scholarly journals Chemical Constituents from Nicotiana tabacum L. and Their Antifungal Activity

2021 ◽  
Vol 16 (11) ◽  
pp. 1934578X2110595
Author(s):  
Chen Yang ◽  
Sheng-Nan Xie ◽  
Lin Ni ◽  
Yong-Mei Du ◽  
Su Liu ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Nicotiana Tabacum ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Etoh Extract ◽  
Phytochemical Investigation ◽  
Nicotiana Tabacum L ◽  
Alternaria Porri ◽  
Antifungal Effects ◽  
Valsa Mali

A phytochemical investigation of an aqueous ethyl alcohol (EtOH) extract of the flowers of Nicotiana tabacum L . led to the identification of one new eudesmane-type sesquiterpenoid (1) and 14 known compounds, including 7 flavones (2-8), 6 phenolic acids (9-14), and 1 coumarin (15). The chemical structure of 1 was established on the basis of high-resolution electrospray ionization (HRESIMS) and 1D and 2D NMR analyses, while the other structures were elucidated by 1D NMR and LC–MS data. The antiphytopathogenic activities of all the isolated compounds were tested to determine their antifungal activity against Valsa mali var. mali, Alternaria porri, and Botrytis cinerea at a concentration of 10 µg/mL. Compound 4 exhibited more potent antifungal effects against Valsa mali var. mali with a % growth inhibition of 47.9 ± 1.2%, while the others only showed insignificant activities.

scholarly journals CONTRIBUTE TO STUDY ON CHEMICAL CONSTITUENTS OF URENA LOBATA (L.) OF VIETNAM

2019 ◽  
Vol 57 (2) ◽  
pp. 162
Author(s):  
Quan Minh Pham ◽  
Hoai Van Thi Tran ◽  
Lam Tien Do ◽  
Phuong Lan Doan ◽  
Inh Thi Cam ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Ethyl Acetate ◽  
Ethyl Acetate Extract ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Spectroscopic Methods ◽  
Tree Roots ◽  
Chemical Structures ◽  
Phytochemical Investigation ◽  
First Time

Urena lobata L. is used in Vietnamese traditional medicine for the treatment of several diseases. Tree roots are used to treat rheumatism, dysentery, poor digestion, flu, tonsils, malaria, asthma, goiter. Flowers are used to treat chickenpox, fever, and mental disorders. Branches, leaves or whole trees used to treat injuries bruises, rheumatism, mastitis, bites. Phytochemical investigation of the n-hexan and ethyl acetate extract of Urena lobata L. led to the isolation of β-sitosterol (1), β-sitosterol-3-O-β-D-glucopyranoside (2), a-acetylamino-phenylpropyl a-benzoylamino-phenylpropanoate (3), quercetin (4), and trans-tiliroside (5). Their chemical structures were determined by spectroscopic methods including MS, 1D, 2D NMR and comparing with those reported in previous papers. Two compounds 3, 5 were isolated for the first time from Urena lobata plant.

scholarly journals Chemical Constituents of the Bulbs of Scilla peruviana and Their Pancreatic Lipase Inhibitory Activity

2021 ◽  
Vol 22 (3) ◽  
pp. 1262
Author(s):  
Yukiko Matsuo ◽  
Asuka Yamashiro ◽  
Kanae Ootomo ◽  
Mika Nakagawa ◽  
Hiroko Tsuchihashi ◽  
...  
Keyword(s):  
Pancreatic Lipase ◽  
Inhibitory Activity ◽  
Chemical Constituents ◽  
Serum Triglyceride ◽  
2D Nmr ◽  
Triterpene Glycosides ◽  
Dependent Manner ◽  
Concentration Dependent Manner ◽  
Phytochemical Investigation

Scilla species are used as medicinal plants and contain lanosterol-type triterpene glycosides. The phytochemical investigation of the bulbs of Scilla peruviana led to the isolation of 17 compounds, including three new rearranged pentacyclic-lanosterol glycosides (1–3) and two new homoisoflavanone glycosides (12 and 13). The structures of the undescribed compounds were determined by extensive spectroscopic analyses, including two-dimensional (2D) NMR. Among the triterpene glycosides, 2, 3, and 6 showed significant pancreatic lipase inhibitory activity in a concentration-dependent manner in vitro. The oral administration of scillascilloside D-2 (6) reduced serum triglyceride levels in a dose-dependent manner in soybean oil-loaded mice.

