The hospital anxiety and depression rating scale: A cross-sectional study of psychometrics and case finding abilities in general practice

AbstractAnxiety and depression in hospitalized COVID-19 patients in Thailand during the first wave of the pandemic were investigated. Thai version of Hospital Anxiety and Depression Scale (HADS) was chosen as an instrument for evaluation. Thirty-two voluntary participants completed the questionnaire. Three (9.4%) respondents had abnormal anxiety sub-scale scores while no respondents had abnormal depression sub-scale scores. There was no statistical demographic difference between the anxiety and non-anxiety groups.

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Anxiety and depression in school-age patients with spinal muscular atrophy: a cross-sectional study

Orphanet Journal of Rare Diseases ◽

10.1186/s13023-021-02008-8 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Mei Yao ◽

Yu Xia ◽

Yijie Feng ◽

Ying Ma ◽

Yi Hong ◽

...

Keyword(s):

Spinal Muscular Atrophy ◽

Rating Scale ◽

Muscular Atrophy ◽

Genetic Diagnosis ◽

Cross Sectional Study ◽

Anxiety And Depression ◽

Type I ◽

School Age ◽

Sectional Study ◽

Cross Sectional

Abstract Background Spinal muscular atrophy (SMA) is a rare neurogenetic disease which involves multisystem dysfunctions such as respiratory, digestive, and motor disorders. Anxiety, depression and other psychological disorders often accompany severe chronic physical diseases. The aim of this study was to investigate the prevalence of anxiety and depression along with their influencing factors among school-age patients with SMA. Methods We conducted a cross-sectional study on school-age SMA patients in China. Patients aged 8–18 years with a genetic diagnosis of 5qSMA were invited to answer a questionnaire composed of sociodemographic and clinical questions, then to complete the Screen for Child Anxiety-Related Emotional Disorders and Depression Self-Rating Scale for depression and anxiety level evaluation. At the end of the questionnaire, further questions assessed the subjective anxiety and subjective depression of patients’ caregivers and their expectations for their child’s future. Results Complete data were available for 155 patients. The sample included 45.8% boys and 54.2% girls; 65.2% were type II, 27.1% were type III, and the remainder were type I SMA. Rates of anxiety and depression in these school-age SMA patients were 40.0% and 25.2%, respectively. Gender, age, and disease type were not associated with anxiety or depression, but respiratory system dysfunction, digestive system dysfunction, skeletal deformity, rehabilitation exercise, academic delay, specialized support from school, household income level, caregivers’ subjective anxiety, and caregivers’ expectations were significantly related to both anxiety and depression. Conclusions There was a high prevalence of anxiety and depression in school-age SMA patients in China. Professional psychological care maybe included in the standard of care. These results also call for possible targets for intervention such as reducing complications, improving drug accessibility, retaining normal schooling, strengthening school support, and enhancing the ability of the caregivers of SMA patients to assist in the diagnosis and treatment of the disease, so improving the mental health of SMA patients.

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Assessment of hospital anxiety and depression in newly diagnosed head and neck cancer patients in cancer institutes — A cross-sectional study

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11i4.3971 ◽

2020 ◽

Vol 11 (4) ◽

pp. 7811-7816

Author(s):

Sushanthi S ◽

Meignana Arumugham Indiran ◽

Pradeep Kumar Rathinavelu ◽

Arthi Balasubramaniam

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Cancer Patients ◽

Neck Cancer ◽

Cross Sectional Study ◽

Anxiety And Depression ◽

Newly Diagnosed ◽

Sectional Study ◽

Hospital Anxiety ◽

Cross Sectional

Individuals often encounter psychological distress after a diagnosis of cancer, especially head and neck cancer (HNC). Worries regarding restricted functions, facial disfigurement, waiting time for investigation and duration of hospital stay for treatment make them feel awful. Often this feeling goes unnoticed and is underestimated. We aimed to assess the prevalence of the dreadful feeling in terms of anxiety and depression in newly diagnosed head and neck cancer patients. A cross-sectional study was conducted in two cancer-treating institutions in South India. About 357 freshly diagnosed HNC patients participated in the study. Pre-validated Hospital Anxiety and Depression Scale (HADS) was used to assess the anxiety and depression levels. Descriptive statistics was done to report socio-demographic, clinical variables and mean scores. Independent t-test and correlation test were done for comparison and association, respectively. Mean depression score for males and females was 11.481, 11.865, respectively. Mean anxiety score for males was 11.708 and 11.792 for females. There was a strong positive correlation between depression and anxiety score (0.864) among patients. There was no statistically significant difference in the mean anxiety and depression scores among gender, socioeconomic status, marital status and cancer stages (p>0.05). Newly diagnosed HNC patients had an abnormal level of anxiety and depression, which needs special attention and care during treatment for a better outcome.

