scholarly journals The effects of a muscle resistance program on the functional capacity, knee extensor muscle strength and plasma levels of IL-6 and TNF-α in pre-frail elderly women: a randomized crossover clinical trial - a study protocol

Trials ◽  
2010 ◽  
Vol 11 (1) ◽  
Author(s):  
Lygia P Lustosa ◽  
Fernanda M Coelho ◽  
Juscelio P Silva ◽  
Daniele S Pereira ◽  
Adriana N Parentoni ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Muscle Strength ◽  
Study Protocol ◽  
Functional Capacity ◽  
Frail Elderly ◽  
Plasma Levels ◽  
Elderly Women ◽  
Knee Extensor ◽  
Tnf Α ◽  
Knee Extensor Muscle Strength

scholarly journals Telerehabilitation Intervention in Patients with COVID-19 after Hospital Discharge to Improve Functional Capacity and Quality of Life. Study Protocol for a Multicenter Randomized Clinical Trial

2021 ◽  
Vol 18 (6) ◽  
pp. 2924
Author(s):  
José-Manuel Pastora-Bernal ◽  
María-José Estebanez-Pérez ◽  
Guadalupe Molina-Torres ◽  
Francisco-José García-López ◽  
Raquel Sobrino-Sánchez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Hospital Discharge ◽  
Study Protocol ◽  
Functional Capacity ◽  
Treatment Method ◽  
Current Evidence ◽  
Current Standard

COVID-19 can cause important sequels in the respiratory system and frequently presents loss of strength, dyspnea, polyneuropathies and multi-organic affectation. Physiotherapy interventions acquire a fundamental role in the recovery of the functions and the quality of life. Regarding the recovery phases after hospital discharge, the current evidence available is very preliminary. Telerehabilitation is presented as a promising complementary treatment method to standard physiotherapy. The main objective of this research is to evaluate the effectiveness of a personalized telerehabilitation intervention after discharge from hospital for the improvement of functional capacity and quality of life compared to a program of health education and/or care in a rehabilitation center. As secondary objectives, to identify the satisfaction and perception of patients with the telerehabilitation intervention and the presence of barriers to its implementation, as well as to evaluate the cost-effectiveness from the perspective of the health system. This study protocol will be carried out through a single blind multicenter randomized clinical trial in the south of Spain. We hypothesize that the implementation of a telerehabilitation program presents results not inferior to those obtained with the current standard intervention. If the hypothesis is confirmed, it would be an opportunity to define new policies and interventions to address this disease and its consequences. Trial registration NCT04742946.

scholarly journals Knee Extensor Muscle Strength And The Depressive Status Among Older Japanese Women: A Cross-sectional Study

2021 ◽  
Vol 53 (8S) ◽  
pp. 196-197
Author(s):  
Ohta Takahisa ◽  
Hiroyuki Sasai ◽  
Narumi Kojima ◽  
Yosuke Osuka ◽  
Kiyoji Tanaka ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Knee Extensor ◽  
Cross Sectional Study ◽  
Japanese Women ◽  
Extensor Muscle ◽  
Sectional Study ◽  
Cross Sectional ◽  
Knee Extensor Muscle Strength

scholarly journals Muscle strength but not functional capacity is associated with plasma interleukin-6 levels of community-dwelling elderly women

2008 ◽  
Vol 41 (12) ◽  
pp. 1148-1153 ◽  
Author(s):  
D.M.G. Oliveira ◽  
F.M.S. Narciso ◽  
M.L.A.S. Santos ◽  
D.S. Pereira ◽  
F.M. Coelho ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Functional Capacity ◽  
Interleukin 6 ◽  
Elderly Women ◽  
Community Dwelling

scholarly journals Effects of resistance training on self-reported disability in older adults with functional limitations or disability – a systematic review and meta-analysis

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Pia Øllgaard Olsen ◽  
Anne-Ditte Termannsen ◽  
Maja Bramming ◽  
Mark A. Tully ◽  
Paolo Caserotti
Keyword(s):  
Older Adults ◽  
Resistance Training ◽  
Muscle Strength ◽  
Functional Capacity ◽  
Meta Analysis ◽  
Functional Limitations ◽  
Knee Extensor ◽  
Objective Measures ◽  
Lower Body ◽  
Positive Effect

Abstract Background Self-reported disability has a strong negative impact on older people’s quality of life and is often associated with the need for assistance and health care services. Resistance training (RT) has been repeatedly shown to improve muscle function (e.g. strength) and functional capacity (e.g. gait speed, chair-rise) in older adults with functional limitations. Nevertheless, it is unclear whether such objectively assessed improvements translate into a reduction in self-reported disability. Objectives To assess: i) whether and to what extent RT interventions have an effect on self-reported disability in older adults (≥65 years) with functional limitations or disability; and ii) whether the effects on self-reported disability are associated with changes in objective measures of muscle strength and functional capacity across studies. Methods PubMed, Embase, Web of Science, CINAHL and SPORTDiscus electronic databases were searched in June 2018. Randomized controlled trials reporting effects of RT on self-reported disability/function in ≥65 year-old adults with defined, functional limitations or self-reported disability were eligible. Data on self-reported disability/function were pooled by calculating adjusted standardized mean differences (SMD) using Hedges’g. Likewise, effect sizes for three secondary outcomes: knee extensor muscle strength; gait capacity; and lower body functional capacity were calculated and fit as covariates in separate meta-regressions with self-reported disability as the dependent factor. Results Fourteen RCTs were eligible for the primary meta-analysis on self-reported disability. The total number of participants was 651 (intervention n = 354; control n = 297). A significant moderate positive effect of RT was found (SMD: 0.59, 95% CI: 0.253 to 0.925, p = 0.001). Between-study heterogeneity was present (I2 statistic = 75,1%, p <  0.001). RT effects on objective measures of lower body functional capacity were significantly associated with effects on self-reported disability (Adj. R2 = 99%, p = 0.002, n = 12 studies), whereas no significant associations with gait capacity or knee extensor strength were found. Conclusions This review provides evidence that RT has a moderate positive effect on self-reported disability/function in old people with or at risk for disability. The effects are strongly associated with effects on objective measures of lower body functional capacity.

