scholarly journals MPDB 2.0: a large scale and integrated medicinal plant database of Bangladesh

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Nazmul Hussain ◽  
Rony Chanda ◽  
Ruhshan Ahmed Abir ◽  
Mohsina Akter Mou ◽  
Md. Kamrul Hasan ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Large Scale ◽  
Folk Medicine ◽  
Aloe Vera ◽  
Terminalia Chebula ◽  
Cadmium Level ◽  
Amaranthus Cruentus ◽  
Health Practitioners ◽  
User Friendly ◽  
World Development

Abstract Objective MPDB 2.0 is built to be the continuation of MPDB 1.0, to serve as a more comprehensive data repertoire for Bangladeshi medicinal plants, and to provide a user-friendly interface for researchers, health practitioners, drug developers, and students who wish to study the various medicinal & nutritive plants scattered around Bangladesh and the underlying phytochemicals contributing to their efficacy in Bangladeshi folk medicine. Results MPDB 2.0 database (https://www.medicinalplantbd.com/) comprises a collection of more than five hundred Bangladeshi medicinal plants, alongside a record of their corresponding scientific, family, and local names together with their utilized parts, information regarding ailments, active compounds, and PubMed ID of related publications. While medicinal plants are not limited to the borders of any country, Bangladesh and its Southeast Asian neighbors do boast a huge collection of potent medicinal plants with considerable folk-medicinal history compared to most other countries in the world. Development of MPDB 2.0 has been highly focused upon human diseases, albeit many of the plants indexed here can serve in developing biofuel (e.g.: Jatropha curcas used in biofuel) or bioremediation technologies (e.g.: Amaranthus cruentus helps to reduce cadmium level in soil) or nutritive diets (Terminalia chebula can be used in nutritive diets) or cosmetics (Aloe vera used in cosmetics), etc.

scholarly journals MPDB 2.0: A Large Scale and Integrated Medicinal Plant Database of Bangladesh

2021 ◽  
Author(s):  
Nazmul Hussain ◽  
Rony Chando ◽  
Ruhshan Ahmed Abir ◽  
Mohsina Akter Mou ◽  
Md. Kamrul Hasan ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Large Scale ◽  
East Asian ◽  
Folk Medicine ◽  
Human Diseases ◽  
Health Practitioners ◽  
The World ◽  
Medicine History ◽  
User Friendly

Medicinal plants are generally defined as rare herbals with potent medicinal activities that can be used as an alternative treatment for diseases. Recent studies exploring novel medicine developments, originating from folk-medicinal practices challenges this notion and suggests that both the circumference of the term medicinal plant and their potential application covers a substantially extensive verse than previously suggested. While medicinal plants are not limited to the borders of any country, Bangladesh and its south-east Asian neighbors do boast a huge collection of potent medicinal plants with considerable folk-medicine history compared to most other countries of the world. MPDB 2.0 is the continuation of MPDB 1.0, it serves as both a data repertoire for medicinal of Bangladesh and a user-friendly interface for researchers, health practitioners, drug developers, and students who wish to study the various medicinal & nutritive plants scattered around Bangladesh and the underlying phytochemicals contributing to their efficacy in folk medicine. While in developing MPDB 2.0 human diseases have been highly focused upon, the information in this database is not limited in its application for human diseases or diseases only, as many of the plants indexed here can serve in developing biofuel or bioremediation technologies or nutritive diets or cosmetics, etc. MPDB 2.0 comprises a collection of more than five hundred medicinal plants from Bangladesh along with a record of their corresponding scientific, family, and local names together with their utilized parts, information regarding ailments, active compounds, and PubMed ID of related publications.

scholarly journals Pharmacognostic Properties of Quisqualis indica Linn: Against Human Pathogenic Microorganisms: An Insight Review

2020 ◽  
pp. 87-103
Author(s):  
Braja Sundar Barik ◽  
Shritam Das ◽  
Tahziba Hussain
Keyword(s):  
Medicinal Plants ◽  
Large Scale ◽  
Aloe Vera ◽  
Ocimum Sanctum ◽  
Santalum Album ◽  
Pathogenic Microorganisms ◽  
Nepeta Cataria ◽  
Wide Range ◽  
Medicinal Properties ◽  
Anti Fungal

