scholarly journals Severity-dependent variations of the neutrophil to lymphocyte ratio (NLR) in peripheral vestibular vertigo

2021 ◽  
Vol 57 (1) ◽  
Author(s):  
Andi Kurnia Bintang ◽  
Eva Iin Magasingan
Keyword(s):  
Inflammatory Marker ◽  
Cost Effective ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Neutrophil To Lymphocyte Ratio ◽  
University Teaching ◽  
Cross Sectional ◽  
Lymphocyte Ratio ◽  
Significant Difference ◽  
Vestibular Vertigo

Abstract Background Peripheral vestibular vertigo is a common cause of vertigo especially in the elderly. The neutrophil to lymphocyte ratio (NLR) is a rapid and cost-effective inflammatory marker that has been assessed previously in peripheral vestibular disorders. However, its relation to the severity of peripheral vertigo has not been previously investigated. The aim of this study is to assess the levels of NLR in peripheral vestibular vertigo of various severity categories. This was a cross-sectional study at the Wahidin Sudirohusodo Hospital and Hasanuddin University Teaching Hospital in Makassar. The NLR was measured among subjects with periphel vestibular vertigo with severity categorised using the Dizziness Handicap Inventory (DHI) questionnaire. Results A total of 39 participants with peripheral vestibular vertigo were recruited. A statistically significant difference was found (p = 0.002, Kruskal–Wallis ANOVA) between the mean NLR for the mild, moderate, and severe DHI categories were 2.47 ± 1.66, 2.64 ± 0.96, and 5.15 ± 2.59 respectively. Conclusion A significant difference in the NLR was found between the three different vertigo severity groups, wherein NLR values rise with increase in vertigo severity. This warrants further exploration on the role of inflammatory biomarkers in vertigo pathophysiology and clinical assessment.

scholarly journals Predictive value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Patients with Vaginitis

2020 ◽  
Vol 37 (1) ◽  
Author(s):  
Eren Pek ◽  
Fatma Beyazit ◽  
Nilay Sen Korkmaz
Keyword(s):  
Bacterial Vaginosis ◽  
Predictive Value ◽  
Inflammatory Marker ◽  
Diagnostic Value ◽  
Neutrophil To Lymphocyte Ratio ◽  
Platelet To Lymphocyte Ratio ◽  
Cross Sectional ◽  
Distribution Width ◽  
Lymphocyte Ratio ◽  
Significant Difference

Objectives: This study was conducted to evaluate the diagnostic value of platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in vaginitis patients. Methods: This cross-sectional retrospective study was performed in Afyon Dinar State Hospital between July 2016 to August 2017. A total of 64 bacterial vaginosis (BV) patients, 66 vulvovaginal candidiasis (VVC) patients and 65 age-matched control subjects were enrolled. NLR, PLR, mean platelet volume (MPV), red cell distribution width (RDW) and other conventional inflammatory marker values were recorded for all patients before and after treatment. Results: In the BV group, NLR values were found to be elevated compared to VVC and healthy controls [2.9 (1.2-14.7), 2.1 (1.1-11.7) and 2.1 (0.8-7.0), respectively] (p=0.008). Although not found to be statistically significant, the median NLR levels of BV patients decreased from 2.9 (1.2-14.7) to 2.4 (1.2-7.0) after treatment. PLR levels did not show a statistically significant difference between the three groups (p=0.970). The cut-off value of the NLR for BV was 2.19, with 67.2% sensitivity and 63.8% specificity. Conclusions: The present study demonstrated that NLR levels are elevated in bacterial vaginosis and NLR levels can be used as a reflection of systemic inflammatory response in vaginosis patients. doi: https://doi.org/10.12669/pjms.37.1.2774 How to cite this:Pek E, Beyazit F, Korkmaz NS. Predictive value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Patients with Vaginitis. Pak J Med Sci. 2021;37(1):250-255. doi: https://doi.org/10.12669/pjms.37.1.2774 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals ANGKA BANDING NETROFIL/LIMFOSIT DI POPULASI DEWASA MUDA

