Hypohydration per se affects mood states and executive cognitive processing: results from a face-valid model for studying some consequences of 'voluntary dehydration'

Abstract The distribution of attention between competing processing demands can have dramatic real-world consequences, however little is known about how limited attentional resources are distributed during real-world behaviour. Here we employ mobile EEG to characterise the allocation of attention across multiple sensory-cognitive processing demands during naturalistic movement. We used a neural marker of attention, the Event-Related Potential (ERP) P300 effect, to show that attention to targets is reduced when human participants walk compared to when they stand still. In a second experiment, we show that this reduction in attention is not caused by the act of walking per se. A third experiment identified the independent processing demands driving reduced attention to target stimuli during motion. ERP data reveals that the reduction in attention seen during walking reflects the linear and additive sum of the processing demands produced by visual and inertial stimulation. The mobile cognition approach used here shows how limited resources are precisely re-allocated according to the sensory processing demands that occur during real-world behaviour.

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Locus of the Information Familiarity Effect in the Search of Computer Menus

Proceedings of the Human Factors Society Annual Meeting ◽

10.1177/154193128302700917 ◽

1983 ◽

Vol 27 (9) ◽

pp. 826-830 ◽

Cited By ~ 10

Author(s):

Benjamin L. Somberg ◽

Maria C. Picardi

Keyword(s):

Cognitive Processing ◽

Causative Agent ◽

Response Latency ◽

Empirical Validation ◽

Familiarity Effect ◽

Correct Item ◽

Overall Response ◽

Scan Rate ◽

Per Se

Preliminary empirical findings (Somberg, Boggs, & Picardi, 1982) concerning the search of computer menus indicated that one's familiarity with the information being sought had an effect on the speed with which the correct item was selected from the menu, but did not influence the scan rate per se. Results from three experiments which attempted to determine the locus of that effect are presented here. It was hypothesized that the familiarity of the desired information has an effect on either (1) the time needed to activate the category that described the information or (2) the time needed to confirm that a selected item was the correct one. As neither hypothesis received empirical validation, it was determined that the accuracy, rather than the duration, of the category activation stage is the causative agent. Category activation errors, which are more frequent when the desired information is unfamiliar, necessitate additional cognitive processing which increases the overall response latency.

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Longitudinal effects of physical activity on self-efficacy and cognitive processing of active and sedentary elderly women

Dementia & Neuropsychologia ◽

10.1590/s1980-57642014dn82000016 ◽

2014 ◽

Vol 8 (2) ◽

pp. 187-193

Author(s):

Sofia Rosanti ◽

Guilherme Elias da Silva ◽

Flávia Heloísa Santos

Keyword(s):

Physical Activity ◽

Cognitive Processing ◽

Self Efficacy ◽

Protective Factor ◽

Elderly Women ◽

The Elderly ◽

Mood States ◽

Longitudinal Effects ◽

One Year

ABSTRACT Previous studies support that regular physical activity in aging contributes as a protective factor against cognitive decline and improves mood states. However, there is a lack of longitudinal studies in this area. Objective: To observe possible changes in cognition related with physical activity. Methods: This study reassessed, after one-year period, 31 elderly women divided into two groups, sedentary versus active, using behavioral scales and cognitive tests. Results: The active group exhibited significantly enhanced performance in general cognitive function, particularly on tasks of episodic memory and praxis, and also on the mood states scale compared to the sedentary group. The active women also reported higher self-efficacy. Conclusion: Long-term physical activity promoted improvement on quality of life in the elderly women.

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The Effect of Non-Native Accents and Stereotypes on Speaker Perception and Comprehension

Armenian Folia Anglistika ◽

10.46991/afa/2017.13.1-2.119 ◽

2017 ◽

Vol 13 (1-2 (17)) ◽

pp. 119-128

Author(s):

Susanna Baghdasaryan

Keyword(s):

Cognitive Processing ◽

Native Speakers ◽

Negative Attitude ◽

Linguistic Community ◽

Cognitive Mechanisms ◽

Native Speech ◽

Cognitive Techniques ◽

Per Se ◽

Implicit And Explicit ◽

Better Than

The paper argues that linguistic forms per se do not have any positive or negative meaning and that one form is not better than the other. However, this is not fully perceived outside the narrow linguistic community. Very often it is demonstrated by the apparent stigmatization of non-native accents by native speakers of the language. This phenomenon seems true in reference to many communities and languages. Different sociolinguists have conducted research to prove the ungrounded nature of linguistic partiality. They try to account for the listeners’ attitudes towards non-native speech by incorporating the model of dual cognitive processing methods, namely implicit and explicit. They believe that attitudes are formed by the interaction of these two cognitive mechanisms. The negative attitude can be cured by application of more explicit cognitive techniques.

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Exposure to Criticism Modulates Left but Not Right Amygdala Functional Connectivity in Healthy Adolescents: Individual Influences of Perceived and Self-Criticism

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.673805 ◽

2021 ◽

Vol 12 ◽

Author(s):

Sam Luc Bart Bonduelle ◽

Qinyuan Chen ◽

Guo-Rong Wu ◽

Caroline Braet ◽

Rudi De Raedt ◽

...

