Cancer-related self-efficacy in African American prostate cancer patients compared to whites

5067 Background: African American (AA) men are nearly twice as likely as white (W) men to be diagnosed with prostate cancer. Cancer-related self-efficacy (i.e., confidence in one's ability to manage cancer) has been associated with better physical and psychosocial functioning, but little is known about self-efficacy in African American prostate cancer patients. This study compared AA and W ratings of cancer-related self-efficacy for 308 prostate cancer patients (M age = 66.13, SD = 8.48; 9% AA) who participated in a group therapy intervention. Method: Independent groups t-tests were used to determine whether there were significant differences at baseline in mean scores for each group on the Stanford Self-Efficacy Scale (SSE), which asks respondents to rate their confidence in the ability to cope with cancer on a 0–100 scale, with 0 indicating no confidence. SSE subscales measure self-efficacy in the ability to: a) communicate with family, friends, and healtcare providers; b) focus and relax; and c) cope with the possibility of dying. Results: A significant difference was observed on SSE total scores (AA mean = 60.39 vs. W mean = 72.70; t = 3.30; p = 0.003). There were also significant differences on the Focus/Relax (AA mean = 68.90 vs. W mean = 77.64; t = 2.04; p = 0.011) and Cope with Dying (AA mean = 49.72 vs. W mean = 70.12; t = 4.85; p = 0.001) subscales, with a trend towards significance on the Ability to Communicate (AA mean = 62.55 vs. W mean = 70.76; t = 3.36; p = 0.095). Conclusions: Results suggest that, compared to W men, AA men have less confidence in their ability to cope with prostate cancer following diagnosis. AA men report the least confidence in their ability to cope with the possibility of death as a result of cancer, and they also report less confidence in their ability to focus and relax. They may also have greater difficulty discussing their cancer with family, friends, and healthcare personnel. As cancer-related self-efficacy has been linked to symptom-related and psychological adjustment, interventions targeting self-efficacy in AA prostate cancer patients are needed that are tailored to their unique needs. No significant financial relationships to disclose.

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Dysregulated gene expression predicts tumor aggressiveness in African-American prostate cancer patients

Scientific Reports ◽

10.1038/s41598-018-34637-8 ◽

2018 ◽

Vol 8 (1) ◽

Cited By ~ 6

Author(s):

Hamdy E. A. Ali ◽

Pei-Yau Lung ◽

Andrew B. Sholl ◽

Shaimaa A. Gad ◽

Juan J. Bustamante ◽

...

Keyword(s):

Gene Expression ◽

Prostate Cancer ◽

African American ◽

Cancer Patients ◽

Tumor Aggressiveness

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PD40-07 ADDRESSING HEALTH LITERACY IMPROVES SHARED DECISION MAKING IN UNDERSERVED AFRICAN AMERICAN PROSTATE CANCER PATIENTS

The Journal of Urology ◽

10.1097/ju.0000000000000920.07 ◽

2020 ◽

Vol 203 ◽

pp. e817-e818

Author(s):

Kerry Kilbridge ◽

William Martin-Doyle* ◽

Christopher Filson ◽

Quoc-Dien Trinh ◽

Sierra Williams ◽

...

Keyword(s):

Prostate Cancer ◽

Decision Making ◽

African American ◽

Health Literacy ◽

Cancer Patients ◽

Shared Decision Making ◽

Shared Decision

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A Pilot Study of a Culturally Grounded Breastfeeding Intervention for Pregnant, Low-Income African American Women

Journal of Human Lactation ◽

10.1177/0890334418775050 ◽

2018 ◽

Vol 34 (3) ◽

pp. 478-484

Author(s):

Rebecca Reno

Keyword(s):

African American ◽

Pilot Study ◽

African American Women ◽

Health Equity ◽

Low Income ◽

Self Efficacy ◽

Short Form ◽

Assessment Process ◽

American Women ◽

Significant Difference

Background: Increasing breastfeeding rates among low-income African American women may work toward the achievement of health equity. The dynamic breastfeeding assessment process (D-BAP) is a community-grounded, equity-focused intervention designed to increase prenatal breastfeeding self-efficacy. Research aim: The aims of the pilot study were (a) to determine the effect of the D-BAP on breastfeeding self-efficacy among pregnant, low-income African American women, (b) to examine the findings among women with no previous breastfeeding experience, and (c) to compare the findings between women with prior breastfeeding experience and those without it. Methods: A pre/post, paired-samples design was utilized. Convenience sampling was used to recruit pregnant, low-income African American women ( N = 25). Participants completed the Breastfeeding Self-Efficacy Scale–Short Form prior to and following the D-BAP. Results: The Wilcoxon signed rank test indicated that participation in the D-BAP had a statistically significant influence on breastfeeding self-efficacy ( z = −2.01, p = .04). Among a subsample of participants with no previous breastfeeding experience ( n = 12), completion of the D-BAP resulted in a statistically significant increase in breastfeeding self-efficacy ( z = −2.36, p = .02). There was no statistically significant difference between those with prior breastfeeding experience and those without it. Conclusion: Breastfeeding among low-income African American women is a health equity issue for which culturally responsive, effective breastfeeding interventions are needed. This research demonstrates an association between completion of the D-BAP and an increase in prenatal breastfeeding self-efficacy.

