FGF-23 and PTH levels in patients with acute kidney injury: A cross-sectional case series study

ObjectivesTo identify delays and associated factors for maternal deaths in Nepal.DesignA cross-sectional case series study of maternal deaths. An integrated verbal and social autopsy tool was used to collect quantitative and qualitative information regarding three delays. We recorded death accounts and conducted social autopsy by means of community Focus Group Discussions for each maternal death; and analysed data by framework analysis.SettingSixty-two maternal deaths in six districts in three provinces of Nepal.ResultsNearly half of the deceased women (45.2%) were primiparous and one-third had no formal education. About 40% were from Terai/Madhesi and 30.6% from lower caste. The most common place of death was private hospitals (41.9%), followed by public hospitals (29.1%). Nearly three-fourth cases were referred to higher health facilities and median time (IQR) of stay at the lower health facility was 120 (60–180) hours. Nearly half of deaths (43.5%) were attributable to more than one delay while first and third delay each contributed equally (25.8%). Lack of perceived need; perceived cost and low status; traditional beliefs and practices; physically inaccessible facilities and lack of service readiness and quality care were important factors in maternal deaths.ConclusionsThe first and third delays were the equal contributors of maternal deaths. Interventions related to birth preparedness, economic support and family planning need to be focused on poor and marginalised communities. Community management of quick transportation, early diagnosis of pregnancy risks, accommodation facilities near the referral hospitals and dedicated skilled manpower with adequate medicines, equipment and blood supplies in referral hospitals are needed for further reduction of maternal deaths in Nepal.

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A Retrospective, Multicenter, Cross-Sectional Case Series Study Evaluating Outcomes of CAD/CAM Abutments on Implants from Four Manufacturers: 4-Year Mean Follow-up

The International Journal of Oral & Maxillofacial Implants ◽

10.11607/jomi.8840 ◽

2021 ◽

Vol 36 (5) ◽

pp. 966-976

Author(s):

Christopher Barwacz ◽

Kumar Shah ◽

Nurit Bittner ◽

William Parker ◽

Toni Neumeier ◽

...

Keyword(s):

Case Series ◽

Cross Sectional ◽

Case Series Study ◽

Cad Cam ◽

Series Study

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SEVERITY OF SNAKE BITE WITH EARLY PREDICTORS OF THROMBOCYTOPENIA AND ALBUMINURIA IN ACUTE KIDNEY INJURY

10.36106/gjra/3104201 ◽

2020 ◽

pp. 1-3

Author(s):

Ashmitha Padma ◽

Pramila Devi

Keyword(s):

Acute Kidney Injury ◽

Serum Creatinine ◽

Case Series ◽

Kidney Injury ◽

P Value ◽

Medical College ◽

Urine Albumin ◽

Early Predictors ◽

Case Series Study ◽

Prospective Case Series

Snakebites are very common public health problems which is caused by venomous arthropods effecting many organs and causing fatal emergencies. Snakebite can cause direct or indirect nephro toxicity, especially hematotoxic snakebites. It is important to know the early predictors of acute kidney injury so as to prevent the complications early. Methods: This is a prospective case series study conducted at S. Nijalingappa Medical College and Hangal Shri Kumareshwar Hospital and Research center, Bagalkot from June 2018 to June 2019. Results: Total of 51 patients were included in this study who satisfied the inclusion and exclusion criteria. It was found that 35 patients had thrombocytopenia with p value of <0.002, which was highly significant. Serum creatinine was found to be more than 1.2mg/dl in 35 patients and the p value was <0.002 which was highly significant and urine albumin was also found to be more which p avalue was<0.001. among the study subjects 70% of them were found to have thrombocytopenia with albuminuria and increase in serum creatinine.

