COVID-19 vaccine acceptance among high-risk populations in Uganda

Background: Immunization is an important strategy for controlling the COVID-19 pandemic. COVID-19 vaccination was recently launched in Uganda, with prioritization to healthcare workers and high-risk individuals. In this study, we aimed to determine the acceptability of COVID-19 vaccine among persons at high risk of COVID-19 morbidity and mortality in Uganda. Methods: Between 29 March and 14 April 2021, we conducted a cross-sectional survey consecutively recruiting persons at high risk of severe COVID-19 (diabetes mellitus, HIV and cardiovascular disease) attending Kiruddu National Referral Hospital outpatient clinics. A trained research nurse administered a semi-structured questionnaire assessing demographics, COVID-19 vaccine related attitudes and acceptability. Descriptive statistics, bivariate and multivariable analyses were performed using STATA 16. Results: A total of 317 participants with a mean age 51.5 ± 14.1 years were recruited. Of this, 184 (60.5%) were female. Overall, 216 (70.1%) participants were willing to accept the COVID-19 vaccine. The odds of willingness to accept COVID-19 vaccination were four times greater if a participant was male compared with if a participant was female [adjusted odds ratio (AOR): 4.1, 95% confidence interval (CI): 1.8–9.4, p = 0.00]. Participants who agreed (AOR: 0.04, 95% CI: 0.01–0.38, p = 0.003) or strongly agreed (AOR: 0.04, 95% CI: 0.01–0.59, p = 0.005) that they have some immunity against COVID-19 were also significantly less likely to accept the vaccine. Participants who had a history of vaccination hesitancy for their children were also significantly less likely to accept the COVID-19 vaccine (AOR: 0.1, 95% CI: 0.01–0.58, p = 0.016). Conclusion: The willingness to receive a COVID-19 vaccine in this group of high-risk individuals was comparable to the global COVID-19 vaccine acceptance rate. Increased sensitization, myth busting and utilization of opinion leaders to encourage vaccine acceptability is recommended.

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Corowa-kun: Impact of a COVID-19 vaccine information chatbot on vaccine hesitancy, Japan 2021

10.1101/2021.05.26.21257854 ◽

2021 ◽

Author(s):

Takaaki Kobayashi ◽

Yuka Nishina ◽

Hana Tomoi ◽

Ko Harada ◽

Kyuto Tanaka ◽

...

Keyword(s):

Vaccine Hesitancy ◽

Cross Sectional Survey ◽

Confidential Interval ◽

Cross Sectional ◽

Vaccine Acceptance ◽

Factors Associated ◽

History Of ◽

Flu Vaccine ◽

Vaccine Information ◽

To Receive

Background: Few studies have assessed how mobile messenger apps affect COVID-19 vaccine hesitancy. We created a COVID-19 vaccine information chatbot in a popular messenger app in Japan to answer commonly asked questions. Methods: LINE is the most popular messenger app in Japan. Corowa-kun, a free chatbot, was created in LINE on February 6, 2021. Corowa-kun provides instant, automated answers to frequently asked COVID-19 vaccine questions. In addition, a cross-sectional survey assessing COVID-19 vaccine hesitancy was conducted via Corowa-kun during April 5 to 12, 2021. Results: A total of 59,676 persons used Corowa-kun during February to April 2021. Of them, 10,192 users (17%) participated in the survey. Median age was 55 years (range 16 to 97), and most were female (74%). Intention to receive a COVID-19 vaccine increased from 59% to 80% after using Corowa-kun (p < 0.01). Overall, 20% remained hesitant: 16% (1,675) were unsure, and 4% (364) did not intend to be vaccinated. Factors associated with vaccine hesitancy were: age 16 to 34 (odds ratio [OR] = 3.7, 95% confidential interval [CI]: 3.0-4.6, compared to age ≥ 65), female sex (OR = 2.4, Cl: 2.1-2.8), and history of another vaccine side-effect (OR = 2.5, Cl: 2.2-2.9). Being a physician (OR = 0.2, Cl: 0.1-0.4) and having received a flu vaccine the prior season (OR = 0.4, Cl: 0.3-0.4) were protective. Conclusions: Corowa-kun reduced vaccine hesitancy by providing COVID-19 vaccine information in a messenger app. Mobile messenger apps could be leveraged to increase COVID-19 vaccine acceptance.

