scholarly journals Association Between Vitamin A Intake and Disease Severity in Early-Onset Heterotopic Ossification of the Posterior Longitudinal Ligament of the Spine

2021 ◽  
pp. 219256822198930
Author(s):  
Tsutomu Endo ◽  
Shiro Imagama ◽  
Satoshi Kato ◽  
Takashi Kaito ◽  
Hiroaki Sakai ◽  
...  
Keyword(s):  
Vitamin A ◽  
Early Onset ◽  
Dietary Habits ◽  
Vitamin A Deficiency ◽  
Serum Vitamin ◽  
Posterior Longitudinal Ligament ◽  
Cross Sectional Study ◽  
Onset Age ◽  
Cross Sectional ◽  
Lifestyle Related Diseases

Study Design: A sex- and age-matched case-control study and a cross-sectional study. Objective: In our previous study, patients with early-onset (<50 years of age) ossification of the posterior longitudinal ligament (OPLL) had distinct features such as morbid obesity, a high prevalence of lifestyle-related diseases, and diffuse ossified lesions mainly affecting the thoracic spine. Our goals were to determine whether early-onset OPLL patients have unbalanced dietary habits and to identify nutritional factors associated with OPLL exacerbation. Methods: In Study 1, the simple brief-type self-administered diet history questionnaire (BDHQ) was used to compare nutrient intake levels of early-onset OPLL patients (n = 13) with those of sex- and age-matched non-OPLL controls (n = 39) or with those of common OPLL (onset age ≥ 50 years, n = 62). In Study 2, serological validation was conducted for thoracic OPLL patients (n = 77) and non-OPLL controls (n = 101) in a nationwide multicenter study in Japan. Results: The BDHQ showed that the early-onset OPLL patients had significantly lower intakes of vitamins A and B6 than non-OPLL controls. These results were validated by lower serum vitamins A and B6 levels in the early-onset thoracic OPLL patients. The severity of OPLL negatively correlated with serum vitamin A levels in male early-onset OPLL patients. The multiple regression analysis revealed that the severity of thoracic OPLL had an association with onset age and serum vitamin A level. Conclusions: Vitamin A deficiency resulting from unbalanced dietary habits is associated with exacerbation of male early-onset OPLL.

Impact of Giardia Intestinalis on Vitamin A Status in Schoolchildren from Northwest Mexico

2008 ◽  
Vol 78 (2) ◽  
pp. 51-56 ◽  
Author(s):  
Quihui-Cota ◽  
Astiazarán-García ◽  
Valencia ◽  
Morales-Figueroa ◽  
Lopez-Mata ◽  
...  
Keyword(s):  
Vitamin A ◽  
Family Income ◽  
Vitamin A Deficiency ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Serum Retinol ◽  
Cross Sectional ◽  
School Breakfast Program ◽  
Northwest Mexico ◽  
Daily Intakes

We conducted a cross-sectional study in northwest Mexico in order to investigate the association between giardiasis and serum vitamin A in 40 Giardia-infected and 70 Giardia-free schoolchildren who were covered by a regional school breakfast program. There were no significant differences in age, Z-scores for nutritional indices of height for age, weight for age, or weight for height, socioeconomic conditions (employment and education of the parents, household conditions, sanitation facilities, type of drinking water, and family income), and mean daily intakes of vitamin A in the Giardia-free (899 ± 887 μg) and the Giardia-infected (711 ± 433 μg) groups. A higher concentration of serum retinol was found in the Giardia-free group than in the Giardia-infected group (0.75 μmol/L versus 0.61 μmol/L, respectively; p < 0.0001). Giardia-infected children were more likely to be vitamin A-deficient than the Giardia-free children (OR = 3.2; 95% CI = 1.2–8.5). Although 95% of the children met the daily-recommended intakes of vitamin A, half of them showed subclinical vitamin A deficiency. It is recognized that vitamin A deficiency is multifactorial and giardiasis was a factor significantly associated with this deficiency in this study. Mexican program developers and policymakers should be aware about the distinction between dietary deficiencies and deficiency diseases when current national program strategies for parasitic control and vitamin A supplementation are redesigned.

