scholarly journals Seroprevalence of mucosal and cutaneous human papillomavirus (HPV) types among children and adolescents in the general population in Germany

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Anna Loenenbach ◽  
Michael Pawlita ◽  
Tim Waterboer ◽  
Thomas Harder ◽  
Christina Poethko-Müller ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Adult Population ◽  
Hpv Vaccination ◽  
Serological Response ◽  
Serum Samples ◽  
Representative Data ◽  
Hpv Types ◽  
Nationally Representative ◽  
The Impact ◽  
Hpv 1

Abstract Background In Germany, HPV vaccination of adolescent girls was introduced in 2007. Nationally representative data on the distribution of vaccine-relevant HPV types in the pre-vaccination era are, however, only available for the adult population. To obtain data in children and adolescents, we assessed the prevalence and determinants of serological response to 16 different HPV types in a representative sample of 12,257 boys and girls aged 1–17 years living in Germany in 2003–2005. Methods Serum samples were tested for antibodies to nine mucosal and seven cutaneous HPV types. The samples had been collected during the nationally representative German Health Interview and Examination Survey for Children and Adolescents in 2003–2006. We calculated age- and gender-specific HPV seroprevalence. We used multivariable regression models to identify associations between demographic and behavioral characteristics and HPV seropositivity. Results We found low but non-zero seroprevalence for the majority of tested HPV types among children and adolescents in Germany. The overall seroprevalence of HPV-16 was 2.6%, with slightly higher values in adolescents. Seroprevalence of all mucosal types but HPV-6 ranged from 0.6% for HPV-33, to 6.4% for HPV-31 and did not differ by gender. We found high overall seroprevalence for HPV-6 with 24.8%. Cutaneous HPV type seroprevalence ranged from 4.0% for HPV-38 to 31.7% for HPV-1. In the majority of cutaneous types, seroprevalence did not differ between boys and girls, but increased sharply with age, (e.g., HPV-1 from 1.5% in 1–3-years-old to 45.1% in 10–11-years-old). Associations between behavioral factors and type-specific HPV prevalence were determined to be heterogeneous. Conclusions We report the first nationally representative data of naturally acquired HPV antibody reactivity in the pre-HPV-vaccination era among children and adolescents living in Germany. These data can be used as baseline estimates for evaluating the impact of the current HPV vaccination strategy targeting 9–14-years-old boys and girls.

The impact of investment on drinking water quality in rural China

2017 ◽  
Vol 9 (2) ◽  
pp. 255-269
Author(s):  
Ai Yue ◽  
Yaojiang Shi ◽  
Renfu Luo ◽  
Linxiu Zhang ◽  
Natalie Johnson ◽  
...  
Keyword(s):  
Water Quality ◽  
Drinking Water ◽  
Rural Areas ◽  
Tap Water ◽  
Rural China ◽  
Ordinary Least Squares ◽  
Content Type ◽  
Representative Data ◽  
Nationally Representative ◽  
The Impact

Purpose Although access to safe drinking water is one of the most important health-related infrastructure programs in the world, drinking water remains a large problem in China today, especially in rural areas. Despite increased government investment in water resource protection and management, there is still an absence of academic studies that are able to document what path the investment has taken and whether it has had any tangible impact. The purpose of this paper is to analyze the impact of drinking water investment on drinking water in China. Design/methodology/approach The authors make use of nationally representative data from 2005 and 2012 to measure the impact of drinking water investment among 2,028 rural households in 101 villages across five provinces. Both ordinary least squares regression and probit regression are used to analyze the correlates and the impact of drinking water investment. Findings The authors demonstrate that water quality was likely a significant problem in 2004 but that China’s investment into drinking water appears to have resulted in initial improvements during the study period. The authors show that the most significant change came about in terms of hardware: villages that received more drinking water investment now have more piped tap water and more access to water treatment infrastructure (disinfecting and filtering facilities). High rates of rural resident satisfaction with drinking water suggest the effects of drinking water investment are being felt at the village level. Originality/value To the authors’ knowledge, this is the first empirical study on drinking water investment over time in rural China using nationally representative data.