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Willingness to receive future COVID-19 vaccines following the COVID-19 epidemic in Shanghai, China

BMC Public Health ◽

10.1186/s12889-021-11174-0 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Yehong Zhou ◽

Junjie Zhang ◽

Wenwen Wu ◽

Man Liang ◽

Qiang-Song Wu

Keyword(s):

Vaccine Safety ◽

Older Individuals ◽

Regression Analyses ◽

Pharmacological Interventions ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Factors Associated ◽

History Of ◽

Potential Factors ◽

To Receive

Abstract Background There are no pharmacological interventions currently available to prevent the transmission of SARS-CoV-2 or to treat COVID-19. The development of vaccines against COVID-19 is essential to contain the pandemic. we conducted a cross-sectional survey of Shanghai residents to understand residents’ willingness to be vaccinated with any future COVID-19 vaccines and take measures to further improve vaccination coverage. Methods We conducted a cross-sectional survey using self-administered anonymous questionnaires from 1 July to 8 September 2020. The main outcome was willingness of participants, and any children or older individuals living with them, to receive future COVID-19 vaccines. Logistic regression analyses were used to explore potential factors associated with vaccination willingness. Results A total of 1071 participants were asked about their willingness to receive future COVID-19 vaccines, for themselves and at least 747 children and 375 older individuals (≥60 years old) living with them. The highest proportion of expected willingness to vaccinate was among participants (88.6%), followed by children (85.3%) and older individuals (84.0%). The main reasons for reluctance to vaccinate among 119 participants were doubts regarding vaccine safety (60.0%) and efficacy (28.8%). Participants with a self-reported history of influenza vaccination were more likely to accept COVID-19 vaccines for themselves [adjusted odds ratio (OR) = 1.83; 95% confidence interval (CI): 1.19–2.82], their children (adjusted OR = 2.08; 95%CI: 1.30–3.33), and older individuals in their household (adjusted OR = 2.12; 95%CI: 1.14–3.99). Participants with older individuals in their families were less willing to vaccinate themselves (adjusted OR = 0.59; 95%CI: 0.40–0.87) and their children (adjusted OR = 0.58; 95%CI: 0.38–0.89). Conclusions Participants were more reluctant to accept COVID-19 vaccines for older individuals living with them. The presence of older individuals in the home also affected willingness of participants and their children to be vaccinated.

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1172. SARS-CoV-2 Vaccine Hesitancy in Caregivers of Hospitalized Children

Open Forum Infectious Diseases ◽

10.1093/ofid/ofab466.1365 ◽

2021 ◽

Vol 8 (Supplement_1) ◽

pp. S677-S677

Author(s):

Marisa Orbea ◽

Rachel Cunningham ◽

C Mary Healy ◽

Julie A Boom ◽

Claire Bocchini

Keyword(s):

Vaccine Uptake ◽

Vaccine Hesitancy ◽

Hospitalized Children ◽

Parent Attitudes ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Vaccine Acceptance ◽

