scholarly journals Potential risk analysis and experience summarization of unstable factors of cranial fixation devices in neurosurgical operations: three-case reports and systematic review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Gaopeng Cheng ◽  
Shuyu Hao ◽  
Zhifen Ye ◽  
Bao Wang ◽  
Bin Huangpu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Vessel ◽  
Potential Risk ◽  
Case Reports ◽  
Anatomical Location ◽  
Fixation Device ◽  
Case Presentation ◽  
Fixation Devices ◽  
The Stability ◽  
Scalp Laceration

Abstract Background The use of cranial fixation devices in neurosurgery is very common, which is considered to be an important auxiliary method for many craniotomies. However, previous studies have reported complications of using cranial fixation devices, including brain tissue, nerve and blood vessel damage, scalp laceration, subcutaneous hematoma, etc. Some of the complications are serious and even potentially fatal, and the causes of which may be related to the incorrect use of cranial fixation devices. Although there are no serious complications in our review, the cause of that needs to be further summarized and analyzed, as so to minimize the serious consequences caused by the cranial fixation device slippage and ensure the safety of the patients’ surgical procedure. Case presentation In our recent work, we have continuously found three cases of unstable cranial fixation devices, which make us to analyze the possible factors and summarize experience combined with the review of other senior neurosurgeons (more than 3 years of working experience) from different departments of neurosurgery. Conclusions Based on our recent incidents of unstable cranial fixation and the experience of investigating and analyzing senior doctors from different neurosurgery centers, we summarized experience to minimize the risk of unstable cranial fixation. We tried a variety of options, including a safe anatomical location for cranial fixation, teamwork, and communication with anesthesiologists and itinerant nurses, to ensure the stability of the patient’s cranial fixation devices. The data obtained in this survey has great limitations, including the doctor’s personal prejudice and dependence on anecdotal memories. Therefore, the data should be interpreted with caution. However, there are still some modes that can help to better understand the use of safe cranial fixation. Based on the above research and analysis, we have made recommendations that may help neurosurgeons to avoid preventable complications

scholarly journals Potential Risk Analysis and Experience Summarization of Unstable Factors of Cranial Fixation Devices in Neurosurgical Operations

2020 ◽  
Author(s):  
Gaopeng Cheng ◽  
Shuyu Hao2 ◽  
Zhifen Ye ◽  
Bao Wang ◽  
Bin Huangpu ◽  
...  
Keyword(s):  
Risk Analysis ◽  
Recent Work ◽  
Potential Risk ◽  
Surgical Procedure ◽  
Anatomical Location ◽  
Fixation Devices ◽  
The Stability

Abstract BACKGROUND The use of cerebral fixation devices in neurosurgery is very common, which is considered to be an important auxiliary method for many craniotomies. However, previous studies have reported complications of using cerebral fixation devices. Some of the complications are serious and even potentially fatal, and the causes of which may be related to incorrect use of cranial fixation devices. Although there are no serious complications, the cause of that needs to be further summarized and analyzed, as so to minimize the serious consequences caused by the cerebral fixation devices slippage and ensure the safety of the patients’ surgical procedure.METHODS In our recent work, we have continuously found three cases of unstable cerebral fixation devices, which allowed us to analysis the possible factors and summarize experience combined with the review of other senior neurosurgeons from different departments of neurosurgery.RESULTS Based on our recent unstable cranial fixation incidents and the experience of investigating and analyzing senior doctors from different neurosurgery centers, we conducted experience analysis and summary to minimize the risk of unstable cranial fixation pins. We tried a variety of options, including a safe anatomical location for cranial fixation, teamwork and communication with anesthesiologists and itinerant nurses to ensure the stability of the patient’s cerebral fixation devices.CONCLUSIONS The data obtained in this survey has great limitations, including the doctor’s personal prejudice and dependence on anecdotal memories. Therefore, the data should be interpreted with caution. Despite these limitations, there are still some modes that can help to better understand the use of safe skull fixation. Based on the above research and analysis, we have made recommendations that may help avoid preventable complications

scholarly journals Functional Outcomes and Complications of Intramedullary Fixation Devices for Midshaft Clavicle Fractures: A Systematic Review and Meta-Analysis.

