scholarly journals Correction to: Determinants of none-exclusive breast feeding practice among HIV positive women at selected Health Institutions in Ethiopia: case control study

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Aklilu Abera Ayele ◽  
Kemal Ahmed Seid ◽  
Oumer Sada Muhammed
Keyword(s):  
Breast Feeding ◽  
Case Control Study ◽  
Case Control ◽  
Hiv Positive ◽  
Feeding Practice ◽  
Exclusive Breast Feeding ◽  
Hiv Positive Women ◽  
Health Institutions ◽  
Control Study

scholarly journals Association between use of the progestin Depot Medroxyprogesterone Acetate and Cervicovaginal Lavage Proinflammatory Cytokines among HIV-1 and HSV-2 co-infected African women: a case control study

2016 ◽  
Author(s):  
Edwin Walong ◽  
Christopher Gontier ◽  
Walter Jaoko ◽  
Elizabeth Bukusi
Keyword(s):  
Proinflammatory Cytokines ◽  
Medroxyprogesterone Acetate ◽  
Case Control Study ◽  
Case Control ◽  
Hiv Positive ◽  
Regulatory Cytokine ◽  
Hiv Positive Women ◽  
Cervicovaginal Lavage ◽  
Hiv 1 ◽  
Control Study

ABSTRACTBackgroundUse of the progestin contraceptive Depot Medroxyprogesterone Acetate (DMPA) by HIV 1 infected women is associated with increased female to male transmission of HIV. Mucosal innate immune activation has been proposed as a likely mechanism. To establish the effect of DMPA upon mucosal immune activation, this study sought to evaluate the concentrations of 5 proinflammatory and the regulatory cytokine IL 10 in cervicovaginal lavage fluid.MethodsThis was a case control study, 70 participants were recruited, comprising of 35 asymptomatic ART naïve HIV positive women on DMPA recruited as cases and 35 age matched asymptomatic ART naive HIV positive women not on contraceptives recruited as controls. Peripheral blood CD4 and total lymphocyte counts, High vaginal swab microscopy, endocervical smears and cervical cytology were performed for each participant. Concentrations of six proinflammatory cytokines were measured on cervicovaginal lavage by multiplex cytometric bead array.ResultsThe mean age of cases was 26.8 years and 30 years for controls. Total lymphocyte counts and CD4 cell counts were significantly higher among cases (p=0.02 and 0.004 respectively). HSV 2 prevalence as determined by ELISA was higher (p=0.034 among cases. The concentrations of the cytokines IL 1β, IL 6, IL 8, IL 12p70 and TNF α were lower among cases, with IL 1β being statistically significant (p=0.046). Concentrations of IL 10 was higher among cases (p=0.022). On multivariate analysis, reduction in IL 1β and IL 8 were associated with the duration of DMPA use (p=0.015 and 0.041 respectively). Inclusion of HSV 2 into the multivariate models showed elevation of all cytokines measured (p=<0.001).ConclusionDMPA use is associated with reduction of proinflammatory cytokines and elevation of the regulatory cytokine IL 10. This may explain increased female to male transmission of HIV infection by modulation of male genital tract mucosa in the absence of increased HIV 1 genital shedding.

scholarly journals Risk Factors of Stunting Among Children Aged 6-59 Months In Bensa District ISTRICT, Sidama Region, South Ethiopia: Unmatched Case-Control Study

2021 ◽  
Author(s):  
TEMESGEN TAFESSE ◽  
AMANUEL YOSEPH ◽  
KALEB MAYISO ◽  
TAYE GARI
Keyword(s):  
Risk Factors ◽  
Breast Feeding ◽  
Formal Education ◽  
Case Control Study ◽  
Case Control ◽  
Exclusive Breast Feeding ◽  
Under Five ◽  
South Ethiopia ◽  
Male Sex ◽  
Control Study

