scholarly journals Body fat percentage and CRP correlates with a composite score of vascular risk markers in healthy, young adults - The Lifestyle, Biomarkers, and Atherosclerosis (LBA) study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Paul Pettersson-Pablo ◽  
Yang Cao ◽  
Torbjörn Bäckström ◽  
Torbjörn K. Nilsson ◽  
Anita Hurtig-Wennlöf
Keyword(s):  
Young Adults ◽  
Cardiovascular Risk ◽  
Body Fat ◽  
Structure And Function ◽  
Body Fat Percentage ◽  
Vascular Structure ◽  
Fat Percentage ◽  
Cluster Analyses ◽  
And Function

Abstract Background Identification of early signs of atherosclerosis in young adults have the potential to guide early interventions to prevent later cardiovascular disease. We therefore analyzed measures of vascular structure and function and biomarkers of cardiovascular risk in a sample of young healthy adults. Methods Pulse-wave velocity (PWV), carotid-intima media thickness (cIMT) and augmentation index (AIX) were measured in 834 healthy non-smokers (ages 18.0–25.9). Emphasis was put on discriminating between individuals having a vascular structure and function associated with a higher or lower risk, and cluster analysis algorithms were employed to assign the subjects into groups based on these vascular measurements. In addition, a vascular status score (VSS) was calculated by summarizing the results according to quintiles of the vascular measurements. The associations between VSS and cardiovascular biomarkers were examined by regression analyses. Results The cluster analyses did not yield sufficiently distinct clustering (groups of individuals that could be categorized unequivocally as having either a vascular structure and function associated with a higher or lower CVD risk). VSS proved a better classificatory variable. The associations between VSS and biomarkers of cardiovascular risk were analyzed by univariable and multivariable regressions. Only body fat percentage and C-reactive protein (CRP) were independently associated with VSS. Conclusions A VSS calculation, which integrates PWV, cIMT, and AIX measurements is better suited for cardiovascular risk evaluation in young adults than cluster analyses. The independent associations of VSS with body fat percentage and CRP highlight the decisive role of adiposity and systemic inflammation in early atherosclerotic progression and suggests a subordinate role of insulin and lipid metabolism in this age span.

scholarly journals Body Fat Percentage, Waist Circumference and Body Mass Index are Correlated with Nitric Oxide Levels in Young Adults with Central Obesity

2021 ◽  
Vol 5 (1) ◽  
pp. 1
Author(s):  
Feriyandi Nauli ◽  
Nurhasanah Nurhasanah ◽  
Endang Mahati ◽  
Udin Bahrudin
Keyword(s):  
Nitric Oxide ◽  
Body Mass Index ◽  
Young Adults ◽  
Waist Circumference ◽  
Body Mass ◽  
Body Fat ◽  
Central Obesity ◽  
Subcutaneous Fat ◽  
Body Fat Percentage ◽  
Fat Percentage

Background: Central obesity stands for the corner-stone of cardio-metabolic health, while nitric oxide (NO) is a major regulator of cardiovascular function. To day, the correlation between serum NO metabolites nitrate/nitrite and the obesity components in young adults remains elusive. Thus, this current study was conducted to know the correlation between serum NO metabolites levels and body fat percentage, waist circumference (WC) as well as body mass index (BMI) in young adults with central obesity.Materials and Methods: A cross-sectional study was conducted in Riau, Indonesia, involving 79 young adults aged 18-25 years, composing of 39 and 40 subjects with and without central obesity, respectively. Anthropometric measurements were performed to assess WC and BMI. Body fat percentage was measured using bioelectrical impedance analysis and serum NO metabolites levels were assessed using Griess methods.Results: Levels of serum NO metabolites were significant higher in the subjects with central obesity (168.41±12.64 μmol/L) than that of normal subjects (70.57±44.99 μmol/L, p<0.001), but the levels were no significant different between male and female subjects. Serum NO metabolites levels were strongly correlated with total body fat (r=0.618, p<0.001), visceral fat (r=0.733, p<0.001), subcutaneous fat (r=0.547, p<0.001), WC (r=0.717, p<0.001) and BMI (r=0.788, p<0.001).Conclusions: For young adults in Riau, Indonesia, levels of serum NO metabolites are higher in the central obesity group than that of the normal. In this population, body fat percentage, waist circumference and body mass index are correlated with serum nitric oxide metabolites levels.Keywords: nitric oxide, body fat percentage, young adults, central obesity

scholarly journals Anthropometric Obesity Indices, Body Fat Percentage, and Grip Strength in Young Adults with different Physical Activity Levels

2019 ◽  
Vol 4 (3) ◽  
pp. 51
Author(s):  
Söğüt ◽  
Kaya ◽  
Altunsoy ◽  
Clark ◽  
Clemente ◽  
...  
Keyword(s):  
Physical Activity ◽  
Young Adults ◽  
Grip Strength ◽  
Body Fat ◽  
Activity Level ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Physically Active ◽  
Obesity Indices ◽  
Activity Groups

The purposes of this study were to determine whether moderately physically active (MPA) and highly physically active (HPA) male (n = 96, age = 22.5 ± 1.7 years) and female (n = 85, age = 21.3 ± 1.6 years) young adults differed in their anthropometric obesity indices (AOIs), body fat percentage (BF%), and muscular strength, and also to examine the associations between physical activity level (PAL) and the abovementioned variables. Participants were measured for body height and weight, BF%, waist and hip circumferences, and maximal isometric grip strength. According to their PAL, estimated by the short version of the International Physical Activity Questionnaire, they were assigned to MPA and HPA subgroups. Regardless of gender, results indicated that participants in the MPA groups had significantly higher values of body weight, waist and hip circumference, BF%, and BMI than participants in the HPA groups. No significant differences were found between physical activity groups in terms of grip strength. The AOIs and BF% were found to be significantly and negatively correlated with the PAL in both genders. In conclusion, the findings of the study suggest that high habitual physical activity is associated with lower adiposity markers. However, the differences in the hand grip strength of the contrasting activity groups were negligible.