2020 ◽  
Author(s):  
Paul Hoogervorst ◽  
Tess van Dam ◽  
Nico Verdonschot ◽  
Gerjon Hannink
Keyword(s):  
Systematic Review ◽  
Functional Outcomes ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Intramedullary Fixation ◽  
Common Complication ◽  
Fixation Device ◽  
Operative Strategy ◽  
Fixation Devices ◽  
Clavicle Fractures

Abstract Background An alternative to the current gold standard in operative treatment of displaced midshaft clavicle fractures (DMCF) using plate osteosynthesis, is internal fixation by means of intramedullary fixation devices. These devices differ considerably in their specifications and characteristics. The aim of this systematic review is to generate an overview of functional outcomes and complications in the management of DMCF per available intramedullary device.Methods A systematic review was conducted to identify all papers reporting functional outcomes, union rates and/or complications using an intramedullary fixation device for the management of midshaft clavicle fractures. Multiple databases and trial registries were searched from inception until February 2020. Meta-analysis was conducted based on functional outcomes and type of complication per type of intramedullary fixation device. Pooled estimates of functional outcomes scores and incidence of complications were calculated using a random effects model. Risk of bias and quality was assessed using the Cochrane risk of bias and ROBINS-I tools. The confidence in estimates were rated and described according to the recommendations of the GRADE working group.Results Sixty-seven studies were included in this systematic review. The majority of studies report on the use of Titanium Elastic Nails (TEN). At 12 months follow up the Titanium Elastic Nail and Sonoma CRx report an average Constant-Murley score of 94.4 (95%CI 93-95) and 94.0 (95%CI 92-95) respectively (GRADE High). The most common reported complications after intramedullary fixation are implant-related and implant-specific. For the TEN, hardware irritation and protrusion, telescoping or migration, with a reported pooled incidence 20% (95%CI 14-26) and 12% (95%CI 8-18), are most common (GRADE Moderate). For the Rockwood/Hagie Pin, hardware irritation is identified as the most common complication with 22% (95%CI 13-35) (GRADE Low). The most common complication for the Sonoma CRx was cosmetic dissatisfaction in 6% (95%CI 2-17) of cases (GRADE Very low). Conclusion Although most studies were of low quality, good functional results and union rates irrespective of the type of device are found. However, there are clear device-related and device-specific complications for each. The results of this systematic review and meta-analysis can help guide surgeons in choosing the appropriate operative strategy, implant and informing their patient.

Early survival following in utero myocardial infarction

2018 ◽  
Vol 28 (10) ◽  
pp. 1079-1087
Author(s):  
Peter Cosgrove ◽  
Shan Modi ◽  
Karla Lawson ◽  
Camille Hancock-Friesen ◽  
Gregory Johnson
Keyword(s):  
Myocardial Infarction ◽  
Systematic Review ◽  
Case Reports ◽  
Current Data ◽  
Treatment Modalities ◽  
Case Presentation ◽  
Coronary Imaging ◽  
Prisma Statement ◽  
Short Term Mortality ◽  
Low Threshold

AbstractIntrauterine myocardial infarction is a rare and frequently fatal diagnosis. It has been presented in the literature only as case reports and short series. We present a case report of a coronary occlusive intrauterine myocardial infarction and survival and present a systematic review of the literature. This is the first summative description of current data on intrauterine and perinatal myocardial infarction. We performed the systematic review based on the guidelines established by the PRISMA statement. Our population of intrauterine and perinatal myocardial infarction included published cases who presented as a live birth within the first 28 postnatal days, and had a diagnosis of myocardial infarction. We conducted descriptive statistics and regression analysis on short-term mortality as the primary outcome. After applying exclusion criteria we described 84 individual cases of myocardial infarction from 63 full-text articles including our own case. Presentation within the first 12 hours was associated with mortality (OR 3.90, p=0.004). Treatment modalities were varied and inconsistently recorded. The aetiologies and comorbidities are varied in our systematic review. We would have a low threshold to perform viral testing, consider anticoagulation early and coronary imaging if feasible. The use of extracorporeal membranous oxygenation may serve as a bridge to cardiac recovery.

scholarly journals Recurrent SARS-CoV-2 infections and their potential risk to public health – a systematic review

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261221
Author(s):  
Seth Kofi Abrokwa ◽  
Sophie Alice Müller ◽  
Alba Méndez-Brito ◽  
Johanna Hanefeld ◽  
Charbel El Bcheraoui
Keyword(s):  
Public Health ◽  
Systematic Review ◽  
Recurrence Rate ◽  
Potential Risk ◽  
Observational Studies ◽  
Case Reports ◽  
Relevant Literature ◽  
Contact Tracing ◽  
Epidemiological Characteristics

