scholarly journals Findings and measures to eradicate methicillin resistant Staphylococcus aureus clonal complex 7 spa-type t091 in two Norwegian pig farms: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
O. M. Karlsen ◽  
K. D. Sandbu ◽  
C. A. Grøntvedt
Keyword(s):  
Methicillin Resistant Staphylococcus Aureus ◽  
Lower Cost ◽  
Clonal Complex ◽  
Time Interval ◽  
Case Presentation ◽  
Pig Farms ◽  
Longitudinal Sampling ◽  
And Control ◽  
Spa Type

Abstract Background The Norwegian LA-MRSA surveillance and control strategy in pig farms has been largely successful in preventing the establishment of MRSA in the pig population by identifying positive pig herds and eradicating MRSA from these. It can, however, be challenging to determine whether a particular type of MRSA is livestock-associated, particularly in cases where there is little evidence available to aid in classification. Case presentation In two Norwegian pig farms linked by trade of live pigs, MRSA CC7 t091 was found in samples from pigs and their environment. Longitudinal sampling, with a time interval of 25 days, in one farm demonstrated an increase in samples positive for MRSA CC7 t091, supporting a classification of the finding as livestock associated. Measures to eradicate MRSA from both farms were imposed by the National Food Safety Authority. Different measures of MRSA sanitation were applied in the two farms, and MRSA was successfully eradicated from both farms. Conclusions A high-cost, labor intensive and a lower-cost, less labor intensive MRSA eradication protocol, both including total depopulation and repopulation were successful in eradicating MRSA CC7 t091 from two case farms.

scholarly journals Findings and measures to eradicate methicillin resistant Staphylococcus aureus clonal complex 7 spa-type t091 in two Norwegian pig farms: a case report

2020 ◽  
Author(s):  
Odd Magne Karlsen ◽  
Kari Sandbu ◽  
Carl Andreas Grøntvedt
Keyword(s):  
Control Strategy ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Lower Cost ◽  
Clonal Complex ◽  
Time Interval ◽  
Pig Farms ◽  
Longitudinal Sampling ◽  
And Control ◽  
Spa Type

Abstract BackgroundThe Norwegian LA-MRSA surveillance and control strategy in pig farms has been largely successful in preventing the establishment of MRSA in the pig population by identifying MRSA positive pig herds and eradicating MRSA from these. It can, however, be challenging to determine whether a particular type of MRSA is livestock-associated, particularly in cases where there is little evidence available to aid in classification.Case presentationIn two Norwegian pig farms linked by trade of live pigs, MRSA CC7 t091 was found in samples from pigs and their environment. Longitudinal sampling, with a time interval of 25 days, in one farm demonstrated an increase in samples positive for MRSA CC7 t091, supporting a classification of the finding as livestock associated. Measures to eradicate MRSA from both farms were imposed by the National Food Safety Authority. Different measures of MRSA sanitation were applied in the two farms, and MRSA was successfully eradicated from both farms.ConclusionsA high-cost, labor intensive and a lower-cost, less labor intensive MRSA eradication protocol, both including total depopulation and repopulation were successful in eradicating MRSA CC7 t091 from two case farms.

Farm-specific lineages of methicillin-resistant Staphylococcus aureus clonal complex 398 in Danish pig farms

2011 ◽  
Vol 140 (10) ◽  
pp. 1794-1799 ◽  
Author(s):  
C. ESPINOSA-GONGORA ◽  
J. LARSEN ◽  
A. MOODLEY ◽  
J. P. NIELSEN ◽  
R. L. SKOV ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Clonal Complex ◽  
Age Groups ◽  
Epidemiological Studies ◽  
Farm Workers ◽  
Pfge Analysis ◽  
Methicillin Resistant ◽  
Pig Farms ◽  
Single Exception

SUMMARYThe objective of this study was to investigate the genetic diversity of methicillin-resistant Staphylococcus aureus (MRSA) clonal complex (CC) 398 using pulsed-field gel electrophoresis (PFGE). Dust and pigs at five age groups were sampled in six Danish MRSA-positive pig farms. MRSA CC398 was isolated from 284 of the 391 samples tested, including 230 (74%) animal and 54 (68%) environmental samples. PFGE analysis of a subset of 48 isolates, including the six strains previously isolated from farm workers, revealed the existence of farm-specific pulsotypes. With a single exception, human, environmental and porcine isolates originating from the same farm clustered together in the PFGE cluster analysis, indicating that spread of MRSA CC398 in Danish pig farms is mainly due to clonal dissemination of farm-specific lineages that can be discriminated by PFGE. This finding has important implications for planning future epidemiological studies investigating the spread of CC398 in pig farming.

Learning and control

2018 ◽  
Author(s):  
Ivan Herreros
Keyword(s):  
Machine Learning ◽  
Reinforcement Learning ◽  
Brain Function ◽  
Control Strategies ◽  
Learning Problems ◽  
Animal Learning ◽  
Feed Forward Control ◽  
Machine Learning Applications ◽  
And Control

This chapter discusses basic concepts from control theory and machine learning to facilitate a formal understanding of animal learning and motor control. It first distinguishes between feedback and feed-forward control strategies, and later introduces the classification of machine learning applications into supervised, unsupervised, and reinforcement learning problems. Next, it links these concepts with their counterparts in the domain of the psychology of animal learning, highlighting the analogies between supervised learning and classical conditioning, reinforcement learning and operant conditioning, and between unsupervised and perceptual learning. Additionally, it interprets innate and acquired actions from the standpoint of feedback vs anticipatory and adaptive control. Finally, it argues how this framework of translating knowledge between formal and biological disciplines can serve us to not only structure and advance our understanding of brain function but also enrich engineering solutions at the level of robot learning and control with insights coming from biology.

