scholarly journals Assessment of the usefulness of anti-Wb123 antibody for post-elimination surveillance of lymphatic filariasis

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Ameyo Monique Dorkenoo ◽  
Adjaho Koba ◽  
Wemboo A. Halatoko ◽  
Minongblon Teko ◽  
Komlan Kossi ◽  
...  
Keyword(s):  
Lymphatic Filariasis ◽  
Specific Antigen ◽  
Public Health Problem ◽  
Wuchereria Bancrofti ◽  
World Health ◽  
School Age Children ◽  
Enzyme Linked Immunosorbent Assay ◽  
Cross Sectional ◽  
Apparent Lack ◽  
Endemic District

Abstract Background The World Health Organization has targeted lymphatic filariasis (LF) for elimination as a public health problem and recommends, among other measures, post-elimination surveillance of LF. The identification of sensitive and specific surveillance tools is therefore a research priority. The Wuchereria bancrofti-specific antigen Wb123-based enzyme-linked immunosorbent assay (Wb123 ELISA) detects antibodies to the recombinant Wb123 antigen of W. bancrofti and may be useful as a surveillance tool for LF. Six years after stopping mass drug administration to eliminate LF and recording successful results on two post-treatment transmission assessment surveys, a study was conducted in Togo aimed at helping to identify the role of the Wb123 ELISA in post-validation surveillance of LF. Methods This was a cross-sectional study in eight previously LF-endemic districts and one non-endemic district in Togo. In each sub-district of these nine districts, two schools were selected and 15 children aged 6 to 9 years old at each school provided finger-stick blood for testing for antibodies to Wb123 using the Filaria Detect™ IgG4 ELISA kit® (InBios, International, Inc., Seattle, WA, USA). Results A total of 2654 children aged 6 to 9 years old were tested in 134 schools in the nine districts. Overall, 4.7% (126/2654) children tested positive for antibodies to the Wb123 antigen of W. bancrofti. The prevalence of Wb123 antibodies varied across the eight previously endemic LF districts, from 1.56 to 6.62%. The highest prevalence, 6.99%, was found in the non-endemic district, but this was not significantly different from the average of all the LF districts (4.49%, P = 0.062). Conclusions The Wb123 ELISA was positive in 4.7% of Togolese school-age children who were almost certainly unexposed to LF. This apparent lack of specificity in the Togo context makes it difficult to establish a seroprevalence threshold that could serve to signal LF resurgence in the country, precluding the use of this test for post-validation surveillance in Togo. There remains a need to develop a useful and reliable test for post-elimination surveillance for LF in humans.

scholarly journals Praziquantel treatment coverage among school age children against Schistosomiasis and associated factors in Ethiopia: a cross-sectional survey, 2019

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yilma Chisha ◽  
Zerihun Zerdo ◽  
Mekuria Asnakew ◽  
Chuchu Churko ◽  
Manaye Yihune ◽  
...  
Keyword(s):  
Treatment Approach ◽  
Public Health Problem ◽  
Integrated Treatment ◽  
School Enrollment ◽  
World Health ◽  
School Age Children ◽  
School Age ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Treatment Coverage

Abstract Background World Health Organization estimated that 779 million people are at risk of getting schistosomiasis (SCH) and 240 million people were infected worldwide. SCH due to Schistosoma mansoni (S. mansoni) is a wide public health problem in Ethiopia. The aim of the survey was to quantify national and district disaggregated treatment coverage status for SCH and compare validated coverage with the one reported. Methods Community based cross-sectional survey was conducted in April 2019 among households with school age children (SAC) 5–14 years in seven purposively selected districts of the country. Segments to be surveyed were randomly selected and households to be interviewed from each segment were determined using systematic sampling technique. A total of 3378 households visited and 5679 SAC (5–14 years) were interviewed. Results Overall reported treatment coverage of Praziquantel (PZQ) against SCH was 4286 (75.5%). Males were 27% more likely to swallow the drug (AOR = 1.27; 95% CI: 1.09, 1.47) than females. SAC with age 10–14 years were 45% more likely to swallow the drug compared with their counter parts (5–9 years), (AOR =1.45; 95% CI: 1.25, 1.69). There is statistically significant association between PZQ swallowing status with school enrollment. (AOR = 20.90, 95% CI: 17.41, 25.08). Swallowing status of PZQ against SCH significantly higher for SAC treated in districts applied integrated treatment approach (87.5%) compared with SAC treated in vertical treatment approach (72.5%); P-value < 0.001. SACs were asked for reasons for not taking the drug and the main reported reason for not swallowing PZQ in the present study was none attending of the school. Conclusions Over all treatment coverage of PZQ against SCH in the present study was 75.5%. Although it is in accordance with WHO recommendation for Ethiopia, national programmatic improvements are necessary to achieve higher coverage in the future. To increase treatment coverage for PZQ against SCH in Ethiopia, school based training should target all schools. Moreover, mobilization, sensitization and implementation of the community wide treatment need to be improved.