scholarly journals Evaluation of the effectiveness of the national vitamin A supplementation programme among school children in Sri Lanka

2007 ◽  
Vol 97 (1) ◽  
pp. 153-159 ◽  
Author(s):  
Thennakoon M. J. C. Madatuwa ◽  
Sanath T. C. Mahawithanage ◽  
Udumalagala G. Chandrika ◽  
Errol R. Jansz ◽  
Ananda R. Wickremasinghe
Keyword(s):  
Sri Lanka ◽  
Vitamin A ◽  
School Children ◽  
Vitamin A Deficiency ◽  
Serum Vitamin ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Vitamin A Supplementation ◽  
Concentration Estimation

The Ministry of Health in Sri Lanka commenced a vitamin A supplementation programme of school children with a megadose of 105 μmol (100 000 IU) vitamin A in school years 1, 4 and 7 (approximately 5-, 9- and 12-year-olds, respectively) in 2001. We evaluated the vitamin A supplementation programme of school children in a rural area of Sri Lanka. A cross-sectional study was conducted among children supplemented with an oral megadose of vitamin A (105 μmol; n 452) and children not supplemented (controls; n 294) in Grades 1–5. Children were clinically examined and a sample of blood was taken for serum vitamin A concentration estimation by HPLC. Socio-demographic information was obtained from children or mothers. Supplemented children had a higher proportion of males and stunted children, were younger and lived under poorer conditions as compared to controls. There was no difference in the prevalences of eye signs and symptoms of vitamin A deficiency in the two groups. Supplemented children had higher serum vitamin A concentrations than controls (1·4 (sd 0·49) μmol/l v. 1·2 (sd 0·52) μmol/l). The serum vitamin A concentrations were 1·6 (sd 0·45), 1·4 (sd 0·50), 1·3 (sd 0·44) and 1·1 (sd 0·43) μmol/l in children supplemented within 1, 1–6, 7–12 and 13–18 months of supplementation, respectively. Vitamin A concentrations were significantly greater than controls if supplementation was carried out within 6 months after adjustment. The oral megadose of 105 μmol vitamin A maintained serum vitamin A concentrations for 6 months in school children.

scholarly journals Awareness about breast feeding practices and vitamin A deficiency among mothers in Srikakulam district of Andhra Pradesh, South India

2021 ◽  
Vol 8 (5) ◽  
pp. 2346
Author(s):  
Vasantha Rao Sappati ◽  
Sannapaneni Krishnaiah ◽  
Suneetha Sapur
Keyword(s):  
Vitamin A ◽  
Breast Feeding ◽  
Andhra Pradesh ◽  
Vitamin A Deficiency ◽  
Sampling Strategy ◽  
Signs And Symptoms ◽  
Feeding Practices ◽  
Population Based ◽  
Cross Sectional Study ◽  
Cross Sectional

Background: To assess the awareness about breast feeding practices and to assess the knowledge, attitude and practice about the signs and symptoms of vitamin A deficiency (VAD) and vitamin A rich foods intake among mothers of children below 5 years in the Srikakulam district of Andhra Pradesh (AP) in South India.Methods: A population based cross-sectional study was conducted on 284 mothers (age range 14 to 36 years) during June 2011 and September 2011. A combined simple and systematic random sampling strategy was used to select mothers from one tribal, rural and semi urban area with a representative sample of the Srikakulam district. A standardized structured questionnaire that was developed and validated by the National institute of nutrition, Hyderabad was utilized for this study.Results: The awareness of vitamin A and night blindness was 68.7% (95% confidence intervals (CI): 62.9–74.0) (n=195) and 93.7% (95% CI: 90.2–96.2) (n=266) respectively. The knowledge of signs and symptoms of vitamin A deficiency (VAD) was nil among illiterate mothers and low among literates; with primary education, adjusted odds ratio (OR): 0.01 (95% CI: 0.00, 0.06) and with secondary education, OR: 0.19 (95% CI: 0.06, 0.62) compared to mothers with graduation and above.Conclusions: There is a need to increase the awareness and knowledge about VAD among mothers with children below 5 years in the southern state of AP.

