scholarly journals Quantum algorithm for quicker clinical prognostic analysis: an application and experimental study using CT scan images of COVID-19 patients

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kinshuk Sengupta ◽  
Praveen Ranjan Srivastava

Abstract Background In medical diagnosis and clinical practice, diagnosing a disease early is crucial for accurate treatment, lessening the stress on the healthcare system. In medical imaging research, image processing techniques tend to be vital in analyzing and resolving diseases with a high degree of accuracy. This paper establishes a new image classification and segmentation method through simulation techniques, conducted over images of COVID-19 patients in India, introducing the use of Quantum Machine Learning (QML) in medical practice. Methods This study establishes a prototype model for classifying COVID-19, comparing it with non-COVID pneumonia signals in Computed tomography (CT) images. The simulation work evaluates the usage of quantum machine learning algorithms, while assessing the efficacy for deep learning models for image classification problems, and thereby establishes performance quality that is required for improved prediction rate when dealing with complex clinical image data exhibiting high biases. Results The study considers a novel algorithmic implementation leveraging quantum neural network (QNN). The proposed model outperformed the conventional deep learning models for specific classification task. The performance was evident because of the efficiency of quantum simulation and faster convergence property solving for an optimization problem for network training particularly for large-scale biased image classification task. The model run-time observed on quantum optimized hardware was 52 min, while on K80 GPU hardware it was 1 h 30 min for similar sample size. The simulation shows that QNN outperforms DNN, CNN, 2D CNN by more than 2.92% in gain in accuracy measure with an average recall of around 97.7%. Conclusion The results suggest that quantum neural networks outperform in COVID-19 traits’ classification task, comparing to deep learning w.r.t model efficacy and training time. However, a further study needs to be conducted to evaluate implementation scenarios by integrating the model within medical devices.

2021 ◽  
Vol 10 (2) ◽  
pp. 205846012199029
Author(s):  
Rani Ahmad

Background The scope and productivity of artificial intelligence applications in health science and medicine, particularly in medical imaging, are rapidly progressing, with relatively recent developments in big data and deep learning and increasingly powerful computer algorithms. Accordingly, there are a number of opportunities and challenges for the radiological community. Purpose To provide review on the challenges and barriers experienced in diagnostic radiology on the basis of the key clinical applications of machine learning techniques. Material and Methods Studies published in 2010–2019 were selected that report on the efficacy of machine learning models. A single contingency table was selected for each study to report the highest accuracy of radiology professionals and machine learning algorithms, and a meta-analysis of studies was conducted based on contingency tables. Results The specificity for all the deep learning models ranged from 39% to 100%, whereas sensitivity ranged from 85% to 100%. The pooled sensitivity and specificity were 89% and 85% for the deep learning algorithms for detecting abnormalities compared to 75% and 91% for radiology experts, respectively. The pooled specificity and sensitivity for comparison between radiology professionals and deep learning algorithms were 91% and 81% for deep learning models and 85% and 73% for radiology professionals (p < 0.000), respectively. The pooled sensitivity detection was 82% for health-care professionals and 83% for deep learning algorithms (p < 0.005). Conclusion Radiomic information extracted through machine learning programs form images that may not be discernible through visual examination, thus may improve the prognostic and diagnostic value of data sets.


Author(s):  
Amandeep Singh Bhatia ◽  
Renata Wong

Quantum computing is a new exciting field which can be exploited to great speed and innovation in machine learning and artificial intelligence. Quantum machine learning at crossroads explores the interaction between quantum computing and machine learning, supplementing each other to create models and also to accelerate existing machine learning models predicting better and accurate classifications. The main purpose is to explore methods, concepts, theories, and algorithms that focus and utilize quantum computing features such as superposition and entanglement to enhance the abilities of machine learning computations enormously faster. It is a natural goal to study the present and future quantum technologies with machine learning that can enhance the existing classical algorithms. The objective of this chapter is to facilitate the reader to grasp the key components involved in the field to be able to understand the essentialities of the subject and thus can compare computations of quantum computing with its counterpart classical machine learning algorithms.


2019 ◽  
Author(s):  
Ismael Araujo ◽  
Juan Gamboa ◽  
Adenilton Silva

To recognize patterns that are usually imperceptible by human beings has been one of the main advantages of using machine learning algorithms The use of Deep Learning techniques has been promising to the classification problems, especially the ones related to image classification. The classification of gases detected by an artificial nose is one other area where Deep Learning techniques can be used to seek classification improvements. Succeeding in a classification task can result in many advantages to quality control, as well as to preventing accidents. In this work, it is presented some Deep Learning models specifically created to the task of gas classification.


Sensors ◽  
2021 ◽  
Vol 21 (23) ◽  
pp. 7784
Author(s):  
Johan Wasselius ◽  
Eric Lyckegård Finn ◽  
Emma Persson ◽  
Petter Ericson ◽  
Christina Brogårdh ◽  
...  