Abstract Background: Stunting remains one of the most common under-nutrition problems among children in the Ethiopia. Children aged 6-59 months share for 35–45% of the burden in endemic areas. Identifying the causes of stunting assists health planners to prioritize prevention strategies, and is a fundamental step for intervention. However, evidence scarce about risk factors of stunting among children aged 6-59 months in study area. Therefore, this study aimed to assess risk factors of stunting among children aged 6-59 months in Bensa district, South Ethiopia; 2019. Methods: A facility-based unmatched case-control study was conducted from January 10 to March 10, 2018 on a sample of 237(79 cases and 158 controls) children aged 6-59 months with their respective mothers. Data were collected using a structured, face-to-face interviewer-administered questionnaire and standard physical measurements. The data were entered using EPINFO version 7 and WHO Anthro software version 3.0.1 and analyzed using SPSS version 20. Chi-square(X2) test was used to determine the overall association between explanatory and outcome variables. The variables were entered to the multivariable model using the backward stepwise regression approach. Multivariable logistic regression analysis was used to identify factors associated with stunting. Adjusted odds ratios (AORs) with a 95% confidence interval (CI) were computed to evaluate the presence and strength of associations. Results: Diarrhea in past two weeks (AOR = 2.71, 95% CI: 1.42-5.16) and male sex (AOR = 2.37, 95% CI: 1.224-4.59) were positively associated with stunting. The odds of stunting increased 2.7 times for children who had inappropriate exclusive breast feeding (AOR =2.07, 95%CI: 1.07-4.01) as compared to those who had the appropriate exclusive breast feeding. Having less than or equal to three under five children in the household (AOR = 2.18, 95%CI: 03-4.64), and mothers had no formal education (AOR =3.28, 95%CI: 1.56-6.924) were positively associated with stunting. Conclusions: Male sex, diarrhea in past two weeks, inappropriate exclusive breast feeding, number of the under five children in the household and mothers had no formal education were major predictors of the stunting. Educating mothers/care takers on Infant and Young Child Feeding practice. Findings support a focus on prevention of diarrhea as part of an overall public health strategy for improving child health and nutrition.

Meconium aspiration syndrome in infants of HIV-positive women: a case-control study

2016 ◽  
Vol 44 (4) ◽  
Author(s):  
Sachin K. Gupta ◽  
Pam Haerr ◽  
Richard David ◽  
Alok Rastogi ◽  
Suma Pyati
Keyword(s):  
Case Control Study ◽  
Meconium Aspiration Syndrome ◽  
Case Control ◽  
Hiv Positive ◽  
Meconium Aspiration ◽  
Hiv Positive Women ◽  
Maternal Hiv ◽  
Maternal Hiv Infection ◽  
Control Study ◽  
Hiv Negative

AbstractOur aim was to determine whether maternal HIV infection in the current era is associated with an increased incidence of meconium aspiration syndrome (MAS) in their infants.Infants born to 149 HIV-positive women at our hospital over a 5-year period were compared with infants born to HIV-negative women in a retrospective case-control study. Charts of all 298 patients included in the study were reviewed for maternal and infant demographics, HIV treatment, vertical transmission and untoward events at delivery or during the hospital course.When compared with HIV-negative women, a greater proportion of HIV-positive women had meconium-stained amniotic fluid (MSAF), 33% vs. 13%, P<0.001; and thick MSAF, 17% vs. 5%, P<0.001, respectively. Seven of 298 infants were admitted to the neonatal intensive care unit for MAS; all seven were born to HIV-positive women (P=0.015). AlthoughInfants born to HIV-positive women had significantly more MSAF and MAS than infants born to non-infected women. It is unclear whether this association results from maternal HIV infection itself or from anti-retroviral therapy. Maternal and infant care providers should be prepared for this complication when attending to the deliveries of HIV-positive women.

scholarly journals Characteristics of HIV-positive pregnant women and HIV- and antiretroviral therapy-exposed fetuses: A case-control study

