scholarly journals Graphene oxide modified screen-printed electrode for highly sensitive and selective electrochemical detection of ciprofloxacin residues in milk

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Ming Pan ◽  
Peipei Guo ◽  
Haifeng Liu ◽  
Jiawei Lu ◽  
Qiubo Xie
Keyword(s):  
Graphene Oxide ◽  
Milk Sample ◽  
Residue Analysis ◽  
Correlation Coefficients ◽  
Current Response ◽  
Peak Current ◽  
Screen Printed Carbon Electrode ◽  
Highly Sensitive ◽  
Relative Standard ◽  
Screen Printed

AbstractThe monitoring of antibiotic residues in foodstuffs by using rapid detection method is essential for food safety. In this work, the electrochemical sensor was developed by modification of screen-printed carbon electrode with graphene oxide, and then the ciprofloxacin (CIP) was detected based on the complexation of CIP with Mn2+. On modified electrode, the anodic stripping peak current response of Mn2+ was prohibited in the presence of CIP, and a peak current response of the complex was occurred. Thus, the peak current response of the complexation peak was employed as the indicating signal for CIP determination, which was more sensitive than the direct electrochemical oxidation response of CIP. Parameters that affect the signal response have been investigated in method. Under the optimum conditions, the peak current of the complexation peak was linearly correlated with the CIP content in the milk sample solution at 1.0 to 8.0 μM, and the linear correlation coefficients (R2) was 0.994. The limits of detection (LOD) was 0.30 μM. Recoveries of CIP in milk sample were ranged from 81.0 to 95.4% with relative standard deviations (RSDs) below 4.6%. The method showed high selectivity and sensitive, good reproducibility, indicated that this method has potential to be applied in CIP residue analysis.

scholarly journals Electrochemical Determination of Lead & Copper Ions Using Thiolated Calix[4]arene-Modified Screen-Printed Carbon Electrode

Chemosensors ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 157
Author(s):  
Chong Jin Mei ◽  
Nor Azah Yusof ◽  
Shahrul Ainliah Alang Ahmad
Keyword(s):  
Electrochemical Impedance ◽  
Limit Of Detection ◽  
Copper Ions ◽  
Current Response ◽  
Carbon Electrode ◽  
Significant Drop ◽  
Screen Printed Carbon Electrode ◽  
Relative Standard ◽  
Competitive Ions ◽  
Screen Printed

This study used a thiolated calix[4]arene derivative modified on gold nanoparticles and a screen-printed carbon electrode (TC4/AuNPs/SPCE) for Pb2+ and Cu2+ determination. The surface of the modified electrode was characterised via Fourier-transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). Differential pulse voltammetry (DPV) was used for the detection of Pb2+ and Cu2+ under optimum conditions. The limit of detection (LOD) for detecting Pb2+ and Cu2+ was 0.7982 × 10−2 ppm and 1.3358 × 10−2 ppm, respectively. Except for Zn2+ and Hg2+, the presence of competitive ions caused little effect on the current response when detecting Pb2+. However, all competitive ions caused a significant drop in the current response when detecting Cu2+, except Ca2+ and Mg2+, suggesting the sensing platform is more selective toward Pb2+ ions rather than copper (Cu2+) ions. The electrochemical sensor demonstrated good reproducibility and excellent stability with a low relative standard deviation (RSD) value in detecting lead and copper ions. Most importantly, the result obtained in the analysis of Pb2+ and Cu2+ had good recovery in river water, demonstrating the applicability of the developed sensor for real samples.

scholarly journals A highly sensitive biosensor based on methacrylated graphene oxide-grafted polyaniline for ascorbic acid determination

2020 ◽  
Vol 9 (1) ◽  
pp. 760-767 ◽  
Author(s):  
Seyed Morteza Naghib ◽  
Farahnaz Behzad ◽  
Mehdi Rahmanian ◽  
Yasser Zare ◽  
Kyong Yop Rhee
Keyword(s):  
Ascorbic Acid ◽  
Graphene Oxide ◽  
Current Response ◽  
Functionalized Graphene ◽  
Serum Samples ◽  
Promising Candidate ◽  
Graphene Nanocomposites ◽  
Selective Determination ◽  
Highly Sensitive

AbstractFunctionalized graphene-based nanocomposites have opened new windows to address some challenges for increasing the sensitivity, accuracy and functionality of biosensors. Polyaniline (PANI) is one of the most potentially promising and technologically important conducting polymers, which brings together the electrical features of metals with intriguing properties of plastics including facile processing and controllable chemical and physical properties. PANI/graphene nanocomposites have attracted intense interest in various fields due to unique physicochemical properties including high conductivity, facile preparation and intriguing redox behavior. In this article, a functionalized graphene-grafted nanostructured PANI nanocomposite was applied for determining the ascorbic acid (AA) level. A significant current response was observed after treating the electrode surface with methacrylated graphene oxide (MeGO)/PANI nanocomposite. The amperometric responses showed a robust linear range of 8–5,000 µM and detection limit of 2 µM (N = 5). Excellent sensor selectivity was demonstrated in the presence of electroactive components interfering species, commonly found in real serum samples. This sensor is a promising candidate for rapid and selective determination of AA.

scholarly journals Development of Highly Sensitive Immunosensor for Clenbuterol Detection by Using Poly(3,4-ethylenedioxythiophene)/Graphene Oxide Modified Screen-Printed Carbon Electrode

Sensors ◽  
2018 ◽  
Vol 18 (12) ◽  
pp. 4324 ◽  
Author(s):  
Nurul Talib ◽  
Faridah Salam ◽  
Yusran Sulaiman
Keyword(s):  
Graphene Oxide ◽  
Limit Of Detection ◽  
Food Product ◽  
Electrochemical Immunosensor ◽  
Growth Promoter ◽  
Carbon Electrode ◽  
Electrochemical Assay ◽  
Sensor Platform ◽  
Screen Printed Carbon Electrode ◽  
Screen Printed

Clenbuterol (CLB) is an antibiotic and illegal growth promoter drug that has a long half-life and easily remains as residue and contaminates the animal-based food product that leads to various health problems. In this work, electrochemical immunosensor based on poly(3,4-ethylenedioxythiophene)/graphene oxide (PEDOT/GO) modified screen-printed carbon electrode (SPCE) for CLB detection was developed for antibiotic monitoring in a food product. The modification of SPCE with PEDOT/GO as a sensor platform was performed through electropolymerization, while the electrochemical assay was accomplished while using direct competitive format in which the free CLB and clenbuterol-horseradish peroxidase (CLB-HRP) in the solution will compete to form binding with the polyclonal anti-clenbuterol antibody (Ab) immobilized onto the modified electrode surface. A linear standard CLB calibration curve with R2 = 0.9619 and low limit of detection (0.196 ng mL−1) was reported. Analysis of milk samples indicated that this immunosensor was able to detect CLB in real samples and the results that were obtained were comparable with enzyme-linked immunosorbent assays (ELISA).

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