Selection of Treatment between GDC and Surgery for Acutely Ruptured Cerebral Aneurysms Based on Short and Long-term Clinical Results

2003 ◽  
Vol 16 (6) ◽  
pp. 1188-1190
Author(s):  
K. Fukui ◽  
O. Suzuki ◽  
S. Ito ◽  
M. Miyazaki
Keyword(s):  
Cerebral Aneurysms ◽  
Clinical Results ◽  
Short And Long Term ◽  
Selection Of

Contemporary Treatment for Central Serous Chorioretinopathy

2021 ◽  
Author(s):  
Mitova D
Keyword(s):  
Subretinal Fluid ◽  
Functional Results ◽  
Clinical Results ◽  
Long Term Results ◽  
Nanosecond Laser ◽  
Success Rates ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Short And Long Term

Aim: To study the short-and long-term results of 2RT nanosecond laser treatment for CSC. To compare clinical results with those with AntiVEGF. Methods: Nanosecond laser (2RT, Ellex) was used. Patients were followed by BCVA, FAF, OCT, Angio-OCT. Results: 90% of the patient treated with 2RT had improvement of visual acuity and contrast sensitivity. 19 % [1] patients showed no improvement. 81% of the 2RT treated patients had total resorbtion of subretinal fluid against 60% treated with AntiVEGF. Functional results correlated with the atrophy of RPE in the macula. 46% (19 patients) had resolution on the first month, 23% [2]-on the third and 12% [3]-on the sixth month. The time of resolution shows no relation to the baseline pigment epithelial atrophy. Four patients presented with a recurrency of the disease in the follow-up period. 19% [1] were non responders. 60% of AntiVEGF treated eyes were responders and 40% were non responders. Those who responded to treatment needed between 3 and 10 injections. Conclusion: 2 RT is a non-invasive treatment modality with no adverse effects and high success rates.

scholarly journals Hypertension in pregnancy: a review of therapeutic options

2012 ◽  
Vol 5 (2) ◽  
pp. 44-49 ◽  
Author(s):  
D Kernaghan ◽  
A C Duncan ◽  
G A McKay
Keyword(s):  
Therapeutic Options ◽  
National Guidelines ◽  
Hypertension In Pregnancy ◽  
Maternal Morbidity And Mortality ◽  
Hypertensive Disorders In Pregnancy ◽  
Short And Long Term ◽  
Maternal And Neonatal Outcomes ◽  
Selection Of ◽  
In Pregnancy

Hypertensive disorders in pregnancy are common and can occur as a result of pre-existing hypertension or as new onset hypertension usually in the second half of pregnancy. In either situation there is potential for considerable perinatal and maternal morbidity and mortality. This review article aims to compare therapeutic options outlined in a selection of national guidelines and to look in more detail at the most commonly prescribed drugs – labetalol, methyldopa and nifedipine – with respect to their pharmacology and the evidence for their use in pregnancy. We will also consider the rationale for identifying and treating hypertension in pregnancy and the effect this can have on short- and long-term maternal and neonatal outcomes.

Development and Implementation of a Risk Based Prioritization Methodology for MAOP Reconfirmation of Gas Transmission Facilities

2016 ◽  
Author(s):  
Wytze Sloterdijk ◽  
Martin Hommes ◽  
Roelof Coster ◽  
Troy Rovella ◽  
Sarah Herbison
Keyword(s):  
Oil And Gas ◽  
Environmental Data ◽  
Operating Pressure ◽  
Line Pipe ◽  
Relative Significance ◽  
Coherent Risk ◽  
Relative Risks ◽  
Short And Long Term ◽  
Selection Of