And Behaviors ◽

Childhood Vaccines ◽

To Receive

Abstract Background SARS-CoV-2 vaccine hesitancy (VH) is hindering nationwide vaccination efforts; little is known about caregiver SARS-CoV-2 vaccine acceptance for children. We aimed to identify associations with SARS-CoV-2 VH in caregivers of hospitalized children. Methods We conducted a prospective cross-sectional survey in English and Spanish of caregiver COVID-19 knowledge, attitudes, behaviors, and associated VH among hospitalized children 6 months - 18 years at a large pediatric medical institution. Parents were approached daily, averaging 4-5 days/week, from 12/8/2020--4/5/2021. VH was assessed using the Parent Attitudes about Childhood Vaccines (PACV) survey; PACV score ≥50 denoted VH. Descriptive statistics and multivariable logistic regression were used. Responses were categorized. Results 295/307 (96%) of approached caregivers enrolled; 79% were ≥ 30 years, 68% were married/ living with a partner, and 57% had at least some college. 36% identified as white, 19% Black, and 46% Hispanic/ Latino. 53% of caregiver children had public insurance. 91% of caregivers self-reported their children were up to date with routine vaccines. 17% of caregivers were vaccine-hesitant overall. 50% of caregivers were willing to receive COVID-19 vaccine themselves. Figure 1 shows intention to vaccinate their child by PACV score. 65% knew someone who was hospitalized for COVID-19. 67% were scared of their child getting COVID-19. However, 49% were scared of their child getting the vaccine, 28% did not want to vaccinate their child and 27% were neutral in the intention to vaccinate their child. Caregivers who did not intend to vaccinate their child were more likely to be Black (27% vs. 16%, p=0.04) and less likely to be Hispanic/ Latino (33% vs. 49%, p=0.02). Table 1 shows attitudes, beliefs, and behaviors surrounding the COVID-19 pandemic and vaccine in caregivers who did or did not intend to vaccinate their child. Figure 1 COVID-19 vaccine uptake by PACV score Table 1 Caregiver attitudes, beliefs, and behaviors surrounding the COVID-19 pandemic and the COVID-19 vaccine Conclusion The majority of caregivers believe that SARS-CoV-2 vaccine will help control the pandemic, but less than half plan to vaccinate their children. A quarter of caregivers expressed uncertainty regarding the vaccine and therefore may be amenable to education and discussion. COVID-19 VH is different from VH towards routine vaccinations. More research is needed to address COVID-19 specific VH. Disclosures C. Mary Healy, MD, Dexcom (Shareholder)Intuitive (Shareholder)Quidel Corporation (Shareholder)Up to Date (Other Financial or Material Support, Honorarium)Vapotherm (Shareholder)

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Nursing students' attitudes, knowledge, and willingness to receive the COVID-19 vaccine: A cross-sectional study

10.1101/2021.05.24.21257710 ◽

2021 ◽

Author(s):

Ning Jiang ◽

Baojian Wei ◽

Hua Lin ◽

Youjuan Wang ◽

Shouxia Chai ◽

...

Keyword(s):

Nursing Students ◽

Side Effects ◽

Influencing Factors ◽

Family Members ◽

Cross Sectional Survey ◽

School Students ◽

Cross Sectional ◽

Vaccine Acceptance ◽

Academic Background ◽

To Receive

Aim: To investigate nursing students' konwledge, attitudes and willingness to receive the COVID-19 vaccine, and the influencing factors. Background: Vaccination is one of the effective measures to prevent COVID-19, but the vaccination acceptance varies across countries and populations. As reserve nurses, nursing students have both the professionalism of medical personnel and the special characteristics of school students, their attitudes, knowledge, and willingness to receive the COVID-19 vaccine may greatly affect the vaccine acceptance of the population now and in the future. But little research has been done on vaccine acceptance among nursing students. Design: A cross-sectional survey of nursing students was conducted via online questionnaires in March 2021. Methods: Descriptive statistics, independent sample t tests/one-way ANOVA (normal distribution), Mann-Whitney U tests/Kruskal-Wallis H tests (skewness distribution) and multivariate linear regression were performed. Results: The score rate of attitude, knowledge and vaccination willingness were 70.07%, 80.70% and 84.38% respectively. Attitude was significantly influenced by family economic conditions and whether a family member had been vaccinated. The main factors influencing knowledge were gender, grade and academic background. In terms of willingness, gender, academic background, visits to risk areas, whether family members were vaccinated, and whether they had side effects were significant influencing factors. Conclusions: The vaccine acceptance of nursing students was fair. Greater focus needed to be placed on the males, those of younger age, with a science background, and having low grades, as well as on students whose family members had not received the COVID-19 vaccine or had side effects from the vaccine. Targeted intervention strategies were recommended to improve vaccination rates.

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Medical History of Meat Handlers and the Occurrence of Zoonotic Mycobacterium bovis Infection in Imo State, Nigeria

Annual Research & Review in Biology ◽

10.9734/arrb/2019/v34i330153 ◽

2020 ◽

pp. 1-7

Author(s):

I. D. Stan-Ekezie ◽

O. C. Abanobi ◽

C. I. C. Ebirim ◽

Sally Ibe ◽

G. U. Onyeugo

Keyword(s):

Medical History ◽

Mycobacterium Bovis ◽

Sampling Technique ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Medical Checkup ◽

