General Paresis Complicating Huntington's Chorea

1958 ◽  
Vol 104 (437) ◽  
pp. 1203-1204 ◽  
Author(s):  
H. Merskey

That chorea may sometimes occur as a result of cerebral syphilis has been accepted for some years (Kinnier Wilson 1940) and it has often previously been reported in association with G.P.I. The literature on the topic is dealt with by Lowrey and Smith (1918), Stone and Falstein (1938) and Weickhardt (1945). In all the reports however I can find only three previous instances where clinical and serological evidence of G.P.I. in a patient was associated with a family history and clinical syndrome of Huntington's chorea. These cases were reported by Pagliano and Aviennos (1922), Urechia and Rusdea (1922) and Stone and Falstein (1938) and the case here described appears to be only the fourth similar example to be reported. It has a practical as well as an academic interest since the differential diagnosis of the early stages of Huntington's chorea from those of G.P.I. is still sometimes necessary.

2009 ◽  
Vol 2009 ◽  
pp. 1-2 ◽  
Author(s):  
Caner Sahin

Nasolabial cyst is a rare nonodontogenics, soft-tissue cyst occurring in the sublabial area and anterior maxillary region. The patient usually presents with a slowly enlarging asymptomatic swelling. They are usually diagnosed in early stages because of cosmetic problems. In our paper we report anasolabial cystof a 53-year-old man and discuss the diagnosis, differential diagnosis, and treatment in the light of the literature.


2019 ◽  
Vol 81 (1) ◽  
pp. 9
Author(s):  
O. Yu. Olisova ◽  
E. V. Grekova ◽  
V. A. Varshavsky ◽  
L. G. Gorenkova ◽  
E. A. Alekseeva ◽  
...  

2021 ◽  
Vol 2 (2) ◽  
pp. 80-87
Author(s):  
Z A. Goncharova ◽  
Y. Y. Pogrebnova

Objective: to describe the clinical and epidemiological features of idiopathic inflammatory demyelinating diseases and to determine the factors influencing their course. Materials and methods: the study included 803 patients with idiopathic inflammatory demyelinating diseases using patient questionnaires and scales, laboratory and instrumental research methods. Statistical processing of the results was carried out using a point biserial coefficient and programs for analyzing large data arrays and machine learning. Results: a dynamic increase in the prevalence of some forms of idiopathic inflammatory demyelinating diseases was revealed, the difficulties of differential diagnosis of rare forms of demyelination and the need to create a unified version of their classification are reflected. In the studied population, the effectiveness of liquorological examination in the diagnosis of multiple sclerosis in the early stages of the disease was shown. It has been shown that the likelihood of developing highly active multiple sclerosis is influenced by both a genetic factor and concomitant inflammatory, allergic and autoimmune diseases, surgical interventions, dietary habits, childhood infections, and a history of pregnancy. Conclusions: given the complexity of the differential diagnosis of idiopathic inflammatory demyelinating diseases and the appointment of modifying therapy in multiple sclerosis in the early stages, it is necessary to create a combined classification and maintain a common register.


Author(s):  
N. Stander ◽  
R. M. Kirberger

Complications related to extraluminal migration of ingested kebab (sosatie) sticks are infrequently diagnosed in small animals. A total of 8 cases diagnosed with extragastric migration of ingested kebab sticks were retrospectively evaluated. No significant breed or sex predilection was found but there was a tendency for animals to present at a younger age (less than 3 years). Clinical signs (of variable duration) were non-specific and included haemoptysis, abdominal pain, regurgitation, subcutaneous abscessation and chronic draining sinus tracts, making a clinical diagnosis difficult. Ultrasonography proved invaluable in facilitating the diagnosis of kebab stick migration in 6 of the cases and computed tomography unexpectedly identified a kebab stick that had migrated into the thorax in 1 patient. Survey radiography was generally found to be insensitive in identifying the kebab sticks. The aim of this article is to alert veterinarians to a clinical syndrome that may not be considered a differential diagnosis in patients with non-specific inflammatory disease of the thorax, abdomen or pelvic regions and to illustrate the usefulness of the various diagnostic imaging modalities in facilitating a diagnosis of kebab stick ingestion and its possible secondary complications.


2021 ◽  
Vol 14 (6) ◽  
pp. e242227
Author(s):  
Catarina Cordeiro ◽  
Paula Garcia ◽  
Dalila Coelho ◽  
Mónica Oliva

Congenital cataract can be caused by several systemic diseases and differential diagnosis should be done between infections, genetic or metabolic diseases. We present a case of a 12-month-old girl with bilateral nuclear cataracts that was referred for investigation. Since she did not present a family history of congenital cataracts or metabolic diseases, and her physical examination was normal, a systemic evaluation was performed. Biochemical studies disclosed abnormal galactose metabolism signs. The diagnosis of galactokinase (GALK1) deficiency was considered and the study of the GALK1 gene allowed identifying a pathogenic genetic variant and a predictably pathogenic missense mutation, previously not described. Dietary measures were imposed with a good evolution.


Author(s):  
Н. Воротынцева ◽  
N. Vorotynceva ◽  
И. Мошуров ◽  
I. Moshurov ◽  
М. Ганзя ◽  
...  

Background: With the growth in the equipment clinics with modern diagnostic equipment is increasing the detectability of male breast pathology. In this connection there is a need to determine X-ray characteristics of some forms of the male breast pathology especially breast cancer, because in Russia it stills a problem of detecting male breast cancer at early stages. Purpose: To determine the diagnostic capabilities of chest CT to detect various pathologies of the male breast and to identify the statistically significant radiological symptoms for the differential diagnosis of pseudogynecomastia, gynecomastia and breast cancer. Material and methods: 150 chest CT of men who were screened and treated for the various diseases in the Voronezh Regional Clinical Diagnostic Center and Kursk Regional Clinical Hospital in 2013–2015. X-ray examinations (13 chest CT, 4 PET-CT and 16 mammography) of 31 male patients with breast cancer who were surgically treated at the Voronezh Regional Oncology Hospital in 2010–2016 are presented. Results: The obtained data on the prevalence of pseudogynecomastia and gynecomastia in men who have no presenting complaints about changes in breast. Determined the forms of gynecomastia in this group of patients. Identified radiographic signs that allow a differential diagnosis between gynecomastia and breast cancer. Conclusions: 1. Gynecomastia is a common pathology of the male breast diagnosed by chest CT, and was diagnosed in 68.7 % of patients, who have no presenting complaints about changes in breast. In 96.1 % of cases, gynecomastia had a dendritic form. Diffuse glandular and nodular were rare forms of the disease and were respectively 2.9 % and 1 % of all cases of this disease. 2. Statistically significant signs of malignant character of breast masses in men were: a) the connection of the tumor with skin, areola or nipple in the form of «track» to them, thickening of the skin, «pulling» of the skin or nipple to neoplasm or their immediate invasion by tumor; b) tumor invasion into the pectoralis major muscle; c) presence of microcalcifications in neoplasm; d) presence of pathologically altered axillary lymph nodes. The determination of these radiological symptoms require immediate consultation of an oncologist. 3. Statistically significant signs of the benign character of breast masses in men were: a) bilateral lesion and the symmetry of the changes in the breasts; b) adipose tissue inclusions in breast masses. When detection gynecomastia it needs the consultation of urologist, endocrinologist, oncologist. 4. Awareness of physicians and radiologists on the possibility of developing breast cancer in men and the knowledge of the symptoms of this disease is crucial to detect male breast cancer at early stages and, as a consequence, more successful treatment and a favorable prognosis.


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