scholarly journals Blood pressure and hypertension prevalence among oldest-old in China for 16 year: based on CLHLS

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Jiajun Du ◽  
Guoning Zhu ◽  
Yanhong Yue ◽  
Miao Liu ◽  
Yao He

Abstract Background There were little national data on hypertension based on the oldest-old, and lack of information on chronological changes. This study aimed to describe trends of blood pressure (BP) levels and hypertension prevalence for the past 16 years among the oldest-old in China. Methods All the oldest-old who had participated in the Chinese Longitudinal Healthy Longevity Survey (CLHLS) 1998 to 2014 with information about BP levels and hypertension were included in the analysis. Results There was fluctuation over the past 16 years for both SBP and DBP levels. The mean SBP level decreased from 148.4 ± 24.4 mmHg in 1998 to 130.8 ± 18.7 mmHg in 2005, and then increased to 139.7 ± 22.0 mmHg in 2014. The mean DBP level decreased from 84.3 ± 13.4 mmHg in 1998 to 78.9 ± 11.7 mmHg in 2008, and then increased to 79.7 ± 11.8 mmHg in 2014. The hypertension prevalence increased from 43.1 to 56.5% for the 16 years. The prevalence of isolated systolic hypertension was lowest in 2002–2005 (14.3%), and then increased to 30.7% in 2014. Multivariate logistic regression showed that older age, lower education and economic level, without health insurance were associated with higher hypertension prevalence. Conclusions There was a significant increase in hypertension prevalence among the Chinese oldest-old from 1998 to 2014. Greater efforts are needed for hypertension prevention among this specific population.

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Joshua R Thomas ◽  
Ricky T Munoz ◽  
Mark D Fox ◽  
Angela T Yetman

Background: Cardiovascular risk factors (CRFs) are poorly defined among the population of adults with congenital heart disease. In particular, the prevalence of pre-hypertension (pre-HTN) and hypertension (HTN) are currently unknown. Objective: To determine the prevalence of pre-HTN and HTN among adults with congenital heart disease; and to assess HTN control rates among different clinic types. Methods: A retrospective analysis of a cohort of adults with congenital heart disease (CHD) was conducted. Data regarding CHD patients' blood pressure (BP), medications, and provider specialty were analyzed. Results: The cohort consisted of 971 patients. The mean age was 30.4 years (SD = 10.4), with 51% male. Thirty-two percent had HTN (n = 304). There was no statistically significant difference in the prevalence of Pre-HTN and HTN by clinic type (i.e. specialty vs. non-specialty)( p = .225, p= .633 respectively). However, a statistically significant association exists between clinic type and HTN control rates χ 2 (1) = 3.185, p = .07 (Table 1). Those receiving care from a specialty clinic are 1.6 times more likely to have controlled HTN. Conclusions: Pre-HTN and HTN are common among adults with congenital heart disease. These CRFs are better managed in specialty clinics devoted to this population.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hui Gao ◽  
Kan Wang ◽  
Fariba Ahmadizar ◽  
Wensui Zhao ◽  
Yu Jiang ◽  
...  

Abstract Background Blood pressure targets for oldest-old people have been long debated due to the concern that more stringent targets are associated with increased mortality. We aimed to investigate the association between changes of late-life systolic blood pressure (SBP), mean SBP and SBP variability (SBPV), and all-cause mortality in oldest-old. Methods Based on the community-based Chinese Longitudinal Healthy Longevity Survey with follow-up conducted in the 3-year interval, we assembled a retrospective cohort of 6639 participants ≥ 80 years with available blood pressure measurements at baseline and second wave. The primary exposures were mean SBP and SBPV (defined as the annual difference in SBP divided by mean SBP) measured between baseline and second wave. The primary outcome was all-cause mortality assessed from the second wave. Results During 21443.1 person-years of follow-up, 4622 death was recorded. U-shaped associations of mortality with mean SBP and SBPV were identified; the value of 137 mmHg and 4.0 %/year conferred the minimum mortality risk, respectively. The associations of a larger SBPV with an increased mortality risk were observed for both rises and large falls in SBP. The hazard ratio was 1.11 (comparing lowest versus middle quintile; 95 % CI: 1.01, 1.22) with large falls in SBPV and 1.08 (comparing highest versus middle quintile; 95 % CI: 0.98, 1.18) with large rises in SBPV. Conclusions U-shaped associations between late-life SBP and SBPV and all-cause mortality were found. Our study suggests that a stable SBP level in the middle range is related to lower mortality risk in the oldest-old.


