scholarly journals The impact of chest pain center on treatment delay of STEMI patients: a time series study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaolin Sun ◽  
Bo Yao ◽  
Kexin Shi ◽  
Yajiong Xue ◽  
Huigang Liang
Keyword(s):  
Time Series ◽  
Chest Pain ◽  
Informed Consent ◽  
Coronary Intervention ◽  
Treatment Delay ◽  
Hospital Treatment ◽  
Time Series Regression ◽  
Large Hospital ◽  
Pain Center ◽  
The Impact

Abstract Objective To study the effect of the establishment of a Chest Pain Center (CPC) on the treatment delay of ST-elevation myocardial infarction (STEMI) patients and the influencing factors of treatment delay in a large hospital in China. Methods The study subjects are 318 STEMI patients admitted between August 2016 and July 2019 to a large general hospital in Henan, China. Data were extracted from the electronic medical records after removing personal identifiable information. The interrupted time series regression was used to analyze the treatment delay of patients before and after the CPC establishment. Results After the CPC establishment, the patients’ pre-hospital and in-hospital treatment delays were significantly reduced. SO-to-FMC (Symptom Onset to First Medical Contact time) decreased by 49.237 min and D-to-B (Door to Balloon time) decreased by 21.931 min immediately after the CPC establishment. In addition, SO-to-FMC delay is significantly correlated with age, occupation, nocturnal onset, and the way to hospital. D-to-B delay is significantly associated with time from initial diagnosis to informed consent of percutaneous coronary intervention (PCI), catheterization lab activation time, and time for PCI informed consent. Conclusion The CPC significantly reduced the treatment delay of STEMI patients undergoing PCI.

Abstract P250: The Impact of Recreational Cannabis Legalization on All-cause Hospitalizations and Acute Cardiovascular Event Hospitalizations in Colorado

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Abra M Jeffers ◽  
James Lightwood ◽  
Salomeh Keyhani
Keyword(s):  
Time Series ◽  
Cardiovascular Events ◽  
Cardiovascular Health ◽  
Artery Bypass ◽  
Interrupted Time Series ◽  
Coronary Intervention ◽  
Secondary Outcome ◽  
Time Series Regression ◽  
Significant Difference ◽  
The Impact

Background: Cannabis may have adverse consequences for cardiovascular health. Colorado decriminalized cannabis on November 2012 and retail sales of cannabis began in January 2014. We examined whether the overall rate of hospitalizations and hospitalizations for acute cardiovascular events (ACE) increased in Colorado after legalization. Hypothesis: We hypothesized that the rates of all-cause hospitalizations and ACE would increase post legalization of recreational cannabis. Methods: The State Inpatient Database (SID) for Colorado, available through Healthcare Cost and Utilization Project was analyzed using interrupted time-series methods to assess whether increases in sales of marijuana affected the rates of overall hospitalization and hospitalization for ACE, post legalization of cannabis. The time analyzed included January 2008 through September 2015. We ended the data of analysis on October 1 2015, because ICD-10 codes were implemented in October 2015. The primary outcome, rate of hospitalizations, was measured by total unique inpatient admissions within the SID for each monthly time period. The secondary outcome, ACE, was identified using ICD-9 diagnostic codes for myocardial infarction (410), stroke (430, 431, 433, 434, 436), and ICD-9 procedure codes for coronary artery bypass surgery (36.1x), and percutaneous coronary intervention (36.0x, 0.66). In the interrupted time series regression models we accounted for seasonality and consumption of cigarettes and alcohol using a proxy of sales tax collected each month for cigarettes and alcohol. In the ACE models, we controlled for seasonality, sales of cigarettes and average monthly air temperature. We also examined the effect of legalization on the same outcomes in men and women and different age subgroups. Results: While overall rates of hospitalizations decreased somewhat over the study period, there was no statistically significant difference in hospitalizations rates, neither in the regression intercept (for immediate change) (p=0.94) or slope (p=0.97), after the legalization of recreational cannabis. Similarly, ACE rates decreased over the time frame, but there were no significant changes in rate intercept (p=0.80) or slope (p=0.71) post legalization. The subgroup analyses by age category and gender for hospitalizations and ACE also showed no significant differences in rates pre and post legalization. Conclusions: We found no evidence that overall hospitalizations and hospitalizations for ACE increased due to legalizing recreational cannabis in Colorado. A limitation of our study was that Colorado had already implemented a medical marijuana program in 2000. Recreational legalization may not have led to a significant increase in users. Future studies should examine the link between legalization and cardiovascular events in other states with a different trajectory of legalization.

