scholarly journals STUDIES ON HYPOPROTEINEMIA. I. HYPOPROTEINEMIA IN PATIENTS WITH GASTRIC CANCER; ITS PERSISTENCE AFTER OPERATION IN THE PRESENCE OF BODY TISSUE REPLETION

Blood ◽  
1948 ◽  
Vol 3 (12) ◽  
pp. 1460-1471 ◽  
Author(s):  
F. HOMBURGER ◽  
N. F. YOUNG ◽  
IRIS FORBES
Keyword(s):  
Gastric Cancer ◽  
Nitrogen Balance ◽  
Blood Stream ◽  
Postoperative Phase ◽  
Tissue Protein ◽  
Positive Nitrogen Balance ◽  
Tissue Protein Synthesis ◽  
High Protein Diets ◽  
Protein Diets

Abstract 1 . The existence of hypoproteinemia in patients with gastric cancer has once again been observed. 2. The intractability of this type of hypoproteinemia in the postoperative phase to treatment with high protein diets and in the presence of positive nitrogen balance has been demonstrated. 3. Long-term studies in two patients, for 28 and 108 days respectively, suggest that the persistence of hypoproteinemia in patients with gastric cancer in positive nitrogen balance is probably not due to a marked degree of depletion of tissue protein stores alone. These patients retained more protein than would have been necessary to replenish depleted tissues. 4. It seems more likely that while such patients are capable of tissue protein synthesis, they fail to shift new protein into the blood stream.

Beneficial effects of low-carbohydrate-high-protein diets in long-term diabetic rats

Metabolism ◽  
1980 ◽  
Vol 29 (5) ◽  
pp. 421-428 ◽  
Author(s):  
Eberhard G. Siegel ◽  
Volker E. Trapp ◽  
Claes B. Wollheim ◽  
Albert E. Renold ◽  
Felix H. Schmidt
Keyword(s):  
Diabetic Rats ◽  
High Protein ◽  
Beneficial Effects ◽  
Low Carbohydrate ◽  
High Protein Diets ◽  
Protein Diets

scholarly journals Differential effects of long-term leucine infusion on tissue protein synthesis in neonatal pigs

Amino Acids ◽  
2010 ◽  
Vol 40 (1) ◽  
pp. 157-165 ◽  
Author(s):  
Fiona A. Wilson ◽  
Agus Suryawan ◽  
Renán A. Orellana ◽  
María C. Gazzaneo ◽  
Hanh V. Nguyen ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Tissue Protein ◽  
Differential Effects ◽  
Neonatal Pigs ◽  
Tissue Protein Synthesis

Effects of Long-Term High-Fat/High-Energy and High-Protein Diets on Insulin and Ghrelin Expression in Developing Rats

2012 ◽  
Vol 37 (3) ◽  
pp. 97-109 ◽  
Author(s):  
Xiumin Wang ◽  
Shaoqing Ni ◽  
Yanping Xu ◽  
Li Liang ◽  
Lizhong Du ◽  
...  
Keyword(s):  
High Energy ◽  
High Protein ◽  
High Fat ◽  
High Protein Diets ◽  
Protein Diets

scholarly journals The Effects of High-Protein Diets on Kidney Health and Longevity

2020 ◽  
Vol 31 (8) ◽  
pp. 1667-1679 ◽  
Author(s):  
Gang-Jee Ko ◽  
Connie M. Rhee ◽  
Kamyar Kalantar-Zadeh ◽  
Shivam Joshi
Keyword(s):  
Dietary Protein ◽  
Protein Intake ◽  
Observational Studies ◽  
Animal Protein ◽  
High Protein ◽  
High Protein Intake ◽  
High Protein Diets ◽  
Protein Diets ◽  
Kidney Health

Although high-protein diets continue to be popular for weight loss and type 2 diabetes, evidence suggests that worsening renal function may occur in individuals with—and perhaps without—impaired kidney function. High dietary protein intake can cause intraglomerular hypertension, which may result in kidney hyperfiltration, glomerular injury, and proteinuria. It is possible that long-term high protein intake may lead to de novo CKD. The quality of dietary protein may also play a role in kidney health. Compared with protein from plant sources, animal protein has been associated with an increased risk of ESKD in several observational studies, including the Singapore Chinese Health Study. Potential mediators of kidney damage from animal protein include dietary acid load, phosphate content, gut microbiome dysbiosis, and resultant inflammation. In light of such findings, adopting current dietary approaches that include a high proportion of protein for weight reduction or glycemic control should be considered with care in those at high risk for kidney disease. Given the possibility of residual confounding within some observational studies and the conflicting evidence from previous trials, long-term studies including those with large sample sizes are warranted to better ascertain the effects of high protein intake on kidney health.

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