2019 ◽  
Author(s):  
Jiajun Du ◽  
Guoning Zhu ◽  
Jianhua Wang ◽  
Miao Liu ◽  
Yao He

2020 ◽  
Vol 110 (10) ◽  
pp. 1535-1537
Author(s):  
Qiushi Feng ◽  
Joelle H. Fong ◽  
Wei Zhang ◽  
Changxi Liu ◽  
Huashuai Chen

Objectives. To examine the trends of leisure activity engagement among the oldest old in China for the past 2 decades. Methods. Our panel data came from the Chinese Longitudinal Healthy Longevity Survey, which systematically asked respondents about their current participation in leisure activities over a 20-year period. The final sample contained 66 789 interviews from 1998 to 2018. We applied generalized estimating equations regression models in our analysis. Results. Compared with 1998, odds ratios of television watching among Chinese oldest old individuals increased by about 2 to 3 times in 2018. Meanwhile, the odds ratio of exercise declined by 24%, mostly in men; playing cards and mah-jongg declined by about 30% for men. Results also showed that reading became less popular in the oldest old, and Chinese women tended to do more housework than before. Conclusions. Our findings indicated that Chinese oldest old persons have become more sedentary and solitary in the past 2 decades. The negative trend in leisure activity engagement among the elderly Chinese population warrants policy attention, and the urgent development of public health interventions is required to reverse such trends.


2020 ◽  
Vol 3 (1) ◽  
pp. 14-24
Author(s):  
Zehui Jiang ◽  
Jun Zhang ◽  
Junyong Wang ◽  
Junshan Li ◽  
Meihui He ◽  
...  

Objective To understand the present status of high blood pressure in Jiangxi adults including the prevalence rate, overall awareness, and hypertension treatment. Methods a total of 7,200 adult participants (over 18 years old) lived in Jiangxi were recruited using a stratified sampling method. Blood pressure was measured for all the participants and a questionnaire survey was conducted. A 24-hour urine sample was also collected to understand urine sodium and potassium levels. Results Our findings revealed that the measured systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 125.9 mmHg (95% CI, 124.85-126.95) and 79.2 mm Hg (95% CI, 78.15-80.25). The prevalence of hypertension among the enrolled adults was 27.43% (95% CI, 26.38%–28.48%). Among the affected participants, less than 30% of them (95% CI) were aware of their hypertension condition, and only 28.56% (95% CI) were under anti-hypertension medications. The mean salt intake converted from urinary sodium was 10.92±4.07 g and the mean±SD of 24-h urinary sodium and potassium excretion were 185.51±65.44 mmol and 25.98±9.16 mmol, respectively. The high-salt condiments was determined to be the main source of sodium in the region. Conclusion Findings from this study form the baseline information to understand the hypertension condition in the region and indicate a possible solution for hypertension prevention through avoiding high-salt condiments.


1984 ◽  
Vol 4 (4) ◽  
pp. 221-223 ◽  
Author(s):  
Andrzej Breborowicz ◽  
Jan Knapowski

A local anesthetic -bupivacaine was used in concentration 0.25 mmol/l in the dialysis fluid during peritoneal dialysis in rabbits. Bupivacaine increased the mean peritoneal clearance of urea by 33% and of inulin by 53%. The effect of the anesthetic persisted during next exchanges, performed without the drug. Bupivacaine given intraperitoneally, did not decrease blood pressure. Peritoneal dialysis is used widely for treatment of renal failure (1). During the last few years, many attempts have been made to find a substance, which would increase the efficiency of peritoneal dialysis (2, 4). In the past we observed that procaine added to the fluid augments peritoneal solute clearance (5). Local anesthetics in the peritoneal cavity influence both the mesothelium and the vascular system. In the present study we used bupivacaine a long-acting, tissue-bound local anesthetic as the adjunct during peritoneal dialysis in rabbits.


2021 ◽  
Author(s):  
Hui Gao ◽  
Kan Wang ◽  
Fariba Ahmadizar ◽  
Wensui Zhao ◽  
Yu Jiang ◽  
...  

Abstract Background: Blood pressure targets for oldest-old people have been long debated due to the concern that more stringent targets are associated with increased mortality. We aimed to investigate the association between late-life systolic blood pressure control (mean SBP) and variability (SBPV) and mortality in oldest-old people.Methods: Based on the community-based Chinese Longitudinal Healthy Longevity Survey with follow-up conducted in the 3-year interval, we assembled a retrospective cohort of 5951 participants ≥80 years with available blood pressure measurements at baseline and second wave. The primary exposures were mean SBP and SBPV (defined as the annual difference in SBP divided by mean SBP) measured between baseline and second wave. The primary outcome was 3-year all-cause mortality assessed between the second and third waves.Results: During 21733.9 person-years of follow-up, 4290 death was recorded. U-shaped associations of mortality with mean SBP and SBPV were identified; the value of 137 mmHg and 2.3 %/year conferred the minimum mortality risk, respectively. The associations of a larger SBPV with an increased mortality risk were observed for both rises and large falls in SBP. The hazard ratio was 1.16 (comparing lowest versus middle quintile; 95% CI: 1.06, 1.28) with large falls in SBPV and 1.10 (comparing highest versus middle quintile; 95% CI: 1.00, 1.21) with large rises in SBPV.Conclusions: U-shaped associations between late-life SBP and SBPV and all-cause mortality were found. Our study suggests that a stable SBP level in the middle range decreases the risk of mortality in the oldest-old people.