2018 ◽  
Vol 22 (2) ◽  
pp. 105
Author(s):  
Arie Yanti ◽  
Uleng Bahrun ◽  
Mansyur Arif
Keyword(s):  
Adult Population ◽  
Reference Value ◽  
Severe Infection ◽  
Cost Effective ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical Checkup ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Significant Difference

Previous studies have shown that neutrophil/lymphocyte ratio in bacteremia is higher than nonbacteremia, therefore it could beused as a marker to distinguish both conditions in patients with sepsis .Another study on oncology patients in ICU showed a correlationbetween the severity of clinical course and the increase of neutrophil/lymphocyte ratio. In physiological condition, neutrophil/lymphocyteratio <5, while in pathological conditions (severe infection or systemic inflammation) neutrophil/lymphocyte ratio increases >6.Neutrophil/lymphocyte ratio is a sensitive, fast, cost effective and applicable laboratory test for routine use, therefore this test result canbe used as the parameter to assess clinical condition of patients. However, a reference value of neutrophil/lymphocyte ratio has neverbeen defined, especially in Makassar City, South Sulawesi Province. The aim of this study was to know the neutrophil/lymphocyte ratioin a healthy young adult population. A cross sectional study was conducted from March to April 2014, involving residents (specialisticcandidates in Medical Faculty, Hasanuddin University, who underwwent medical checkup and voluntarily joined this study. Samplesconsisted of 198 persons who fulfilled the inclusion criteria with an age range between 24-40 years old, comprising 84 males (42.42%)and 114 females (57.58%). The neutrophil/lymphocyte ratio for all samples was 1.95 (1.15-4.74). Mann Whitney test showed thatthere was no significant difference of neutrophil/lymphocyte ratio between males and females, 1.88 (1.25-4.74) vs 1.95 (1.15-4.12),p=0.65 and neither between the age group 21-30 years old and 31-40 years old, 1.95 (1.21-4.74) vs 1.94 (1.15-4.09), p=0.82.

scholarly journals The Correlation Between Asthma Severity and Neutrophil to Lymphocyte Ratio

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Meena Abdul-Sattar Darwesh ◽  
Ibtihal Shukri Abd Alhaleem ◽  
Muhammed Waheeb Salman Al-Obaidy
Keyword(s):  
Clinical Symptoms ◽  
Asthma Severity ◽  
Cross Sectional Study ◽  
Neutrophil To Lymphocyte Ratio ◽  
Healthy Controls ◽  
Cross Sectional ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Asthmatic Patients ◽  
Significant Difference

Background—The prognosis is essential in management and follows up of asthmatic patients. Neutrophil to lymphocyte ratio is considered as the common prognostic marker for many diseases especially the asthma. Aim of study—To assess the relationship between asthma severity and neutrophil to lymphocyte ratio in comparison to healthy controls. Patients and methods—This study is a cross sectional study conducted in Respiratory Consultancy Clinic in Baghdad Teaching Hospital in Medical City during the period from 1st of October, 2018 to 31st of March, 2019 on sample of 50 asthmatic patients and 50 healthy controls. The diagnosis of asthma was confirmed by the supervisor through clinical symptoms, signs, spirometery with reversibility test (according to GINA guideline.). Results—A highly significant difference was observed between asthmatic cases and controls regarding age (p<0.001). A significant association was observed between obesity and asthmatic cases (p=0.001). There was a highly significant association between high neutrophil/lymphocyte ratio and asthmatic cases (p<0.001). The neutrophil/lymphocyte ratio was significantly increased with advanced age, females, severe and uncontrolled asthma. Conclusions—The neutrophil to lymphocyte ratio is useful biomarker in assessment of asthma severity.

scholarly journals A Cross-Sectional Study of Neutrophil-to-Lymphocyte Ratio in Diagnosing Acute Appendicitis in Hospital Melaka