scholarly journals Relationship between daily suicide counts and temperature in England and Wales

2007 ◽  
Vol 191 (2) ◽  
pp. 106-112 ◽  
Author(s):  
Lisa A. Page ◽  
Shakoor Hajat ◽  
R. Sari Kovats
Keyword(s):  
Time Series ◽  
Seasonal Fluctuation ◽  
Daily Temperature ◽  
Short Term ◽  
Time Series Regression ◽  
England And Wales ◽  
Increased Risk ◽  
Hot Weather ◽  
The Impact ◽  
The Relationship

BackgroundSeasonal fluctuation in suicide has been observed in many populations. High temperature may contribute to this, but the effect of short-term fluctuations in temperature on suicide rates has not been studied.AimsTo assess the relationship between daily temperature and daily suicide counts in England and Wales between 1 January 1993 and 31 December 2003 and to establish whether heatwaves are associated with increased mortality from suicide.MethodTime-series regression analysis was used to explore and quantify the relationship between daily suicide counts and daily temperature. The impact of two heatwaves on suicide was estimated.ResultsNo spring or summer peak in suicide was found. Above 18 °, each 1 ° increase in mean temperature was associated with a 3.8 and 5.0% rise in suicide and violent suicide respectively. Suicide increased by 46.9% during the 1995 heatwave, whereas no change was seen during the 2003 heat wave.ConclusionsThere is increased risk of suicide during hot weather.

scholarly journals The time series regression analysis in evaluating the economic impact of COVID-19 cases in Indonesia

2021 ◽  
Vol 16 (3) ◽  
pp. 197-210
Author(s):  
Utriweni Mukhaiyar ◽  
Devina Widyanti ◽  
Sandy Vantika
Keyword(s):  
Time Series ◽  
Exchange Rate ◽  
Moving Average ◽  
Autoregressive Moving Average ◽  
Transfer Function Model ◽  
Function Model ◽  
Time Series Regression ◽  
Vector Autoregressive ◽  
Daily Data ◽  
The Impact

This study aims to determine the impact of COVID-19 cases in Indonesia on the USD/IDR exchange rate using the Transfer Function Model and Vector Autoregressive Moving-Average with Exogenous Regressors (VARMAX) Model. This paper uses daily data on the COVID-19 case in Indonesia, the USD/IDR exchange rate, and the IDX Composite period from 1 March to 29 June 2020. The analysis shows: (1) the higher the increase of the number of COVID-19 cases in Indonesia will significantly weaken the USD/IDR exchange rate, (2) an increase of 1% in the number of COVID-19 cases in Indonesia six days ago will weaken the USD/IDR exchange rate by 0.003%, (3) an increase of 1% in the number of COVID-19 cases in Indonesia seven days ago will weaken the USD/IDR exchange rate by 0.17%, and (4) an increase of 1% in the number of COVID-19 cases in Indonesia eight days ago will weaken the USD/IDR exchange rate by 0.24%.

The effects of the lower ignition propensity cigarettes standard in Estonia: time-series analysis

2017 ◽  
Vol 24 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Indrek Saar
Keyword(s):  
European Union ◽  
Time Series ◽  
Fire Safety ◽  
The European Union ◽  
Time Series Regression ◽  
Absolute Level ◽  
Counterfactual Models ◽  
Dynamic Time ◽  
The Impact ◽  
Ignition Propensity

BackgroundIn 2011, the lower ignition propensity (LIP) standard for cigarettes was implemented in the European Union. Evidence about the impact of that safety measure is scarce.ObjectiveThe aim of this paper is to examine the effects of the LIP standard on fire safety in Estonia.MethodsThe absolute level of smoking-related fire incidents and related deaths was modelled using dynamic time-series regression analysis. The data about house fire incidents for the 2007–2013 period were obtained from the Estonian Rescue Board.ResultsImplementation of the LIP standard has reduced the monthly level of smoking-related fires by 6.2 (p<0.01, SE=1.95) incidents and by 26% (p<0.01, SE=9%) when estimated on the log scale. Slightly weaker evidence was found about the fatality reduction effects of the LIP regulation. All results were confirmed through counterfactual models for non-smoking-related fire incidents and deaths.ConclusionsThis paper indicates that implementation of the LIP cigarettes standard has improved fire safety in Estonia.

