Lung function impairment and cardiometabolic risks among rural adults: implication for an aging society

Abstract Background Early detection and prevention of cardiometabolic risk factors in an increasingly aging society are a global public health concern. Maintaining adequate lung function is important for healthy aging. Few studies exist on lung function impairment and decline in primary healthcare settings, especially among rural adults with cardiometabolic risks. This study aimed to explore the prevalence of impaired lung function and its association with cardiometabolic risks among rural adults. Methods A community-based, cross-sectional study was conducted between March and December 2019 in western coastal Yunlin County, Taiwan. The lung function test was measured by spirometry, based on the American Thoracic Society recommendations. Three lung function parameters were obstructive lung impairment, restrictive lung impairment, and mixed lung impairment. Restrictive, obstructive, and mixed type lung function was categorized as impaired. Cardiometabolic risk factors and metabolic syndrome were based on the national standard and include five abnormal biomarkers, including abdominal obesity, blood pressure, fasting plasma glucose, triglycerides, and decreased high-density cholesterol levels. Results The median age of the 1653 (92.9%) participants with complete data was 66 years (interquartile range: 55 to 75 years). The prevalence of impaired lung function was 37%, including 31.7% restrictive, 2.5% obstructive, and 2.7% mixed type. Adults with impaired lung function (86% restrictive type) engaged more in smoking and betel nut chewing, ate fewer vegetables and fruit, and drank less water compared to the normal lung function group. After adjusting for potential confounding variables, multivariate logistic regression analysis showed that cardiometabolic risk factors were independently associated with restrictive lung impairment, while cigarette smoking (OR = 2.27, 95% CI = 1.14–4.53) and betel nut chewing (OR = 2.33, 95% CI = 1.09–5.01) were significantly associated with the obstructive type of lung impairment. Conclusions A high prevalence of restrictive lung impairment, cardiometabolic risks, and unhealthy lifestyles among rural adults were found in this study. For adults with cardiometabolic risks in rural areas, initiating lifestyle modifications with culture-tailored programs to improve lung function should be an important issue for clinicians and primary healthcare providers.

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Overweight, obesity and significant weight gain in adult patients with cystic fibrosis association with lung function and cardiometabolic risk factors

Clinical Nutrition ◽

10.1016/j.clnu.2019.12.029 ◽

2020 ◽

Vol 39 (9) ◽

pp. 2910-2916

Author(s):

Anne Bonhoure ◽

Valérie Boudreau ◽

Marina Litvin ◽

Johann Colomba ◽

Cindy Bergeron ◽

...

Keyword(s):

Risk Factors ◽

Cystic Fibrosis ◽

Weight Gain ◽

Lung Function ◽

Cardiometabolic Risk ◽

Cardiometabolic Risk Factors ◽

Adult Patients ◽

Significant Weight Gain

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Prevalence of and Factors Associated with Cardiometabolic Risks and Lung Function Impairment among Middle-Aged Women in Rural Taiwan

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17218067 ◽

2020 ◽

Vol 17 (21) ◽

pp. 8067

Author(s):

Ming-Shyan Lin ◽

Mei-Hua Yeh ◽

Mei-Yen Chen

Keyword(s):

Metabolic Syndrome ◽

Lung Function ◽

Community Health ◽

National Standard ◽

Middle Aged ◽

Factors Associated ◽

Increased Risk ◽

Function Impairment ◽

Cardiometabolic Risks ◽

Lung Function Impairment

Background: This study aims to explore the prevalence of and factors associated with cardiometabolic risks and lung function impairment among middle-aged women. Methods: A nurse-led community health development and cross-sectional study design was applied in Yunlin County, Taiwan. Lung function test was performed by a certified technician using a valid spirometer, during annual community health checkups conducted by a collaborating local hospital. Lung function impairment and cardiometabolic risks were measured and defined, based on the medical diagnosis and the national standard, by the hospital. Results: From a total of 439 middle-aged women, the prevalence of lung function impairment and metabolic syndrome were 26% and 47.2%, respectively. Many women adopted few health habits, e.g., only 30.5% engaged in regular exercise. A significant association between lung function impairment and four cardiometabolic risk factors (p < 0.05) was found. The multivariate logistic regression analysis showed that adopting few exercises (OR = 0.56, 95% CI 0.36–0.87) and lung function impairment (OR = 2.12, 95% CI 1.34–3.35) were independently associated with metabolic syndrome, after adjusting for confounding factors, such as age and education. Conclusions: The findings revealed that middle-aged women have a high prevalence of cardiometabolic risks and lung function impairment. Lung function impairment and physical inactivity were independently associated with an increased risk of having metabolic syndrome.

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Risk factors for lung function impairment among the general non-smoking Korean population

The International Journal of Tuberculosis and Lung Disease ◽

10.5588/ijtld.14.0929 ◽

2015 ◽

Vol 19 (9) ◽

pp. 1019-1026 ◽

Cited By ~ 7

Author(s):

J-P. Myong ◽

H-K. Yoon ◽

C. K. Rhee ◽

H-R. Kim ◽

J-W. Koo

Keyword(s):

Risk Factors ◽

Lung Function ◽

Korean Population ◽

Function Impairment ◽

Lung Function Impairment

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Increased monocyte to HDL cholesterol ratio in vitamin B12 deficiency: is it related to cardiometabolic risk?

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000668 ◽

2020 ◽

pp. 1-8

Author(s):

Sanem Kayhan ◽

Nazli Gulsoy Kirnap ◽

Mercan Tastemur

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Uric Acid ◽

Vitamin B12 ◽

Cardiometabolic Risk ◽

Vitamin B12 Deficiency ◽

Left Ventricular ◽

Cardiometabolic Risk Factors ◽

B12 Deficiency ◽

Deficiency Group

Abstract. Vitamin B12 deficiency may have indirect cardiovascular effects in addition to hematological and neuropsychiatric symptoms. It was shown that the monocyte count-to-high density lipoprotein cholesterol (HDL-C) ratio (MHR) is a novel cardiovascular marker. In this study, the aim was to evaluate whether MHR was high in patients with vitamin B12 deficiency and its relationship with cardiometabolic risk factors. The study included 128 patients diagnosed with vitamin B12 deficiency and 93 healthy controls. Patients with vitamin B12 deficiency had significantly higher systolic blood pressure (SBP), diastolic blood pressure (DBP), MHR, C-reactive protein (CRP) and uric acid levels compared with the controls (median 139 vs 115 mmHg, p < 0.001; 80 vs 70 mmHg, p < 0.001; 14.2 vs 9.5, p < 0.001; 10.2 vs 4 mg/dl p < 0.001; 6.68 vs 4.8 mg/dl, p < 0.001 respectively). The prevalence of left ventricular hypertrophy was higher in vitamin B12 deficiency group (43.8%) than the control group (8.6%) (p < 0.001). In vitamin B12 deficiency group, a positive correlation was detected between MHR and SBP, CRP and uric acid (p < 0.001 r:0.34, p < 0.001 r:0.30, p < 0.001 r:0.5, respectively) and a significant negative correlation was detected between MHR and T-CHOL, LDL, HDL and B12 (p < 0.001 r: −0.39, p < 0.001 r: −0.34, p < 0.001 r: −0.57, p < 0.04 r: −0.17, respectively). MHR was high in vitamin B12 deficiency group, and correlated with the cardiometabolic risk factors in this group, which were SBP, CRP, uric acid and HDL. In conclusion, MRH, which can be easily calculated in clinical practice, can be a useful marker to assess cardiovascular risk in patients with vitamin B12 deficiency.

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