Directed earned value management based on ordered fuzzy numbers

2021 ◽  
pp. 1-14
Author(s):  
Seyed Taha Hossein Mortaji ◽  
Siamak Noori ◽  
Morteza Bagherpour
Keyword(s):  
Fuzzy Numbers ◽  
Lower Cost ◽  
Project Managers ◽  
Value Management ◽  
Monitoring And Control ◽  
Earned Value ◽  
Earned Value Management ◽  
Project Monitoring ◽  
And Control

Earned value management is well-known as the most efficient method of project monitoring and control providing relatively reliable information about the project performance. However, this method requires accurate estimates of the progress of project activities, which are always associated with uncertainties that, if ignored or not addressed well, lead to incorrect results. To address this issue, the application of multi-valued logic, in particular fuzzy logic, in earned value management has recently attracted a lot of attention both in practice and research. This paper introduces directed earned value management (DEVM) in which ordered fuzzy numbers are used to express the so-called uncertainties as well as to capture more information about the trend of the project progress. To evaluate the performance of the proposed method, several numerical examples and a case study are presented. The results reveal that compared to the existing methods, DEVM has a lower computational complexity. Also, it doesn’t suffer from the overestimation effect and as a result, it has a higher ability to express project-specific dynamics. In sum, the proposed method allows project managers to make informed decisions that lead to taking preventive and corrective actions promptly and at a lower cost.

scholarly journals Prevalence and Characteristics of Multidrug-Resistant Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) CC398 Isolated from Quails (Coturnix Coturnix Japonica) Slaughtered for Human Consumption

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 2038
Author(s):  
Vanessa Silva ◽  
Madalena Vieira-Pinto ◽  
Cândido Saraiva ◽  
Vera Manageiro ◽  
Lígia Reis ◽  
...  
Keyword(s):  
Methicillin Resistant Staphylococcus Aureus ◽  
Clonal Complex ◽  
Sccmec Type ◽  
Multidrug Resistant ◽  
Coturnix Japonica ◽  
Human Consumption ◽  
Coturnix Coturnix Japonica ◽  
Genetic Lineages ◽  
Coturnix Coturnix ◽  
Type V

Livestock-associated MRSA (LA-MRSA) is a zoonotic pathogen that has been reported in several animals, and it is often associated with clonal complex (CC) 398. We aimed to isolate MRSA from quails and to characterize their antimicrobial resistance and genetic lineages. One hundred swab samples were recovered from quails at the slaughterhouse. The swabs were inoculated onto CHROMagar™ MRSA agar plates for MRSA isolation. The presence of antimicrobial-resistant genes and virulence factors was investigated by PCR. All strains were typed by MLST, SCCmec-, spa- and agr-typing. From the 100 samples, 29 MRSA were isolated. All strains were resistant to penicillin, cefoxitin, ciprofloxacin, erythromycin and clindamycin and carried the blaZ, mecA, ermB and ermC genes. All strains, except one, showed resistance to tetracycline and harbored the tetM, tetK and tetL genes in different combinations. Twenty strains belonged to ST398 and SCCmec type V, and nine strains belonged to the new ST6831. Twenty-eight out of twenty-nine strains were ascribed to t011 and one to t108. As far as we know, this is the first report of MRSA from quails slaughtered for human consumption. Most strains belonged to ST398-t011, which is the most common LA-MRSA clone found in livestock in Europe.

scholarly journals Successful treatment of hepatic lymphorrhea by percutaneous transhepatic lymphangiography followed by sclerotherapy using OK-432

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Masayuki Kojima ◽  
Masanori Inoue ◽  
Seiichiro Yamamoto ◽  
Toshio Kanai ◽  
Seishi Nakatsuka ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Rare Case ◽  
Intraperitoneal Administration ◽  
Lymphatic Vessels ◽  
Hepatoduodenal Ligament ◽  
Massive Ascites ◽  
Case Presentation ◽  
Successful Case ◽  
Leakage Site ◽  
And Control

Abstract Background Conventional lymphangiography cannot detect leakage sites of hepatic lymphatic vessels. Percutaneous transhepatic lymphangiography can be used to visualize leakage sites, and once the leakage site has been confirmed, effective sclerotherapy can be performed. Case presentation A rare case of intractable hepatic lymphorrhea due to injury of the hepatoduodenal ligament following pancreaticoduodenectomy is reported. Drainage of massive ascites from the drainage tube continued after surgery. Percutaneous transhepatic lymphangiography visualized the intrahepatic lymphatic vessels and the leakage site at the hepatic hilum. An 8-Fr drainage catheter was inserted adjacent to the leakage point under fluoroscopic computed tomography guidance. Repeated sclerotherapy using intraperitoneal administration of OK-432 (picibanil) through the catheter was performed, which exposed the leakage site, and control of the ascites was finally achieved. Conclusions To the best of our knowledge, this is the first successful case of detection of a leakage site using intrahepatic lymphangiography, followed by sclerotherapy using OK-432.

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