Factors associated with return to work of breast cancer survivors: a systematic review

Adjuvant endocrine therapy (AET) reduces risk of breast cancer recurrence. However, suboptimal adherence and persistence to AET remain important clinical issues. Understanding factors associated with adherence may help inform efforts to improve use of AET as prescribed. The present systematic review examined potentially modifiable factors associated with adherence to AET in accordance with PRISMA guidelines (PROSPERO registration ID: CRD42019124200). All studies were included, whether factors were significantly associated with adherence or results were null. This review also accounted for the frequency with which a potentially modifiable factor was examined and whether univariate or multivariate models were used. This review also examined whether methodological or sample characteristics were associated with the likelihood of a factor being associated with AET adherence. A total of 68 articles were included. Potentially modifiable factors were grouped into six categories: side effects, attitudes toward AET, psychological factors, healthcare provider-related factors, sociocultural factors, and general/quality of life factors. Side effects were less likely to be associated with adherence in studies with retrospective or cross-sectional than prospective designs. Self-efficacy (psychological factor) and positive decisional balance (attitude toward AET) were the only potentially modifiable factors examined ≥10 times and associated with adherence or persistence ≥75% of the time in both univariate and multivariate models. Self-efficacy and decisional balance (i.e., weight of pros vs. cons) were the potentially modifiable factors most consistently associated with adherence, and hence may be worth focusing on as targets for interventions to improve AET adherence among breast cancer survivors.

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Factors associated with return to work in breast cancer survivors treated at the Public Cancer Hospital in Brazil

Supportive Care in Cancer ◽

10.1007/s00520-019-05164-7 ◽

2020 ◽

Vol 28 (9) ◽

pp. 4445-4458 ◽

Cited By ~ 2

Author(s):

Isabela Caroline Freitas Colombino ◽

Almir José Sarri ◽

Isabela Queiros Castro ◽

Carlos Eduardo Paiva ◽

René Aloisio da Costa Vieira

Keyword(s):

Breast Cancer ◽

Return To Work ◽

Cancer Survivors ◽

Breast Cancer Survivors ◽

The Public ◽

Factors Associated ◽

Cancer Hospital

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FACTORS ASSOCIATED WITH RETURN TO WORK OF BREAST CANCER SURVIVORS TREATED AT THE PUBLIC CANCER HOSPITAL IN BRAZIL

10.29289/259453942019v29s1g14 ◽

2019 ◽

Author(s):

Isabela C. F. Colombino ◽

◽

Fabiola C. B. Silva ◽

Jonathas J. Silva ◽

Idam Oliveira- Junior ◽

...

Keyword(s):

Breast Cancer ◽

Return To Work ◽

Cancer Survivors ◽

Breast Cancer Survivors ◽

The Public ◽

Factors Associated ◽

Cancer Hospital

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Functionality and factors associated with work behaviour among Brazilian breast cancer survivors: A cross-sectional study

Work ◽

10.3233/wor-203342 ◽

2020 ◽

Vol 67 (4) ◽

pp. 917-925

Author(s):

Kamilla Zomkowski ◽

Anke Bergmann ◽

Cinara Sacomori ◽

Mirella Dias ◽

Fabiana Flores Sperandio

Keyword(s):