Recent advances in stroke treatment have provided effective tools to successfully treat ischemic stroke, but still a majority of patients are not treated due to late arrival to hospital. With modern stroke treatment, earlier arrival would greatly improve the overall treatment results. This prospective study was performed to asses the capability of bilateral accelerometers worn in bracelets 24/7 to detect unilateral arm paralysis, a hallmark symptom of stroke, early enough to receive treatment. Classical machine learning algorithms as well as state-of-the-art deep neural networks were evaluated on detection times between 15 min and 120 min. Motion data were collected using triaxial accelerometer bracelets worn on both arms for 24 h. Eighty-four stroke patients with unilateral arm motor impairment and 101 healthy subjects participated in the study. Accelerometer data were divided into data windows of different lengths and analyzed using multiple machine learning algorithms. The results show that all algorithms performed well in separating the two groups early enough to be clinically relevant, based on wrist-worn accelerometers. The two evaluated deep learning models, fully convolutional network and InceptionTime, performed better than the classical machine learning models with an AUC score between 0.947–0.957 on 15 min data windows and up to 0.993–0.994 on 120 min data windows. Window lengths longer than 90 min only marginally improved performance. The difference in performance between the deep learning models and the classical models was statistically significant according to a non-parametric Friedman test followed by a post-hoc Nemenyi test. Introduction of wearable stroke detection devices may dramatically increase the portion of stroke patients eligible for revascularization and shorten the time to treatment. Since the treatment effect is highly time-dependent, early stroke detection may dramatically improve stroke outcomes.


2021 ◽  
Vol 11 (16) ◽  
pp. 7561
Author(s):  
Umair Iqbal ◽  
Johan Barthelemy ◽  
Wanqing Li ◽  
Pascal Perez

Blockage of culverts by transported debris materials is reported as the salient contributor in originating urban flash floods. Conventional hydraulic modeling approaches had no success in addressing the problem primarily because of the unavailability of peak floods hydraulic data and the highly non-linear behavior of debris at the culvert. This article explores a new dimension to investigate the issue by proposing the use of intelligent video analytics (IVA) algorithms for extracting blockage related information. The presented research aims to automate the process of manual visual blockage classification of culverts from a maintenance perspective by remotely applying deep learning models. The potential of using existing convolutional neural network (CNN) algorithms (i.e., DarkNet53, DenseNet121, InceptionResNetV2, InceptionV3, MobileNet, ResNet50, VGG16, EfficientNetB3, NASNet) is investigated over a dataset from three different sources (i.e., images of culvert openings and blockage (ICOB), visual hydrology-lab dataset (VHD), synthetic images of culverts (SIC)) to predict the blockage in a given image. Models were evaluated based on their performance on the test dataset (i.e., accuracy, loss, precision, recall, F1 score, Jaccard Index, region of convergence (ROC) curve), floating point operations per second (FLOPs) and response times to process a single test instance. Furthermore, the performance of deep learning models was benchmarked against conventional machine learning algorithms (i.e., SVM, RF, xgboost). In addition, the idea of classifying deep visual features extracted by CNN models (i.e., ResNet50, MobileNet) using conventional machine learning approaches was also implemented in this article. From the results, NASNet was reported most efficient in classifying the blockage images with the 5-fold accuracy of 85%; however, MobileNet was recommended for the hardware implementation because of its improved response time with 5-fold accuracy comparable to NASNet (i.e., 78%). Comparable performance to standard CNN models was achieved for the case where deep visual features were classified using conventional machine learning approaches. False negative (FN) instances, false positive (FP) instances and CNN layers activation suggested that background noise and oversimplified labelling criteria were two contributing factors in the degraded performance of existing CNN algorithms. A framework for partial automation of the visual blockage classification process was proposed, given that none of the existing models was able to achieve high enough accuracy to completely automate the manual process. In addition, a detection-classification pipeline with higher blockage classification accuracy (i.e., 94%) has been proposed as a potential future direction for practical implementation.


Complexity ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-15
Author(s):  
Zeynep Hilal Kilimci ◽  
Aykut Güven ◽  
Mitat Uysal ◽  
Selim Akyokus

Nowadays, smart devices as a part of daily life collect data about their users with the help of sensors placed on them. Sensor data are usually physical data but mobile applications collect more than physical data like device usage habits and personal interests. Collected data are usually classified as personal, but they contain valuable information about their users when it is analyzed and interpreted. One of the main purposes of personal data analysis is to make predictions about users. Collected data can be divided into two major categories: physical and behavioral data. Behavioral data are also named as neurophysical data. Physical and neurophysical parameters are collected as a part of this study. Physical data contains measurements of the users like heartbeats, sleep quality, energy, movement/mobility parameters. Neurophysical data contain keystroke patterns like typing speed and typing errors. Users’ emotional/mood statuses are also investigated by asking daily questions. Six questions are asked to the users daily in order to determine the mood of them. These questions are emotion-attached questions, and depending on the answers, users’ emotional states are graded. Our aim is to show that there is a connection between users’ physical/neurophysical parameters and mood/emotional conditions. To prove our hypothesis, we collect and measure physical and neurophysical parameters of 15 users for 1 year. The novelty of this work to the literature is the usage of both combinations of physical and neurophysical parameters. Another novelty is that the emotion classification task is performed by both conventional machine learning algorithms and deep learning models. For this purpose, Feedforward Neural Network (FFNN), Convolutional Neural Network (CNN), Recurrent Neural Network (RNN), and Long Short-Term Memory (LSTM) neural network are employed as deep learning methodologies. Multinomial Naïve Bayes (MNB), Support Vector Regression (SVR), Decision Tree (DT), Random Forest (RF), and Decision Integration Strategy (DIS) are evaluated as conventional machine learning algorithms. To the best of our knowledge, this is the very first attempt to analyze the neurophysical conditions of the users by evaluating deep learning models for mood analysis and enriching physical characteristics with neurophysical parameters. Experiment results demonstrate that the utilization of deep learning methodologies and the combination of both physical and neurophysical parameters enhances the classification success of the system to interpret the mood of the users. A wide range of comparative and extensive experiments shows that the proposed model exhibits noteworthy results compared to the state-of-art studies.