2019 ◽  
Vol 26 (6) ◽  
pp. 55-66
Author(s):  
Khairol Ashraf Ahmad ◽  
◽  
Noorharisman Ideris ◽  
Syed Hassan Syed Abd Aziz ◽  
◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Cross Sectional Study ◽  
Neutrophil To Lymphocyte Ratio ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lymphocyte Ratio

The Evaluation of the Awareness, Attitude and Practice of the Elderly Toward Self-Medication: A Cross-Sectional Study

Drug Research ◽  
2018 ◽  
Vol 68 (08) ◽  
pp. 475-480
Author(s):  
Mohammad Heidari ◽  
Mansureh Borujeni ◽  
Mansour Ghafourifard ◽  
Rahim Sheikhi
Keyword(s):  
Rural Areas ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Average Score ◽  
Self Medication ◽  
Cross Sectional ◽  
Attitudes And Practices ◽  
Age Related ◽  
Significant Difference ◽  
Urban And Rural Areas

Abstract Introduction The prevalence of various diseases in the elderly has increased the use of drugs, which is coupled with age-related physiological changes and places the elderly at risk for multiple side effects. The present study aimed to determine awareness, attitudes and practices of elderly towards self-medication. Materials and Methods The sample included 300 participants over 60 years under any of the health centers in urban and rural areas of Abadeh city, who were selected based on stratified random sampling method. In order to collect data, the questionnaire including demographic information, awareness, attitude and performance of the elderly and the checklist of drug intractable consumption. Results Based on the results, 76% of the elderly reported drug consumption. Regarding lifestyle, the average score of the elderly’s awareness for the elderly who lived with and without families were 78.6±14.2 and 69.2±13.6, respectively. In other words, a significant difference was observed between these two groups. In addition, there was a significant between the elderly’s performance score with and without family members about the self-medication (p=0.001). Conclusion Considering the increase in self-medication among the elderly, adherence to prescription criteria for drug among this age group is recommended. Finally, designing and implementing various educational programs in health education center is necessary for the elderly and their families for the purpose of improving awareness and practice.

scholarly journals Associations between the Neutrophil-to-Lymphocyte Ratio and Diabetic Complications in Adults with Diabetes: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Heng Wan ◽  
Yuying Wang ◽  
Sijie Fang ◽  
Yi Chen ◽  
Wen Zhang ◽  
...  
Keyword(s):  
Diabetic Complications ◽  
Large Population ◽  
Cross Sectional Study ◽  
Cerebrovascular Diseases ◽  
Neutrophil To Lymphocyte Ratio ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Lymphocyte Ratio ◽  
Urine Albumin ◽  
Laboratory Index

Objective. The neutrophil-to-lymphocyte ratio (NLR) is an inexpensive and easily measurable laboratory index indicating systemic inflammation, while the application of many other inflammatory markers has been limited in daily clinical practice. However, large population studies about investigating the associations of the NLR level with diabetic complications including cardiovascular and cerebrovascular diseases (CVD), diabetic kidney disease (DKD), and diabetic retinopathy (DR) in the same population were limited. The aim of our study is to evaluate the associations between the NLR level and the prevalence of CVD, DKD, and DR in adults with diabetes simultaneously. Methods. A cross-sectional survey of 4,813 diabetic adults was conducted in seven communities in China. Persons underwent several medical examinations, including the measurement of anthropometric factors, blood pressure, routinely analyzed leukocyte characteristics, glucose, lipid profiles, urine albumin/creatinine ratio, and fundus photographs. Results. Compared with the first quartile of the NLR level, the odds of having CVD was significantly increased by 21% for participants in the highest quartile (OR 1.21; 95% CI 1.00, 1.47) (P for trend<0.05). Similarly, the prevalence of DKD among participants in the highest quartile of the NLR level was significantly increased by 150% (OR 2.50; 95% CI 1.95, 3.19) (P for trend<0.05). However, no association was found between the NLR level and the prevalence of DR (P for trend>0.05). These associations were all fully adjusted. Conclusions. A higher NLR level was associated with an increased prevalence of CVD and DKD, other than DR, in diabetic adults.