India has a large repository of medicinal plants that are used in traditional medical treatments. Several medicinal plants are useful for treating common ailments and some of the plants include Amla (Emblica cinalis), Ashoka (Saraca asoca), Aswagandha (Withania somnifera), Tulsi (Ocimum sanctum), Sarpa Gandha (Rauwolfia serpentina), Sandalwood (Santalum album), Indian birthwort (Aristolochia indica L.), Brahmi (Bacopa monnieri), Neem (Azardirchata indica), Vringraj (Eclipta alba), Grhit kumara (Aloe vera), Harida (Terminalia chebula) and Madhumalati (Quisqualis indica), Catnip (Nepeta cataria), Cayenne pepper (Capsicum annuum), Sage (Salvia officinalis); etc. Quisquails indica commonly known as the Madhu Malati, is a vine with red flower clusters and is found in abundance in India. It shows a wide range of remarkable medicinal properties. Over the last two decades, large scale research has been conducted to identify bio-active constituents of Quisqualis indica therapeutic prospects. This review summarizes the pharmacognostic properties of Quisqualis indica Linn. Against human pathogenic microorganisms. Several authors have reviewed the medicinal properties of Quisqualis indica Linn.but our review summarizes the anti-bacterial, anti-inflammatory, anti-oxidant, anti-pyretic, anti-helminthic, anti-diarrheal, anti-hyperglycemic, anti-microbial, anti-fungal and immuno-modulatory properties. It would be useful to students, academicians, microbiologists, as it reduces the need for detailed searching. It serves the purpose of quick reference.

scholarly journals Antileishmanial Activity of Medicinal Plants Used in Endemic Areas in Northeastern Brazil

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Aline Cavalcanti De Queiroz ◽  
Thays de Lima Matos Freire Dias ◽  
Carolina Barbosa Brito Da Matta ◽  
Luiz Henrique Agra Cavalcante Silva ◽  
João Xavier de Araújo-Júnior ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Folk Medicine ◽  
Aloe Vera ◽  
Northeastern Brazil ◽  
Ruta Graveolens ◽  
Chenopodium Ambrosioides ◽  
Leishmanicidal Activity ◽  
Pfaffia Glomerata ◽  
Ldh Assay ◽  
Endemic Areas

This study investigates the leishmanicidal activity of five species of plants used in folk medicine in endemic areas of the state of Alagoas, Brazil. Data were collected in the cities of Colonia Leopoldina, Novo Lino, and União dos Palmares, Alagoas state, from patients with cutaneous leishmaniasis (Leishmania amazonensis) who use medicinal plants to treat this disease. Plants extracts were tested at a concentration of 1–100 μg/mL in all experiments, except in an assay to evaluate activity against amastigotes, when 10 μg/mL was used. All plants extracts did not show deleterious activity to the host cell evidenced by LDH assay at 100, 10, and 1 μg/mL after 48 h of incubation. The plants extractsHyptis pectinata(L.) Poit,Aloe veraL.,Ruta graveolensL.,Pfaffia glomerata(Spreng.) Pedersen, andChenopodium ambrosioidesL. exhibited direct activity against extracellular forms at 100 μg/mL; these extracts inhibited growth by 81.9%, 82.9%, 74.4%, 88.7%, and 87.4%, respectively, when compared with promastigotes. The plants extractsH. pectinata, A. vera,andR. graveolensalso significantly diminished the number of amastigotes at 10 μg/mL, inhibiting growth by 85.0%, 40.4%, 94.2%, and 97.4%, respectively, when compared with control. Based on these data, we conclude that the five plants exhibited considerable leishmanicidal activity.

scholarly journals INFLUENCE OF THE LEVEL OF SOIL POLLUTION WITH HEAVY METALS ON THE INTENSITY OF ACCUMULATION OF THEIR IN LEAVES MILK THISTLE (SÍLYBUM MARIÁNUM)

2019 ◽  
pp. 196-205
Author(s):  
Serhiy Razanov ◽  
Alla Razanova ◽  
Vitaliy Ovcharuk
Keyword(s):  
Medicinal Plants ◽  
Crop Rotation ◽  
Large Scale ◽  
Heavy Metal Contamination ◽  
Folk Medicine ◽  
Forest Steppe ◽  
Milk Thistle ◽  
Field Crop ◽  
Silybum Marianum ◽  
Long Term Treatment