scholarly journals The measurement by serological means of the impact of the Hong Kong/68 influenza virus on a population

1972 ◽  
Vol 6 (1) ◽  
pp. 85-88 ◽  
Author(s):  
José Alberto N. Candeias ◽  
Marguerite S. Pereira
Keyword(s):  
Influenza Virus ◽  
Hong Kong ◽  
Adult Population ◽  
Haemagglutination Inhibition ◽  
Sharp Decrease ◽  
Sao Paulo ◽  
First Year ◽  
São Paulo ◽  
Serum Samples ◽  
The Impact

In order to obtain evidence on the size of the impact of the Hong Kong/68 variant of influenza A2 virus on the population of São Paulo, Brazil, serum samples taken in 1967 before this variant appeared and during successive years after it appeared were examined for their antibody content. Haemagglutination-inhibition tests performed on a total of 2726 serum samples from adults showed a sharp decrease in 1969 of the proportion of sera without antibody to the Hong Kong/68 variant and a corresponding mercase in the proportion with high titres. It was concluded that about three-quarters of the adult population became infected at some time after the variant appeared, the majority in the first year of prevalence.

scholarly journals Epidemiology of Traumatic Dental Injuries in Children and Adolescents - A Review

2021 ◽  
Vol 10 (22) ◽  
pp. 1709-1714
Author(s):  
Amitha M. Hegde ◽  
Sonali Sodhi
Keyword(s):  
Risk Factors ◽  
Children And Adolescents ◽  
Adult Population ◽  
Age Groups ◽  
Dental Trauma ◽  
Public Health Importance ◽  
Traumatic Dental Injuries ◽  
Dental Injuries ◽  
The Impact ◽  
Incidence Prevalence

BACKGROUND Every child is prone to traumatic injuries, the impact of these injuries is directly related to the intensity, force and direction from which the trauma is inflicted. Trauma to the oral cavity is rather more common in children and adolescents as compared to the adult population. Since dental trauma is unanticipated, instantaneous and accidental, it often needs immediate and emergency management, depending on the severity of the injury. Thus, it is tremendously important to understand the patterns of incidence, prevalence, aetiology and risk factors associated with traumatic dental injuries. This article aims to review the epidemiology, incidence, prevalence, aetiology, risk factors and current trends of traumatic dental injuries in children and adolescents. The aetiologic factors vary among countries and within different age groups. The risk of sustaining traumatic dental injuries is generally dependent on several elements like age, circumstance, geography, behaviour and culture. Changing lifestyle especially related to urbanisation has led to amplification in the prevalence of dental trauma. The emergence of new trends in the modern society has led to creation of newer patterns and risk factors for the same. Traumatic dental injuries are linked to biological, social, financial and psychological factors. This article provides an overview on the epidemiology of traumatic dental injuries. This topic is of public health importance. This review is important to understand the underlying risk factors in order to reduce the prevalence and incidence of dental trauma. Educating the public regarding this will reduce the incidence of dental trauma. KEY WORDS Dental Trauma, Aetiology, Risk Factors, Epidemiology, Prevalence, Prevention, Paediatric Dentistry

scholarly journals Victimization and PTSD in A Rural Kenyan Youth Sample

2012 ◽  
Vol 8 (1) ◽  
pp. 91-101 ◽  
Author(s):  
Sidsel H Karsberg ◽  
Ask Elklit
Keyword(s):  
Children And Adolescents ◽  
Ethnic Diversity ◽  
Clinical Studies ◽  
Epidemiological Studies ◽  
Treatment Programs ◽  
Post Traumatic Stress ◽  
Potentially Traumatic Events ◽  
Post Traumatic ◽  
Nationally Representative ◽  
The Impact