scholarly journals HDL cholesterol efflux capacity is inversely associated with subclinical cardiovascular risk markers in young adults: The cardiovascular risk in Young Finns study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Monika Hunjadi ◽  
Claudia Lamina ◽  
Patrick Kahler ◽  
Tamara Bernscherer ◽  
Jorma Viikari ◽  
...  
Keyword(s):  
Young Adults ◽  
Cardiovascular Risk ◽  
Cholesterol Efflux ◽  
Subclinical Atherosclerosis ◽  
Structure And Function ◽  
Risk Markers ◽  
Arterial Structure ◽  
And Function ◽  
Young Finns Study

Abstract The atherogenic process begins already in childhood and progresses to symptomatic condition with age. We investigated the association of cholesterol efflux capacity (CEC) and vascular markers of subclinical atherosclerosis in healthy, young adults. CEC was determined in 2282 participants of the Young Finns study using cAMP treated 3H-cholesterol-labeled J774 cells. The CEC was correlated to baseline and 6-year follow-up data of cardiovascular risk factors and ultrasound measurements of arterial structure and function. CEC was higher in women, correlated with total cholesterol, HDL-C, and apolipoprotein A-I, but not with LDL-C or apolipoprotein B. Compared to the lowest CEC quartile, the highest CEC quartile was significantly associated with high CRP levels and inversely associated with adiponectin. At baseline, high CEC was associated with decreased flow-mediated dilation (FMD) and carotid artery distensibility, as well as an increased Young's modulus of elasticity, indicating adverse changes in arterial structure, and function. The association reversed with follow-up FMD data, indicating the interaction of preclinical parameters over time. A higher CEC was directly associated with a lower risk of subclinical atherosclerosis at follow-up. In young and healthy subjects, CEC was associated with important lipid risk parameters at baseline, as in older patients and CAD patients, but inversely with early risk markers for subclinical atherosclerosis.

Correlates of vascular structure and function measures in asymptomatic young adults: The Bogalusa Heart Study

2006 ◽  
Vol 189 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Azad R. Bhuiyan ◽  
Sathanur R. Srinivasan ◽  
Wei Chen ◽  
Timir K. Paul ◽  
Gerald S. Berenson
Keyword(s):  
Young Adults ◽  
Structure And Function ◽  
Vascular Structure ◽  
Bogalusa Heart Study ◽  
Heart Study ◽  
And Function

Decreased Renal Function Induced by High-Fat Diet in Wistar Rat: The Role of Plasma Angiotensin Converting Enzyme 2 (ACE2)

2019 ◽  
Vol 12 (3) ◽  
pp. 1279-1287
Author(s):  
Ridwan Ridwan ◽  
Rosdiana Natzir ◽  
Haerani Rasyid ◽  
Ilhamjaya Patellongi ◽  
Mochammad Hatta ◽  
...  
Keyword(s):  
Renal Function ◽  
Body Weight ◽  
Body Fat ◽  
High Fat Diet ◽  
Early Stage ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Angiotensin Converting Enzyme 2 ◽  
Obesity Index

Researches on the effects of High Fat Diet (HFD) on decreased renal function with cystatin C (cysC) serum levels biomarker are few and show different findings. Renin Angiotensin System (RAS) plays a key role in controlling renal function and one of the integral components of the RAS is Angiotensin Converting Enzyme 2 (ACE2). Research on the relationship between plasma ACE2 levels with serum cysC levels in animals induced by HFD has not been done. We hypothesize that administration of HFD can cause a decline in early stage renal function through the role of ACE2. 30 male wistar rats aged 10-12 weeks (body weight between 170-220 grams) were randomly divided into 5 groups (6 rats/group): baseline, normal diet for 8 weeks (ND8), ND for 16 weeks (ND16), HFD for 8 weeks (HFD8) and HFD for 16 weeks (HFD16). Body weight and naso-anal length were measured to get the index value of obesity and body fat percentage. Obesity index measured are lee index, rohrer index and TM index. Blood samples obtained by intracardiac for examination of plasma ACE2 levels and serum cysC levels. After 8 and 16 weeks, HFD increases body weight, obesity index and body fat percentage. HFD also increases plasma ACE2 levels and serum cysC levels. Body weight, obesity index and body fat percentage have a positive correlation with plasma ACE2 levels. Plasma ACE2 levels were positively correlated with serum cysC levels. HFD causes a decrease of early stage renal function as evidenced by the increase in serum cysC levels. Plasma ACE2 levels play a role in the pathogenesis of the decline in early stage renal function induced by HFD.

The estimation of cardiovascular risk factors by body mass index and body fat percentage in Korean male adults

Metabolism ◽  
2009 ◽  
Vol 58 (6) ◽  
pp. 765-771 ◽  
Author(s):  
Young Gyu Cho ◽  
Hong Ji Song ◽  
Jin Myoung Kim ◽  
Kyung Hee Park ◽  
Yu Jin Paek ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Body Mass ◽  
Body Fat ◽  
Body Fat Percentage ◽  
Fat Percentage
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