Breast Cancer ◽

Return To Work ◽

Cancer Survivors ◽

Breast Cancer Survivors ◽

Cross Sectional Study ◽

Upper Limbs ◽

Sectional Study ◽

Cross Sectional ◽

Factors Associated ◽

Returning To Work

BACKGROUND: Breast cancer treatments lead to several comorbidities in the upper limbs, such as pain and stiffness, hindering physical functions and the return to work. OBJECTIVE: To explore the functionality and factors associated with work behaviour among manual and non-manual Brazilian workers who have recovered from breast cancer. METHODS: This is an observational cross-sectional study involving Brazilian breast cancer survivors. The sociodemographic, work, and clinical aspects were assessed through clinical records, upper limb disability, and human functionality obtained from 62 women. Multiple and univariate logistic regressions were used to identify the association of variables on return to work, p < 0.05. RESULTS: 56.5% of women did not return to work, the mean time for returning to work was 16 months (±15.21), absenteeism from work lasted 41 months (±34.58). Modified radical mastectomy (OR = 5.13, 95% CI = 1.35 to 18.66) and moderate-to-severe disability levels in the upper limbs (OR = 6.77, 95% CI = 1.86 to 24.92) were associated with not returning to work. The loss of productivity was higher among non-manual workers (21.5%) (p = 0.040). CONCLUSIONS: The rates of not returning to work after breast cancer treatment are high. Women who did not return to work presented higher levels of disability.

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Return to work of breast cancer survivors: a systematic review of intervention studies

BMC Cancer ◽

10.1186/1471-2407-9-117 ◽

2009 ◽

Vol 9 (1) ◽

Cited By ~ 76

Author(s):

JL Hoving ◽

MLA Broekhuizen ◽

MHW Frings-Dresen

Keyword(s):

Breast Cancer ◽

Systematic Review ◽

Return To Work ◽

Cancer Survivors ◽

Breast Cancer Survivors ◽

Intervention Studies

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145P The potential benefits of internet-based cognitive behavioural therapy for improving psychosocial aspects, sexual functioning, and treatment-induced menopausal symptoms among breast cancer survivors: Systematic review and meta-analysis

Annals of Oncology ◽

10.1016/j.annonc.2021.03.159 ◽

2021 ◽

Vol 32 ◽

pp. S83

Author(s):

B.P. Putra ◽

F.N. Putra

Keyword(s):

Breast Cancer ◽

Systematic Review ◽

Cancer Survivors ◽

Cognitive Behavioural Therapy ◽

Sexual Functioning ◽

Breast Cancer Survivors ◽

Meta Analysis ◽

Behavioural Therapy ◽

Cognitive Behavioural ◽

Potential Benefits

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Updated systematic review of exercise studies in breast cancer survivors: attention to the principles of exercise training

British Journal of Sports Medicine ◽

10.1136/bjsports-2017-098389 ◽

2017 ◽

Vol 53 (8) ◽

pp. 504-512 ◽

Cited By ~ 31

Author(s):

Sarah E Neil-Sztramko ◽

Kerri M Winters-Stone ◽

Kelcey A Bland ◽

Kristin L Campbell

Keyword(s):

Breast Cancer ◽

Systematic Review ◽

Exercise Training ◽

Cancer Survivors ◽

Randomised Controlled Trials ◽

Breast Cancer Survivors ◽

Exercise Prescription ◽

Controlled Trials ◽

Exercise Interventions ◽

Randomised Controlled

ObjectivesTo update our previous evaluation of the exercise interventions used in randomised controlled trials of breast cancer survivors in relation to (1) the application of the principles of exercise training in the exercise prescription; (2) the reporting of the components of the exercise prescription; and (3) the reporting of adherence of participants to the prescribed interventions.DesignSystematic review.Data sourcesThe OVID Medline, Embase, CINAHL and SPORTDiscus electronic databases were searched from January 2010 to January 2017.Eligibility criteriaRandomised controlled trials of at least 4 weeks of aerobic and/or resistance exercise in women diagnosed with breast cancer, reporting on physical fitness or body composition outcomes.ResultsSpecificity was appropriately applied by 84%, progression by 29%, overload by 38% and initial values by 67% of newly identified studies. Reversibility was reported by 3% anddiminishing returns by 22% of newly identified studies. No studies reported all components of the exercise prescription in the methods, or adherence to the prescribed intervention in the results. Reporting of reversibility has increased from 2010, but no other improvements in reporting were noted from the previous review.Summary/ConclusionNo studies of exercise in women with breast cancer attended to all principles of exercise training, or reported all components of the exercise prescription in the methods, or adherence to the prescription in the results. Full reporting of the exercise prescribed and completed is essential for study replication in research and translating research findings into the community, and should be prioritised in future trials.

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