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Stillbirths at the National Referral Hospital in Bhutan: a historical description of the rate and related factors, 2006-2008

Bhutan Health Journal ◽

10.47811/bhj.38 ◽

2017 ◽

Vol 3 (1) ◽

pp. 19-23

Author(s):

Phurb Dorji ◽

Thinley Dorji

Keyword(s):

Case Series ◽

Referral Hospital ◽

Antenatal Visit ◽

Cross Sectional Survey ◽

Related Factors ◽

Cross Sectional ◽

Case Series Study ◽

Ethical Approval ◽

Series Study ◽

National Referral Hospital

Introduction: A fetal death or stillbirth is a baby born weighing >500 grams and with no signs of life at or after 28 weeks of gestation. Methods: This was a cross-sectional survey to estimate the rate of stillbirths and a case series study to describe all stillbirths occurring at Bhutan’s national referral centre, Jigme Dorji Wangchuck National Referral Hospital (JDWNRH), from June 2006 to July 2008. Ethical approval was granted by the Ministry of Health. All pregnant women who had stillbirths with fetuses weighing >500 grams were included. Antenatal and socio-demographic details and examination of the newborn were abstracted from records. Results: There were 96 stillbirths among 5,417 births at JDWNRH, for a rate of 17.72 per 1,000 births. The mean age of women with stillbirths was 26.5 years (range 15 to 44 years). The majority of stillbirths occurred in women aged between 20 to 34 years and in primipara. The majority (87.5%) of the women had at least one antenatal visit, 69.8% had at least two visits while 12.5% had zero antenatal visits. At birth, there were 39 fresh stillbirths and 57 macerated. Seventy-six stillborn babies (79.2%) had weight lesser than 2500 grams. The most common cause was congenital infections, severe pregnancy induced hypertension, prelabour premature rupture of membranes, chorioamnionitis, and prolonged rupture of membranes. Congenital anomalies causing death was relatively lower in rank. The proportion of unexplained stillbirths was 15.6%. Conclusions: The rate of stillbirth was substantially high in our population. Many of the causes of stillbirth were preventable and measures can be reinforced to improve birth outcomes.

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Is lack of patient knowledge a cause of poorly controlled diabetes mellitus?

10.53350/pjmhs211592302 ◽

2021 ◽

Vol 15 (9) ◽

pp. 2302-2304

Author(s):

Muhammad Ahmad Tahir Ch ◽

Nauman Ismat Butt ◽

Hiba Shakeel ◽

Mehrun Nisa Fatima Gondal ◽

Hamdah Saeed ◽

...

Keyword(s):

Diabetes Mellitus ◽

Case Series ◽

Diabetic Patients ◽

Patient Knowledge ◽

Keywords Diabetes ◽

Cross Sectional ◽

Pakistani Population ◽

Case Series Study ◽

Study Population ◽

Series Study

Background: Diabetes is a chronic debilitating disease. A large percentage of Pakistani population suffers from this disease and its consequences. Awareness regarding the disease and its management is poor. Aim: To evaluate the awareness of diabetic patients presenting at Services Hospital regarding diabetes. Study design: Observational cross-sectional case-series study. Settings & duration: Department of medicine Services hospital, Lahore, from 01-07-2020 to 31-12- 2020. Methodology: We interviewed 100 diabetic patients who presented to the OPD/ER of the hospital. All the participants were selected randomly. A simple questionnaire was used to record the demographic details of the patients as well as their response to a series of 13 questions. The knowledge of the participants was taken to be good if they were able to answer at least 8 or more of the questions correctly. Results: Overall, a total of 100 adults were interviewed. The median age of the study population was 52.06 years with standard deviation of 13.49 years. There were 46 females and 54 males. Only 30% of the patients had sufficient knowledge regarding the disease and its complications. When stratification was done there was no significant association with any variable. Conclusion: There is a lack of knowledge among the diabetes regarding their disease. Even education from doctors is not helpful in this regard. Once patients are aware of the disease and its complications the glycemic control improves markedly. Keywords: Diabetes Mellitus, Poor Control, Patient Knowledge

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DENTAL FLOSS

The Professional Medical Journal ◽

10.29309/tpmj/2016.23.11.1763 ◽

2016 ◽

Vol 23 (11) ◽

pp. 1364-1367

Author(s):

Shazia Parveen Rajpar ◽

Munir Ahmed Banglani ◽

Suneel Kumar Punjabi ◽

Miss Priya

Keyword(s):

