scholarly journals Strategies and cost-effectiveness evaluation of persistent albuminuria screening among high-risk population of chronic kidney disease

2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Huaiyu Wang ◽  
Li Yang ◽  
Fang Wang ◽  
Luxia Zhang
Keyword(s):  
Chronic Kidney Disease ◽  
Cost Effectiveness ◽  
High Risk ◽  
Kidney Disease ◽  
Effectiveness Evaluation ◽  
High Risk Population ◽  
Risk Population

scholarly journals THE PREDICTING FACTORS FOR CHRONIC KIDNEY DISEASE AMONG HIGH-RISK POPULATION IN LOWER NORTHERN, THAILAND

2020 ◽  
Vol 20 (2) ◽  
pp. 268-275
Author(s):  
Primprapha Konkaew ◽  
Pattama Suphunnakul
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Health Literacy ◽  
High Risk ◽  
Kidney Disease ◽  
Sampling Technique ◽  
High Risk Population ◽  
Cross Sectional ◽  
Risk Population ◽  
High Risk Populations

This research aimed to explore the factors predicting chronic kidney disease (CKD) in the high-risk population. A cross-sectional study had been conducted in the high-risk populations investigated with and without CKD were the participants. A total of 1,463 samples was enrolled by a multistage sampling technique was used to recruit participants from five provinces in the lower northern of Thailand. Data were collected using a questionnaire and analyzed with descriptive statistics, and binary logistic regression. The results were revealed the risk factors affecting CKD including aged, dyslipidemia, being ill of diabetes mellitus, being unable to control blood pressure, being unable to control blood sugar level, taking add more salty seasoning to the cooked food, cooking with sodium salt over the prescribed amount, using the non-steroidal anti-inflammatory drug, lack of exercise, herbal plants consumption as drugs that are toxic to the kidney, edema, foamy urine, and nocturia. All risk factors were able to co-predict the risk to CKD about 83.2% at the 0.05 level of significance. Therefore, to prevent early states with CKD in the high-risk populations, the focus should be on encouraging health literacy because health literary it has a positive relationship with health-promoting behaviors. The health care provider needs to concentrate on increasing health literacy for self– management with them.

scholarly journals Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Jiaojiao Jing ◽  
Arif B. Ekici ◽  
Thomas Sitter ◽  
Kai-Uwe Eckardt ◽  
Elke Schaeffner ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
High Risk ◽  
Kidney Disease ◽  
Serum Urate ◽  
High Risk Population ◽  
Risk Population

Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population

2015 ◽  
Vol 72 ◽  
pp. 162-166 ◽  
Author(s):  
Julia Raschenberger ◽  
Barbara Kollerits ◽  
Stephanie Titze ◽  
Anna Köttgen ◽  
Barbara Bärthlein ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
High Risk ◽  
Kidney Disease ◽  
High Risk Population ◽  
Risk Population

scholarly journals Prevalence of Chronic Kidney Disease among the High Risk Population in South-Western Ghana; A Cross Sectional Study

2015 ◽  
Vol 2 ◽  
pp. 76 ◽  
Author(s):  
Richard KD Ephraim ◽  
Sylvester Biekpe ◽  
Samuel A. Sakyi ◽  
Prince Adoba ◽  
Hope Agbodjakey ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
High Risk ◽  
Kidney Disease ◽  
Cross Sectional Study ◽  
High Risk Population ◽  
Sectional Study ◽  
Cross Sectional ◽  
Risk Population

scholarly journals P0255THE SHORT TERM MATERNAL OUTCOME OF PREGNANT CHRONIC KIDNEY DISEASE PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Christopher thiam seong Lim ◽  
Yun Jin Ong ◽  
Shao Wei Yong ◽  
Wee Ven Hing [email protected] ◽  
Mohammad Zulkarnain Bidin ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
High Risk ◽  
Kidney Disease ◽  
Blood Pressure Monitoring ◽  
Post Partum ◽  
Antibiotic Usage ◽  
High Risk Population ◽  
Multiple Pregnancies ◽  
Fetal Outcomes ◽  
Increased Risk

Abstract Background and Aims Pregnancy in chronic kidney disease (CKD) is associated with increased risk of adverse maternal outcomes and fetal outcomes. The risks are noticeable even in early stages of CKD. Despite the rising concern, there are few follow-up studies in this high-risk group. Method We followed up and analysed 538 pregnancies in 173 women with pre-existing of primary renal disease who were seen at a tertiary nephrology centre from January 2007 until December 2015. We sought to investigate the changes in laboratory and clinical parameters, maternal and fetal outcomes. Results Figure 1 showed the changes of parameters intra and post-partum period. Increase in weight (p=0.034, OR 1.135, 95% CI 1.01-1.276), antibiotics consumption (p=0.022, OR 0.088, 95% CI 0.011-0.0703), pregnancy-related hypertension (p=0.056, OR 0.161, 95% CI 0.025-1.05) and gromerulonephritis (p=0.049, OR 14.22, 95% CI 1.009- 200.52) were associated with worsening of proteinuria intra-pregnancy and post-pregnancy period. Age more than 30-year-old (p=0.024, OR 0.644, 95% CI 0.439-0.945), multiple pregnancies (p = 0.032, OR 14.4, 95% CI 1.25-165 , antibiotics usage (p=0.033, OR 27.59, 95% CI 1.302-585.169), diuretic usage (p=0.034, OR 0.003, 95% CI 1.26-0.646), pregnancy-related hypertension (p=0.06, OR 21.838, 95% CI 0.878-543.376) and proteinuria (> 1.5g/d) (p=0.025, OR 0.235 95% CI 0.067-0.717) and fetal complications such as fetal death (p=0.013, OR 3.608 95% CI 1.311-9.930) was associated with rapid renal function decline of 25-50% . Elevation of serum uric acid is associated with a higher risk of adverse fetal outcome (r=0.845 p=0.004). Conclusion Multiple pregnancies, antibiotic usage, pregnancy-related hypertension are strong predictors of rapid maternal rapid function decline. Pre-conception counselling, minimization of antibiotic usage and aggressive blood pressure monitoring and treatment should be part of the standard treatment for this high-risk population.