Imo State ◽

History Of ◽

Multistage Sampling ◽

Structured Questionnaire

A study on the medical history of meat handlers and the occurrence of zoonotic Mycobacterium bovis infection in Imo State, Nigeria was carried out using one thousand two hundred respondents. A cross sectional survey was carried out in the three (3) senatorial zones Imo state Nigerian and a multistage sampling technique was used to choose the abattoirs under study. A well structured questionnaire was distributed and the data analyzed. Results showed lack of BCG awareness (OR=0.174; P=0.017) to be statistically significant to the occurrence of bovine TB, on the other hand the range of the various times respondents go for medical checkups was considered; those who often attend medical checkup against those who always go for medical checkup (OR=16.187; P=<0.0001), also those who never go for medical checkup against those that had medical checkup three months ago (OR=1.910; P=<0.001). It was observed in this study that lack of BCG awareness and the care free attitude to medical checkup pose as a risk factor to Mycobacterium bovis T.B among meat handlers. Therefore, there is need to initiate an awareness program on the importance of BCG intake in the fight against Mycobacterium bovis T.B and improve existing diagnostic test to specifically deter early phase of the infection.

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Prevalence of stroke and stroke related risk factors: a population based cross sectional survey in southwestern China

10.21203/rs.2.17357/v4 ◽

2019 ◽

Author(s):

Xingyang Yi ◽

Hua Luo ◽

Ju Zhou ◽

Ming Yu ◽

Xiaorong Chen ◽

...

Keyword(s):

Risk Factors ◽

Family History ◽

High Risk ◽

Population Attributable Risk ◽

Southwestern China ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Stroke Population ◽

History Of ◽

Lack Of Exercise

Abstract Background: Stroke and its risk factors epidemiological survey can help identify individuals at higher risk and therefore promote stroke prevention strategies. The aim of this study was to estimate the current prevalence of stroke and high risk stroke population, and evaluate stroke associated risk factors in southwestern China. Methods: This was a multi-center, cross sectional survey in southwestern China from May 2015 to September 2015. The 8 communities were selected at random, and 17413 residents aged ≥ 40 years volunteered to participate in this survey. Data were collected through face-to-face survey using a structured questionnaire. 521 participants with incomplete questionnaires on stroke history or risk factors records were excluded. Results: A total of 16892 people included in analysis. The overall prevalence of stroke was 3.1% (95% CI 2.6% - 3.9%), 17.1% of participants were the high risk stroke population. After full adjustments, hypertension, diabetes, dyslipidemia, overweight, lack of exercise and family history of stroke were significantly associated with overall stroke and ischemic stroke. The largest contributor was hypertension (population-attributable risk 23.6%), followed by dyslipidemia, physical inactivity, family history of stroke, diabetes, and overweight. However, only hypertension (OR = 3.66, 95% CI 1.82-8.23) was significantly associated with hemorrhagic stroke. Conclusions: The prevalence of stroke and high risk stroke population was high among adults aged ≥ 40 years in southwestern China. Hypertension, dyslipidemia and lack of exercise were stronger contributors for stroke, these findings suggest that individual-level and population-level interventions for these leading risk factors are necessary to prevent stroke.

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Prevalence of stroke and stroke related risk factors: a population based cross sectional survey in southwestern China

BMC Neurology ◽

10.1186/s12883-019-1592-z ◽

2020 ◽

Vol 20 (1) ◽

Cited By ~ 4

Author(s):

Xingyang Yi ◽

Hua Luo ◽

Ju Zhou ◽

Ming Yu ◽

Xiaorong Chen ◽

...

Keyword(s):

Risk Factors ◽

Family History ◽

High Risk ◽

Population Attributable Risk ◽

Southwestern China ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Stroke Population ◽

History Of ◽

Lack Of Exercise

Abstract Background Stroke and its risk factors epidemiological survey can help identify individuals at higher risk and therefore promote stroke prevention strategies. The aim of this study was to estimate the current prevalence of stroke and high risk stroke population, and evaluate stroke associated risk factors in southwestern China. Methods This was a multi-center, cross sectional survey in southwestern China from May 2015 to September 2015. The eight communities were selected at random, and 17,413 residents aged ≥40 years volunteered to participate in this survey. Data were collected through face-to-face survey using a structured questionnaire. Five hundred twenty-one participants with incomplete questionnaires on stroke history or risk factors records were excluded. Results A total of 16,892 people included in analysis. The overall prevalence of stroke was 3.1% (95% CI 2.6–3.9%), 17.1% of participants were the high risk stroke population. After full adjustments, hypertension, diabetes, dyslipidemia, overweight, lack of exercise and family history of stroke were significantly associated with overall stroke and ischemic stroke. The largest contributor was hypertension (population-attributable risk 23.6%), followed by dyslipidemia, physical inactivity, family history of stroke, diabetes, and overweight. However, only hypertension (OR = 3.66, 95% CI 1.82–8.23) was significantly associated with hemorrhagic stroke. Conclusions The prevalence of stroke and high risk stroke population was high among adults aged ≥40 years in southwestern China. Hypertension, dyslipidemia and lack of exercise were stronger contributors for stroke, these findings suggest that individual-level and population-level interventions for these leading risk factors are necessary to prevent stroke.