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Radiation Proctitis: The Potential Role of Hyaluronic Acid in the Prevention and Restoration of Any Damage to the Rectal Mucosa among Prostate Cancer Patients Submitted to Curative External Beam Radiotherapy

Gastroenterology Insights ◽

10.3390/gastroent12040043 ◽

2021 ◽

Vol 12 (4) ◽

pp. 446-455

Author(s):

Gianluca Ferini ◽

Antonella Tripoli ◽

Vincenza Umina ◽

Giuseppina Rita Borzì ◽

Valentina Anna Marchese ◽

...

Keyword(s):

Prostate Cancer ◽

Hyaluronic Acid ◽

Cancer Patients ◽

Radiation Proctitis ◽

Dose Fractionation ◽

Control Group ◽

Consecutive Series ◽

Median Dose ◽

Significant Difference ◽

Experimental Group

Aim: To evaluate if hyaluronic acid reduces proctitis episodes with respect to corticosteroids in prostate cancer patients submitted to radical or adjuvant radiotherapy. Methods: A consecutive series of eligible patients received hyaluronic acid enemas as supportive care (experimental group, from January 2013 to June 2015). A historical group (control group), treated from October 2011 to December 2012, received beclomethasone dipropionate suppositories. We registered each patient’s data regarding acute and chronic proctitis. All patients were treated with static-intensity-modulated radiotherapy coupled to a daily set-up verification with orthogonal anterior–posterior/lateral X-ray pairs. Results: A total of 269 patients, 175 in the experimental group and 94 in the control group, was evaluated; 2 Gy/day (up to a total median dose of 80 Gy) and 2.7 Gy/day (up to a total median dose of 67.5 Gy) fractionation schemes were used for 216 and 53 patients, respectively. All patients had a good tolerance to radiotherapy, reporting no G3 or greater proctitis. No significant difference was reported concerning the total rate of proctitis between the two groups but only with respect to its grade: a higher G2 rate within the control group. There was no correlation between daily dose fractionation and toxicity grade. Conclusions: Hyaluronic acid enemas might be effective in reducing the severity of radiation proctitis.

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Characteristics and Oncological Outcome of Clinical T3a Prostate Cancer Patients Undergoing Radical Prostatectomy in the Multi-Parametric MRI Era

10.21203/rs.3.rs-116649/v1 ◽

2020 ◽

Author(s):

Kasumi Yoshitomi ◽

Shinya Yamamoto ◽

Tatsuya Yamamoto ◽

Eri Fukagawa ◽

Kosuke Hamada ◽

...

Keyword(s):

Prostate Cancer ◽

Survival Rate ◽

Radical Prostatectomy ◽

Cancer Patients ◽

Digital Rectal Examination ◽

Oncological Outcome ◽

Risk Groups ◽

Free Survival ◽

Significant Difference ◽

Preoperative Factors

Abstract We aimed to reveal the association between the method of diagnosis (multi-parametric magnetic resonance imaging [mpMRI] and digital rectal examination [DRE]) and oncological outcomes of patients with clinical T3a (cT3a) prostate cancer after radical prostatectomy (RP) and stratify them according to oncological risk. We included 132 cT3a prostate cancer patients who underwent RP between 2008 and 2018. The biochemical recurrence (BCR)-free survival rate was evaluated according to the method of diagnosis (mpMRI alone; mpMRI group vs. DRE [with or without mpMRI]; DRE group). Several preoperative factors were evaluated in the multivariate analysis. Patients were divided into risk groups by our prediction model. The mpMRI group had significantly longer BCR-free survival than the DRE group (p<0.0001). The method of diagnosis (hazard ratio [HR]=2.69; 95% confidence interval [CI] 1.45-5.06; p=0.0017) and % positive cores (HR=4.36; 95% CI 1.14-16.5; p=0.031) were independent prognostic factors. Patients were divided into three risk groups based on these factors. There was a significant difference in BCR-free survival rate among the groups (p=0.0002).The method of diagnosis of cT3a prostate cancer was associated with BCR-free survival, and we categorized patients into risk groups. These assessments were attributable to the appropriate therapeutic strategy for patients with cT3a prostate cancer.

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