scholarly journals Malnutrition in free-living elderly in rural south India: prevalence and risk factors

2009 ◽  
Vol 13 (9) ◽  
pp. 1328-1332 ◽  
Author(s):  
Aditya Vedantam ◽  
Vijay Subramanian ◽  
Nicholas Vijay Rao ◽  
KR John
Keyword(s):  
Tamil Nadu ◽  
South India ◽  
Nutritional Assessment ◽  
Mini Nutritional Assessment ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Free Living ◽  
Cross Sectional ◽  
Significant Difference

AbstractObjectiveTo estimate the prevalence of malnutrition among free-living elderly in a rural population of south India.DesignCross-sectional study. Nutritional status was assessed using the Mini Nutritional Assessment (MNA) questionnaire, which is an eighteen-item nutritional screening instrument used in the elderly.SettingKaniyambadi block, a rural development block in the state of Tamil Nadu, south India.SubjectsCommunity-dwelling elderly (aged 60 years and above).ResultsAs evaluated by the MNA, 14 % of the 227 subjects were malnourished and 49 % were at risk of malnourishment. No significant difference was found between men and women. The majority of the elderly were living with their children, had no income and consumed three meals per day. Older age (P < 0·001), decreased food intake (P < 0·001) and consuming fewer meals (P < 0·001) were independently associated with lower MNA scores.ConclusionsMore than 60 % of the subjects had low MNA scores (<23·5) indicating that deficient protein–energy intake is common among rural elderly of south India and requires more attention.

scholarly journals Estado mental dos idosos em hemodiálise no serviço de nefrologia

2019 ◽  
Vol 13 (5) ◽  
pp. 1192
Author(s):  
Alexandre Lins Werneck ◽  
Rita de Cássia Helu Mendonça Ribeiro ◽  
Claudia Beranardi Cesarino ◽  
Daniele Alcalá Pompeo ◽  
Daniela Comelis Bertolin ◽  
...  
Keyword(s):  
Mental State ◽  
Cognitive Aging ◽  
Cognitive Deficit ◽  
Treatment Time ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Clinical Aspects ◽  
Status Change ◽  
Cross Sectional ◽  
Significant Difference