The Impact of American College of Cardiology Chest Pain Center Accreditation on Guideline Recommended Acute Myocardial Infarction Management

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
W. Frank Peacock ◽  
Phillip D. Levy ◽  
Deborah B. Diercks ◽  
Shuang Li ◽  
James McCord ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Chest Pain ◽  
Pain Center ◽  
The Impact

The Pied Piper of Crime in America: An Analysis of the Presidents’ and Public’s Agenda on Crime

2002 ◽  
Vol 13 (2) ◽  
pp. 139-155 ◽  
Author(s):  
Willard M. Oliver
Keyword(s):  
Time Series ◽  
Regression Analysis ◽  
Public Opinion ◽  
Presidential Rhetoric ◽  
Policy Area ◽  
Time Series Regression ◽  
Public Response ◽  
The Public ◽  
State Of The Union ◽  
The Impact

The theory of presidential influence over public opinion is used to predict the impact of presidential rhetoric on crime over the public’s concern for crime being “the most important problem facing the nation.” It is hypothesized that the more attention presidents give to the policy area of crime in the their State of the Union Addresses, the more concerned the public becomes with crime. Utilizing a time-series regression analysis of data collected from a content analysis of presidents’ State of the Union addresses on the Gallup Poll’s Most Important Problem series from 1946 to 1996, the analysis demonstrates that presidential mention of crime seems to elicit a public response, thus influencing public opinion of crime with a decay effect of approximately 1 year.

When the President Speaks…

2011 ◽  
Vol 36 (4) ◽  
pp. 456-469 ◽  
Author(s):  
Willard M. Oliver ◽  
Joshua Hill ◽  
Nancy E. Marion
Keyword(s):  
Time Series ◽  
Drug Use ◽  
Illicit Drugs ◽  
Presidential Rhetoric ◽  
Public Concern ◽  
Policy Area ◽  
Time Series Regression ◽  
The Public ◽  
State Of The Union ◽  
The Impact

The theory of presidential influence over public opinion is used to predict the impact of presidential rhetoric on the public’s concern regarding drug use as “the most important problem (MIP) facing the nation.” It is hypothesized that the more attention presidents give to the policy area of drugs in their state of the union (SOTU) addresses, the more concerned the public becomes with drug use. Using a time-series regression analysis of data collected from a content analysis of presidents’SOTU speeches regressed on the Gallup Poll’s MIP series from 1946 to 2010, the findings suggest that presidential mentions of drugs in the SOTU addresses influence public concern for illicit drugs in America.

scholarly journals Exploring the Delay in the Informed Consent Procedures of Patients with ST-Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention: Is It Worth the Wait?

2021 ◽  
Author(s):  
Mailikezhati Maimaitiming ◽  
Junxiong Ma ◽  
Xuejie Dong ◽  
Shuduo Zhou ◽  
Na Li ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Chest Pain ◽  
Informed Consent ◽  
Hospital Mortality ◽  
Delay Time ◽  
Coronary Intervention ◽  
Percutaneous Coronary ◽  
St Elevation ◽  
Door To Balloon

