scholarly journals Environmental and occupational respiratory diseases – 1055. CD23, TH1/TH2 cytokines in children with bronchial asthma, bronchiolitis and bronchial pneumonia

2013 ◽  
Vol 6 ◽  
pp. P53
Author(s):  
Anchoju Vijayendra Chary
Keyword(s):  
Bronchial Asthma ◽  
Respiratory Diseases ◽  
Th2 Cytokines

scholarly journals Thyme oil alleviates Ova-induced bronchial asthma through modulating Th2 cytokines, IgE, TSLP and ROS

2021 ◽  
Vol 140 ◽  
pp. 111726
Author(s):  
Ayman M. Mousa ◽  
Ahmad Almatroudi ◽  
Ameen S. Alwashmi ◽  
Waleed Al Abdulmonem ◽  
Abdullah S.M. Aljohani ◽  
...  
Keyword(s):  
Bronchial Asthma ◽  
Th2 Cytokines ◽  
Thyme Oil

New opportunities of halotherapy in the prevention and medical rehabilitation of children

2021 ◽  
pp. 37-47
Author(s):  
Alina Vyacheslavovna Chervinskaya ◽  
Irena Vladimirovna Pogonchenkova ◽  
Maya Alekseevna Khan ◽  
Natalya Anatolievna Mikitchenko ◽  
Natalya Anatolievna Lyan
Keyword(s):  
Sodium Chloride ◽  
Bronchial Asthma ◽  
Respiratory Diseases ◽  
High Efficiency ◽  
Medical Rehabilitation ◽  
Favorable Effect ◽  
Group Method ◽  
Biophysical Properties ◽  
Pediatric Practice ◽  
Highly Dispersed

The article is devoted to new possibilities of using halotherapy in the prevention, treatment and medical rehabilitation of children. In recent years, active work has been carried out to develop new effective methods of reproducing the aerodispersed medium in the form of haloingalation therapy or by group method — in the conditions of a halochamber. The therapeutic effect of halotherapy is determined by the biophysical properties of a dry highly dispersed aerosol of sodium chloride. The paper presents the biophysical properties of the main active factor of halotherapy, i.e. a dry highly dispersed aerosol of sodium chloride, and reveals some aspects of the formation of the mechanism of therapeutic action. The anti-inflammatory, draining, mucolytic, immunomodulatory, sanogenetic effect of haloaerosol is shown. In pediatric practice, haloaerosol therapy is used for medical rehabilitation of children with respiratory diseases (bronchial asthma, bronchitis), ENT pathology (rhinosinusitis, tonsillitis, pharyngitis), skin diseases. Halotherapy is the method of choice in the prevention of acute respiratory diseases and improving the health of children in general education institutions. The high efficiency of the complex application of halotherapy in various diseases in children has been established. A promising direction for the development of halotherapy is the development of combined exposure technologies. The high efficiency of the use of haloingalation therapy in combination with magnetic therapy in the treatment of acute rhinosinusitis in children has been proven. Based on the conducted studies, a favorable effect of the use of halotherapy and flutter therapy on clinical and functional parameters in children with bronchial asthma was revealed. The data on the possibility of combined use of halotherapy with a pulsed low-frequency electrostatic field in the medical rehabilitation of children suffering from bronchial asthma are presented. Simplicity, safety, the possibility of personalization of exposure and good tolerability by children expands the possibilities for using halotherapy in pediatric practice.

A strategy for improvement in diagnosis and treatment of bronchial asthma in primary care

2019 ◽  
Vol 29 (4) ◽  
pp. 457-467
Author(s):  
S. N. Avdeev ◽  
S. R. Aisanov ◽  
A. S. Belevskiy ◽  
A. V. Emel’yanov ◽  
O. M. Kurbacheva ◽  
...  
Keyword(s):  
Primary Care ◽  
Bronchial Asthma ◽  
Primary Care Physicians ◽  
Respiratory Symptoms ◽  
Respiratory Diseases ◽  
Diagnosis And Treatment ◽  
Diagnostic Tools ◽  
Chronic Obstructive ◽  
Asthma Diagnosis ◽  
Chronic Respiratory Diseases

Recently, bronchial asthma is considered as a heterogeneous disease characterized by chronic airway inflammation and respiratory symptoms, which vary in time and intensity and manifest together with variable obstruction of the airways. Asthma is one of the most common chronic respiratory diseases in primary care. Patients with certain respiratory symptoms seek for medical aid initially in primary care physicians, such as therapeutists, general practitioners, and family physicians, who can suspect and diagnose chronic respiratory diseases such as bronchial asthma, chronic obstructive pulmonary disease (COPD), allergic rhinitis, etc. Currently, untimely diagnosis of asthma and late initiation of anti-inflammatory treatment are widespread, mainly due to insufficient knowledge of primary care physicians on diagnostic criteria and therapeutic standards for asthma. Feasible and convenient algorithms for asthma diagnosis and treatment in primary care were developed by experts of Russian Respiratory Society and Russian Association of Allergologists and Clinical Immunologists. A therapeutic algorithm for asthma treatment in primary care institutions uses an approach considering symptom severity both in patients with newly diagnosed and previously treated for asthma. Diagnostic tools, such as a questionnaire for asthma diagnosis and an algorithm for differential diagnosis between asthma and COPD are mainly intended to facilitate diagnosis of chronic respiratory disease, particularly bronchial asthma, by a primary care physician and to improve the healthcare quality for these patients.

