Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population

2015 ◽  
Vol 72 ◽  
pp. 162-166 ◽  
Author(s):  
Julia Raschenberger ◽  
Barbara Kollerits ◽  
Stephanie Titze ◽  
Anna Köttgen ◽  
Barbara Bärthlein ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
High Risk ◽  
Kidney Disease ◽  
High Risk Population ◽  
Risk Population

scholarly journals THE PREDICTING FACTORS FOR CHRONIC KIDNEY DISEASE AMONG HIGH-RISK POPULATION IN LOWER NORTHERN, THAILAND

2020 ◽  
Vol 20 (2) ◽  
pp. 268-275
Author(s):  
Primprapha Konkaew ◽  
Pattama Suphunnakul
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Health Literacy ◽  
High Risk ◽  
Kidney Disease ◽  
Sampling Technique ◽  
High Risk Population ◽  
Cross Sectional ◽  
Risk Population ◽  
High Risk Populations

This research aimed to explore the factors predicting chronic kidney disease (CKD) in the high-risk population. A cross-sectional study had been conducted in the high-risk populations investigated with and without CKD were the participants. A total of 1,463 samples was enrolled by a multistage sampling technique was used to recruit participants from five provinces in the lower northern of Thailand. Data were collected using a questionnaire and analyzed with descriptive statistics, and binary logistic regression. The results were revealed the risk factors affecting CKD including aged, dyslipidemia, being ill of diabetes mellitus, being unable to control blood pressure, being unable to control blood sugar level, taking add more salty seasoning to the cooked food, cooking with sodium salt over the prescribed amount, using the non-steroidal anti-inflammatory drug, lack of exercise, herbal plants consumption as drugs that are toxic to the kidney, edema, foamy urine, and nocturia. All risk factors were able to co-predict the risk to CKD about 83.2% at the 0.05 level of significance. Therefore, to prevent early states with CKD in the high-risk populations, the focus should be on encouraging health literacy because health literary it has a positive relationship with health-promoting behaviors. The health care provider needs to concentrate on increasing health literacy for self– management with them.

scholarly journals Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Jiaojiao Jing ◽  
Arif B. Ekici ◽  
Thomas Sitter ◽  
Kai-Uwe Eckardt ◽  
Elke Schaeffner ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
High Risk ◽  
Kidney Disease ◽  
Serum Urate ◽  
High Risk Population ◽  
Risk Population

scholarly journals Prevalence of Chronic Kidney Disease among the High Risk Population in South-Western Ghana; A Cross Sectional Study

2015 ◽  
Vol 2 ◽  
pp. 76 ◽  
Author(s):  
Richard KD Ephraim ◽  
Sylvester Biekpe ◽  
Samuel A. Sakyi ◽  
Prince Adoba ◽  
Hope Agbodjakey ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
High Risk ◽  
Kidney Disease ◽  
Cross Sectional Study ◽  
High Risk Population ◽  
Sectional Study ◽  
Cross Sectional ◽  
Risk Population

scholarly journals P0255THE SHORT TERM MATERNAL OUTCOME OF PREGNANT CHRONIC KIDNEY DISEASE PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Christopher thiam seong Lim ◽  
Yun Jin Ong ◽  
Shao Wei Yong ◽  
Wee Ven Hing [email protected] ◽  
Mohammad Zulkarnain Bidin ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
High Risk ◽  
Kidney Disease ◽  
Blood Pressure Monitoring ◽  
Post Partum ◽  
Antibiotic Usage ◽  
High Risk Population ◽  
Multiple Pregnancies ◽  
Fetal Outcomes ◽  
Increased Risk

Abstract Background and Aims Pregnancy in chronic kidney disease (CKD) is associated with increased risk of adverse maternal outcomes and fetal outcomes. The risks are noticeable even in early stages of CKD. Despite the rising concern, there are few follow-up studies in this high-risk group. Method We followed up and analysed 538 pregnancies in 173 women with pre-existing of primary renal disease who were seen at a tertiary nephrology centre from January 2007 until December 2015. We sought to investigate the changes in laboratory and clinical parameters, maternal and fetal outcomes. Results Figure 1 showed the changes of parameters intra and post-partum period. Increase in weight (p=0.034, OR 1.135, 95% CI 1.01-1.276), antibiotics consumption (p=0.022, OR 0.088, 95% CI 0.011-0.0703), pregnancy-related hypertension (p=0.056, OR 0.161, 95% CI 0.025-1.05) and gromerulonephritis (p=0.049, OR 14.22, 95% CI 1.009- 200.52) were associated with worsening of proteinuria intra-pregnancy and post-pregnancy period. Age more than 30-year-old (p=0.024, OR 0.644, 95% CI 0.439-0.945), multiple pregnancies (p = 0.032, OR 14.4, 95% CI 1.25-165 , antibiotics usage (p=0.033, OR 27.59, 95% CI 1.302-585.169), diuretic usage (p=0.034, OR 0.003, 95% CI 1.26-0.646), pregnancy-related hypertension (p=0.06, OR 21.838, 95% CI 0.878-543.376) and proteinuria (> 1.5g/d) (p=0.025, OR 0.235 95% CI 0.067-0.717) and fetal complications such as fetal death (p=0.013, OR 3.608 95% CI 1.311-9.930) was associated with rapid renal function decline of 25-50% . Elevation of serum uric acid is associated with a higher risk of adverse fetal outcome (r=0.845 p=0.004). Conclusion Multiple pregnancies, antibiotic usage, pregnancy-related hypertension are strong predictors of rapid maternal rapid function decline. Pre-conception counselling, minimization of antibiotic usage and aggressive blood pressure monitoring and treatment should be part of the standard treatment for this high-risk population.