scholarly journals Cost-effectiveness of an insertable cardiac monitor in a high-risk population in the UK

Open Heart ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. e001037 ◽  
Author(s):  
Claudia I Rinciog ◽  
Laura M Sawyer ◽  
Alexander Diamantopoulos ◽  
Mitchell S V Elkind ◽  
Matthew Reynolds ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
High Risk ◽  
Oral Anticoagulants ◽  
Cost Effective ◽  
Sensitivity Analyses ◽  
High Risk Population ◽  
Risk Population ◽  
Life Years ◽  
The Uk ◽  
The Cost

ObjectiveTo evaluate the cost-effectiveness of insertable cardiac monitors (ICMs) compared with standard of care (SoC) for detecting atrial fibrillation (AF) in patients at high risk of stroke (CHADS2 >2), using a UK National Health Service (NHS) perspective.MethodsUsing patient characteristics and clinical data from the REVEAL AF trial, a Markov model assessed the cost-effectiveness of detecting AF with an ICM compared with SoC. Costs and benefits were extrapolated across modelled patient lifetime. Ischaemic and haemorrhagic strokes, intracranial and extracranial haemorrhages and minor bleeds were modelled. Diagnostic and device costs were included, plus costs of treating stroke and bleeding events and costs of oral anticoagulants (OACs). Costs and health outcomes, measured as quality-adjusted life years (QALYs), were discounted at 3.5% per annum. One-way deterministic and probabilistic sensitivity analyses (PSA) were undertaken.ResultsThe total per-patient cost for ICM was £13 360 versus £11 936 for SoC (namely, annual 24 hours Holter monitoring). ICMs generated a total of 6.50 QALYs versus 6.30 for SoC. The incremental cost-effectiveness ratio (ICER) was £7140/QALY gained, below the £20 000/QALY acceptability threshold. ICMs were cost-effective in 77.4% of PSA simulations. The number of ICMs needed to prevent one stroke was 21 and to cause a major bleed was 37. ICERs were sensitive to assumed proportions of patients initiating or discontinuing OAC after AF diagnosis, type of OAC used and how intense the traditional monitoring was assumed to be under SoC.ConclusionsThe use of ICMs to identify AF in a high-risk population is cost-effective for the UK NHS.

Risk of death without appropriate defibrillator shock in patients with advanced renal dysfunction

EP Europace ◽  
2019 ◽  
Vol 21 (3) ◽  
pp. 459-464 ◽  
Author(s):  
Ido Goldenberg ◽  
Tal Mor ◽  
Eyal Nof ◽  
Arwa Younis ◽  
Anat Berkovitch ◽  
...  
Keyword(s):  
High Risk ◽  
Kidney Disease ◽  
Shock Therapy ◽  
P Value ◽  
High Risk Population ◽  
Icd Implantation ◽  
Risk Population ◽  
Risk Of Death ◽  
Kaplan Meier ◽  
Icd Shock

Abstract Aims Heart failure patients with advanced chronic kidney disease (CKD) may experience an increased rate of non-arrhythmic mortality due to associated comorbidities. We aimed to evaluate the risk of mortality without appropriate implantable cardioverter-defibrillator (ICD) shocks in this high-risk population. Methods and results The study population comprised 3542 patients who received an ICD, were enrolled, and prospectively followed-up in the Israeli ICD registry. Study patients were categorized into two groups: those with advanced CKD [defined by a glomerular filtration rate of <30 mL/min/1.73 m2 or being on dialysis at time of implantation (n = 197)], and those without advanced CKD (n = 3344). The primary endpoint was the risk of death without receiving appropriate ICD shock. Kaplan–Meier survival analysis showed that at 5 years of follow-up the rates of death without prior ICD shock were significantly higher in the advanced kidney disease group (46%) compared with the non-advanced CKD group (19%; log-rank P-value <0.001). Consistently, multivariate analysis showed that the risk of death without receiving appropriate ICD shock therapy at 5 years was 2.5-fold (P < 0.001) higher among advanced CKD patients. In contrast, the rate of appropriate ICD shock therapy at 5 years among advanced CKD patients was only 9%, with a very high mortality rate (63%) within 3.5 years subsequent to shock therapy. Conclusion Nearly one-half of ICD with advanced CKD die within 5 years without receiving an appropriate ICD shock. These findings stress the importance of appropriate patient selection for primary ICD implantation in this high-risk population.

scholarly journals Cost-effectiveness of MRI compared to mammography for breast cancer screening in a high risk population

2009 ◽  
Vol 9 (1) ◽  
Author(s):  
Susan G Moore ◽  
Pareen J Shenoy ◽  
Laura Fanucchi ◽  
John W Tumeh ◽  
Christopher R Flowers
Keyword(s):  
Breast Cancer ◽  
Cost Effectiveness ◽  
Cancer Screening ◽  
High Risk ◽  
Breast Cancer Screening ◽  
High Risk Population ◽  
Risk Population
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