Case Series ◽

Health Sciences ◽

Dental Students ◽

Cross Sectional ◽

Dental Floss ◽

Case Series Study ◽

Medical Health ◽

Knowledge And Practice ◽

Cleaning Methods ◽

Series Study

Objectives: To assist the concept and use of dental floss amongundergraduate dental students of Liaquat University of Medical & Health sciences,Jamshoro. Study Design: Cross-sectional, descriptive case series study. Setting:Institute of Dentistry, Liaquat University of Medical Health, Jamshoro, Pakistan.Period: June 2015 to December 2015. Methodology: In this study 192 studentsof BDS Department, Institute of Dentistry, Liaquat University of Medical & HealthScience, Jamshoro were selected. Questions related to assess the knowledge 87.14%students knew what dental floss was. Results: 74.29% students knew that dentalfloss remove plaque from interdental areas, whereas 25.71% replied don’t know.48.57% of the students thought that dental floss should be customarily used alongwith tooth brushing every day, 24.29% of the students thought that dental floss harmsthe interdental gingiva, whereas majority 40% said that it would not harm the gingiva,35.71% replied don’t know. only 18.57% respondent thought that toothbrushes withadvanced bristles designs would remove interdental plaque similar to dental floss,whereas majority (60%) of the respondent had no any idea about the effectiveness oftwo cleaning methods, practice of using dental floss 18.57% of students use interdentalaids commonly floss and while 81.43% did not use dental floss. 27.14% of the studysubjects use some other interdental aids like tooth picks to clean interdental areas,whereas 72.86% did not follow any other interdental cleaning practice. Conclusion:This study has focused light on the knowledge and practice of interdental aid, sofurther studies are needed. Finally, it could be concluded that awareness regardingdental floss needs to be bolstered in the population as preventive oral health carebehavior.

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Detection of SARS-CoV-2 in the tears and conjunctival secretions of Coronavirus disease 2019 patients

The Journal of Infection in Developing Countries ◽

10.3855/jidc.13224 ◽

2020 ◽

Vol 14 (09) ◽

pp. 977-981 ◽

Cited By ~ 1

Author(s):

Hüseyin Kaya ◽

Ahmet Çalışkan ◽

Mehmet Okul ◽

Tuğba Sarı ◽

İsmail Hakkı Akbudak

Keyword(s):

Case Series ◽

Cross Sectional Study ◽

University Hospital ◽

Cross Sectional ◽

Ocular Manifestations ◽

Case Series Study ◽

Eye Symptoms ◽

Polymerase Chain ◽

Mean Time ◽

Series Study

Introduction: Current studies suggest that tears and conjunctival secretions may be an important transmission route in coronavirus disease 2019 (COVID-19). The study aims to evaluate the presence of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) virus in tears and conjunctival secretion of patients with COVID-19. Methodology: A prospective interventional case series study was performed, and 32 patients with COVID-19 were selected at the Pamukkale University Hospital from 15 to 22 May 2020. The tear and conjunctival samples were collected by a conjunctival swab. Each specimen was sent to the laboratory for reverse transcription-polymerase chain reaction (RT-PCR) analyses. To avoid cross-infection, gloves and personal protective equipment were changed after collecting each sample. Results: 32 patients (18 male, 14 female) with Covid-19 were included in this cross-sectional study. The average age of the patients was 52.81 ± 16.76 years. By the time of the first collection of conjunctival-tear samples, the mean time of the onset of complaints was 6.84 ± 6.81 (1-35) days. Tear-conjunctival samples from 5 patients (16%) without conjunctivitis yielded positive PCR results, 3 of whom had positive and 2 negative nasopharyngeal PCR results. Conclusions: Five of 32 patients (16 %) without conjunctivitis or any eye symptoms had viral RNA in their tear-conjunctival samples. The possibility of transmission via tears and conjunctival secretions should be recognized even in the absence of conjunctivitis or other ocular manifestations.

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Etiological spectrum and short term outcome of acute kidney injury in children: a prospective study

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20193737 ◽

2019 ◽

Vol 6 (5) ◽

pp. 2121

Author(s):

K. Mahesh ◽

Vishwanath B. ◽

Kalpana S.