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Perspective of Women in the Northern Netherlands on Support During Labor (of Childbirth) and the First Hours After Childbirth

International Journal of Childbirth ◽

10.1891/2156-5287.8.3.198 ◽

2018 ◽

Vol 8 (3) ◽

pp. 198-209

Author(s):

Tichelman Elke ◽

Carien I. Baas ◽

Frank Baarveld ◽

Joke M. Koelewijn

Keyword(s):

Pregnant Women ◽

Place Of Birth ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Birth Plan ◽

Support Provider ◽

Continuous Support ◽

The Moment ◽

To Receive ◽

Structured Questionnaire

AIMSTo quantify the preferences and preparations for support during labor and the first hours after childbirth of pregnant women and the specific preference for continuous support. To investigate the association with parity and the intended place of birth.DESIGNCross-sectional survey.METHODSTwelve midwifery practices in the northern Netherlands recruited pregnant women.Measurements of the structured questionnaire were preparation for childbirth and preference for support (timing, including continuous support, provider, and type of support)RESULTSTwo hundred and five of the 247 eligible women participated. Nulliparae, significantly more often than multiparae, aimed to prepare themselves by attending prenatal classes (63% vs. 21%) and by creating a birth plan (59% vs. 40%). Women preferred to receive various types of support during childbirth from their partner (100%), midwife (95%), Maternity Care Assistant (29%), and nurse (15%). The women preferred the midwife to be present from the moment the midwife (48%) or the woman herself (22%) indicated a need for the midwife. Among the participants, 10% of the women preferred continuous support from 4 cm dilation.CONCLUSIONWe consider the best approach to continuous support to be that it should be available on request rather than either not being available or being the standard care.

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Acceptability of a COVID-19 Vaccine among the Saudi Population

Vaccines ◽

10.3390/vaccines9030226 ◽

2021 ◽

Vol 9 (3) ◽

pp. 226

Author(s):

Eman Ibrahim Alfageeh ◽

Noor Alshareef ◽

Khadijah Angawi ◽

Fahad Alhazmi ◽

Gowokani Chijere Chirwa

Keyword(s):

Seasonal Influenza ◽

Saudi Population ◽

Cross Sectional Survey ◽

Kingdom Of Saudi Arabia ◽

Cross Sectional ◽

Vaccine Refusal ◽

Raising Awareness ◽

History Of ◽

Multifaceted Interventions ◽

To Receive

To investigate the associated factors underlying vaccination intentions for Coronavirus Disease 2019 (COVID-19), an online cross-sectional survey was conducted among adults 18 years or over in the Kingdom of Saudi Arabia. Data were collected between 8 and 14 December 2020. A logistic regression analysis was employed to examine and identify the variables associated with vaccination intentions for COVID-19, with the odds ratio (OR) and 95% confidence interval (CI) also calculated. A total of 2137 respondents completed the questionnaire. Overall, about 48% of Saudi adults were willing to receive the COVID-19 vaccine. Participants had stronger intentions to receive a vaccination if they resided in the southern region (OR: 1.95; 95% CI: 1.21–3.14), received the seasonal influenza vaccination in the past (OR: 1.52; 95% CI: 1.17–1.97), believed in mandatory COVID-19 vaccination (OR: 45.07; 95% CI: 31.91–63.65), or reported high levels of concern about contracting COVID-19 (OR: 1.91; 95% CI: 1.29–2.81). Participants were less likely to have an intention to be vaccinated if they had a history of vaccine refusal (OR: 0.28; 95% CI: 0.19–0.40). The low acceptance rate among the Saudi population should be targeted with multifaceted interventions aimed at raising awareness and emphasizing the safety and efficacy of the COVID-19 vaccine.

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