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Association Between Levels of Depression Symptoms and Moderately Increased Levels of the Inflammation Marker Albuminuria Is Explained by Age and Comorbidity.

10.21203/rs.3.rs-1054344/v1 ◽

2021 ◽

Author(s):

Solfrid Romundstad ◽

Torfinn Hynnekleiv

Keyword(s):

Depression Scale ◽

Cross Sectional Study ◽

Health Study ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Sectional Study ◽

Inflammation Marker ◽

Hospital Anxiety ◽

Cross Sectional ◽

Symptoms Of Depression

Abstract Background: The study aimed to examine whether there are associations between levels of depression symptoms and levels of the inflammation marker albuminuria. Materials and methods: The 8303 participants in this cross-sectional study were subjects from the second survey of the Trøndelag Health Study (HUNT, Norway). Depression symptoms were assessed by the Hospital Anxiety and Depression Scale (HADS). Logistic regression analysis was performed to estimate the odds ratio (OR) for moderately increased albuminuria (ACR > 3.0 mg/mmol) according to different HADS subgroups and -scores.Results: Unadjusted ORs for moderately increased albuminuria were significantly increased in those with HADS > 8 (OR 1.27, 95% CI 1.05-1.54, p=0.013) and HADS > 11 (OR 1.59, 95% CI 1.19-2.14, p=0.002). However, after adjusting for age and sex, only HADS > 11 was significantly associated with ACR > 3.0 mg/mmol (OR 1.46, 95% CI 1.08-1.98, p=0.014), and after multivariable adjustments for cardiovascular risk factors and comorbidity, there were no significant associations. Conclusion: The positive and significant association between moderately increased albuminuria and symptoms of depression found in unadjusted analyses weakened and disappeared after adjustments. Although individuals with depressive symptoms had albuminuria more often than individuals without such symptoms, albuminuria may reflect other comorbidity and inflammation conditions than depression.

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Cluster headache and anxiety: Results of the EUROLIGHT cluster headache project – An Internet-based, cross-sectional study of people with cluster headache

Clinical and Translational Neuroscience ◽

10.1177/2514183x20925956 ◽

2020 ◽

Vol 4 (1) ◽

pp. 2514183X2092595

Author(s):

Heiko Pohl ◽

Andreas R Gantenbein ◽

Peter S Sandor ◽

Jean Schoenen ◽

Colette Andrée

Keyword(s):

Cluster Headache ◽

Odds Ratio ◽

Elevated Level ◽

Depression Scale ◽

Cross Sectional Study ◽

Anxiety And Depression ◽

Sectional Study ◽

Hospital Anxiety ◽

Cross Sectional ◽

Anxiety Subscale

Objective: The aim of this study is to evaluate how anxiety influences the burden of disease of cluster headache. Methods: Participants completed a modified version of the EUROLIGHT questionnaire. Anxiety was measured with the anxiety subscale of the Hospital Anxiety and Depression scale. An elevated level of anxiety was assumed when eight or more points were scored. Results: The data of 1089 participants were taken for analysis. The score of the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A) correlated weakly with the number of attacks in the last 30 days ( r = 0.17). A score of eight and above in the HADS-A was associated with hurting oneself during an attack (odds ratio (OR) = 2.63), worrying about future attacks (OR = 2.95) and reporting of both failed relationships (OR = 2.81) and career problems (OR = 2.65). The odds of feeling understood by family and friends as well as colleagues and employers were lower in anxious persons (OR = 0.35 and 0.40, respectively). Conclusions: Anxiety complicates dealing with cluster headache and strongly aggravates its burden. Instead of finding help in others, anxious persons feel misunderstood and withdraw; relationships fail and difficulties at work arise.

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Comorbid insomnia, psychological symptoms and widespread pain among patients suffering from musculoskeletal pain in general practice: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2019-031971 ◽

2019 ◽

Vol 9 (6) ◽

pp. e031971 ◽

Cited By ~ 2

Author(s):

Louise Sørensen ◽

Morten Sig Ager Jensen ◽

Michael Skovdal Rathleff ◽

Sinead Holden

Keyword(s):