The intensity of heavy metal contamination leaves of milk thistle grown under conditions of field crop rotation of intensive agriculture and on non-cultivated natural lands of the forest steppe of the right bank was studied. Among the plants that have found their application in medicine, medicinal plants in Ukraine are considered to be almost 250 species, including 150 - for traditional medicine, the rest are used only in folk medicine. Traditionally, about 100 species are harvested, of which, on a large scale, 40 to 50 species. Possibilities of application of medicinal plants are quite significant. The efficacy and safety of herbal preparations can be used in long-term treatment of patients of different age groups. As a medicinal plant of milk thistle (Sílybum Mariánum) has been used since ancient times, it is the source of exceptional therapeutic ingredients that play a positive role in the treatment of liver disease. Practical value in the structure of the crop of this plant have the fruits, although in folk medicine also use juice from grass and root. Milk thistle is known and as a food plant, has a forage value, in beekeeping is defined as a fairly good honey plant. Milk thistle grass is used as green fertilizer and for bookmarking compost. According to the results of the conducted researches, it was found that in the leaf of thistle spotted crops grown in conditions of field crop rotation intensive farming, a higher concentration of Pb was observed in 1.66 times, Cd - 1.05 times, Cu - 1.56 times, Zn - in 1.34 times compared with similar raw materials obtained in conditions of non-cultivated natural lands.

Naphthoquinones and derivatives for chemotherapy: perspectives and limitations of their anti-trypanosomatids activities

2020 ◽  
Vol 26 ◽  
Author(s):  
Luíza Dantas-Pereira ◽  
Edézio F. Cunha-Junior ◽  
Valter V. Andrade-Neto ◽  
John F. Bower ◽  
Guilherme A. M. Jardim ◽  
...  
Keyword(s):  
Large Scale ◽  
Neglected Tropical Diseases ◽  
Folk Medicine ◽  
Leishmania Species ◽  
Parasitic Infections ◽  
Mechanistic Analysis ◽  
Leishmania Spp ◽  
Nanomolar Range

: Chagas disease, Sleeping sickness and Leishmaniasis, caused by trypanosomatids Trypanosoma cruzi, Trypanosoma brucei and Leishmania spp., respectively, are considered neglected tropical diseases, and they especially affect impoverished populations in the developing world. The available chemotherapies are very limited and a search for alternatives is still necessary. In folk medicine, natural naphthoquinones have been employed for the treatment of a great variety of illnesses, including parasitic infections. This review is focused on the anti-trypanosomatid activity and mechanistic analysis of naphthoquinones and derivatives. Among all the series of derivatives tested in vitro, naphthoquinone-derived 1,2,3-triazoles were very active on T. cruzi infective forms in blood bank conditions, as well as in amastigotes of Leishmania spp. naphthoquinones containing a CF3 on a phenyl amine ring inhibited T. brucei proliferation in the nanomolar range, and naphthopterocarpanquinones stood out for their activity on a range of Leishmania species. Some of these compounds showed a promising selectivity index (SI) (30 to 1900), supporting further analysis in animal models. Indeed, high toxicity to the host and inactivation by blood components are crucial obstacles to be overcome to use naphthoquinones and/or their derivatives for chemotherapy. Multidisciplinary initiatives embracing medicinal chemistry, bioinformatics, biochemistry, and molecular and cellular biology need to be encouraged to allow the optimization of these compounds. Large scale automated tests are pivotal for the efficiency of the screening step, and subsequent evaluation of both the mechanism of action in vitro and pharmacokinetics in vivo are essential for the development of a novel, specific and safe derivative, minimizing adverse effects.

Phytotherapy for wound healing: The most important herbal plants in wound healing based on Iranian etnobotanical documents

2020 ◽  
Vol 20 ◽  
Author(s):  
Kamal Solati ◽  
Mehrdad Karimi ◽  
Mahmoud Rafieian-Kopaei ◽  
Naser Abbasi ◽  
Saber Abbaszadeh ◽  
...  
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Aloe Vera ◽  
Datura Stramonium ◽  
New Drugs ◽  
Mentha Pulegium ◽  
Accelerate Wound Healing ◽  
Healing Tissue ◽  
Herbal Plants ◽  
Echium Amoenum