As part of Pacific Gas and Electric Company’s (PG&E) on-going commitment to public safety, the company has begun a comprehensive engineering validation of its gas transmission facilities that will ultimately support the reconfirmation of maximum allowable operating pressure (MAOP) for these assets. In addition to 6,750 miles of line pipe, PG&E’s gas transmission system contains over 500 station facilities. Since this set of facilities is not only large but diverse, and the validation effort for these facilities is expected to be an extensive, multi-year process, a methodology for the prioritization of the facilities needed to be developed to facilitate planning of the process for the efficient mitigation of risk. As a result, DNV GL was retained to develop and implement a risk-based prioritization methodology to prioritize PG&E’s gas transmission facilities for the engineering validation and MAOP reconfirmation effort. Ultimately, a weighted multiple criteria decision analysis (MCDA) approach was selected and implemented to generate the prioritization. This MCDA approach consisted of the selection of relevant criteria (threats) and the weighting of these criteria according to their relative significance to PG&E’s facilities. Relevant criteria selected for inclusion in the analysis include factors that are important in order to assess both the short- and long-term integrity of the facility as a whole as well as the integrity of features for which design records cannot be located. The criteria selected encompass stable threats, time-dependent threats, as well as environmental impact. Enormous amounts of data related to design, operations, maintenance history and meteorological and seismic activity in addition to other environmental data were evaluated with this newly developed methodology to assess the relative risks of the facilities. Pilot field visits were performed to validate the selection of the various criteria and to confirm the outcome of the analysis. The novelty of this approach lies in the prioritization of facilities in a coherent risk-based manner. The described approach can be used by operators of oil and gas facilities, either upstream, midstream or downstream.

Modeling Approach to Determine Short- and Long-Term Thermal and Thermomechanical Effects of Waste Emplacement in a Repository in Basalt

1981 ◽  
Vol 11 ◽  
Author(s):  
Terry F. Lehnhoff ◽  
K. Thirumalai ◽  
Alan D. Krug
Keyword(s):  
Pacific Northwest ◽  
United States Of America ◽  
The United States ◽  
Department Of Energy ◽  
Nuclear Waste Repository ◽  
Columbia River Basalts ◽  
The Pacific ◽  
Short And Long Term ◽  
Selection Of

The Columbia River basalts, which underlie a large portion of the Pacific Northwest of the United States of America, are being investigated as one of the candidate media for a nuclear waste repository. The Basalt Waste Isolation Project (BWIP) of Rockwell Hanford Operations (Rockwell) is conducting these investigations for the U.S. Department of Energy (DOE). Since the inception of the program in 1976, a number of studies have led to the selection of a reference repository location and the start of construction of an exploratory shaft.1-3

SELECTION OF SUPPLIERS CONSIDERING THE LEARNING EFFECT AND TECHNOLOGY IMPROVEMENT

2003 ◽  
Vol 02 (01) ◽  
pp. 71-92 ◽  
Author(s):  
WANZHEN HUANG ◽  
SHANLING LI ◽  
DEVANATH TIRUPATI
Keyword(s):  
Learning Effect ◽  
Cost Models ◽  
Learning Effects ◽  
Market Prices ◽  
Trade Offs ◽  
Technology Improvement ◽  
Short And Long Term ◽  
Supplier Contracts ◽  
Selection Of

In this paper, we develop a model-based approach to examine the trade-offs between short- and long-term supplier contracts. Specifically, we consider learning and technology breakthroughs leading to cost improvements and develop cost models to characterize these effects. A deterministic environment is first considered in which demand can be constant or dynamic and learning effects and technology breakthroughs are dynamic. Then uncertainty in market prices is considered. Interesting managerial insights and strategies in selecting suppliers are discussed based on the analytical results of the models.

Retrospective analysis of intracranial aneurysms after flow diverter treatment including color-coded imaging (syngo iFlow) as a predictor of aneurysm occlusion

2021 ◽  
pp. 159101992110240
Author(s):  
Andreas Simgen ◽  
Christine Mayer ◽  
Michael Kettner ◽  
Ruben Mühl-Benninghaus ◽  
Wolfgang Reith ◽  
...  
Keyword(s):  
Cerebral Aneurysms ◽  
Flow Diverter ◽  
Complication Rates ◽  
Long Term Follow Up ◽  
Aneurysm Growth ◽  
Short And Long Term ◽  
Aneurysm Occlusion ◽  
Unruptured Cerebral Aneurysms