Prevalence of Vitamin A Deficiency And Associated Factors Among Children Aged 6-59 Months In Dera District, Northwest Ethiopia: A Cross-Sectional Study

2020 ◽  
Author(s):  
Yidrsail Hune ◽  
Hirut Asaye ◽  
Ayenew Negesse ◽  
Habtamu Temesgen ◽  
Tadesse Yirga ◽  
...  
Keyword(s):  
Vitamin A ◽  
Birth Interval ◽  
Associated Factors ◽  
Vitamin A Deficiency ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Potential Health

Abstract Background: Vitamin A is a fat-soluble vitamin essential for the proper functioning of the immune system. It fondes both animal and plant sources in the form of retinol from animal sources or beta-carotene from plant source foods. Due to increased nutrient need and the severity of the potential health consequences are associated with vitamin A deficiency (VAD), preschool children and pregnant women are considered as the most at risk segments of the community. Hence, this study aimed to assess the prevalence of VAD and associated factors among children aged 6-59 months in Dera woreda, Northwest Ethiopia. Methods: Community based quantitative cross-sectional study was conducted among children aged 6-59 months in Dera woreda from December 1/2018 to January 1/2019. Multistage random sampling was used to select the required samples (267). Data were coded and entered into Epi-data version 3.1 and exported to SPSS (Statistical Package for Social Sciences) version 20 for analysis. Binary logistic regression was fitted. Both bivariable and multivariable analyses were used to identify factors associated with VAD. Those variables that were showed significant association in multivariable association at P value less than 0.05 declared as statistically significant factors of VAD among children age 6-59 months. Results: Two hundred sixty seven mother-children Pairs were included in the study making a response rate of 94.7%. The overall prevalence of Vitamin A deficiency among children age 6-59 months was 7.8% (95% CI (4.7, 11.3). Antenatal care follow up (AOR: 0.446,95 % CI (0.155, 0.980)); birth interval within 2 year (AOR: 0.392, 95 % CI (0.107, 0.839)), and age group of24-35 months (AOR; 1.206, 95 % CI (1.037, 6.129)) were significantly associated with vitamin-A deficiency. Conclusion: The overall prevalence of vitamin A deficiency in this study was found to be lower than the national and regional prevalence. According to this study, VAD is a mild public health problem. Age of children, birth interval, ANC follow up, remain the most important associated factors for vitamin A deficiency. Therefore to decrease the prevalence of VAD, ANC service should be strengthened and we should focus on older children birth interval and age- based food needs.

scholarly journals Uptake of routine vitamin A supplementation for children in Humbo district, southern Ethiopia: community-based cross-sectional study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Getnet Kassa ◽  
Addisalem Mesfin ◽  
Samson Gebremedhin
Keyword(s):  
Preschool Children ◽  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Economic Status ◽  
Cross Sectional Study ◽  
Southern Ethiopia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin A Supplementation ◽  
Socio Economic Status

Abstract Background In low- and middle-income countries routine vitamin A supplementation (VAS) is a key strategy for reducing vitamin A deficiency and mortality and morbidity of preschool children. However, in Ethiopia, there is paucity of evidence regarding the level and determinants of the uptake of the supplement. This study was designed to assess the coverage and predictors of VAS among preschool children in Humbo district, Southern Ethiopia. Methods A cross-sectional study was conducted in April 2016. A total of 840 mothers/caregivers having children 6–59 months of age were selected using multistage cluster sampling technique from six rural villages implementing routine VAS program. Data were collected using interviewer administered questionnaire. Possible predictors considered in the study include distance from the nearby health facility, household socio-economic status, type of the household (model vs non-model), maternal access to health education on VAS, and knowledge on vitamin A and VAS. Multivariable logistic regression analysis was performed to identify predictors of uptake of VAS. The outputs are presented using adjusted odds ratio (AOR) with the respective 95% confidence interval (CI). Results The coverage of VAS was 75.0% (95% CI: 72.1–77.9). Better knowledge of mothers about the importance of the supplement (AOR: 1.49, 1.02–2.17), obtaining VAS related information from frontline community health workers (AOR: 1.51, 1.34–2.72) than health professionals and being from households in the “rich” wealth tertile (AOR: 1.80, 95% CI: 1.07–3.03) were positively associated with uptake VAS. Conclusion The VAS coverage of the area was approaching the expected national target of 80%. However, the uptake can be enhanced though awareness creation and improving socio-economic status of the community.