2021 ◽  
Author(s):  
Huaze Ye ◽  
Jie Tang ◽  
Leiqin Luo ◽  
Tianjian Yang ◽  
Kedi Fan ◽  
...  

Abstract We aimed to examine PM2.5 exposure, blood pressure (SBP and DBP) measurement, hypertension risk factors and to assess the association between PM2.5 exposure and hypertension among young adults. The mean SBP was 117.78 mmHg, with 11.22% high-normal blood pressure (prehypertension) and 2.51% hypertension (≥ 140 mmHg). DBP was 75.48 mmHg with 26.37% prehypertension and 4.53% hypertension (≥ 90 mmHg). The median PM2.5 in the past year was 31.79 µg/m3, with highest in winter (49.33 µg/m3), followed by spring (37.34 µg/m3), autumn (29.64 µg/m3) and summer (24.33 µg/m3). Blood pressure was positively correlated with age, height, weight, BMI, daily smoking, alcohol consumption, mental stress and stay-up in the past 1 year. After adjustment for the covariates, each 10 µg/m3 increase in PM2.5 was associated with SBP (Day 1 = 1.07 mmHg, Day 3 = 1.25 mmHg, Day 5 = 1.01 mmHg) and DBP (Day 1 = 1.06 mmHg, Day 3 = 1.28 mmHg, Day 5 = 1.29 mmHg, Day 15 = 0.87 mmHg, Day 30 = 0.56 mmHg). Exposure in winter was associated with 1.17 mmHg increase in SBP. Logistic models showed for every 1 µg/m3 increase of PM2.5, SBP in Day 1 and Day 5 was increased by 6% and 4%, and DPB by 3% and 16%, respectively. SBP was increased by 13% in spring and 7% in winter, and DBP was increased by 12% in winter. Our data suggest a certain prevalence of pre- or hypertension among young population, which is associated with short-term fluctuation and season-specific exposure of PM2.5.


2019 ◽  
Vol 1 (7) ◽  
pp. 29-32 ◽  
Author(s):  
L. S. Kruglova ◽  
E. M. Gensler

Over the past decades, the first breakthrough milestone in the treatment of severe forms of atopic dermatitis (AD) has been targeted therapy aimed at inhibiting IL-4 and IL-13. This was made possible thanks to advances in the understanding of the pathogenesis of AD, the driver of which is the Th2-type immune response, which also underlies such manifestations of atopy as bronchial asthma, allergic rhinitis, and polynosis. In the case of the Th2-type immune response, cytokines IL-4 and IL-13 are secreted, which are the main promoters of the inflammatory response in AD. Inhibition of IL-4 and IL-13 leads to the prevention of inflammation and is an effective approach to therapy. The use of therapy aimed at inhibition of cytokines allows you to effectively cope with the manifestations of severe and moderately severe blood pressure.


2017 ◽  
pp. 88-92
Author(s):  
Van Hien Pham ◽  
Huu Vu Quang Nguyen ◽  
Tam Vo

Background: Cardiovascular diseases are the leading cause of death in patients with chronic renal failure. When a patient undergoes dialysis, making AVF or AVG causes cardiovascular events. Understanding the relationship between complications: hypertension, heart failure, AVF or AVG (formation time, position, diameter) helps us monitor, detect, prevent and treatment of complications to limit the risk of death in patients with dialysis. Objective: Relationship between cardiovascular diseases and anatomosis of arteriovenous fistular in patients with regularly hemodialysis at Cho Ray Hospital. Methods: A cross-sectional study was conducted at Cho Ray Hospital from 2015 to 2016. The survey some cardiovascular diseases are done by clinical examination, tests for diagnostic imaging such as X-ray, electrocardiogram and echocardiogram: heart and diameter of anastomosis AVF, AVG. Results: The study population included 303 patients with chronic renal failure who were dialysis. Of which, patients aged 25-45 accounted for the highest proportion (43.9%). The proportion of male and female patients was similar (48.5% and 51.5% respectively). The mean value of systolic blood pressure on patients made AVF, AVG less than 12 months is higher than patients made AVF, AVG over 12 months, and there is negative correlation (r = -0.43) between AVF, AVG and systolic blood pressure (p <0.05). The mean value of diastolic blood pressure on patients made AVF, AVG less than 12 months is lower than patients made AVF, AVG over 12 months, and and there is positive correlation (r = -0.43) between AVF, AVG and diastolic blood pressure (p <0.05) (p <0.05). The prevalence of patients with heart failure made AVF, AVG over 12 months is higher than that of the under 12 months group, there is a negative correlation (r = - 0.43) between AVF, AVG diameter and EF index (p <0.05). Conclusion: It is important to note the diameter of anastomosis AVF, AVG in patients with chronic renal failure dialysis to limit cardiovascular complications, especially heart failure. Key words: Chronic kidney disease, hemodialysis.


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