Abstract Background Failure to achieve timely informed consent is the most important predictors of prolonged in-hospital delay in China. It is critically serious among patients with ST-elevation myocardial infarction (STEMI), which is the deadliest and most time-sensitive acute cardiac event. Informed consent procedure always begins on ambulance before door still does not complete yet after the catheterization laboratory is ready for percutaneous coronary intervention (PCI), which results in delayed treatment and poor clinical outcomes. This study aimed to investigate the factors associated with informed consent delay in patients with STEMI undergoing PCI, and its influence on in-hospital mortality. Methods We conducted a national-representative retrospective cohort study, drawing patient data reported by hospital-based chest pain centers, of admission between January 2016 and June 2019. Using generalized linear mixed models and negative binomial regression, we estimated factors independently predicting informed consent delay time. The associations of informed consent delay time, door-to-balloon (D2B) time and in-hospital mortality were analyzed by logistic regression, adjusted for patient characteristics. Results A total of 263,219 patients were enrolled in the analysis. Informed consent delay occurred in 44.7% (117,672) patients, of whom the median delayed time was 18.6 minutes (SD = 22.2). Patients with sustainable chest pain (RR: 1.032, p = 0.010), intermittent chest pain (RR: 1.083, p < 0.001), and dyspnea (RR: 1.096, p = 0.001) were more likely to delay informed consent. Among transfer modes, walk-in (RR: 1.165, p < 0.001), transfer-in (RR: 1.122, p < 0.001), in-hospital onset (RR: 1.248, p < 0.001) significantly correlated with extended informed consent delay time. The age of 35–64 years (RR: 0.941, p = 0.010) had a negative association with informed consent delay time. Informed consent delay was significantly associated with prolonged D2B time (OR: 1.148, p < 0.001), whereas there was no significant association between informed consent delay and in-hospital mortality. Conclusion Informed consent delay provokes prolongation of door-to-balloon time, which contributes to in-hospital delay that endangers STEMI patients. For better management of STEMI patients in emergent situations, it is essential to reduce the time of informed consent obtaining through effective patient-physician communication, and care coordination within and between hospitals. Trial registration: Retrospectively registered.

The Determinants of Municipal Debt Policy: A Pooled Time-Series Analysis

1998 ◽  
Vol 16 (2) ◽  
pp. 211-224 ◽  
Author(s):  
R A Cropf ◽  
G D Wendel
Keyword(s):  
Time Series ◽  
Time Series Regression ◽  
General Obligation ◽  
Local Officials ◽  
Municipal Debt ◽  
General Obligation Debt ◽  
Pooled Time Series ◽  
The Impact ◽  
Us Cities ◽  
Debt Policy

Cities have started to rely more on debt in recent decades, in large part in response to changes occurring externally. In this paper the authors analyze the impact of important social, political, and economic factors on municipal debt behavior. They examine the 42 largest US cities from 1980 to 1990, using a pooled time-series regression model. It was found that, generally speaking, these factors had the effect of increasing cities' reliance on revenue debt, which is less accountable to the voters than full-faith and credit debt. It is difficult to say whether local officials have consciously pursued a policy of insulating municipal debt decisions from the voters. However, it is clear that these officials are responding to environmental cues that lead them to prefer revenue debt over general-obligation debt by a large margin. Recent research has shown that cities have historically pursued a ‘politics of circumvention’. With the demand for debt increasing as other means for financing local services are constrained the effects on the polity of these preferences warrant serious attention.

Evaluation of the CAN SPAM Act: Testing Deterrence and Other Influences of E-mail Spammer Legal Compliance Over Time

2014 ◽  
Vol 33 (4) ◽  
pp. 440-458 ◽  
Author(s):  
Alex C. Kigerl
Keyword(s):  
Time Series ◽  
Federal Legislation ◽  
Legal Compliance ◽  
Time Series Regression ◽  
Can Spam Act ◽  
The Impact ◽  
E Mail ◽  
Over Time

E-mail spam has been growing since its inception. The Controlling the Assault of Non-Solicited Pornography and Marketing Act (CAN SPAM Act) is U.S. federal legislation that was passed in response to the growing spam problem. A series of evaluations followed after the Act, most of which reported that compliance with the Act’s requirements among spammers had not been affected. However, none of these evaluations used methods that were sufficiently rigorous, failing to capture the continuous nature of CAN SPAM Act’s enforcement, using a limited number of measures of noncompliance, and ignoring a variety of possible spurious influences. This research addresses all of these limitations by analyzing a sample of 5,490,905 spam e-mails sent between 1998 and 2013. Ten measures of spammer compliance with the CAN SPAM Act were operationalized to test the impact the Act had. Thirteen measures of CAN SPAM Act enforcement were coded from news articles and included in a time-series regression. Findings suggest that the Act may in fact be a deterrent, but in such a way as to increase CAN SPAM Act violations of header forgery as a precaution against being caught.

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