An Evidence-Based Study on Medicinal Plants for Hemorrhoids in Medieval Persia

Hemorrhoids is one of the most common gastrointestinal diseases. There are several therapeutic options associated with some complications. Therefore, researchers look for traditional medicines as a potential resource for introduction of new natural drugs. The current study reports an evidence-based review of herbal remedies for hemorrhoids in traditional Persian medicine. A comprehensive survey about hemorrhoids on the most important manuscripts of traditional Persian medicine was done. Then, scientific data banks were searched for possible related properties of each herb in the conventional medicine. We reported some historical aspects of traditional Persian medicine view on classification, examination, and predisposing factors of hemorrhoids. In addition, we have reported 105 medicinal plants belonging to 51 families. More than half of the reported herbs exhibited anti-inflammatory and analgesic effects. Although lack of human studies regarding the mentioned herbs is noted, positive results from experimental findings can be considered for new drug discovery supported by traditional and medieval experiences.

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An Evidence-Based Review of Antitussive Herbs Containing Essential Oils in Traditional Persian Medicine

Current Drug Discovery Technologies ◽

10.2174/1568009620666200421091245 ◽

2020 ◽

Vol 17 ◽

Cited By ~ 1

Author(s):

Ayda Hosseinkhani ◽

Bijan Ziaeian ◽

Kamran Hessami ◽

Mohammad Mehdi Zarshenas ◽

Ali Kashkooe ◽

...

Keyword(s):

Medicinal Plants ◽

Essential Oils ◽

Scientific Evidence ◽

Herbal Remedies ◽

Future Research ◽

Evidence Based ◽

Online Databases ◽

Persian Medicine ◽

Troublesome Symptom ◽

Traditional Persian Medicine

Background: Cough is one of the most common medical symptoms for which medical advice is sought. Although cough is a protective reflex responsible for clearing the airways from secretions and foreign bodies, it can be a troublesome symptom that causes discomfort to patients. Due to the increasing interest in herbal remedies in the both developed and developing countries, in the current study, we aimed to overview medicinal herbs containing essential oils used as antitussive agents according to the Traditional Persian Medicine [TPM] textbooks. We summarized the relevant scientific evidence on their possible pharmacological actions. Methods: To collect the evidence for treatment of cough or “seaal” [cough in ancient books] from TPM sources, five main medicinal Persian manuscripts were studied. The antitussive herbs were listed and their scientific names were identified and authenticated in accordance with botanical reference books. ScienceDirect and PubMed online databases were searched for related mechanisms of action of the reported medicinal plants. Results: The number of 49 herbs containing essential oils were recommended in TPM for the treatment of cough; 21 of them had at least one known mechanism of action for cough suppression in the scientific literature. According to this review, most of the cited medicinal plants were assessed for either nitric oxide inhibitory or antitussive/expectorant activities. Conclusion: In addition to advantageous effects of antitussive herbs noted by TPM, the present review highlighted some recent evidence-based data on these promising candidates that could be used as an outline for future research on their medicinal use.

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An Evidence-based Study on Pharmacological Treatments of Non-Alcoholic Fatty Liver Disease Based on Traditional Persian Medicine

Current Traditional Medicine ◽

10.2174/2215083805666190902114137 ◽

2020 ◽

Vol 6 (3) ◽

pp. 188-202

Author(s):

Fatemeh Sadat Hasheminasab ◽

Haleh Tajadini ◽

Mohammad Setayesh

Keyword(s):