scholarly journals An Update on Chemical Constituents from Nicotiana tabacum L. and Their Bioactivities from 2017 to 2020

2020 ◽  
Vol 4 (4) ◽  
pp. 200019-200019
Author(s):  
Kuo Xu ◽  
Kuo Xu ◽  
Qian Liu ◽  
Lin Ni ◽  
Yong-Mei Du and Zhong-Feng Zhang ◽  
...  
Keyword(s):  
Nicotiana Tabacum ◽  
Chemical Constituents ◽  
Nicotiana Tabacum L

scholarly journals Chemical Constituents of Cichorium intybus and their Inhibitory Effects against Urease and α-Chymotrypsin Enzymes

2011 ◽  
Vol 6 (8) ◽  
pp. 1934578X1100600
Author(s):  
Sumayya Saied ◽  
Shazia Shah ◽  
Zulfiqar Ali ◽  
Ajmal Khan ◽  
Bishnu P. Marasini ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
2D Nmr ◽  
Cichorium Intybus ◽  
Spectroscopic Techniques ◽  
Inhibitory Effects ◽  
Isolation And Identification ◽  
Aerial Parts ◽  
Phytochemical Investigation ◽  
Hydroxyphenylacetic Acid ◽  
First Time

Phytochemical investigation of the aerial parts of Cichorium intybus L. resulted in the isolation and identification of two new natural metabolites, 2,6-di[but-3( E)-en-2-onyl]naphthalene (1), and 3,3′,4,4′-tetrahydroxychalcone (2), along with nine known compounds. Their structures were determined by spectroscopic techniques including 1D and 2D NMR. The known compounds were identified as scopoletin (3), 4-hydroxyphenylacetic acid (4), 3-hydroxy-4-methoxybenzoic acid (5), 4,4′-dihydroxychalcone (6), 6,7-dihydroxycoumarine (7), 1-triacontanol (8), lupeol (9), β-sitosterol (10), and β-sitosterol-3- O-β-glucopyranoside (11). Compounds 4-6 and 8 are reported for the first time from C. intybus. Compounds 2 and 3 showed weak inhibitory activities against urease and α-chymotrypsin enzymes, respectively.

Chemical Constituents of Adesmia Boronioides and Evaluation of their Antioxidant Activity

2015 ◽  
Vol 8 (3) ◽  
pp. 2919-2223
Author(s):  
Orlando Muñoz ◽  
C Delporte
Keyword(s):  
Chemical Constituents ◽  
Antioxidant Properties ◽  
2D Nmr ◽  
Isolation And Identification ◽  
Ongoing Research ◽  
Phytochemical Investigation ◽  
Kaempferol Glycoside ◽  
Pharmacologically Active ◽  
Pharmacologically Active Compounds ◽  
First Time

As part of our ongoing research into the pharmacologically active compounds of Chilean flora, here we did phytochemical investigation of Adesmia boronioides Hook.f (fabaceae). (Papilonaceae) leaves. This effort has led to isolation and identification of liqueritigenin, isoliquiritigenin, sesamin, isodrimenin and a kaempferol glycoside, kaempferol 3-O-β-D-[galactopyranosyl  (1–2) rhamnoside]-7-O –α-L-rhamnopyranoside.Compound structures were identified by 1D- and 2D-NMR experiments, mass and UV spectrometry and comparison with data from the literature. This is the first time these compounds have been isolated from this plant’s leaves.These active constituents have been studied further pharmacologically. Antioxidant properties in A. boronioides leaves were determined.

scholarly journals Chemical Constituents from Stems of Pileostegia viburnoides

2019 ◽  
Vol 14 (1) ◽  
pp. 1934578X1901400
Author(s):  
Xiao-Jun Li ◽  
Kwan-Woo Kim ◽  
Qin-Peng Zou ◽  
Zu-Zhen Liu ◽  
Hyun-Cheol Oh ◽  
...  
Keyword(s):  
Optical Rotation ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Spatial Structures ◽  
H Nmr ◽  
Mass Data ◽  
Phytochemical Investigation ◽  
Coumarin Glycoside ◽  
First Time ◽  
Nmr Signals