Purpose Flow Diverters (FD) have immensely extended the treatment of cerebral aneurysms in the past years. Complete aneurysm occlusion is a process that often takes a certain amount of time and is usually difficult to predict. Our aim was to investigate different syngo iFlow parameters in order to predict aneurysm occlusion. Methods Between 2014 and 2018 patients with unruptured cerebral aneurysms treated with a FD were reviewed. Aneurysm occlusion and complication rates have been assessed. In addition, various quantitative criteria were assessed using syngo iFlow before, after the intervention, and after short and long-term digital subtraction angiography (DSA). Results A total of 66 patients hosting 66 cerebral aneurysms were included in this study. 87.9% (n = 58) aneurysms in the anterior and 12.1% (n = 8) in the posterior circulation were treated. Adequate aneurysm occlusion at long-term follow-up (19.05 ± 15.1 months) was achieved in 90.9% (n = 60). Adequately occluded aneurysm revealed a significantly greater peak intensity delay (PI-D, p = 0.008) and intensity decrease ratio (ID-R, p < 0.001) compared to insufficiently occluded aneurysms. Increased intra-aneurysmal contrast agent intensity (>100%) after FD implantation resulted in an ID-R < 1, which was associated with aneurysm growth during follow-up DSA. Retreatment with another FD due to foreshortening and/or aneurysm growth was performed in 10.6% (n = 7). Overall morbidity and mortality rates were 1.5% (n = 1) and 0%. Conclusion The applied syngo iFlow parameters were found to be useful in predicting adequate aneurysm occlusion and foresee aneurysm growth, which might indicate the implantation of another FD.

scholarly journals An Analysis of Research on Constructivist Teacher Education

in education ◽  
2013 ◽  
Vol 17 (2) ◽  
Author(s):  
Julie Rainer Dangel
Keyword(s):  
Teacher Education ◽  
Preservice Teachers ◽  
Program Development ◽  
Classroom Practice ◽  
Future Research ◽  
Policy And Practice ◽  
Short And Long Term ◽  
Practice Development ◽  
Selection Of

This review of research (1990 to 2009) on constructivist teacher education synthesizes a growing but fragmented body of research and links it to practice in teacher education; it provides a guide for future research, program development, and policy and practice development which is consistent with empirical evidence.  It includes a selection of 27 studies on preservice efforts; efforts which include programs, courses, and field experiences.  First, an analysis of the research suggests a variety of effects from both short- and long-term experiences.  Effects are identified in two categories: (a) conceptual understandings (with three subcategories: understanding of content, pedagogy, and the self as learner) and (b) classroom practice.  Then, based on the findings, six mediatory experiences are suggested that facilitate preservice teachers’ growth.  Finally, the studies are assessed using a framework (Darling Hammond, 2006) to determine gaps in the research. Keywords: constructivism; Teacher Education; preservice teachers

Inferences of Parental Abilities Through Facial and Bodily Features

2021 ◽  
pp. 452-468
Author(s):  
Mitch Brown ◽  
Donald F. Sacco ◽  
Kaitlyn Boykin ◽  
Kelsey Drea ◽  
Alicia Macchione
Keyword(s):  
Physical Attractiveness ◽  
Good Genes ◽  
Trade Offs ◽  
Short And Long Term ◽  
Physical Features ◽  
Selection Of

This chapter explains that within the corpus of research showing the extent to which cues to physical attractiveness connote individuals’ specific value as a mate, findings have begun to recognize how these cues specifically apply to inferring parental abilities. Namely, this research suggests some physical features that were likely selected due to their connotations of heritable fitness may dually implicate a person as an especially effective parent. Such work additionally demonstrates the instances in which features not selected for their connotation of what we typically consider heritable fitness (i.e., adiposity) become desirable while providing additional evidence for the trade-offs in selecting short- and long-term mates. This selection of adiposity further clarified what is actually meant when researchers discuss selecting for good genes. That is, individuals could be inferring parental abilities through adiposity, thus leading individuals to select mates with higher levels for a long-term context given that connotation.

Acute Postoperative Pain

2017 ◽  
Author(s):  
Kelly Zach ◽  
Julio A. Gonzalez-Sotomayor
Keyword(s):  
Postoperative Pain ◽  
Patient Characteristics ◽  
Current Evidence ◽  
Long Term Outcomes ◽  
Acute Postoperative Pain ◽  
Analgesic Regimen ◽  
Potential Benefits ◽  
Short And Long Term ◽  
Selection Of

Inadequate management of acute postoperative pain increases morbidity and mortality. Poorly controlled pain results in delayed hospital discharge and may lead to the development of chronic pain. Current evidence supports the implementation of a multimodal analgesic regimen, where different pharmacologic and nonpharmacologic interventions are used. The selection of the different components of this multimodal analgesic approach should consider their potential benefits and limitations, as well as the unique patient characteristics and the surgical procedure. It is the responsibility of the perioperative health care provider to formulate an optimal pain management strategy to ultimately enhance patient satisfaction and improve short- and long-term outcomes.

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