Autacoids in sputum in cases of bronchial asthma and other respiratory diseases

1970 ◽  
Vol 22 (7) ◽  
pp. 531-531
Author(s):  
P. Sen ◽  
Anjana Banerjee ◽  
Saroj Gupta ◽  
G. D. Gupta ◽  
R. K. Sanyal
Keyword(s):  
Bronchial Asthma ◽  
Respiratory Diseases

Involvement of GATA-3-dependent Th2 lymphocyte activation in airway hyperresponsiveness

2006 ◽  
Vol 290 (6) ◽  
pp. L1045-L1051 ◽  
Author(s):  
Naomi Yamashita ◽  
Hiroyuki Tashimo ◽  
Hirofumi Ishida ◽  
Yukiko Matsuo ◽  
Hidekazu Tamauchi ◽  
...  
Keyword(s):  
T Cells ◽  
T Lymphocytes ◽  
Bronchial Asthma ◽  
Airway Hyperresponsiveness ◽  
Receptor Gene ◽  
Whole Body ◽  
Th2 Cytokines ◽  
Lipoxygenase Inhibitor ◽  
Airway Responses

The pathophysiological characteristics of bronchial asthma consist of chronic inflammation of airways, airway hyperresponsiveness, and bronchoconstriction. Studies have shown that T helper type 2 (Th2) cytokines produced by both T cells and mast cells in the airway contribute substantially to the initiation of inflammation in both experimental and human bronchial asthma. GATA-3 is a transcription factor essential to the production of Th2 cytokines by T lymphocytes. To clarify the role of GATA-3-expressing T cells in the pathophysiology of bronchial asthma, we utilized transgenic (Tg) mice carrying the GATA-3 gene and the ovalbumin (OVA)-specific T cell receptor gene (GATA-3-Tg/OVA-Tg). Mice were intranasally administrated OVA without systemic immunization. Airway responses were analyzed with noninvasive and invasive whole body plethysmographs. GATA-3-Tg/OVA-Tg mice exhibited significantly higher IL-13 and IL-4 protein expression in the airway. Although there were no differences in the types of infiltrating cells between GATA-3-Tg/OVA-Tg and GATA-3-non-Tg/OVA-Tg mice and no significant increase in IgE level in either group compared with nontreated mice, the response after ACh inhalation was significantly elevated in GATA-3-Tg/OVA-Tg on the seventh day of intranasal treatment with OVA. This hyperresponsiveness was inhibited by 5-lipoxygenase inhibitor and IL-13 neutralization, suggesting that airway responses were induced through IL-13 and leukotriene pathway. In conclusion, airway hyperresponsiveness, a characteristic of bronchial asthma, is regulated at the level of GATA-3 transcription by T lymphocytes in vivo.

scholarly journals Patterns of medicine use in patients of common respiratory diseases treated in the Department of Pediatrics of BSMMU Hospital

2015 ◽  
Vol 30 (2) ◽  
pp. 9-13
Author(s):  
Swarmita Afreen ◽  
Md Sayedur Rahman
Keyword(s):  
Bronchial Asthma ◽  
Respiratory Diseases ◽  
Cross Sectional Study ◽  
Medicine Use ◽  
Cross Sectional ◽  
Patient Profile ◽  
Comprehensive Method ◽  
Oral Steroids ◽  
Generic Prescribing ◽  
Medical University

The present study had attempted to evaluate the medicine use pattern in selected respiratory diseases treated in the Department of Pediatrics of Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital. An observational cross sectional study was conducted in the department of Pediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU) between January 2012 to June 2013. Retrospective prescribing data of sixty cases of bronchiolitis and childhood pneumonia and thirty cases of bronchial asthma was collected from the Record Room and reviewed for inclusion. Then the included treatment records were reviewed and appraised thoroughly. Information regarding patient profile, clinical diagnosis and detail information about medicine was documented in an audit form. Average number of medicine was 3.84, 4.31 and 4.47 in bronchial asthma, bronciholitis and pneumonia respectively and 4.28 for respiratory diseases. Generic prescribing was 12.46% for department of Pediatrics. Antimicrobials were used in 90.00, 96.66 and 100.00 percent cases of bronchial asthma, bronchiloitis and pneumonia respectively. In case of pneumonia, highest prescribed antimicrobial was Ceftriaxone. Intravenous and oral steroids were used in 63.33, 26.66 and 0.00 percent cases of bronchial asthma, bronchiloitis and pneumonia respectively. Wide variation was observed with medicine selection in different respiratory diseases treated in the department of Pediatrics of BSMMU. Appropriateness of prescribing cannot be ascertained by medicine use study only. It was revealed that lots of diversity was present in the treatment or selection of medicine. Detail study using newer and comprehensive method and indicators may provide better understanding about prescribing, which might be beneficial to formulate interventions. DOI: http://dx.doi.org/10.3329/bjpp.v30i2.22676 Bangladesh J Physiol Pharmacol 2014; 30(2):9-13