scholarly journals Athletic training affects the uniformity of muscle and tendon adaptation during adolescence

2016 ◽  
Vol 121 (4) ◽  
pp. 893-899 ◽  
Author(s):  
Falk Mersmann ◽  
Sebastian Bohm ◽  
Arno Schroll ◽  
Robert Marzilger ◽  
Adamantios Arampatzis
Keyword(s):  
Mechanical Properties ◽  
Muscle Strength ◽  
Athletic Training ◽  
Time Course ◽  
Knee Extensor ◽  
Tendon Injury ◽  
Increased Risk ◽  
Tendon Adaptation ◽  
Tendon Force ◽  
Knee Extensor Muscle Strength

With the double stimulus of mechanical loading and maturation acting on the muscle-tendon unit, adolescent athletes might be at increased risk of developing imbalances of muscle strength and tendon mechanical properties. This longitudinal study aims to provide detailed information on how athletic training affects the time course of muscle-tendon adaptation during adolescence. In 12 adolescent elite athletes (A) and 8 similar-aged controls (C), knee extensor muscle strength and patellar tendon mechanical properties were measured over 1 yr in 3-mo intervals. A linear mixed-effects model was used to analyze time-dependent changes and the residuals of the model to quantify fluctuations over time. The cosine similarity (CS) served as a measure of uniformity of the relative changes of tendon force and stiffness. Muscle strength and tendon stiffness increased significantly in both groups ( P < 0.01). However, the fluctuations of muscle strength were greater [A, 17 ± 7 (SD) N·m; C, 6 ± 2 N·m; P < 0.05] and the uniformity of changes of tendon force and stiffness was lower in athletes (CS A, −0.02 ± 0.5; C, 0.5 ± 0.4; P < 0.05). Further, athletes demonstrated greater maximum tendon strain (A, 7.6 ± 1.7%; C, 5.5 ± 0.9%; P < 0.05) and strain fluctuations (A, 0.9 ± 0.4; C, 0.3 ± 0.1; P < 0.05). We conclude that athletic training in adolescence affects the uniformity of muscle and tendon adaptation, which increases the demand on the tendon with potential implications for tendon injury.

scholarly journals Relationship between Serum Vitamin D and Leg Strength in Older Adults with Pre-Dialysis Chronic Kidney Disease: A Preliminary Study

2020 ◽  
Vol 17 (4) ◽  
pp. 1433
Author(s):  
Akira Saito ◽  
Koji Hiraki ◽  
Yuhei Otobe ◽  
Kazuhiro P. Izawa ◽  
Tsutomu Sakurada ◽  
...  
Keyword(s):  
Older Adults ◽  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Muscle Strength ◽  
Lower Extremity ◽  
Knee Extensor ◽  
Active Vitamin ◽  
Active Vitamin D ◽  
Lower Extremity Muscle ◽  
Knee Extensor Muscle Strength

Active vitamin D (calcitriol, or 1.25 (OH) 2 D) is associated with muscle weakness, falls, and fracture in community-dwelling older people. This study aimed to investigate the relationship between a serum active vitamin D level and lower extremity muscle strength in elderly patients with pre-dialysis chronic kidney disease (CKD). This cross-sectional study included 231 patients with CKD treated conservatively as outpatients. We analyzed patient background factors, including age, sex, body mass index (BMI), intact parathyroid hormone (PTH), phosphorus, calcium, albumin, serum calcitriol level as an indicator of active vitamin D, and estimated glomerular filtration rate (eGFR) collected from medical records. As an index of lower extremity muscle strength, the isometric knee extension muscle strength-to-weight ratio (kgf/kg) was calculated. The mean patient age was 75.9 ± 6.1 years (68.8% male), and the BMI was 24.1 ± 3.8 kg/m2. A significant correlation was observed between knee extensor muscle strength and serum calcitriol level (r = 0.32, p < 0.01), age (r = –0.30, p < 0.01), BMI (r = −0.31, p < 0.01), intact PTH (r = −0.22, p < 0.01), phosphorus (r = −0.29, p < 0.01), albumin (r = −0.28, p < 0.01), and eGFR (r = 0.25, p < 0.01). Multiple regression analysis showed calcitriol to be significantly associated with knee extensor muscle strength (β: 0.14, 95% confidence interval: 0–0.002, p = 0.04) after adjustment for covariates. These results suggest that the serum active vitamin D level is associated with lower extremity muscle strength in older adults with pre-dialysis CKD. It is necessary to verify whether vitamin D supplementation increases lower extremity muscle strength in pre-dialysis CKD patients.

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