotherapy treatment room with pre and post intervention assessments. The results of the analysis of the independent t-test showed that there was a significant difference in the form of faeces on day 6 with p <0.000 (95% CI). Conclusion: Auricular acupressure can be used as a constipation management nursing intervention in cancer patients undergoing chemotherapy.

Clinical characteristics associated with the development of anticipatory nausea and vomiting in cancer patients undergoing chemotherapy treatment.

1984 ◽  
Vol 2 (10) ◽  
pp. 1170-1176 ◽  
Author(s):  
G R Morrow
Keyword(s):  
Side Effects ◽  
Cancer Patients ◽  
Nausea And Vomiting ◽  
Cancer Center ◽  
Chemotherapy Treatment ◽  
Anticipatory Nausea ◽  
Clinical Control ◽  
Chemotherapy Side Effects ◽  
Anticipatory Nausea And Vomiting ◽  
The University

Approximately one in four patients experiences nausea and/or vomiting in anticipation of a chemotherapy treatment by the time of their fourth treatment cycle. Anticipatory nausea and vomiting is a prevalent problem of clinical significance in the total management of chemotherapy side effects. While refractory to standard antiemetic treatment, anticipatory nausea and vomiting has been successfully treated with behavioral approaches such as systemic desensitization. The present study was designed to identify the characteristics of patients at high risk for developing anticipatory side effects. Early identification of cancer patients prone to developing anticipatory side effects could lead to preventive measures. One hundred seventy-six consecutive ambulatory patients with histologically confirmed cancer who were being treated at three geographically separate hospitals of the University of Rochester Cancer Center were studied at the time of their fourth chemotherapy treatment. Patients found to experience anticipatory nausea and vomiting were significantly more likely (P less than .001) to have four or more of the following characteristics than patients who did not report anticipatory side effects: (1) less than 50 years of age; (2) the experience of nausea and/or vomiting after their last chemotherapy treatment; (3) a description of nausea after the last treatment as "moderate, severe, or intolerable"; (4) a description of vomiting after the last treatment as "moderate, severe, or intolerable"; (5) the reporting of the side effect "warm or hot all over" after their last treatment; (6) a susceptibility to motion sickness; (7) the experience of "sweating after their last treatment"; (8) and the experience of "generalized weakness after their last chemotherapy treatment." Results support a view that anticipatory side effects are conditioned and point to practical interventions for their clinical control.

scholarly journals Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer

2008 ◽  
Vol 22 (6) ◽  
pp. 969-981 ◽  
Author(s):  
Linda Witek-Janusek ◽  
Kevin Albuquerque ◽  
Karen Rambo Chroniak ◽  
Christopher Chroniak ◽  
Ramon Durazo-Arvizu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Immune Function ◽  
Stress Reduction ◽  
Early Stage ◽  
Early Stage Breast Cancer ◽  
Newly Diagnosed ◽  
Mindfulness Based Stress Reduction ◽  
And Coping

Nutritional interventions based on dietary restriction and nutrient reductions for the prevention of doxorubicin chemotherapy side effects

2021 ◽  
pp. 1-12
Author(s):  
Jose M. Romero-Márquez ◽  
Alberto Badillo-Carrasco ◽  
María D. Navarro-Hortal ◽  
Lorenzo Rivas-García ◽  
Victoria Jiménez-Trigo ◽  
...  
Keyword(s):  
Side Effects ◽  
Stress Reduction ◽  
Dietary Fat ◽  
Critical Role ◽  
Dietary Interventions ◽  
Nutritional Interventions ◽  
Beneficial Effects ◽  
Chemotherapy Side Effects ◽  
Liver And Kidney ◽  
Protein Reduction

BACKGROUND: Doxorubicin (DOX) is one of most used chemotherapeutic drugs, but it has important adverse effects. Nutrition has a critical role to prevent or minimize chemotherapy side effects. Caloric and nutrient restriction has been widely studied in different health fields showing extensive beneficial effects. Given the importance of these interventions, it is expected that some of them have benefits in patients under DOX chemotherap OBJECTIVE: This review aimed to compile published studies evaluating the effects of different dietary intetrventions based on restriction of calories or certain nutrients against DOX-induced damage and toxicity. RESULTS: Caloric restriction and partial reduction of fat have shown to reduce DOX cardiotoxicity correlating with a reduction of oxidative stress. Reduction of dietary fat was proved to act in the same sense at liver and kidney. Studies in relation to protein reduction is more elevated has focused only on kidneys and bone, and under certain circumstances, these interventions could increase susceptibility to DOX toxicity. CONCLUSIONS: The promising effects of restriction of dietary fat, protein and sodium on differerent organs have been supported by a greater number of studies among all the dietary interventions evaluated. Still, clinical studies are necessary to confirm the potential usefulness of these interventions.

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