Keyword(s):

Functional Connectivity ◽

Cognitive Processing ◽

Emotional Regulation ◽

Emotional Processing ◽

Negative Mood ◽

Mood States ◽

Brain Maturation ◽

Seed Region ◽

Brain Areas ◽

Perceived Criticism

Background: Frequent exposure to criticism is a known risk factor for various adult psychiatric disorders. Adolescents may be even more vulnerable to (parental) criticism, as their imbalanced brain maturation makes them prone to stronger mood changes and less effective emotional regulation. Identifying which adolescent subgroups are more vulnerable than others could be of great clinical relevance. Perceived criticism (PC) and self-criticism (SC), two related but distinct traits, could well be crucial vulnerability factors.Hypotheses: After exposure to criticism during fMRI scanning, rapid changes in amygdalar functional connectivity (FC) with other brain areas involved in emotion regulation and social cognitive processing will occur. These changes will depend on trait moderators, such as the adolescents' proneness to (a) perceive others as critical of them (PC) or (b) perceive themselves positively or negatively (SC).Methods: Sixty-four healthy 14–17-year-olds were exposed to a series of auditory comments. Changes in mood states were assessed based on the Profile of Mood States (POMS) prior to and after exposure to these segments. Pre- and post-experiment FC of the left and right amygdalae with other brain areas were also measured. Correlates between FC changes and psychometric measures—including the perceived criticism measure (PCM) and self-perception profile for adolescents (SPPA)—were assessed.Results: First, after being criticized, FC increases of the left amygdala seed region with brain areas related to sustained emotional processing were found, but no right amygdalar FC changes. Second, there was a significant positive partial correlation between individual PCM scores and FC changes between the left amygdala seed region and the left precuneus and left superior parietal cortex, both part of the default mode network.Conclusion: Exposure to criticism resulted in a rapid negative mood change accompanied by an increase in FC between the left amygdala and regions known to be involved in sustained emotional processing, but no right amygdalar FC changes. Furthermore, higher PC but not SC was correlated with stronger left amygdalar FC increases with these regions, suggesting an elevated vulnerability for disturbed emotional processing, as observed in mood disorders, in healthy adolescents with higher PCM scores.

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Origin of Hepatic Nuclear Inclusion Bodies

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100072575 ◽

1973 ◽

Vol 31 ◽

pp. 426-427

Author(s):

F. G. Zaki ◽

J. A. Greenlee ◽

C. H. Keysser

Keyword(s):

Inclusion Bodies ◽

Storage Disease ◽

Glycogen Storage ◽

Nutritional Deficiencies ◽

Nuclear Inclusion ◽

Electron Microscopic ◽

Human Liver Cells ◽

Microscopic Studies ◽

Per Se ◽

Experimental Liver

Nuclear inclusion bodies seen in human liver cells may appear in light microscopy as deposits of fat or glycogen resulting from various diseases such as diabetes, hepatitis, cholestasis or glycogen storage disease. These deposits have been also encountered in experimental liver injury and in our animals subjected to nutritional deficiencies, drug intoxication and hepatocarcinogens. Sometimes these deposits fail to demonstrate the presence of fat or glycogen and show PAS negative reaction. Such deposits are considered as viral products.Electron microscopic studies of these nuclei revealed that such inclusion bodies were not products of the nucleus per se but were mere segments of endoplasmic reticulum trapped inside invaginating nuclei (Fig. 1-3).

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The Eleventh Circuit Holds that Agreements in which Pharmaceutical Companies Pay Generic Companies Not to Compete May be Valid

The Journal of Law Medicine & Ethics ◽

10.1017/s107311050000749x ◽

2004 ◽

Vol 32 (1) ◽

pp. 181-184

Author(s):

Amy Garrigues

Keyword(s):

Pharmaceutical Companies ◽

Court Decisions ◽

Patent Holder ◽

Trial Court ◽

Court Of Appeals ◽

The Us ◽

Antitrust Laws ◽

Per Se ◽

Appeals Court ◽

Two Sides

On September 15, 2003, the US. Court of Appeals for the Eleventh Circuit held that agreements between pharmaceutical and generic companies not to compete are not per se unlawful if these agreements do not expand the existing exclusionary right of a patent. The Valley DrugCo.v.Geneva Pharmaceuticals decision emphasizes that the nature of a patent gives the patent holder exclusive rights, and if an agreement merely confirms that exclusivity, then it is not per se unlawful. With this holding, the appeals court reversed the decision of the trial court, which held that agreements under which competitors are paid to stay out of the market are per se violations of the antitrust laws. An examination of the Valley Drugtrial and appeals court decisions sheds light on the two sides of an emerging legal debate concerning the validity of pay-not-to-compete agreements, and more broadly, on the appropriate balance between the seemingly competing interests of patent and antitrust laws.