Liver Disease ◽

Medicinal Plants ◽

Fatty Liver ◽

Fatty Liver Disease ◽

Current Evidence ◽

Evidence Based ◽

Alcoholic Fatty Liver ◽

Persian Medicine ◽

Traditional Persian Medicine ◽

Alcoholic Fatty Liver Disease

Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the most prevalent liver diseases regarded as the primary cause of chronic liver disease, which may lead to hepatic failure. Despite the recent developments in the treatment of NAFLD, the necessity to find more efficient treatments has led to investigation on medicinal plants. Traditional Persian Medicine (TPM) is one of the oldest medical schools in the world. For treatment of NAFLD, different medicinal plants have been employed in TPM. Objective: Considering the public welcome for herbal medicines, the current evidence-based review study is conducted to investigate herbal remedies for NAFLD in TPM. Methods: Medicinal plants for treating NFALD were extracted according to three famous textbooks of Persian medicine. Then anti-obesity, hypolipidemic, hypoglycemic, antioxidative and hepatoprotective effects of these medicinal plants were investigated according to modern medicine. For this purpose, databases including Scopus, web of sciences, Pubmed, Google scholar and science direct were searched. Results: Investigations of Persian medicine textbooks resulted in deriving 53 herbs, which are useful for treating NAFLD. Searching through aforesaid databases showed that most of these plants can help to treat this disease in at least 2 ways. 25 herbs are effective in all 5 mentioned effects. Conclusion: It should be considered that in Persian medicine, first-line treatment is correction of life style, then if necessary, herbs are prescribed. However, this study showed that many herbs mentioned in Persian medicine for treatment of NAFLD might have a potential to aid patient with this disease.

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Herbal Medicine for Oligomenorrhea and Amenorrhea: A Systematic Review of Ancient and Conventional Medicine

BioMed Research International ◽

10.1155/2018/3052768 ◽

2018 ◽

Vol 2018 ◽

pp. 1-22 ◽

Cited By ~ 9

Author(s):

Arezoo Moini Jazani ◽

Kobra Hamdi ◽

Mojgan Tansaz ◽

Hossein Nazemiyeh ◽

Homayoun Sadeghi Bazargani ◽

...

Keyword(s):

Systematic Review ◽

Medicinal Plants ◽

Conventional Medicine ◽

Library Science ◽

Reproductive Age ◽

Cochrane Library ◽

Foeniculum Vulgare ◽

Iranian Traditional Medicine ◽

Persian Medicine ◽

Traditional Persian Medicine

Introduction. Menstrual bleeding cessation is one of the most frequent gynecologic disorders among women in reproductive age. The treatment is based on hormone therapy. Due to the increasing request for alternative medicine remedies in the field of women’s diseases, in present study, it was tried to overview medicinal plants used to treat oligomenorrhea and amenorrhea according to the pharmaceutical textbooks of traditional Persian medicine (TPM) and review the evidence in the conventional medicine. Methods. This systematic review was designed and performed in 2017 in order to gather information regarding herbal medications of oligomenorrhea and amenorrhea in TPM and conventional medicine. This study had several steps as searching Iranian traditional medicine literature and extracting the emmenagogue plants, classifying the plants, searching the electronic databases, and finding evidences. To search traditional Persian medicine references, Noor digital library was used, which includes several ancient traditional medical references. The classification of plants was done based on the repetition and potency of the plants in the ancient literatures. The required data was gathered using databases such as PubMed, Scopus, Google Scholar, Cochrane Library, Science Direct, and web of knowledge. Results. In present study of all 198 emmenagogue medicinal plants found in TPM, 87 cases were specified to be more effective in treating oligomenorrhea and amenorrhea. In second part of present study, where a search of conventional medicine was performed, 12 studies were found, which had 8 plants investigated: Vitex agnus-castus, Trigonella foenum-graecum, Foeniculum vulgare, Cinnamomum verum, Paeonia lactiflora, Sesamum indicum, Mentha longifolia, and Urtica dioica. Conclusion. Traditional Persian medicine has proposed many different medicinal plants for treatment of oligomenorrhea and amenorrhea. Although just few plants have been proven to be effective for treatment of menstrual irregularities, the results and the classification in present study can be used as an outline for future studies and treatment.

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An Evidence-Based Research on Botanical Sources for Oral Mucositis Treatment in Traditional Persian Medicine

Current Drug Discovery Technologies ◽

10.2174/1570163817666200203110803 ◽

2020 ◽

Vol 17 ◽

Author(s):

Fatemeh Sadat Hasheminasab ◽

Fariba Sharififar ◽

Seyed Mehdi Hashemi ◽

Mohammad Setayesh

Keyword(s):