Objective To inform quarantine and contact-tracing policies concerning re-positive cases—cases testing positive among those recovered. Materials and methods We systematically reviewed and appraised relevant literature from PubMed and Embase for the extent of re-positive cases and their epidemiological characteristics. Results In 90 case reports/series, a total of 276 re-positive cases were found. Among confirmed reinfections, 50% occurred within 90 days from recovery. Four reports related onward transmission. In thirty-five observational studies, rate of re-positives ranged from zero to 50% with no onward transmissions reported. In eight reviews, pooled recurrence rate ranged from 12% to 17.7%. Probability of re-positive increased with several factors. Conclusion Recurrence of a positive SARS-CoV-2 test is commonly reported within the first weeks following recovery from a first infection.

scholarly journals Comparative analysis of modeled femoral fractures osteosynthesis stability

2014 ◽  
Vol 95 (3) ◽  
pp. 392-394
Author(s):  
O N Yamshchikov ◽  
D A Markov ◽  
S A Emelyanov ◽  
K P Zvereva ◽  
A E Bychkov
Keyword(s):  
External Fixation ◽  
Axial Load ◽  
Test Machine ◽  
Fixation Device ◽  
Intramedullary Nails ◽  
Fixation Devices ◽  
Bone Fragments ◽  
Angle Stability ◽  
External Fixation Device ◽  
The Stability

Aim. To perform the comparative analysis of osteosynthesis stability in splintered fractures on the example of modeled fractures of femur with metalwork. Methods. Bone fragments fixation methods using internal fixators, blocking intramedullary nails, external fixation devices. Round wooden rod with external diameter of 35 mm, internal diameter of 25 mm, which was saw in the middle with two cuts directed at an angle of 45° to the rod axis to form the triangle fragment, was picked for femur model for the purpose of experiment. The stability of bone fragments fixation using plates with angle stability, pin- and nail-type external fixation devices and blocking intramedullary nails was assessed. To test the stability of the «bone-fixing device» complex, torsional test machine КМ-50-1 №66, power press П-10 №92, pull test machine Р-10 №1677 were used. Results. Compared to external fixation device, fixation using plates with angle stability was 6 times more stable at axial load and by 43.5% at lateral load. The stability of blocking intramedullary nail at axial load was higher compared to external fixation device. At rotary load, the stability of blocking intramedullary nail was 2 times lower compared to external fixation device. Conclusion. On a model of splintered double-lever femur fractures, fixation using plates with angle stability was the most stable fixation mode.

Uneventful delivery of two pregnancies in a woman with severe factor XII deficiency: case report and systematic review

2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Stamatios Petousis ◽  
George Karavas ◽  
Chrysoula Margioula-Siarkou ◽  
Themistoklis Dagklis ◽  
Paraskevi Karapavlidou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Case Series ◽  
Signs And Symptoms ◽  
Factor Xii ◽  
Case Presentation ◽  
Severe Deficiency ◽  
Pubmed Database ◽  
Increased Risk

Abstract Background Deficiency of factor XII (FXII) is widely considered to have a detrimental effect on pregnancy. Several reports underline the increased risk for antenatal complications with few published case reports of uncomplicated deliveries. The main objective of our article is to perform a systematic review to highlight pregnancies with severe deficiency of FXII that have been delivered uneventfully, along with presenting our relative case of a woman with severe deficiency of FXII. Materials and methods A systematic review was performed in the Pubmed database. Inclusion criteria were considered to be case reports and case series presenting delivery of uncomplicated pregnancies in women with severe FXII deficiency. Medical records of our patient were also reviewed in terms of signs and symptoms, laboratory and imaging examinations and neonatal outcomes. Results There were 62 abstracts derived while 44 were assessed for eligibility. There were finally three case reports of women with FXII deficiency delivering live newborns and one case series of 12 women with a final outcome of 19 deliveries. Regarding our case presentation, the woman with FXII levels <12%, after a neonatal death because of extreme prematurity (24 weeks + 4 days), was set in regular follow-up and treatment with bemiparin natriate, 3.5 mg/kg and acetylsalicylic acid, 100 mg/day. She finally managed to have her second pregnancy delivered at 38 weeks + 3 days, her third pregnancy ended up as a miscarriage and her fourth pregnancy was also delivered at 37 weeks + 4 days. Conclusion Despite the increased risk for antenatal complications, appropriate follow-up of pregnancies with severe FXII pregnancy may finally lead to an uneventful delivery.

scholarly journals Esophageal Adenocarcinoma with Extensive Metastasis to Unexpected Sites: A Case Report