RESUMO Objetivo: caracterizar os aspectos sociodemográficos, econômicos e clínicos e analisar o estado mental dos idosos em hemodiálise. Método: trata-se de um estudo quantitativo, analítico, descritivo, transversal. Compôs-se a amostra por 94 pacientes idosos, com 65 anos ou mais, em tratamento no serviço de hemodiálise. Realizou-se o estudo por meio de instrumento de caracterização dos sujeitos e questionário miniexame do estado mental. Testou-se, na análise estatística, a diferença entre o número de indivíduos com e sem alteração do estado mental por meio de teste binomial, utilizado o critério de Akaike (AIC) e a regressão logística. Apresentaram-se os resultados em forma de tabelas e figuras. Resultados: ressalta-se que destes, 78% apresentaram deficit cognitivo, demonstrando diferença significativa (p<0.01). Apresentaram-se as variáveis “idade” e “origem” (urbana ou rural) relevância com a presença e a ausência de deficit cognitivo. Verificou-se que a idade apresentou aumento de 62% nas chances de deficit para cada um ano de idade do paciente. Conclusão: concluiu-se que a maioria dos idosos apresentou deficit cognitivo independente do tempo de tratamento, o que pode ser um indício de efeito momentâneo da hemodiálise nos pacientes. Descritores: Geriatria; Envelhecimento Cognitivo; Hemodiálise; Cognição; Doença Renal Crônica; Enfermagem.ABSTRACT Objective: to characterize sociodemographic, economic and clinical aspects and to analyze the mental state of the elderly on hemodialysis. Method: this is a quantitative, analytical, descriptive, cross-sectional study. The sample was composed of 94 elderly patients, aged 65 years or more, undergoing treatment at the hemodialysis service. The study was carried out by means of an instrument of characterization of the subjects and miniexame questionnaire of the mental state. In the statistical analysis, the difference between the number of individuals with and without mental status change was tested using a binomial test, using the Akaike criterion (AIC) and logistic regression. Results were presented in the form of tables and figures. Results: 78% presented cognitive deficits, showing a significant difference (p <0.01). We presented the variables "age" and "origin" (urban or rural) relevance with the presence and absence of cognitive deficit. It was verified that the age presented a 62% increase in the chances of deficit for each one year of age of the patient. Conclusion: it was concluded that the majority of the elderly presented cognitive deficit independent of treatment time, which may be an indication of momentary effect of hemodialysis in patients. Descriptors: Geriatrics; Cognitive Aging; Hemodialysis; Cognition; Chronic Kidney Disease; Nursing.RESUMEN Objetivo: caracterizar los aspectos sociodemográficos, económicos y clínicos y analizar el estado mental de los ancianos en hemodiálisis. Método: se trata de un estudio cuantitativo, analítico, descriptivo, transversal. Se compuso la muestra por 94 pacientes ancianos, con 65 años o más, en tratamiento en el servicio de hemodiálisis. Se realizó el estudio por medio de instrumento de caracterización de los sujetos y cuestionario mini examen del estado mental. En el análisis estadístico se probó la diferencia entre el número de individuos con y sin alteración del estado mental por medio de la prueba binomial, utilizado el criterio de Akaike (AIC) y la regresión logística. Se presentaron los resultados en forma de tablas y figuras. Resultados: se resalta que de éstos, 78% presentaron déficit cognitivo, demostrando diferencia significativa (p <0.01). Se presentaron las variables "edad" y "origen" (urbana o rural) relevancia con la presencia y la ausencia de déficit cognitivo. Se verificó que la edad presentó un aumento de 62% en las posibilidades de déficit por cada año de edad del paciente. Conclusión: se concluyó que la mayoría de los ancianos presentó déficit cognitivo independiente del tiempo de tratamiento, lo que puede ser un indicio de efecto momentáneo de la hemodiálisis en los pacientes. Descriptores: Geriatría; Envejecimiento Cognitivo; Diálisis Renal; Cognición; Insuficiência Renal Crônica; Enfermería.

scholarly journals Predictors of nursing workload in elderly patients admitted to intensive care units

2008 ◽  
Vol 16 (2) ◽  
pp. 218-223 ◽  
Author(s):  
Cleber Ricardo de Sousa ◽  
Leilane Andrade Gonçalves ◽  
Maria Cecília Toffoleto ◽  
Karine Leão ◽  
Kátia Grillo Padilha
Keyword(s):  
Intensive Care ◽  
Elderly Patients ◽  
The Elderly ◽  
Simplified Acute Physiology Score ◽  
Cross Sectional Study ◽  
Nursing Workload ◽  
Cross Sectional ◽  
Significant Difference ◽  
Surgical Icu ◽  
Independent Risk Factors

The age of patients is a controversial issue in admission to intensive care unit (ICU). The aim of this study was to compare severity and nursing workload of elderly patients with 60-69, 70-79, and e"80 years of age and to identify predictors of nursing workload in elderly patients. A cross sectional study was performed with a sample of 71 elderly patients admitted to three ICU in the city of Sao Paulo, Brazil from October to November 2004. Data were prospectively collected using Nursing Activities Score (NAS) and Simplified Acute Physiology Score II (SAPS II). There was no significant difference in nursing workload among the elderly patients age subgroups (p=0.84). Multiple regression analysis indicated that the independent risk factors of high nursing workload were severity, age e"70 years, and to be a surgical ICU patient. Age as an isolated factor should not be discriminative for elderly patients admission to ICU.

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