2020 ◽  
Author(s):  
Luna Zhang ◽  
Yang Zou ◽  
Ningning He ◽  
Yu Chen ◽  
Zhen Chen ◽  
...  

AbstractAs a novel type of post-translational modification, lysine 2-Hydroxyisobutyrylation (Khib) plays an important role in gene transcription and signal transduction. In order to understand its regulatory mechanism, the essential step is the recognition of Khib sites. Thousands of Khib sites have been experimentally verified across five different species. However, there are only a couple traditional machine-learning algorithms developed to predict Khib sites for limited species, lacking a general prediction algorithm. We constructed a deep-learning algorithm based on convolutional neural network with the one-hot encoding approach, dubbed CNNOH. It performs favorably to the traditional machine-learning models and other deep-learning models across different species, in terms of cross-validation and independent test. The area under the ROC curve (AUC) values for CNNOH ranged from 0.82 to 0.87 for different organisms, which is superior to the currently-available Khib predictors. Moreover, we developed the general model based on the integrated data from multiple species and it showed great universality and effectiveness with the AUC values in the range of 0.79 to 0.87. Accordingly, we constructed the on-line prediction tool dubbed DeepKhib for easily identifying Khib sites, which includes both species-specific and general models. DeepKhib is available at http://www.bioinfogo.org/DeepKhib.


2019 ◽  
pp. 016555151987764
Author(s):  
Ping Wang ◽  
Xiaodan Li ◽  
Renli Wu

Wikipedia is becoming increasingly critical in helping people obtain information and knowledge. Its leading advantage is that users can not only access information but also modify it. However, this presents a challenging issue: how can we measure the quality of a Wikipedia article? The existing approaches assess Wikipedia quality by statistical models or traditional machine learning algorithms. However, their performance is not satisfactory. Moreover, most existing models fail to extract complete information from articles, which degrades the model’s performance. In this article, we first survey related works and summarise a comprehensive feature framework. Then, state-of-the-art deep learning models are introduced and applied to assess Wikipedia quality. Finally, a comparison among deep learning models and traditional machine learning models is conducted to validate the effectiveness of the proposed model. The models are compared extensively in terms of their training and classification performance. Moreover, the importance of each feature and the importance of different feature sets are analysed separately.


2020 ◽  
Author(s):  
Manil Maskey ◽  
Rahul Ramachandran ◽  
Iksha Gurung ◽  
Muthukumaran Ramasubramanian ◽  
Aaron Kaulfus ◽  
...  

&lt;p&gt;Earth science researchers typically use event (an instance of an Earth science phenomenon) data for case study analysis. However, Earth science data search systems are currently limited to specifying a query parameter that includes the space and time of an event.&amp;#160; Such an approach results in researchers spending a considerable amount of time sorting through data to conduct research studies on events.&amp;#160; With the growing data volumes, it is imperative to investigate data-driven approaches to address this limitation in the data search system.&lt;/p&gt;&lt;p&gt;We describe several contributions towards alternative ways to accelerate event-based studies from large data archives.&amp;#160;&lt;/p&gt;&lt;p&gt;The first contribution is the use of a machine learning-based approach, an enabling data-driven technology, to detect Earth science events from image archives.&amp;#160; Specifically, the development of deep learning models to detect various Earth science phenomena is discussed.&amp;#160; Deep learning includes machine learning algorithms that consist of multiple layers, where each layer performs feature detection.&amp;#160;&amp;#160; We leverage recent advancements in deep learning techniques (mostly using convolutional neural networks (CNNs) that have produced state-of-the-art image classification results in many domains.&lt;/p&gt;&lt;p&gt;The second contribution is the development of an event database and a phenomena portal.&amp;#160; The phenomena portal utilizes the deep learning detected events cataloged in an event database.&amp;#160; The portal provides a user interface with several features including display of events of the day, spatio-temporal characteristics of events, and integration of user feedback.&lt;/p&gt;&lt;p&gt;The third contribution is the development of a cloud-native framework to automate and scale the deep learning models in a production environment.&lt;/p&gt;&lt;p&gt;The paper also discusses the challenges in developing an end-to-end Earth science machine learning project and possible approaches to address those challenges.&lt;/p&gt;


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