THE ALLERGEN-PROOF CHAMBER IN THE TREATMENT OF BRONCHIAL ASTHMA AND OTHER RESPIRATORY DISEASES.

The Lancet ◽  
1927 ◽  
Vol 209 (5416) ◽  
pp. 1287-1289 ◽  
Author(s):  
W.Storm Van Leeuwen ◽  
W. Einthoven ◽  
W. Kremer
Keyword(s):  
Bronchial Asthma ◽  
Respiratory Diseases

scholarly journals A CRITICAL REVIEW: TAMAKA SHWASA (BRONCHIAL ASTHMA)

2019 ◽  
Vol 7 (8) ◽  
pp. 258-264
Author(s):  
Vaishnavi Narhari Saka
Keyword(s):  
Bronchial Asthma ◽  
Health Problem ◽  
Respiratory Diseases ◽  
Respiratory Infections ◽  
Climatic Changes ◽  
Chronic Inflammatory Disease ◽  
Age Group ◽  
Major Health Problem ◽  
Major Health ◽  
Recurrent Respiratory Infections

Out of most morbid disorders, the disease shwas is also becoming a major health problem of the society. Difficulties in breathing, cough are common health complains which everyone experiences throughout their life with different magnitude. Such complains are found in every age group. Dyspnea due to respiratory diseases comes under ShwasaRoga. Maha- Urdhva-Chinna-Tamaka and Kshudra are the types of ShwasaRoga. Bronchial asthma is a chronic inflammatory disease of airways characterized by cough, difficulty in breathing and wheeze. Exposure to dust, smoke, recurrent respiratory infections and climatic changes are chief triggering factors of this disease. Bronchial asthma and its associated features clinically correspond to the Tamaka Shwasa described in Ayurveda.

scholarly journals Pattern of Respiratory Diseases among Admitted Children in Pediatric Pulmonology Unit : A Tertiary Center Experiences

2018 ◽  
Vol 9 (2) ◽  
pp. 308-310
Author(s):  
Jotsna Ara Begum ◽  
Mohammad Abdullah Al Mamun ◽  
Akhand Tanzih Sultana ◽  
Md Kamruzzaman ◽  
AFM Ashik Imran ◽  
...  
Keyword(s):  
Bronchial Asthma ◽  
Respiratory Diseases ◽  
Tertiary Care ◽  
Respiratory Illness ◽  
Acute Bronchiolitis ◽  
Acute Respiratory Illness ◽  
Late Autumn ◽  
Medical College ◽  
Tertiary Center ◽  
Pediatric Pulmonology

Background :_The spectrum of respiratory illness is wide and includes diseases of upper and lower airways, communicable and non-communicable types. The variation in pattern of morbidity mortality of respiratory illness may be affected by different environmental and climatic variation in different parts of the world.Objective : The present study intended to explore the pattern of respiratory illnesses seen in Bangladeshi children admitted with respiratory illnesses.Methods :_The present prospective observational study was conducted in children up to 12 years of age admitted with acute respiratory illness in pulmonology unit of Dhaka Shishu (Children) Hospitalfrom July 2012 to July 2013. All children between the age limit with acute respiratory illness were included in the study. A standardized questionnaire was formulated and pretested. Then the data were collected through interview by using the questionnaire. Data were analyzed using SPSS version 17.Results : Total 1169 patients were admitted under pulmonology unit during July 2012 to June 2013 among them 324(27.7%) were admitted with respiratory diseases. Among the respiratory diseases Pneumonia (71.2%), Acute Bronchiolitis (20.1%), Bronchial Asthma (4.2%) and TB (2.7%) were commonest. Bronchopneumonia, Acute Bronchiolitis, Bronchial Asthma and TB was common among under 5 children and less common after 5 years. Male were predominate in every cases. Majority of respiratory cases were belonged to poor socioeconomic status. Pneumonia (50.7%) and Acute Bronchiolitis (58.5%) cases were found during autumn and late autumn. Asthma was common during late autumn and winter and Tuberculosis was common throughout the year. Mortality was higher among pneumonia cases.Conclusions :_Respiratory illness contributes most common cause of admission in tertiary care pediatric hospital. Bronchopneumonia is still the commonest respiratory disease with leading cause of mortality.Northern International Medical College Journal Vol.9(2) Jan 2018: 308-310

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