Phytochemical investigation on the stems of Pileostegia viburnoides Hook.f.et Thoms led to the isolation of twelve compounds, including two steroids (1 and 10), two fatty compounds (2 and 12), seven triterpenoids (3–9), and one coumarin glycoside (11). 24-methylene-5α-dammara-20(21)-en-3β-yl acetate (5), a rare dammarane-tetracyclic triterpene had been first reported just according to the typical 1H-NMR signals analysis, melting point and optical rotation in 1975. However, the complete and reliable NMR and mass data were still unknown. This is the first time to identify the planar and spatial structures of compound 5 by the analysis of 1D-, 2D-NMR, mass data and other physicochemical properties, as well as by comparison of the spectral data with the literature. Further more, the anti-inflammatory and anti-neuroinflammatory activities of dammarane-type triterpenes 4 and 5 were evaluated.

scholarly journals Genetic Influence on Chemical Constituents of Tobacco Leaf and Smoke

1975 ◽  
Vol 8 (4) ◽  
Author(s):  
J.F. Chaplin
Keyword(s):  
Nicotiana Tabacum ◽  
Genetic Basis ◽  
Genetic Factors ◽  
Reducing Sugars ◽  
Chemical Constituents ◽  
Cultural Factors ◽  
Water Soluble ◽  
Nitrogenous Compounds ◽  
Breeding Lines ◽  
Nicotiana Tabacum L

AbstractInvestigations have shown that many chemical constituents in tobacco (Nicotiana tabacum L.) plants and in the cured leaf are influenced by genetic, environmental, and cultural factors. The genetic basis for nicotine synthesis is well documented and plant breeders are capable of developing cultivars with varying levels. Differences for chemical constituents have been detected among cultivars and breeding lines which are attributed to genetic factors. Some of these constituents are: reducing sugars, polyphenols, phytosterols, and nitrogenous compounds. Research also indicates that alkalinity of water-soluble ash and certain smoke constituents are influenced by genetic factors

scholarly journals The Phytochemical Investigation and Biological Activities of Berberis Orthobotrys

2017 ◽  
Vol 9 (2) ◽  
Author(s):  
Akber Dad ◽  
Iftikhar Ali ◽  
Nadja Engel ◽  
Muhammad Atif ◽  
Hidayat Hussain ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Fusarium Solani ◽  
Leaf Extract ◽  
Biological Activities ◽  
2D Nmr ◽  
Published Data ◽  
Root Extract ◽  
Spectroscopic Methods ◽  
Phytochemical Investigation ◽  
First Time

<p>The leaf extract of <em>Berberis orthobotrys </em>Bien. ex Aitch.<em> </em>(B.o.)<em> </em>afforded three compounds viz., β-sitosterol (<strong>1</strong>), sesamin (<strong>2</strong>) and 10-eicosanol (<strong>3</strong>) which were identified by spectroscopic methods including 1D and 2D NMR, GC-MS, IR and comparison of their spectral data with the published data. To the best of our knowledge these three compounds are reported here for the first time to be isolated from <em>Berberis orthobotrys </em>Bien. ex Aitch.<em> </em>(B.o.). Moreover the root extract exhibited good antilieshmanial activity and root and fruit extracts demonstrated minor antifungal activity against <em>Fusarium solani</em>.</p>

Chemical Constituents of Nepeta Distans

2010 ◽  
Vol 5 (11) ◽  
pp. 1934578X1000501 ◽  
Author(s):  
Javid Hussain ◽  
Nausheen Bukhari ◽  
Hidayat Hussain ◽  
Najeeb U Rehman ◽  
Syed Murtaza Hussain
Keyword(s):  
Spectral Data ◽  
Phenolic Compound ◽  
Ursolic Acid ◽  
Oleanolic Acid ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Phytochemical Investigation ◽  
Reported Data ◽  
First Time

Phytochemical investigation of Nepeta distans Raul resulted in the isolation of a new phenolic compound, nepatanol (1), and eight known compounds, markhamioside F, netidiol, nepedinol, thymoquinone, eugenol, oleanolic acid, ursolic acid, and β-sitosterol, which have been isolated for the first time from this source. Structures of all the isolates were established on the basis of MS, and 1D and 2D NMR spectral data and by comparison with reported data.

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