scholarly journals Prevalence of Vitamin A Deficiency And Associated Factors Among Children Aged 6-59 Months In Dera District, Northwest Ethiopia: A Cross-Sectional Study

2021 ◽  
Vol 6 (2) ◽  
Keyword(s):  
Vitamin A ◽  
Birth Interval ◽  
Associated Factors ◽  
Vitamin A Deficiency ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Natal Care

Background: Vitamin A is a fat-soluble vitamin. It comes retinol from animal sources or beta-carotene from plant source. Vitamin A contains breast milk after the post-weaning period and their increased nutrient demand of children from 6-59 months, they are considered highly affected segments of the community. Hence, study assesses vitamin A deficiency and associated factors among children aged 6-59 months in Dera district, Northwest Ethiopia. Methods: Cross-sectional study design was conducted via multistage sampling techniques. Data were coded and entered into Epi-data version 3.1 and exported to Statistical Package for the Social Sciences (SPSS) version 20 for analysis. The bivariate and multiple variable logistic regression analyses were fitted. Results: Total response rate 94.7%. Prevalence of vitamin A deficiency among children age from 6-59 months was 7.8% (95% CI: 4.7, 11.3). Anti natal care (ANC) follow-up (AOR =0.446:95 % CI; 0.155, 0.980), and birth interval (AOR= 0.392: 95 % CI; 0.107, 0.839), reduces the odds of developing vitamin A deficiency; whereas age group of 36–47 months (AOR= 1.911: 95 % CI; 1.305, 11.969) increases the odds of its deficiency. Conclusion: Age of children, birth interval, ANC follow-up, Post natal care (PNC) follow-up, and place of residence were associated factors for vitamin A deficiency. Therefore more efforts should be encouraged to produce and purchase a variety of foods rich in vitamin A.

scholarly journals Factors influencing the uptake of pulse vitamin A supplementation among children in a rural area in India: a cross sectional study

2019 ◽  
Vol 7 (1) ◽  
pp. 61
Author(s):  
Vinod K. Ramani ◽  
Anand Lakshman
Keyword(s):  
Vitamin A ◽  
Technical Assistance ◽  
Health Workers ◽  
Vitamin A Deficiency ◽  
Health Department ◽  
Cross Sectional Study ◽  
Leafy Vegetables ◽  
Cross Sectional ◽  
Vitamin A Supplementation ◽  
Factors Influencing

Background: The change in strategy of India’s National Program for the prevention and control of nutritional blindness due to Vitamin A deficiency during 2006, aims for all children aged 9 months to 5 years to receive biannual pulse dose of Vitamin A with a total nine mega doses of Vitamin A. Micronutrient initiative (MI) was providing technical assistance to the State Health department of Karnataka in implementing the new bi-annual strategy, in partnership with UNICEF during the period 2006 to 2010.Methods: During July 2006, the Investigator evaluated its coverage in Gulbarga district. This study assessed the factors influencing the uptake of pulse Vitamin A supplementation (VAS) among children from impoverished background. Using oral questionnaires, a total of 30 Parents (Mothers) of these children, 12 childcare workers (AWWs), 12 peripheral health workers (ANMs) were interviewed regarding barriers towards implementing this Program and assessment of the facilities (12 Anganwadi centres) were conducted.Results: Only 28% of the facility had some IEC display regarding VAS. 75% of ANMs were aware that either green leafy vegetables or fish or fruits are the main source of micronutrients. A similar number of ANMs knew that Vitamin A deficiency causes night blindness, >90% of AWW had informed parents about the program during the monthly mother meetings. <20% of parents were aware of the current pulse VAS program and a similar number were aware of the next round of supplementation.Conclusions: Regular interaction with families, monitoring the activities of field level health workers and supportive supervision will enable uptake of VAS Program. Future action should prioritize sub-district level units – blocks and villages, with higher concentration of poor households.