General Practice ◽

Depressive Symptoms ◽

Psychological Symptoms ◽

Cross Sectional Study ◽

Anxiety And Depression ◽

Sectional Study ◽

Cross Sectional ◽

Comorbid Insomnia ◽

Modifiable Factors ◽

Secondary Outcomes

ObjectiveThe aim of this study was to examine the association between musculoskeletal (MSK) pain, insomnia, anxiety and depressive symptoms in patients from general practice.DesignThis is a cross-sectional study.SettingThis study was conducted in general practice in Denmark.ParticipantsA consecutive sample of 390 general practice patients (aged 12 years or older) were included; 183 patients with MSK pain and 207 patients without MSK pain. To be included in the MSK pain group, participants with MSK pain were required to report MSK pain at least weekly during the preceding month, which had a negative impact on daily activities.Primary and secondary outcomes measuresThe primary outcome was insomnia evaluated by the Athens Insomnia Scale. The secondary outcomes were psychological symptoms assessed by the Hospital Anxiety and Depression Scale.ResultsPatients with MSK pain had a significantly higher prevalence of insomnia (difference 25.5%, p<0.0001), anxiety (difference 24.3%, p<0.0001) and depressive symptoms (difference 11%, p<0.0001) compared with patients without MSK pain. Furthermore, patients with MSK pain and comorbid insomnia had significantly higher levels of anxiety and symptoms of depression compared with patients with MSK pain without insomnia (p<0.0001). These relationships remained robust when controlling for age, sex and body mass index in linear regression.ConclusionOne in two patients in general practice report MSK pain. Comorbid MSK pain and insomnia are common and are associated with a higher prevalence of anxiety and depression. This highlights the importance of establishing the presence of insomnia and affective disorders as potentially modifiable factors during treatment of MSK pain in general practice.

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A cross-sectional study of agreement between the Hospital Anxiety and Depression Scale and patient- and radiation oncologist-reported single-item assessment of depression and anxiety

Psycho-Oncology ◽

10.1002/pon.4736 ◽

2018 ◽

Vol 27 (7) ◽

pp. 1840-1846 ◽

Cited By ~ 2

Author(s):

Lisa Mackenzie ◽

Mariko Carey ◽

Eiji Suzuki ◽

Michio Yoshimura ◽

Masakazu Toi ◽

...

Keyword(s):

Depression Scale ◽

Cross Sectional Study ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Radiation Oncologist ◽

Sectional Study ◽

Hospital Anxiety ◽

Cross Sectional ◽

Single Item

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Factors associated with anxiety and depression in rheumatoid arthritis patients: a cross-sectional study

10.21203/rs.3.rs-21612/v1 ◽

2020 ◽

Author(s):

Miyabi Uda ◽

Motomu Hashimoto ◽

Ryuji Uozumi ◽

Mie Torii ◽

Takao Fujii ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Disease Activity ◽

Depression Scale ◽

Cross Sectional Study ◽

Anxiety And Depression ◽

Sectional Study ◽

Hospital Anxiety ◽

Cross Sectional ◽

Hospital Anxiety Depression Scale ◽

Anxiety Depression

Abstract Introduction / objectives Management of anxiety and depression in rheumatoid arthritis (RA) patients is vital. Previous studies investigating this topic are conflicting, and this topic still has not been thoroughly investigated. This study aimed to clarify the association of disease activity with anxiety and depression after controlling for physical disability, pain, and treatment. Method We conducted a cross-sectional study of RA patients from the Kyoto University Rheumatoid Arthritis Management Alliance cohort. For assessments, we used the Disease Activity Score (DAS28), Health Assessment Questionnaire Disability Index (HAQ-DI), and Hospital Anxiety Depression Scale. Depression and anxiety were defined by a Hospital Anxiety Depression Scale score ≥8. We then performed multivariable logistic regression analyses. Results Of 517 participants, 17.9% had anxiety, and 28.2% had depression. The multivariable logistic regression analyses showed patients with DAS28-based non-remission had low association with anxiety (odds ratio [OR] [95% confidence interval {CI}], 0.93 [0.48–1.78]: p = 0.82) but slight association with depression (OR [95% CI], 1.45 [0.81–2.61]: p = 0.22). However, severity of the patient’s global assessment (PtGA) on DAS28 was associated with anxiety (OR [95% CI], 1.15 [1.02–1.29]; p = 0.03) and depression (OR [95% CI], 1.21 [1.09–1.35]; p < 0.01). Additionally, HAQ-DI-based non-remission was associated with anxiety (OR [95% CI], 3.51 [1.85–6.64]; p < 0.01) and depression (OR [95% CI], 2.65 [1.56–4.50]; p < 0.01). Younger patients (OR [95% CI], 0.83 [0.68–1.01]; p = 0.07) and patients not treated with methotrexate (OR [95% CI], 0.67 [0.40–1.13]; p = 0.13) tended to suffer from anxiety. Patients using steroids had a closer association with depression than those not using them (OR [95% CI], 1.66 [1.03–2.67]; p = 0.04). Conclusions Assessment of disease activity, PtGA, and HAQ-DI are important for assessing anxiety and depression in RA patients. Attention should be paid to improving PtGA and physical function.

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