scholarly journals Socioeconomic disparities and infancy growth trajectory: a population-based and longitudinal study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zi-yu Shao ◽  
Peng Wang ◽  
Pei Li ◽  
Yu Sun ◽  
Pei-pei Li ◽  
...  

Abstract Background The association of low socioeconomic status (SES) with childhood and adolescent obesity has been reported. It is unknown whether low SES affects body mass index (BMI) growth trajectory in the first 12 mo of life. Moreover, accelerated growth as a compensatory mechanism for low birth weight (LBW) during infancy, is an important predictor of later obesity. The aim of the present study was to examine the association of low SES with infancy BMI growth rate and trajectory for LBW and normal birth weight (NBW) infants. Methods From September 2012 to October 2014, a total of 387 infants in this longitudinal study was subjected to repeated measures of weight and length from birth to 12 mo in Hefei. Generalized growth mixture modeling was used to classify the infancy BMI growth trajectories. Differences in infancy BMI z score (zBMI) and BMI growth rate between low SES and high SES were estimated based on linear regression after adjusting for several confounders including maternal age, pregnancy BMI, physical activity during pregnancy, paternal BMI as well as alcohol use, paternal smoking status, breastfeeding duration and delivery mode. Results Infancy BMI trajectories in this study were classified into three categories: rapid growth (class 1), normal growth (class 2) and slow growth (class 3). Low SES infants had the higher zBMI than high SES infants for LBW group at age 6 mo [zBMI difference with 95% CI at 6 mo: 0.28(0.03, 0.53); at 12 mo: 0.21(0.01, 0.43)]. Low SES infants had more rapid zBMI growth rate than those with high SES for low birth weight between 0 and 6 months. Controlling for the confounders, these associations remained robust. We found the lower SES in the rapid growth group. Conclusions These findings highlighted the impact of low SES on increasing BMI and accelerated growth during early infancy. Health care and relatively optimal family environment in the first 12 mo of life, especially for LBW infants, are benefit to shape the better infancy growth trajectory.

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Agnès Jamin ◽  
Bernard Sève ◽  
Jean-Noël Thibault ◽  
Nathalie Floc’h

Low-birth-weight neonates are routinely fed a high-protein formula to promote catch-up growth and antibiotics are usually associated to prevent infection. Yet the effects of such practices on tissue protein metabolism are unknown. Baby pigs were fed from age 2 to 7 or 28 d with high protein formula with or without amoxicillin supplementation, in parallel with normal protein formula, to determine tissue protein metabolism modifications. Feeding high protein formula increased growth rate between 2 and 28 days of age when antibiotic was administered early in the first week of life. This could be explained by the occurrence of diarrhea when piglets were fed the high protein formula alone. Higher growth rate was associated with higher feed conversion and reduced protein synthesis rate in the small intestine, muscle and carcass, whereas proteolytic enzyme activities measured in these tissues were unchanged. In conclusion, accelerated growth rate caused by high protein formula and antibiotics was not supported by increased protein synthesis in muscle and carcass.


1983 ◽  
Vol 103 (5) ◽  
pp. 793-796 ◽  
Author(s):  
Masao Sakaguchi ◽  
Shigeyoshi Suzuki ◽  
Kanji Nagashima ◽  
Satoshi Shimano ◽  
Satoshi Uchida ◽  
...  

2005 ◽  
Vol 38 (4) ◽  
pp. 523-535 ◽  
Author(s):  
CARLA JORGE MACHADO

The aim of this study is to analyse the impact of maternal age at first birth on low birth weight, preterm birth and low Apgar scores at one minute and at five minutes among live births delivered to primiparous Brazilian women in the city of São Paulo. Analyses were based on 73,820 birth records from the 1998 birth cohort. Logistic regression was used to assess the association between maternal age and each outcome variable, controlling for the following risk factors: delivery mode, plurality, sex, maternal education, number of prior losses, prenatal care, race, parity and community development. Maternal ages below 20 and above 30 years were significantly associated with the risks of low birth weight and preterm birth, but no association was found between maternal ages and Apgar score, with the exception that ages 15–19 reduced the odds of a low one-minute score. Even though this result seems to be inconsistent, low birth weight, preterm birth and low Apgar scores measure different dimensions of newborn well-being, and the association of each measure with maternal age is expected to diverge.


2020 ◽  
pp. 24-32
Author(s):  
R.V. Marushko ◽  
◽  
О.О. Dudina ◽  
T.L. Marushko ◽  
◽  
...  

Ukraine entered the 21st century with one of the worst vital signs in Europe and the burden of many socio-economic and demographic problems. Adverse quantitative and especially qualitative indicators of population reproduction have become stable. Therefore, the most important medical and social task and one of the main activities of the Ministry of Health of Ukraine is the formation and maintenance of public health. The defining stage in the formation of human health is the first year of life. Purpose — to study the state and trends of changes in the main indicators of the health of children in the first year of life for the period 2000–2019. Materials and methods. A retrospective analysis of the incidence of children in the first year of life, infant mortality, over the past 20 years in the context of individual pathological conditions is carried out. The information base of the study was the data of state and industry statistics for 2000–2019. Methods of a systematic approach, statistical data processing, epidemiological analysis of graphic images were used. Results. The study revealed that the unfavorable demographic situation in Ukraine is accompanied by an unsatisfactory state of the main predictors of a healthy start in the life of infants, the formation and maintenance of their health. Over the past two decades, there has been a high level with a negative trend of diseases of the reproductive system of women, a high frequency of the combination of pregnancy and extragenital diseases remains. There is a negative trend towards an increase in the generalized objective criterion of the health of the generation, which is born and the socio-economic well-being of the population — the frequency of premature, low birth weight, incl. With very low birth weight. Only thanks to the introduction of modern medical organizational technologies with proven efficiency in the activities of the maternal and child health service was it possible to achieve a decrease in the incidence of newborns from 280.8 per 1000 live births in 2000 up to 172.14 in 2019. At the same time, the increase in the incidence of newborns with diseases that have a direct impact on the development of chronic and disabling diseases at all stages of life is of concern — congenital pneumonia, neonatal sepsis, other disorders of the cerebral status of the newborn, neonatal jaundice. According to the assessment of the dynamics of the general morbidity of children in the first year of life, its level is still high, with a positive trend — 2018.8 per 1000 children who reached 1 year in 2000 and 1393.1 in 2019, the growth rate is -30.9% with a traditionally leading position in the level and structure of the incidence of respiratory diseases — 810.2 per 1000 children who have reached one year of life and 58.15%, certain conditions occurring in perinatal period — 126.7 ‰ and 9.06%, diseases of the skin and subcutaneous tissue — 63.9‰ and 4.59%, diseases of the blood and hematopoietic organs and certain disorders involving the immune mechanism — 63.0‰ and 4.52%. Conclusions. The positive dynamics of morbidity in children of the first year of life is confirmed by a decrease in infant mortality from its maximum level of 11.9 per 1000 live births in 2000 up to 7.0 in 2019, the growth rate is -41.2% due to all its components with a more intensive reduction in postneonatal mortality from 5.28‰ to 2.57‰, the growth rate is -51.3% against the background of an increase in the concentration of mortality in the neonatal period from 55.9% to 64.5%, respectively. No conflict of interest was declared by the authors. Key words: newborns, children of the first year of life, low birthweight newborns, morbidity, infant mortality.


2014 ◽  
Vol 103 (6) ◽  
pp. 651-658 ◽  
Author(s):  
Suvi Stolt ◽  
Jaakko Matomäki ◽  
Annika Lind ◽  
Helena Lapinleimu ◽  
Leena Haataja ◽  
...  

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