2018 ◽  
Vol 11 (3) ◽  
pp. 742-750
Author(s):  
Vincent Louie Mendiola ◽  
Maurice Willis
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Morbidity Rate ◽  
Case Presentation ◽  
Mortality And Morbidity ◽  
New Finding ◽  
Hispanic Male ◽  
Metastasis Site ◽  
Very High ◽  
New Onset

Background: Esophageal cancer (EC) with unexpected metastasis (UM) to unusual sites have been increasingly reported. EC with metastasis in general has a very high mortality and morbidity rate, and those with UM to unusual sites present another specific field that needs to be further studied in order to understand and manage the presentation. An extensive systematic review was recently completed regarding this field which identified characteristics and findings concerning patients with EC with UM sites. Case Presentation: We report a 61 year old Hispanic male who had an EC, adenocarcinoma subtype, with UM to an extensive number of sites such as the soft tissue of the cheek, subcutaneous forehead and scalp with penetration of the calvarium, occipital bone, base of tongue, neck muscles, paraspinal and iliopsoas musculature and, more typically, to an adrenal gland followed by a questionable new-onset finding of subcutaneous shoulder and flank nodules not initially identified by imaging. Discussion/Conclusion: The case reports a patient who not only had EC with UM to unusual sites, but also to a considerable number. The patient correlated well in terms of clinical features identified by the systematic review of this particular field, but his case also showed a new finding, another unexpected metastasis site. This case also shows an example of why the type of imaging is important when dealing with UM sites. With this, we hope to further add to the data in this particular field and provide some opinion on this matter.

Cannabis-associated arteritis

VASA ◽  
2010 ◽  
Vol 39 (1) ◽  
pp. 43-53 ◽  
Author(s):  
Grotenhermen
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Case Series ◽  
Cardiovascular Effects ◽  
Causative Factor ◽  
Cannabis Use ◽  
Thromboangiitis Obliterans ◽  
Pathological Features ◽  
Scientific Support ◽  
Clinical And Pathological Features

Background: To investigate the hypothesis that cases of arteritis similar to thromboangiitis obliterans (TAO) and associated with the use of cannabis were caused by cannabis or THC (dronabinol), or that cannabis use is a co-factor of TAO. Patients and methods: A systematic review on case reports and the literature on so-called cannabis arteritis, TAO, and cardiovascular effects of cannabinoids was conducted. Results: Fifteen reports with 57 cases of an arteritis associated with the use of cannabis and two additional case series of TAO, in which some patients also used cannabis, were identified. Clinical and pathological features of cannabis-associated arteritis do not differ from TAO and the major risk factor of TAO, tobacco use, was present in most, if not in all of these cases. The proposed pathophysiological mechanisms for the development of an arteritis by cannabis use are not substantiated. Conclusions: The hypothesis of cannabis being a causative factor or co-factor of TAO or an arteritis similar to TAO is not supported by the available evidence. The use of the term “cannabis arteritis” should be avoided until or unless more convincing scientific support is forthcoming.

Dietary Vitamin and Stability of Oral Anticoagulation: Proposal of a Diet with Constant Vitamin K1 Content

1997 ◽  
Vol 77 (03) ◽  
pp. 504-509 ◽  
Author(s):  
Sarah L Booth ◽  
Jacqueline M Charnley ◽  
James A Sadowski ◽  
Edward Saltzman ◽  
Edwin G Bovill ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Vitamin K ◽  
High Performance ◽  
Case Reports ◽  
Food Composition ◽  
Dietary Guidelines ◽  
Dietary Vitamin ◽  
Vitamin K1 ◽  
The Stability ◽  
The Impact

SummaryCase reports cited in Medline or Biological Abstracts (1966-1996) were reviewed to evaluate the impact of vitamin K1 dietary intake on the stability of anticoagulant control in patients using coumarin derivatives. Reported nutrient-drug interactions cannot always be explained by the vitamin K1 content of the food items. However, metabolic data indicate that a consistent dietary intake of vitamin K is important to attain a daily equilibrium in vitamin K status. We report a diet that provides a stable intake of vitamin K1, equivalent to the current U.S. Recommended Dietary Allowance, using food composition data derived from high-performance liquid chromatography. Inconsistencies in the published literature indicate that prospective clinical studies should be undertaken to clarify the putative dietary vitamin K1-coumarin interaction. The dietary guidelines reported here may be used in such studies.

Capecitabine Induced Hand-Foot Syndrome: A Systematic Review of Case Reports

2019 ◽  
Author(s):  
Elif ARAS ◽  
Kamer Tecen YÜCEL ◽  
Aygin Bayraktar EKİNCİOĞLU ◽  
İbrahim GÜLLÜ
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Hand Foot Syndrome
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