scholarly journals Praziquantel treatment coverage among school age children against schistosomiasis associated factors and in Ethiopia: a cross-sectional survey, 2019

2020 ◽  
Author(s):  
Yilma Chisha ◽  
Zerihun Zerdo ◽  
Mekuria Asnakew ◽  
Chuchu Churko ◽  
Manaye Yihune ◽  
...  
Keyword(s):  
Public Health Problem ◽  
Integrated Treatment ◽  
School Enrollment ◽  
World Health ◽  
School Age Children ◽  
Systematic Sampling ◽  
School Age ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Treatment Coverage

Abstract Background: World Health Organization estimated that 779 million people are at risk of getting schistosomiasis and 240 million people were infected worldwide. Schistosomiasis due to S. mansoni is a wide public health problem in Ethiopia. The aim of the survey was to quantify national and district disaggregated treatment coverage status for schistosomiasis and compare validated coverage with the one reported. Methods: Community based cross-sectional survey was conducted in April 2019 among households with school age children (5-14 years) in seven purposively selected districts of the country. Segments (villages within the selected kebele) to be surveyed were randomly selected and households to be interviewed from each segment were determined using systematic sampling technique. A total of 3,378 households visited and 5,679 school age children (5-14 years)) were interviewed.Results: Overall reported treatment coverage of schistosomiasis was 4286 (75.5%). Male SAC were 27% more likely to consume the drug (AOR= 1.27; 95% CI: 1.09, 1.47) than females. SAC with 10-14 years swallowed the drug 45% better than 5-9 years (AOR =1.45; 95%CI: 1.25, 1.69). Statistically significant association was observed between Praziquantel swallowing with school enrollment and heard about mass drug administration. Swallowing status of Praziquantel against schistosomiasis significantly higher for SAC treated in districts applied integrated treatment approach (87.5%) compared with SAC treated in vertical approach (72.5%). Reasons for not taking the drug were asked and the main reported reason for not swallowing Praziquantel in the present study was none attending of the school.Conclusion and recommendation Over all treatment coverage of Praziquantel against schistosomiasis in the present study was 75.5%. Although it is in accordance with WHO recommendation for Ethiopia, national programmatic improvements are necessary to achieve higher coverage. To increase treatment coverage of Praziquantel in Ethiopia, school based training should target all schools and mobilization, sensitization and implementation of the community wide treatment need to be improved.

scholarly journals Filariasis Limfatik di Kelurahan Pabean Kota Pekalongan

2008 ◽  
Vol 3 (2) ◽  
pp. 51
Author(s):  
Tri Ramadhani
Keyword(s):  
Public Health ◽  
Chronic Disease ◽  
Lymphatic Filariasis ◽  
Public Health Problem ◽  
Wuchereria Bancrofti ◽  
Disease Rate ◽  
Cross Sectional ◽  
Community Behavior ◽  
Clinical Survey ◽  
Cross Sectional Design