2020 ◽  
Vol 14 (08) ◽  
pp. 901-907
Author(s):  
Tung-Che Hung ◽  
Li-Cheng Lu ◽  
Mei-Hui Lin ◽  
Yu-Chia Hu ◽  
Chien-Yu Cheng ◽  
...  
Keyword(s):  
Body Weight ◽  
Antiretroviral Therapy ◽  
Pregnant Women ◽  
Case Control Study ◽  
Case Control ◽  
Hiv Positive ◽  
Positive Group ◽  
Hiv Positive Women ◽  
Control Study ◽  
Hiv Negative

Introduction: This study determined risk factors, obstetric comorbidities, and fetal conditions among HIV-positive mothers to improve their maternal care. Methodology: This retrospective case-control study included HIV-positive pregnant women 18 years of age or older and age-, parity-, and delivery method-matched HIV-negative controls between 2011 and 2018. Those who had stillbirth were excluded. Baseline demographics, labor process, CD4 count, plasma HIV viral load, and antiretroviral therapy (ART) regimen were recorded. Fetal conditions were recorded as well. Results: Forty HIV-positive women (45 parities; 22 via NSD, 23 via C/S) were included, with 45 HIV-negative parities as controls. Twenty-nine (72.5%) HIV-positive women had illicit drug use. In the HIV-positive group, 17% received ART prior to first perinatal visit, and 75.6% reached viral suppression pre-delivery. Zidovudine and ritonavir-boosted lopinavir were the majorly prescribed ART. Mild perineal lacerations via NSD were observed in HIV-positive women. Fetal body weight was lower in HIV- and ART-exposed fetuses (2665 vs 3010 g, p < 0.001). Preterm delivery PTB (28.9% vs 8.9%, p= 0.015) and small-for gestational age SGA (28.9% vs 8.8%, p = 0.003) rates were higher in the HIV-positive group. There was no vertical transmission of HIV. Conclusions: HIV-positive women tend to deliver fetuses with low body weight and have higher SGA and PTB rates. Given that most women received zidovudine and protease inhibitors, benefits of newer agents for HIV-positive pregnancies should be studied.

scholarly journals Risk factors for severe acute malnutrition in under-five children attending nutritional rehabilitation centre of tertiary teaching hospital in Karnataka: a case control study

2017 ◽  
Vol 4 (5) ◽  
pp. 1721 ◽  
Author(s):  
M. R. Prashanth ◽  
Savitha M. R. ◽  
Prashantha B.
Keyword(s):  
Risk Factors ◽  
Breast Feeding ◽  
Case Control Study ◽  
Severe Acute Malnutrition ◽  
Case Control ◽  
Acute Malnutrition ◽  
Nutritional Rehabilitation ◽  
Rehabilitation Centre ◽  
Exclusive Breast Feeding ◽  
Control Study

Background: To determine and analyse the risk factors leading to severe acute malnutrition (SAM) in children under 5 years of age attending nutritional rehabilitation centre of our hospital.Methods: This questionnaire based case control study was conducted from January 2016 to December 2016 on SAM children. For comparison children attending outpatient department without any evidence of malnutrition were included. These SAM children were admitted to the nutritional rehabilitation centre of Cheluvamba Hospital attached to Mysore Medical College and Research Institute, Mysore, Karnataka.Results: A total of 103 SAM cases were compared with 100 controls. The sociodemographic risk factors were age less than 2 yrs, more family members (55.3% had 5 to 8 members), Birth spacing less than 2 years (39.8%), open air defecation (37.9%) and living in kucha house (32%). The dietary risk factors which were statistically significant were poor appetite (33%), prelacteal feed (19.4%), lack of exclusive breast feeding (42.7%), discontinuing breast feed before 2 years (74.8%), receiving complementary feed before 6 months (67%), bottle feeding (32%), calorie deficit (79.6%), protein deficit (66%) and feeding difficulty (17.5%).Conclusions: The social risk factors identified in this study were large family size, low income, more number of siblings and living standards like type of house, open air defecation. The nutritional risk factors were giving prelacteal feed, not giving exclusive breast feeding until 6 months, starting complementary feed before 6 months and giving food low in calories and protein.

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