scholarly journals Knowledge of parents and coverage among children regarding vitamin A in day care centers

2017 ◽  
Vol 4 (11) ◽  
pp. 4141
Author(s):  
Nidhi Sharma ◽  
Vineet Kaur Ahuja ◽  
Siriesha .
Keyword(s):  
Vitamin A ◽  
Day Care ◽  
Vitamin A Deficiency ◽  
Cross Sectional Study ◽  
Sources Of Information ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin A Supplementation ◽  
Day Care Centers ◽  
Knowledge And Practice

Background: Vitamin A deficiency (VAD) is one of the most significant causes of preventable childhood blindness. The present study was conducted among parents of pre-school children to study knowledge and practice regarding vitamin A intake and coverage of Vitamin A supplementation among them. Methods: It was a cross sectional study conducted in Patiala city of Punjab. Interview was conducted among parents of 275 preschool children going to various day care centers in Patiala. Results: It was found in this study that 56.7% had knowledge regarding Vitamin A supplementation. Less than half of the parents knew about vitamin A rich foodstuffs. Conclusions: From the present study we can conclude that there is a wide gap regarding knowledge and coverage about vitamin A supplementation. Doctors and books were main sources of information. 

scholarly journals Association Between Serum Vitamin A Levels and Recurrent Respiratory Tract Infections in Children

2021 ◽  
Vol 9 ◽  
Author(s):  
Xiaoyan Wang ◽  
Xingming Li ◽  
Chunhua Jin ◽  
Xinyuan Bai ◽  
Xinran Qi ◽  
...  
Keyword(s):  
Vitamin A ◽  
Respiratory Tract ◽  
Children And Adolescents ◽  
Respiratory Tract Infections ◽  
Vitamin A Deficiency ◽  
Serum Vitamin ◽  
Cross Sectional ◽  
Subclinical Vitamin ◽  
Tract Infections ◽  
Recurrent Respiratory Tract Infections

To evaluate the association between serum vitamin A levels and the prevalence of recurrent respiratory tract infections (RRTIs) in children and adolescents and to provide evidence that would help decrease the prevalence of respiratory tract infections (RTIs) in children. This cross-sectional study included 8034 children and adolescents in Beijing aged 6 months to 17 years. RRTI and RTI symptoms were diagnosed according to the Clinical Concept and Management of Recurrent Respiratory Tract Infections in Children. Multivariate logistic regression models were used to evaluate the association between serum vitamin A levels and RRTIs after adjusting for potential confounders. Among the included children, 721 (8.97%) were diagnosed with vitamin A deficiency, whereas 3,073 (38.25%) were diagnosed with subclinical vitamin A deficiency. Only 28.8% (208/721) of children with vitamin A deficiency and 53.1% (1,631/3,073) of children with subclinical vitamin A deficiency had no RRTI and RTI symptoms, respectively. Compared with children with normal vitamin A levels, those with vitamin A deficiency and subclinical vitamin A deficiency had a greater risk for RRTIs, with an odds ratio (OR) of 6.924 [95% confidence interval (CI): 5.433–8.824] and 2.140 (95% CI: 1.825–2.510), respectively]. Vitamin A levels were also positively associated with RTI symptoms, with those having vitamin A deficiency and subclinical vitamin A deficiency showing an OR of 1.126 (95% CI: 0.773–1.640) and 1.216 (95% CI: 1.036–1.427), respectively. The present cross-sectional study found that low serum vitamin A levels were significantly associated with RRTI or RTI prevalence in children and adolescents.

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