Filariasis limfatik masih merupakan masalah kesehatan masyarakat di Indonesia, khususnya di Kota Pekalongan. Hal ini ditandai dengan semakin meningkatnya angka mikrofilaria dan perluasan daerah dengan kasus filariasis limfatik.Tujuan penelitian adalah untuk mengetahui situasi filariasis limfatik diKelurahan Pabean Kota Pekalongan. Penelitian ini meliputi penduduk dan agent, dalam periode sekitar enam bulan (Juli-Desember 2007) dengan disain studi cross sectional. Pada penelitian ini dilakukan pemeriksaan klinis, survei darah jari dan identifikasi parasit penyebab filariasis limfatik. Hasil penelitian menunjukkan angka mikrofilaria (3,4) angka kesakitan akut filaria (0,4 %) yang tinggi, tetapi angka kesakitan kronis filaria rendah (0,00 %). Parasit penyebabfilariasis di Kelurahan Pabean adalah jenis Wuchereria bancrofti dengan kepadatan rerata mikrofilaria yang tinggi. Pengendalian filariasis limfatik di Kelurahan Pabean perlu dilakukan dengan pengobatan massal dan perubahan perilaku masyarakat.Kata kunci : Filariasis limfatik, kelurahan pabean, mikrofilaria.AbstractLymphatic filariasis is still being a public health problem in Indonesia, especially in Pekalongan district. This problem marked by the increasing rate of microfilaria and areas with lymphatic filariasis. The aim of this study is to know the epidemiologic situation of lymphatic filariasis in Pabean village Pekalongan district. The research was a cross-sectional design and covered host and agent within the period of July-Desember 2007. Data were collected through clinical survey of acute and chronic filariasis symptoms, blood survey and identification of lymphatic filariasis parasite. The result showed that microfilaremia rate was 3,4%, acute disease rate (ADR) 0,4 % and the chronic disease rate (CDR) 0,00 %. The average of microfilaria density in 1 ml blood was 465,63. Based onmicrofilaremia identification in the blood, the lymphatic filariasis agent in Pabean village is Wuchereria bancrofti type. Lymphatic filariasis control in Pabean village need to focused on Mass Drug Administration (MDA) and community behavior for healthy life.Key words : Lymphatic filariasis, pabean village, microfilaria.

scholarly journals PENGARUH DUKUNGAN KELUARGA TERHADAP SIKAP KEPALA KELUARGA TENTANG PENYAKIT FILARIASIS DI RW 02 KAMPUNG DUSUN PUSAKA KECAMATAN PUSAKO KABUPATEN SIAK

2018 ◽  
Vol 7 (2) ◽  
pp. 9-14
Author(s):  
Rifa Yanti ◽  
Fitra Mayenti
Keyword(s):  
Public Health ◽  
World Health Organization ◽  
Lymphatic Filariasis ◽  
Health Problem ◽  
Public Health Problem ◽  
World Health ◽  
Cross Sectional ◽  
Global Goal ◽  
Health Organization

Latar Belakang : Filariasis salah satu jenis penyakit yang mendapat perhatian khusus di dunia kesehatan, lebih dari 1(satu) miliar penduduk dunia memiliki risiko menderita filariasis dan lebih dari 120 juta orang dari 80 negara telah terinfeksi filariasis. WHO (World Health Organization) mencanangkan kesepakatan global untuk memberantas penyakit filariasis dengan The Global Goal of Elimination of Lymphatic Filariasis as Public Health Problem by the Year 2020       (WHO, 2010). Pada tahun 2003, penyakit filariasis di Indonesia dilaporkan sebanyak 6.571 kasus. Pada tahun 2007 dijumpai 11.473 kasus dan pada tahun 2008 terdapat 11.699 kasus kemudian meningkat menjadi 11.914 kasus pada tahun 2009. Hampir ribuan desa di 26 provinsi di Indonesia dinyatakan endemis. (Kemenkes  RI,  2010). Tujuan penelitian ini mengetahui pengaruh dukungan keluarga dengan sikap kepala keluarga tentang penyakit filariasis di RW 02 Kampung Dusun Pusaka Kecamatan Pusako Kabupaten Siak. Metode penelitian kuantitatif observational dengan pendekatan cross sectional. Pengumpulan data dilakukan dengan cara menyebarkan angket dan dianalisis secara univariat dan bivariat. Hasil penelitian didapatkan dari 116 repsonden, 62.1% dukungan keluarga baik dan 37.9% dukungan keluarga kurang baik, dan sikap kepala keluarga 60,3% positif dan 39,7%  sikap responden negatif. Hasil uji statistik didapatkan ada pengaruh yang signifikan antara dukungan keluarga terhadap sikap kepala keluarga tentang penyakit filariasis (p.Value = 0,00). Diharapkan kepada petugas kesehatan agar lebih aktif menggiatkan serta memberikan penyuluhan tentang penyakit filariasis khususnya di RW 02.

scholarly journals Low Seroprevalence of Measles-Specific IgG in Children of Three Ethnic Groups from Mexico: Influence of Age, Sex, Malnutrition and Family Size