Within the last ten years, there has been a growing number of epidemiological studies, examining the effect of trauma exposure in children and adolescents. Although studies concerning Post-traumatic Stress Disorder (PTSD) have been conducted in a wide array of different cultural contexts [1], the knowledge on traumatization and development of PTSD is still limited [2]. Most studies conducted are clinical studies, which deal with subjects that have already been traumatized or affected by specific single events such as war [3], natural disasters [1], serious accidents [4] or physical/sexual abuse [5-7]. Though research indicates that adolescents are very vulnerable to the exposure of Potentially Traumatic Events (PTEs) [8], studies targeting non-clinical youth populations and the impact of their life experiences are very few. With the increasing ethnic diversity of populations worldwide, it is of particular interest to compare the prevalence of exposure and PTSD in children and adolescents of different ethnic backgrounds. When designing preventive interventions and treatment programs for youth suffering from PTSD it is crucial to understand the complex interaction of variables behind the disorder. Differences in prevalence of exposure, PTSD and demographic variables between ethnicities may reveal some important clues to the etiology of the disease. The present study replicated six previous non-clinical studies which were designed to provide epidemiological information about exposure to PTEs, and the prevalence of PTSD among adolescents (see Table 1). The six studies were conducted in different countries and were very similar in their research methods and samples. The studies have been conducted in four European countries: Denmark [9], Iceland, [10], Lithuania [11], and the Faroe Islands [2], as well as in two Asian countries: Israel [12], and India [13] of which the four first samples were nationally representative.

COVID-19 Vaccines for Children and Adolescents in Africa: Aligning our Priorities to Situational Realities (Preprint)

2021 ◽  
Author(s):  
Kaymarlin Govender
Keyword(s):  
Children And Adolescents ◽  
Vaccine Coverage ◽  
Adult Population ◽  
High Income ◽  
Vaccine Hesitancy ◽  
African Continent ◽  
Middle Income ◽  
Health Crisis ◽  
Vaccines For Children ◽  
The Impact

UNSTRUCTURED The impact of the COVID-19 pandemic in Africa is unparalleled. Most countries within Africa are facing major challenges vaccinating their populations. Lack of sufficient doses of COVID-19 vaccines, weaknesses in health infrastructure, and vaccine hesitancy are contributing to low vaccination rates among the adult population on the continent. In contrast, most high-income countries and some middle-income countries have already vaccinated more than half of their adult population and have started vaccinating children and adolescents (CA). Without sufficient COVID-19 vaccine coverage on the African continent, the prolonged social, economic, and health impacts of this public health crisis are likely to exacerbate pre-existing social-structural issues in this part of the world. In this paper, we highlight trends in SARS-CoV-2 infections among CA, compare COVID-19 vaccination patterns in Africa to high income countries, and discuss some of the benefits, challenges, and unknowns associated with vaccinating CA for COVID-19. In light of ongoing COVID-19 vaccine supply challenges and the slow progress that the African continent is making towards vaccinating the adult population, we suggest that the immediate priority for Africa is to accelerate COVID-19 vaccinations among the adult population and vulnerable CA (i.e., those who are immunocompromised and/or living with comorbidities). Accelerating the rollout of COVID-19 vaccines and rapidly achieving high levels of vaccination coverage in the adult population will free up capacity to vaccinate CA sooner rather than later.

scholarly journals Food Sustainability Knowledge and Attitudes in the Spanish Adult Population: A Cross-Sectional Study

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3154
Author(s):  
Ángela García-González ◽  
María Achón ◽  
Alejandra Carretero Krug ◽  
Gregorio Varela-Moreiras ◽  
Elena Alonso-Aperte
Keyword(s):  
Environmental Impact ◽  
Food Systems ◽  
Adult Population ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Sustainable Food Systems ◽  
Sustainable Food ◽  
Carbon Footprints ◽  
Nationally Representative ◽  
The Impact

Moving towards sustainable food systems and food consumption are proposed as strategies to reduce environmental impact. However, these strategies require joint action between different stakeholders, including the general population’s knowledge and perception, as final consumers. To assess the knowledge and awareness on food sustainability and environmental impact concepts in a representative sample of Spanish adult population, we conducted a cross-sectional, nationally representative telephone survey. After random selection, 2052 respondents aged ≥18 years (57% woman and 43% men) participated. A questionnaire was specifically designed for the research. Participants showed a good attitude towards sustainable diets, which were described as healthy by 40% of the population. Most of the responders (>70%), did not well understand ecological and carbon footprints, and green and blue water concepts. Men declared a higher understanding of sustainability concepts, as compared to women. More than 50% of the population misunderstood the impact of meat and derivatives production on sustainability, and 70% perceived the same for fish and dairy products. Women were more prone to pay more money to afford a sustainable diet than men were. In conclusion, although consumers show a positive attitude towards sustainability, important misconceptions remain, and thus require intervention through education, information, and motivation.