Oral Mucositis ◽

Punica Granatum ◽

Economic Consequences ◽

Herbal Remedies ◽

Current Evidence ◽

Evidence Based ◽

Cancer Therapies ◽

Persian Medicine ◽

Comprehensive Survey ◽

Traditional Persian Medicine

Background: Cancer is one of the most prevalent diseases associated with heavy complications in treatment. Mucotoxic cancer therapies such as head and neck radiotherapy and some of the chemotherapy agents may lead to oral mucositis. In addition to its economic consequences, mucositis also affects patients' quality of life. In traditional Persian medicine (TPM) manuscripts, several medicaments have been suggested for treatment of mucositis. Objective: Considering the public welcome for herbal medicine, the current evidence-based review study is conducted to investigate the herbal remedies which have been proposed for oral mucositis in TPM. Methods: At first, a comprehensive survey was done on Qanon fi al-Teb which is the most important textbook of TPM; then the scientific name of the herbs was authenticated according to the botanical textbooks. At last, data banks including Scopus, Pubmed, Web of science and Science direct were investigated for possible relevant properties of each medicinal plant in the literature. Results: Totally 30 herbs are introduced in this study. According to the registered documents, 18 herbs are reported to have antioxidant, anti-inflammatory, antimicrobial, anti-nociceptive and wound healing properties of which the therapeutic effect of only a few herbs including Glycyrrhiza glabra, Malva sylvestris, Morus nigra, Punica granatum, and Solanum nigrum were directly evaluated against oral mucositis on the literature. Conclusion: Despite the lack of human studies on mucositis for the other discussed herbs, their related pharmacological properties can be considered for new natural drug discovery supported by medieval and traditional experiments.

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A Mini-review on Medicinal Plants Used for the Treatment of Jaundice in the Canon of Medicine

Shiraz E-Medical Journal ◽

10.5812/semj.102127 ◽

2021 ◽

Vol In Press (In Press) ◽

Author(s):

Jamileh Mahdavi Jafari ◽

Shahdis Barimani ◽

Fatemeh Aliasl ◽

Ghazaleh Heydarirad ◽

Mehdi Pasalar

Keyword(s):

Clinical Study ◽

Medicinal Plants ◽

Mechanism Of Action ◽

Recent Literature ◽

Herbal Remedies ◽

Supportive Evidence ◽

Medical Systems ◽

Persian Medicine ◽

Traditional Persian Medicine ◽

System Disorder

Context: Jaundice is a common gastrointestinal system disorder globally. Considering the potential of herbal remedies in traditional medical systems, this study was performed to explore medicinal plants used for the treatment of jaundice in the Canon of medicine. Evidence Acquisition: This narrative review was done on one of the most important textbooks in traditional Persian medicine. Different keywords, like Yaraghan and Zardi, were searched in the book, and a list of plants used was prepared. We searched for recent literature to find any supportive evidence to find the established mechanism of action, as well. Results: At the end of the study, 32 plants were found in the Canon of medicine, which most of them had at least one experimental or clinical study clarifying their mechanism of action to treat jaundice or decrease bilirubin. Conclusions: There are potential remedies in traditional Persian medicine resources, which may be useful in future trials to treat jaundice.

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Bloating

Journal of Evidence-Based Complementary & Alternative Medicine ◽

10.1177/2156587215622915 ◽

2016 ◽

Vol 21 (2) ◽

pp. 154-159 ◽

Cited By ~ 5

Author(s):

Mohsen Naseri ◽

Mahmoud Babaeian ◽

Farzaneh Ghaffari ◽

Mohammad Kamalinejad ◽

Awat Feizi ◽

...

Keyword(s):

Medicinal Plants ◽

Literature Review ◽

Modern Medicine ◽

Scientific Data ◽

Nasal Discharge ◽

Persian Medicine ◽

Traditional Persian Medicine ◽

Place Of Origin ◽

Review Study ◽

Digestive Disorders

Bloating and abdominal distention are common complaints present in quite a number of organic and functional diseases. An important subject in traditional Persian medicine is digestive disorders, particularly bloating and its etiology. This is a literature review study conducted on The Canon in Medicine written by Avicenna and using the keywords: bloating, gas. In this article, causes for bloating, according to Avicenna, include diet causes, inappropriate lifestyle, gastrointestinal, and miscellaneous reasons. These were compared with causes suggested in modern medicine. Avicenna classifies causes based on the place of origin into upper part of the abdomen (stomach) and intestinal part of the abdomen. Also, 38 medicinal plants used as remedies were listed. Modern scientific data support all bloating causes that have been mentioned in the canon. Obviously, some causes such as uterine disorders and posterior nasal discharge need to be studied further.

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