Vaccines ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 295
Author(s):  
Miguel A. Sánchez-Alemán ◽  
Ilse A. Gutiérrez-Pérez ◽  
Nayeli Díaz-Salgado ◽  
Oscar Zaragoza-García ◽  
María Olamendi-Portugal ◽  
...  
Keyword(s):  
Ethnic Groups ◽  
Family Size ◽  
Public Health Problem ◽  
Vulnerable Groups ◽  
School Age Children ◽  
Enzyme Linked Immunosorbent Assay ◽  
Igg Antibodies ◽  
Cross Sectional ◽  
Southern Mexico ◽  
Antibody Levels

Background: The reemergence of measles represents a public health problem. The aim of the study was to determine the seroprevalence of IgG antibodies against measles in children of three ethnic groups in southern Mexico and the nutritional status and demographic risk factors associated. Methods: A cross-sectional study in 416 school-age children, 207 belonging to the Tlapaneco ethnic group, 101 to the Mixteco group and 108 were considered Mestizo. Sociodemographic data were collected, an anthropometric evaluation of the children was performed and a fasting blood sample was obtained from each child for the measurement of measles IgG antibodies by Enzyme-Linked Immunosorbent Assay (ELISA). Results: From the total sample, 59% of the children were seropositive for IgG antibodies against measles; in contrast, 41% lacked IgG antibodies. Measles antibody seropositivity was higher in girls (64%). 90.5% of 6-year-old children had higher antibodies seroprevalence, compared to the children between 10 and 13 years old (45.5%). In the three ethnic groups, age was negatively correlated with the index standard ratio (ISR) of measles antibody levels and the families with ≥8 members showed less seropositivity. According to the antibodies levels, most of the positive cases remained around 1 Standard Deviation (SD) of the ISR values and no underweight children had antibody levels above 2 SD. Conclusions: The Anti-Measles serological coverage is low in children of three ethnic groups from Southern Mexico and the age, sex, malnutrition and family size are associated factors. Therefore, it is important to strengthen immunization campaigns, principally in vulnerable groups.

scholarly journals A study to assess mass drug administration of DEC for filaria control in district Satna, Madhya Pradesh: a mid term assessment

2018 ◽  
Vol 5 (3) ◽  
pp. 1201
Author(s):  
Vivek Sharma ◽  
Vikrant Kabirpanthi
Keyword(s):  
Lymphatic Filariasis ◽  
Drug Administration ◽  
Mass Drug Administration ◽  
Public Health Problem ◽  
Wuchereria Bancrofti ◽  
Cross Sectional Study ◽  
Urban Site ◽  
Major Public Health Problem ◽  
Sectional Study ◽  
Cross Sectional

Background: Lymphatic filariasis is a major public health problem which is caused by Wuchereria Bancrofti and Brugia Malai. The disease is endemic in 250 districts in 20 states and UTs. In India national health policy 2002 envisages elimination of lymphatic filariasis by 2015. Important strategy for elimination of lymphatic filariasis is through annual mass drug administration of single dose of DEC for 5 year or more to the eligible population. Present cross sectional study was carried out to assess drug compliance after mass drug administration of DEC and the factors responsible for poor compliance among the population of Satna district of MP.Methods: The present study was a cross-sectional study which was carried out in filarial endemic Satna district. In this district 120 houses from 3 CHC & one urban ward was randomly selected. 30 households each from 3 rural and one urban site were interviewed related to MDA for DEC.Results: Coverage of tablet distribution in Satna was 90.9%. Consumption of drug among the people who received the drug was 87.97%, while the total effective consumption was 79.9%. Drug distributors ensured consumption of drug in only 16.9%.Conclusions: Focus of MDA is primarily to mere distribution of drug. There is need to give emphasis on consumption of drug, health education, common side effects and its management in order to increase effective coverage rate. 

scholarly journals Praziquantel treatment coverage among school age children against  Schistosomiasis and associated factors in Ethiopia: a cross-sectional survey, 2019

2020 ◽  
Author(s):  
Yilma Chisha Dea ◽  
Zerihun Zerdo ◽  
Mekuria Asnakew ◽  
Chuchu Churko ◽  
Manaye Yihune ◽  
...  
Keyword(s):  
Treatment Approach ◽  
Public Health Problem ◽  
Integrated Treatment ◽  
School Enrollment ◽  
World Health ◽  
School Age Children ◽  
School Age ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Treatment Coverage