Risk of death without appropriate defibrillator shock in patients with advanced renal dysfunction

EP Europace ◽  
2019 ◽  
Vol 21 (3) ◽  
pp. 459-464 ◽  
Author(s):  
Ido Goldenberg ◽  
Tal Mor ◽  
Eyal Nof ◽  
Arwa Younis ◽  
Anat Berkovitch ◽  
...  
Keyword(s):  
High Risk ◽  
Kidney Disease ◽  
Shock Therapy ◽  
P Value ◽  
High Risk Population ◽  
Icd Implantation ◽  
Risk Population ◽  
Risk Of Death ◽  
Kaplan Meier ◽  
Icd Shock

Abstract Aims Heart failure patients with advanced chronic kidney disease (CKD) may experience an increased rate of non-arrhythmic mortality due to associated comorbidities. We aimed to evaluate the risk of mortality without appropriate implantable cardioverter-defibrillator (ICD) shocks in this high-risk population. Methods and results The study population comprised 3542 patients who received an ICD, were enrolled, and prospectively followed-up in the Israeli ICD registry. Study patients were categorized into two groups: those with advanced CKD [defined by a glomerular filtration rate of <30 mL/min/1.73 m2 or being on dialysis at time of implantation (n = 197)], and those without advanced CKD (n = 3344). The primary endpoint was the risk of death without receiving appropriate ICD shock. Kaplan–Meier survival analysis showed that at 5 years of follow-up the rates of death without prior ICD shock were significantly higher in the advanced kidney disease group (46%) compared with the non-advanced CKD group (19%; log-rank P-value <0.001). Consistently, multivariate analysis showed that the risk of death without receiving appropriate ICD shock therapy at 5 years was 2.5-fold (P < 0.001) higher among advanced CKD patients. In contrast, the rate of appropriate ICD shock therapy at 5 years among advanced CKD patients was only 9%, with a very high mortality rate (63%) within 3.5 years subsequent to shock therapy. Conclusion Nearly one-half of ICD with advanced CKD die within 5 years without receiving an appropriate ICD shock. These findings stress the importance of appropriate patient selection for primary ICD implantation in this high-risk population.

scholarly journals Burden of chronic kidney disease in the general population and high-risk groups in South Asia: A systematic review and meta-analysis

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0258494
Author(s):  
Nipun Shrestha ◽  
Sanju Gautam ◽  
Shiva Raj Mishra ◽  
Salim S. Virani ◽  
Raja Ram Dhungana
Keyword(s):  
Public Health ◽  
Systematic Review ◽  
Chronic Kidney Disease ◽  
High Risk ◽  
Kidney Disease ◽  
General Population ◽  
South Asia ◽  
Meta Analysis ◽  
High Risk Population ◽  
Pooled Prevalence

Background Chronic kidney disease (CKD) is an emerging public health issue globally. The prevalence estimates on CKD in South Asia are however limited. This study aimed to examine the prevalence of CKD among the general and high-risk population in South Asia. Methods We conducted a systematic review and meta-analysis of population-level prevalence studies in South Asia (Afghanistan, Bangladesh, Bhutan, Maldives, Nepal, India, Pakistan, and Sri Lanka). Three databases namely PubMed, Scopus and Web of Science were systematically searched for published reports of kidney disease in South Asia up to 28 October 2020. A random-effect model for computing the pooled prevalence was used. Results Of the 8749 identified studies, a total of 24 studies were included in the review. The pooled prevalence of CKD among the general population was 14% (95% CI 11–18%), and 15% (95% CI 11–20%) among adult males and 13% (95% CI 10–17%) in adult females. The prevalence of CKD was 27% (95% CI 20–35%) in adults with hypertension, 31% (95% CI 22–41%) in adults with diabetes and 14% (95% CI 10–19%) in adults who were overweight/obese. We found substantial heterogeneity across the included studies in the pooled estimates for CKD prevalence in both general and high-risk populations. The prevalence of CKD of unknown origin in the endemic population was 8% (95% CI 3–16%). Conclusion Our study reaffirms the previous reports that CKD represents a serious public health challenge in South Asia, with the disease prevalent among 1 in 7 adults in South Asian countries.

The Health Check-Up Data-Analysis for Risk Assessment of Chronic Kidney Disease (CKD) in Taiwan

2021 ◽  
Author(s):  
Ming-Shu Chen ◽  
Mao-Jhen Jhou ◽  
Chi-Jie Lu ◽  
Chung-Chih Hung
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Risk Assessment ◽  
Chronic Kidney Disease ◽  
Risk Factor ◽  
High Risk ◽  
Kidney Disease ◽  
High Risk Population ◽  
Healthy Population ◽  
High Risk Factors

Early detection of chronic kidney disease (CKD) for high-risk population adults is very important. It has a common risk factor and causal relationship with chronic diseases such as diabetes, hypertension and cardiovascular disease etc. The results of this study provide that for early high-risk factors detection in CKD healthy population can be used by home care to recommend adjuvant treatment.

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