scholarly journals Plasma levels of the arterial wall protein fibulin-1 are associated with carotid-femoral pulse wave velocity: a cross-sectional study

2013 ◽  
Vol 12 (1) ◽  
pp. 107 ◽  
Author(s):  
Esben Laugesen ◽  
Pernille Høyem ◽  
Jens Christiansen ◽  
Søren Knudsen ◽  
Klavs Hansen ◽  
...  
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Plasma Levels ◽  
Arterial Wall ◽  
Pulse Wave ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Telomere Length and Arterial Stiffness Reflected by Brachial–Ankle Pulse Wave Velocity: A Population-Based Cross-Sectional Study

2021 ◽  
Vol 11 (12) ◽  
pp. 1278
Author(s):  
Kyi Mar Wai ◽  
Sawada Kaori ◽  
Ken Itoh ◽  
Okuyama Shinya ◽  
Yuka Uchikawa ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Tail Length ◽  
Population Based ◽  
Cross Sectional Study ◽  
Biological Aging ◽  
Sectional Study ◽  
Cross Sectional

Telomere (TL) is a biomarker of biological aging, and its shortening is associated with major risk factors for cardiovascular diseases (CVD). This study aimed to identify whether TL is associated with arterial stiffness as reflected by brachial–ankle pulse wave velocity (baPWV). This population-based cross-sectional study involved 1065 individuals in the Iwaki area, Japan. Total TL length and TL G-tail length were measured by hybridization protection assay. The baPWV was measured on the right and left sides using a non-invasive vascular screening device. The associations between TL and baPWV were assessed by multivariate linear regression. Compared with the shortest total TL tertile, the longest total TL group showed a significant decrease in baPWV (lowest vs. highest tertile: adjusted beta: −41.24, 95% confidence interval (CI): −76.81, −5.68). The mean baPWV decreased with a longer TL (TL G-tail length: p trend < 0.001, total TL: p trend < 0.001). TL G-tail and total TL lengths were inversely associated with baPWV, implicating TL shortening in the development of CVD. This study provides evidence of the factors influencing CVD risks at a very early stage when individuals can still take necessary precautions before CVD gives rise to a symptomatic health outcome.

scholarly journals Intraocular pressure predicts premature coronary atherosclerosis

2020 ◽  
Vol 66 (12) ◽  
pp. 1707-1711
Author(s):  
Mehmet Kaplan ◽  
Ozge Ozcan Abacýoglu ◽  
Fethi Yavuz ◽  
Gizem Ilgýn Kaplan ◽  
Betül Düzen ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Cross Sectional Study ◽  
Control Group ◽  
Biochemical Tests ◽  
Cross Sectional ◽  
Significant Difference ◽  
Artery Disease

SUMMARY OBJECTIVE: The aim of this study was to investigate the association between intraocular pressure (IOP) and premature atherosclerotic coronary artery disease (PACAD) by comparing central corneal thicknesses (CCTs) measurements. METHODS: One hundred-eighty-six subjects were enrolled in this cross-sectional study, 100 in the PACAD group and 86 in the control group. All participants underwent a physical examination and routine biochemical tests. Ophthalmological examinations, including IOP and CCTs measurements, were performed for each subject. Additionally, pulse wave velocity measurements were obtained and recorded. RESULTS: Participants with PACAD showed significantly higher IOP values than those without atherosclerosis (p = 0.001), and there was no statistically significant difference between the groups in terms of CCT (p = 0.343). Also, pulse wave velocity (PWV) values were statistically significantly higher in the PACAD group (p = 0.001). High IOP was not significantly associated with metabolic syndrome parameters (p > 0.05). CONCLUSIONS: A relationship was found between PACAD and IOP, but CCTs were not associated with PACAD. The IOP measurement is affected by CCT; therefore, CCT is used to correct IOP values. To our knowledge, this is the first study to report a positive relationship between PACAD and IOP based on CCTs measurements.

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