Abstract Background: World Health Organization estimated that 779 million people are at risk of getting schistosomiasis (SCH) and 240 million people were infected worldwide. SCH due to schistosoma mansoni (S. mansoni) is a wide public health problem in Ethiopia. The aim of the survey was to quantify national and district disaggregated treatment coverage status for SCH and compare validated coverage with the one reported. Methods: Community based cross-sectional survey was conducted in April 2019 among households with school age children (SAC) 5-14 years in seven purposively selected districts of the country. Segments to be surveyed were randomly selected and households to be interviewed from each segment were determined using systematic sampling technique. A total of 3,378 households visited and 5,679 SAC (5-14 years) were interviewed.Results: Overall reported treatment coverage of Praziquantel (PZQ) against SCH was 4286 (75.5%). Males were 27% more likely to swallow the drug (AOR= 1.27; 95% CI: 1.09, 1.47) than females. SAC with age 10-14 years were 45% more likely to swallow the drug compared with their counter parts (5-9 years), (AOR =1.45; 95% CI: 1.25, 1.69). There is statistically significant association between PZQ swallowing status with school enrollment. (AOR= 20.90, 95% CI: 17.41, 25.08). Swallowing status of PZQ against SCH significantly higher for SAC treated in districts applied integrated treatment approach (87.5%) compared with SAC treated in vertical treatment approach (72.5%); P-value <0.001. SACs were asked for reasons for not taking the drug and the main reported reason for not swallowing PZQ in the present study was none attending of the school.Conclusions Over all treatment coverage of PZQ against SCH in the present study was 75.5%. Although it is in accordance with WHO recommendation for Ethiopia, national programmatic improvements are necessary to achieve higher coverage in the future. To increase treatment coverage for PZQ against SCH in Ethiopia, school based training should target all schools. Moreover, mobilization, sensitization and implementation of the community wide treatment need to be improved.

scholarly journals Praziquantel treatment coverage among school age children against   Schistosomiasis and associated factors in Ethiopia: a cross-sectional survey, 2019

2020 ◽  
Author(s):  
Yilma Chisha ◽  
Zerihun Zerdo ◽  
Mekuria Asnakew ◽  
Chuchu Churko ◽  
Manaye Yihune ◽  
...  
Keyword(s):  
Treatment Approach ◽  
Public Health Problem ◽  
Integrated Treatment ◽  
School Enrollment ◽  
World Health ◽  
School Age Children ◽  
School Age ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Treatment Coverage

Abstract Background: World Health Organization estimated that 779 million people are at risk of getting schistosomiasis (SCH) and 240 million people were infected worldwide. SCH due to schistosoma mansoni (S. mansoni) is a wide public health problem in Ethiopia. The aim of the survey was to quantify national and district disaggregated treatment coverage status for SCH and compare validated coverage with the one reported. Methods: Community based cross-sectional survey was conducted in April 2019 among households with school age children (SAC) 5-14 years in seven purposively selected districts of the country. Segments to be surveyed were randomly selected and households to be interviewed from each segment were determined using systematic sampling technique. A total of 3,378 households visited and 5,679 SAC (5-14 years) were interviewed.Results: Overall reported treatment coverage of PZQ against SCH was 4286 (75.5%). Males were 27% more likely to swallow the drug (AOR= 1.27; 95% CI: 1.09, 1.47) than females. SAC with age 10-14 years were 45% more likely to swallow the drug compared with their counter parts (5-9 years), (AOR =1.45; 95% CI: 1.25, 1.69). Statistically significant association was observed between PZQ swallowing with school enrollment and heard about mass drug administration. Swallowing status of PZQ against SCH significantly higher for SAC treated in districts applied integrated treatment approach (87.5%) compared with SAC treated in vertical treatment approach (72.5%). SACs were asked for reasons for not taking the drug and the main reported reason for not swallowing PZQ in the present study was none attending of the school.Conclusion and recommendation : Over all treatment coverage of PZQ against SCH in the present study was 75.5%. Although it is in accordance with WHO recommendation for Ethiopia, national programmatic improvements are necessary to achieve higher coverage in the future. To increase treatment coverage for PZQ against SCH in Ethiopia, school based training should target all schools. Moreover, mobilization, sensitization and implementation of the community wide treatment need to be improved.

