scholarly journals Comparing the inflammatory profiles for incidence of diabetes mellitus and cardiovascular diseases: a prospective study exploring the ‘common soil’ hypothesis

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Xue Bao ◽  
Yan Borné ◽  
Linda Johnson ◽  
Iram Faqir Muhammad ◽  
Margaretha Persson ◽  
...  

2017 ◽  
Author(s):  
Rosa Marquez-Pardo ◽  
Isabel Torres-Barea ◽  
Mgloria Baena-Nieto ◽  
Concepcion Cruzado-Begines ◽  
Manuel Cayon-Blanco ◽  
...  


2021 ◽  
Author(s):  
Saba S. Memon ◽  
Anurag Lila ◽  
Rohit Barnabas ◽  
Manjunath Goroshi ◽  
Vijaya Sarathi ◽  
...  


2021 ◽  
pp. 130-133
Author(s):  
Seema Patel ◽  
A. Z. Nitnaware ◽  
R. T. Pawar ◽  
Ashish Keche ◽  
Tanvi Rekhade

Recently an increase in the incidence of mucormycosis is noticed in COVID-19 cases. The main aim of this study is to present our experience of rhino-orbito-cerebral mucormycosis in COVID-19 patients and thereby aid its early diagnosis and treatment. This is a prospective study of 12 cases diagnosed as Rhino-orbito-cerebral mucormycosis . Presentation of mucormycosis in COVID-19, their temporal association and outcome of treatment was studied. Pre-existing comorbidities were seen in 91.67% patients, Diabetes Mellitus (83.33%). Previous history of COVID-19 infection and treatment for the same in 41.67% cases, concomitant infection in 16.67% and asymptomatic undiagnosed covid (antibodies positive) was detected in 41.67%. All patients showed improvement in general and nasal condition (100%). Early diagnosis is must.



2019 ◽  
Vol 7 (2) ◽  
pp. 36
Author(s):  
Aadil Beigh ◽  
Sandeep Patil ◽  
Satish Balan ◽  
Praveen Murlidharan ◽  
Sagar Jethwa ◽  
...  


2014 ◽  
Vol 13 (4) ◽  
pp. 403-410 ◽  
Author(s):  
Diego García-Compeán ◽  
Joel O. Jáquez-Quintana ◽  
Fernando J. Lavalle-González ◽  
José A. González-González ◽  
Héctor J. Maldonado-Garza ◽  
...  




Author(s):  
Anna C van der Burgh ◽  
Arthur Moes ◽  
Brenda C T Kieboom ◽  
Teun van Gelder ◽  
Robert Zietse ◽  
...  

Abstract Background Retrospective studies suggest that tacrolimus-induced hypomagnesaemia is a risk factor for post-transplant diabetes mellitus (PTDM), but prospective studies are lacking. Methods This was a prospective study with measurements of serum magnesium and tacrolimus at pre-specified time points in the first year after living donor kidney transplantation (KT). The role of single nucleotide polymorphisms (SNPs) in hepatocyte nuclear factor 1β (HNF1β) was also explored because HNF1β regulates insulin secretion and renal magnesium handling. Repeated measurement and regression analyses were used to analyse associations with PTDM. Results In our cohort, 29 out of 167 kidney transplant recipients developed PTDM after 1 year (17%). Higher tacrolimus concentrations were significantly associated with lower serum magnesium and increased risk of hypomagnesaemia. Patients who developed PTDM had a significantly lower serum magnesium trajectory than patients who did not develop PTDM. In multivariate analysis, lower serum magnesium, age and body mass index were independent risk factors for PTDM. In recipients, the HNF1β SNP rs752010 G > A significantly increased the risk of PTDM [odds ratio (OR) = 2.56, 95% confidence interval (CI) 1.05–6.23] but not of hypomagnesaemia. This association lost significance after correction for age and sex (OR = 2.24, 95% CI 0.90–5.57). No association between HNF1β SNPs and PTDM was found in corresponding donors. Conclusions A lower serum magnesium in the first year after KT is an independent risk factor for PTDM. The HNF1β SNP rs752010 G > A may add to this risk through an effect on insulin secretion rather than hypomagnesaemia, but its role requires further confirmation.





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