Keyword(s):

Acute Kidney Injury ◽

Hypovolemic Shock ◽

Case Series ◽

Kidney Injury ◽

Critically Ill Children ◽

Base Line ◽

Short Term ◽

Term Outcome ◽

Short Term Outcome ◽

Case Series Study

Background: Acute Kidney Injury is a common condition in critically ill children, and it is independently associated with increased mortality. Etiology of AKI in admitted patients is multi factorial. The present study was conducted to determine possible etiologies and to know short term outcome.Methods: A prospective case series study was conducted in our PICU from Nov 2014 to October 2015. The cases fulfilling criteria as AKI, as per definition were included in study. The urine output was monitored, base line blood urea and serum creatinine was estimated at admission and on alternate days till recovery. Investigations were done to know exact etiology of prerenal, renal or post renal AKI. Cases were managed accordingly and short term outcome was noted.Results: Out of 150 cases studied, 87(58%) were boys and 63(42%) were girls. Ninety three cases (62%) had oliguria and remaining patients had non-oliguric AKI. Majority of cases in the study belonged to prerenal AKI, followed by renal and post renal AKI. Amongst 150 cases,136 children managed conservatively,11 cases required hemodialysis and 3 cases peritoneal dialysis. In our study, 16 cases succumbed with mortality of 10.66%.Conclusion: AKI is common associated condition in children admitted to PICU. AKI is commonly seen with acute gastroenteritis with severe dehydration, sepsis, glomerulonephritis and dengue shock syndrome. Most of these conditions are easily preventable. Early and effective management of hypovolemic shock and sepsis is also crucial in prevention of AKI.

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Clinical and Laboratory Profile of Hospitalized Symptomatic COVID-19 Patients: Case Series Study From the First COVID-19 Center in the UAE

Frontiers in Cellular and Infection Microbiology ◽

10.3389/fcimb.2021.632965 ◽

2021 ◽

Vol 11 ◽

Author(s):

Suad Hannawi ◽

Haifa Hannawi ◽

Kashif Bin Naeem ◽

Noha Mousaad Elemam ◽

Mahmood Y. Hachim ◽

...

Keyword(s):

Cardiac Injury ◽

Laboratory Data ◽

Case Series ◽

Kidney Injury ◽

Severe Infection ◽

International Normalized Ratio ◽

Cross Sectional ◽

Icu Admission ◽

Case Series Study ◽

The Mean

IntroductionCOVID-19 is raising with a second wave threatening many countries. Therefore, it is important to understand COVID-19 characteristics across different countries.MethodsThis is a cross-sectional descriptive study of 525 hospitalized symptomatic COVID-19 patients, from the central federal hospital in Dubai-UAE during period of March to August 2020.ResultsUAE’s COVID-19 patients were relatively young; mean (SD) of the age 49(15) years, 130 (25%) were older than 60 and 4 (<1%) were younger than 18 years old. Majority were male(47; 78%). The mean (SD) BMI was 29 (6) kg/m2. While the source of contracting COVID-19 was not known in 369 (70%) of patients, 29 (6%) reported travel to overseas-country and 127 (24%) reported contact with another COVID-19 case/s. At least one comorbidity was present in 284 (54%) of patients and 241 (46%) had none. The most common comorbidities were diabetes (177; 34%) and hypertension (166; 32%). The mean (SD) of symptoms duration was 6 (3) days. The most common symptoms at hospitalization were fever (340; 65%), cough (296; 56%), and shortness of breath (SOB) (243; 46%). Most of the laboratory values were within normal range, but (184; 35%) of patients had lymphopenia, 43 (8%) had neutrophilia, and 116 (22%) had prolong international normalized ratio (INR), and 317 (60%) had high D-dimer. Chest x ray findings of consolidation was present in 334 (64%) of patients and CT scan ground glass appearance was present in 354 (68%). Acute cardiac injury occurred in 124 (24%), acute kidney injury in 111 (21%), liver injury in 101 (19%), ARDS in 155 (30%), acidosis in 118 (22%), and septic shock in 93 (18%). Consequently, 150 (29%) required ICU admission with 103 (20%) needed mechanical ventilation.ConclusionsThe study demonstrated the special profile of COVID-19 in UAE. Patients were young with diabetes and/or hypertension and associated with severe infection as shown by various clinical and laboratory data necessitating ICU admission.

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