scholarly journals Monitoring migrant groups as a post-validation surveillance approach to contain the potential reemergence of lymphatic filariasis in Togo

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Monique Ameyo Dorkenoo ◽  
Martin Kouame Tchankoni ◽  
Degninou Yehadji ◽  
Kossi Yakpa ◽  
Mawèké Tchalim ◽  
...  
Keyword(s):  
Lymphatic Filariasis ◽  
Significant Risk ◽  
Public Health Problem ◽  
Test Strip ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
Positive Case ◽  
Cross Sectional ◽  
Case Investigation ◽  
Migrant Groups

Abstract Background In March 2017, Togo was declared the first country in sub-Saharan Africa to eliminate lymphatic filariasis as a public health problem, but post-validation surveillance has been lacking. In some areas of the country, migrant groups from neighboring countries that are still endemic for LF pose a risk of reintroduction of LF to Togo. The objective of this study was to identify the risk posed by migrant groups by measuring their prevalence of LF infection and investigating any positive case using Togo’s case investigation algorithm to prevent resurgence of LF and sustain Togo’s elimination success. Method A cross-sectional study was conducted in 2018 in the northernmost region of the country. Three migrant populations were identified: (i) nomadic Peuhls, (ii) Togolese members of local communities who migrate annually to neighboring countries for seasonal labor, and (iii) refugees from Ghana who came to Togo because of a communal conflict in Ghana. A questionnaire was designed to collect data on demographics and history of LF and MDA; all participants were tested for circulating filariasis antigen (CFA) using the filariasis test strip (FTS). Any CFA-positive case was confirmed with nocturnal microfilaremia. Results Refugees, seasonal economic migrants and nomadic Peuhls represented 42.1%, 31.4% and 26.5% of the study participants, respectively. The overall prevalence of CFA was 4.2% (58/1391) with the highest prevalence in the nomadic Peuhl group (11.9%), but only one of them (0.07%) was confirmed positive with nocturnal microfilaremia. Using the case investigation algorithm, no other positive case was identified in the positive case’s surroundings. Conclusion This study demonstrates that nomadic Peuhls, with a CFA prevalence of 11.9%, pose a potential risk for reintroduction of LF into Togo while Ghanaian refugees and seasonal economic migrants do not appear to pose a significant risk. Periodic monitoring of migrants, especially the nomadic Peuhl population, is a potential post-validation surveillance approach that could be used to promptly detect any LF cluster that may arise.

scholarly journals Progress towards elimination of lymphatic filariasis in the Americas region

2020 ◽  
Vol 13 (Supplement_1) ◽  
pp. S33-S38
Author(s):  
Gilberto Fontes ◽  
Eliana Maria Mauricio da Rocha ◽  
Ronaldo Guilherme Carvalho Scholte ◽  
Rubén Santiago Nicholls
Keyword(s):  
Dominican Republic ◽  
Lymphatic Filariasis ◽  
Wuchereria Bancrofti ◽  
World Health ◽  
Vector Species ◽  
Effective Coverage ◽  
The Third ◽  
Assessment Survey ◽  
Health Organization ◽  
Important Progress

Abstract In South and Central America, lymphatic filariasis (LF) is caused by Wuchereria bancrofti, which is transmitted by Culex quinquefasciatus, the only vector species in this region. Of the seven countries considered endemic for LF in the Americas in the last decade, Costa Rica, Suriname and Trinidad and Tobago were removed from the World Health Organization list in 2011. The remaining countries, Brazil, Dominican Republic, Guyana and Haiti, have achieved important progress in recent years. Brazil was the first country in the Americas to stop mass drug administration (MDA) and to establish post-MDA surveillance. Dominican Republic stopped MDA in all LF-endemic foci: La Ciénaga and Southwest passed the third Transmission Assessment Survey (TAS) and the Eastern focus passed TAS-1 in 2018. Haiti passed the TAS and interrupted transmission in &gt;80% of endemic communes, achieving effective drug coverage. Guyana implemented effective coverage in MDAs in 2017 and 2018 and in 2019 scaled up the treatment for 100% of the geographical region, introducing ivermectin in the MDA in order to achieve LF elimination by the year 2026. The Americas region is on its way to eliminating LF transmission. However, efforts should be made to improve morbidity management to prevent disability of the already affected populations.

Sign in / Sign up

Export Citation Format

Share Document