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Fusion and Fission Processes in Exocytosis: Possible Roles for Synexin and Osmotic Lysis in the Two Events

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s1431927600002634 ◽

1980 ◽

Vol 38 ◽

pp. 594-597

Author(s):

H.B. Pollard ◽

C.E. Creutz ◽

C.J. Pazoles ◽

J.H. Scott

Keyword(s):

Small Molecules ◽

Chromaffin Cells ◽

Adrenal Glands ◽

General Concept ◽

Extracellular Calcium ◽

Large Protein ◽

Granule Membrane ◽

Osmotic Lysis ◽

Per Se ◽

Chemical Evidence

Exocytosis is a general concept describing secretion of enzymes, hormones and transmitters that are otherwise sequestered in intracellular granules. Chemical evidence for this concept was first gathered from studies on chromaffin cells in perfused adrenal glands, in which it was found that granule contents, including both large protein and small molecules such as adrenaline and ATP, were released together while the granule membrane was retained in the cell. A number of exhaustive reviews of this early work have been published and are summarized in Reference 1. The critical experiments demonstrating the importance of extracellular calcium for exocytosis per se were also first performed in this system (2,3), further indicating the substantial service given by chromaffin cells to those interested in secretory phenomena over the years.

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The S-SH Confusion Test and the Effects of Frequency Lowering

Journal of Speech Language and Hearing Research ◽

10.1044/2018_jslhr-h-18-0267 ◽

2019 ◽

Vol 62 (5) ◽

pp. 1486-1505

Author(s):

Joshua M. Alexander

Keyword(s):

Cognitive Processing ◽

Hearing Aids ◽

Response Times ◽

Nonlinear Frequency ◽

Low Frequencies ◽

Frequency Compression ◽

Negative Side ◽

Minimal Word ◽

Low Pass ◽

Negative Side Effects

PurposeFrequency lowering in hearing aids can cause listeners to perceive [s] as [ʃ]. The S-SH Confusion Test, which consists of 66 minimal word pairs spoken by 6 female talkers, was designed to help clinicians and researchers document these negative side effects. This study's purpose was to use this new test to evaluate the hypothesis that these confusions will increase to the extent that low frequencies are altered.MethodTwenty-one listeners with normal hearing were each tested on 7 conditions. Three were control conditions that were low-pass filtered at 3.3, 5.0, and 9.1 kHz. Four conditions were processed with nonlinear frequency compression (NFC): 2 had a 3.3-kHz maximum audible output frequency (MAOF), with a start frequency (SF) of 1.6 or 2.2 kHz; 2 had a 5.0-kHz MAOF, with an SF of 1.6 or 4.0 kHz. Listeners' responses were analyzed using concepts from signal detection theory. Response times were also collected as a measure of cognitive processing.ResultsOverall, [s] for [ʃ] confusions were minimal. As predicted, [ʃ] for [s] confusions increased for NFC conditions with a lower versus higher MAOF and with a lower versus higher SF. Response times for trials with correct [s] responses were shortest for the 9.1-kHz control and increased for the 5.0- and 3.3-kHz controls. NFC response times were also significantly longer as MAOF and SF decreased. The NFC condition with the highest MAOF and SF had statistically shorter response times than its control condition, indicating that, under some circumstances, NFC may ease cognitive processing.ConclusionsLarge differences in the S-SH Confusion Test across frequency-lowering conditions show that it can be used to document a major negative side effect associated with frequency lowering. Smaller but significant differences in response times for correct [s] trials indicate that NFC can help or hinder cognitive processing, depending on its settings.

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Cognitive Processing of Miscommunication in Interactive Listening: An Evaluation of Listener Indecision and Cognitive Effort

Journal of Speech Language and Hearing Research ◽

10.1044/2020_jslhr-20-00128 ◽

2021 ◽

pp. 1-17

Author(s):

Jennifer M. Roche ◽

Arkady Zgonnikov ◽

Laura M. Morett

Keyword(s):

Decision Making ◽

Cognitive Processing ◽

Language Processing ◽

Cognitive Effort ◽

Mouse Tracking ◽

Computer Mouse ◽

Decision Making Processes ◽

Computer Mouse Tracking ◽

Listening Task ◽

Processing Effort

Purpose The purpose of the current study was to evaluate the social and cognitive underpinnings of miscommunication during an interactive listening task. Method An eye and computer mouse–tracking visual-world paradigm was used to investigate how a listener's cognitive effort (local and global) and decision-making processes were affected by a speaker's use of ambiguity that led to a miscommunication. Results Experiments 1 and 2 found that an environmental cue that made a miscommunication more or less salient impacted listener language processing effort (eye-tracking). Experiment 2 also indicated that listeners may develop different processing heuristics dependent upon the speaker's use of ambiguity that led to a miscommunication, exerting a significant impact on cognition and decision making. We also found that perspective-taking effort and decision-making complexity metrics (computer mouse tracking) predict language processing effort, indicating that instances of miscommunication produced cognitive consequences of indecision, thinking, and cognitive pull. Conclusion Together, these results indicate that listeners behave both reciprocally and adaptively when miscommunications occur, but the way they respond is largely dependent upon the type of ambiguity and how often it is produced by the speaker.

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