: Wound healing is a process which starts with inflammatory response after damage occurrence. This process happens by restoring the wound surface coating tissue, migrating fibroblasts to form the needed collagen, forming a healing tissue and finally contortion and extraction of the wound. Today, various drugs are used to heal the wound. However, the used drugs to repair wounds have some defects and side effects. In spite of all attempts to accelerate wound healing definitely, no safe drug has been introduced for this purpose. Therefore, the necessity of identifying herbal plants in ethnopharmacology and ethnobotany documents with healing effect is felt essential. In this article we tried to review and present Iranian effective medicinal plants and herbal compounds used for wound healing. Searching was performed on databases including ISI Web of Science, PubMed, PubMed Central, Scopus, ISC, SID, Magiran and some other databases. The keywords used included wound healing, skin treatment, medicinal plants, ethnobotany, and phytotherapy. In this regard, 139 effective medicinal plants on wound healing were identified based on ethnopharmacology and ethnobotanical sources of Iran. Medicinal plants such as Salvia officinalis, Echium amoenum, Verbascum spp., G1ycyrrhiza glabra, Medicago sativa, Mentha pulegium, Datura stramonium L., Alhagi spp., Aloe vera, Hypericum perforatum, Pistacia atlantica and Prosopis cineraria were the most important and effective medicinal plants on wound healing in Iran. These native Iranian medicinal plants are full of antioxidants and biological compounds and might be used for wound healing and preparation of new drugs.

Microcomputer Simulations of Presidential Elections

1983 ◽  
Vol 38 ◽  
pp. 20-20
Author(s):  
Robert S. Ross
Keyword(s):  
Social Sciences ◽  
Large Scale ◽  
Role Playing ◽  
Science Students ◽  
Instructional Programs ◽  
Santa Barbara ◽  
Large Scale Systems ◽  
The Social ◽  
User Friendly ◽  
Machine Interaction

Simulations have been an important adjunct to instructional programs for some time. These have ranged from games, or role playing exercises, such as SIMSOC or Internation Simulation, to student-machine interaction, such as the inter-school simulation run out of University of California, Santa Barbara in the early 70's, to the all machine activities found in some of the early SETUPS. Having social science students use the mainframe computer, however, always posed problems: it definitely was not user-friendly and most instructors had little if any training or interest in the use of large scale systems.The wide-spread use of the micro computer is not only revolutionizing areas traditionally relying upon the computer, but is going to have an impact on the social sciences as well.

scholarly journals fastER: a user-friendly tool for ultrafast and robust cell segmentation in large-scale microscopy

2017 ◽  
Vol 33 (13) ◽  
pp. 2020-2028 ◽  
Author(s):  
Oliver Hilsenbeck ◽  
Michael Schwarzfischer ◽  
Dirk Loeffler ◽  
Sotiris Dimopoulos ◽  
Simon Hastreiter ◽  
...  
Keyword(s):  
Large Scale ◽  
Cell Segmentation ◽  
User Friendly

scholarly journals Pharmacological and Ethnomedicinal Overview of Heritiera fomes: Future Prospects

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Imran Mahmud ◽  
Md Khirul Islam ◽  
Sanjib Saha ◽  
Apurba Kumar Barman ◽  
Md Mustafizur Rahman ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Anticancer Activities ◽  
Mangrove Plant ◽  
River Deltas ◽  
Traditional Health ◽  
Heritiera Fomes ◽  
Health Practitioners ◽  
Important Medicinal Plant

Mangrove plants are specialized woody plants growing in the swamps of tidal-coastal areas and river deltas of tropical and subtropical parts of the world. They have been utilized for medicinal and other purposes by the coastal people over the years. Heritiera fomes Buch. Ham. (family: Sterculiaceae) commonly known as Sundari (Bengali) is a preeminent mangrove plant occurring in the Sundarbans forest located in the southern part of Bangladesh and adjoining West Bengal province of India. The plant has applications in traditional folk medicine as evidenced by its extensive use for treating diabetes, hepatic disorders, gastrointestinal disorders, goiter, and skin diseases by the local people and traditional health practitioners. A number of investigations indicated that the plant possesses significant antioxidant, antinociceptive, antihyperglycemic, antimicrobial, and anticancer activities. Phytochemical analyses have revealed the presence of important chemical constituents like saponins, alkaloids, glycosides, tannins, steroids, flavonoids, gums, phytosterols, and reducing sugars. The present study is aimed at compiling information on phytochemical, biological, pharmacological, and ethnobotanical properties of this important medicinal plant, with a view to critically assess the legitimacy of the use of this plant in the aforementioned disorders as well as providing directions for further research.

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