scholarly journals Context, design and conduct of the longitudinal COVID-19 Psychological Research Consortium (C19PRC) Study – Wave 3

2020 ◽  
Author(s):  
Orla McBride ◽  
Sarah Butter ◽  
Jamie Murphy ◽  
Mark Shevlin ◽  
Todd K. Hartman ◽  
...  
Keyword(s):  
Adult Population ◽  
Psychological Research ◽  
Study Data ◽  
Household Composition ◽  
Cross Sectional ◽  
The Cross ◽  
Nationally Representative ◽  
Research Consortium ◽  
The Uk ◽  
The Impact

Objectives: The COVID-19 Psychological Research Consortium (C19PRC) Study aims to assess the impact of the COVID-19 pandemic in the adult population in multiple countries. This paper describes the execution of the third wave of the UK survey (the ‘parent’ strand of the Consortium) during July-August 2020. Methods: Adults (N=2025) who previously participated in the baseline and/or the first follow-up surveys were reinvited to participate in this survey, which assessed: (1) COVID-19 related knowledge, attitudes, and behaviours; (2) the occurrence of common mental health disorders; as well as the role of (3) psychological factors and (4) social and political attitudes, in influencing the public’s response to the pandemic. Weights were calculated using a survey raking algorithm to ensure that the cross-sectional sample is nationally representative in terms of gender, age, household income, household composition, and urbanicity. Results: 1166 adults (57.6% of baseline participants) were successfully recontacted and provided full interviews at Wave 3. As expected, the raking procedure successfully re-balanced the cross-sectional sample to within 1% of population estimates across the selected socio-demographic characteristics. Conclusion: This paper outlines the growing strength of the C19PRC Study data to facilitate and stimulate interdisciplinary research addressing important public health questions relating to the COVID-19 pandemic.

scholarly journals Human Papillomavirus Oral- and Sero- Positivity in Fanconi Anemia

Cancers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1368
Author(s):  
Sharon L. Sauter ◽  
Xue Zhang ◽  
Lindsey Romick-Rosendale ◽  
Susanne I. Wells ◽  
Kasiani C. Myers ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Fanconi Anemia ◽  
Hpv Vaccination ◽  
Serum Samples ◽  
Serological Studies ◽  
Oral Hpv ◽  
Hpv Types ◽  
Family Advocacy

High-risk human papillomavirus (HPV) is prevalent and known to cause 5% of all cancers worldwide. The rare, cancer prone Fanconi anemia (FA) population is characterized by a predisposition to both head and neck squamous cell carcinomas and gynecological cancers, but the role of HPV in these cancers remains unclear. Prompted by a patient-family advocacy organization, oral HPV and HPV serological studies were simultaneously undertaken. Oral DNA samples from 201 individuals with FA, 303 unaffected family members, and 107 unrelated controls were tested for 37 HPV types. Serum samples from 115 individuals with FA and 55 unrelated controls were tested for antibodies against 9 HPV types. Oral HPV prevalence was higher for individuals with FA (20%) versus their parents (13%; p = 0.07), siblings (8%, p = 0.01), and unrelated controls (6%, p ≤ 0.001). A FA diagnosis increased HPV positivity 4.84-fold (95% CI: 1.96–11.93) in adjusted models compared to unrelated controls. Common risk factors associated with HPV in the general population did not predict oral positivity in FA, unlike unrelated controls. Seropositivity and anti-HPV titers did not significantly differ in FA versus unrelated controls regardless of HPV vaccination status. We conclude that individuals with FA are uniquely susceptible to oral HPV independent of conventional risk factors.

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