An oncogenetics consultation dedicated to children suffering from cancer.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e20006-e20006
Author(s):  
Véronique Mari ◽  
Marie Amelie Met Domestici ◽  
Christine Soler ◽  
Anne Deville ◽  
Nicolas Sirvent ◽  
...  

e20006 Background: When a child suffers from a cancer, parents worry about a probable hereditary cause. If a cancer occurs in the context of a genetic mutation, this can worsen the situation and make it more complicated. On the other hand, when the hereditary cause is rejected, the reinsurance for the family is clear. Methods: A partnership has been set between the Oncogenetics department in Centre Antoine Lacassagne Hospital in Nice and the Archet hospital in Nice (CHU) who takes in charge the children suffering from a cancer. Fifty little patients are seen every year in the paediatric oncology service at the Archet hospital (CHU). A consultation in oncogenetics is suggested to each family and insistently when a known syndrome is suspected. This consultation is also about to provide an other kind of care, in an other hospital, focused on the family with the aim to free of guilt the parents. Psychological care for families is in backdrop as they can express freely their questioning. Results: Twenty one families have been seen and fifteen different types of cancers recorded: mostly haematological cancers and neurological cancers. For each family, a pedigree was drawn. Data concerning the child’s disease and familial data were gathered. Most of the time, these information led to reassure the families. Therefore two Li and Fraumeni syndrome have been evoked. The first child suffered from a plexus choroid carcinoma and the second one had two distinct cancers: a nephroblastoma and a medulloblastoma. On the other hand, 2 children had had a LAL within a family with history of malignant haemopaties. Interestingly, 3 children with isolated LAL in the family where suggested to contribute to a research trial. Conclusions: This oncogenetic pediatric consultation allows to detect known hereditary predisposition syndromes and to contribute to researches in paediatric oncology. Above all, this strong bound between the oncogentics department and the pediatric oncology service permitted to reach an objective: offering families a specialised consultation with psychological support with a gap from disease.

1975 ◽  
Vol 2 (3) ◽  
pp. 299-333 ◽  
Author(s):  
T. M. S. Priestly

Summary The first family-tree diagram in August Schleicher’s (1821–68) published work appeared in 1853, seven years after his first printed discussion of the family-tree concept. In 1853 there also appeared Čteni o srovnavaci mluvnici slovanské by the Czech scholar František Ladislav Čelakovský (1799–1852); this book also contained a family-tree diagram. Since Čelakovský and Schleicher were contemporaries in Prague for over two years, their interrelationship is of interest: was this rivalry of collaboration? At first sight, a coincidence seems improbable. In the available work on and by Schleicher, Čelakovský is never mentioned; in the writings on and by Čelakovský, Schleicher’s name is never linked to his. However, the two had very many common interests. Apart from being colleagues at Charles University, they shared the same friends and enemies, were both interested in music and botany, and so on. Moreover, both were working on Slavic Historical Linguistics during the period in question. On the other hand, their personalities were such that the possibility of a mutual antipathy must not be excluded. Given the background to Čelakovský’s life and work, including the legends of the common origin of the Slavs and the obviously close interrelationships of the Slavic languages; the burgeoning of interest in Slavic history and linguistics, and in Panslavicism; the popularity of genealogy; and the developments in classificatory techniques along natural scientific lines, it is argued that Čela-kovský’s depiction of a family-tree for the Slavic languages could be quite naturally expected from him at this point in time, without any influence from Schleicher. On the other hand, Schleicher’s first family-tree diagrams were the next logical step in his own development. Moreover, the actual form of the diagrams in question suggests that they may indeed have been developed independently. This puzzle in the history of linguistics remains unsolved: collaboration, rivalry, and coincidence are all possible.


1915 ◽  
Vol 61 (252) ◽  
pp. 95-98
Author(s):  
T. C. Mackenzie

The Inverness Lunacy District, which was formed after the passing of the Lunacy Act of 1857, comprises the four counties of Nairn, Inverness, Ross, and Sutherland, and is of very large extent. Its area is, roughly, one-third of the total area of Scotland, and includes the greater part of the Highlands. Its population, on the other hand, is extremely sparse, and has been steadily decreasing during the last fifty years. It is a district in which there has been much intermarriage of relatives, and which is less open and accessible than most of the rest of Scotland to the factors that have brought about such great changes in the general life of the country during the last fifty years. In recent years, however, the extension of railways, and the wide use of motor cars, have done much to diminish this degree of isolation and remoteness.


Author(s):  
Elena A. Andrushchenko ◽  

D.S. Merezhkovsky’s play “Romantics” (1917) rarely attracts a researcher’s interest, although it is a notable attempt to revisit the rich material on the family history of the Bakunins contained in A.A. Kornilov’s work “Mikhail Bakunin’s young years. From the history of Russian romanticism” (1915). Merezhkovsky’s “bookishness” in the play is apparent in the creation of the idyllic image of Pryamukhino, where he relied on Kornilov’s book and composed a stylization, in which he handled “someone else’s” text and “point of view”. The stylization is reflected in the “estate topos”, which acts as a decoration for the characters’ intellectual aspirations. Coupled with intertext and mythopoetics, it establishes a myth of the intelligentsia’s religious communality, which Merezhkovsky had been developing in his fiction and public writings of those years. These have common motives of paradise, sacrifice, celibacy, unconscious Christianity, duality, detachment. The properties of the “estate topos” in “Romantics” are such that, on the one hand, it is related to the source, while on the other hand each of its elements is integrated into a particular sequence identifiable by its purpose in “estate” literature. This purports to reflect the reality, but is actually the reflection of its reflection; it binds the events to a concrete time and space, yet also affirms the idea of a timeless, universal realization, which is in line with Merezhkovsky’s mythopoetic creative consciousness.


2017 ◽  
Vol 13 (2) ◽  
pp. 187
Author(s):  
Putu Agung Nara Indra

<p><strong>Abstrak</strong></p><p>Perjalanan konflik antara pemerintah Filipina dengan kelompok-kelompok separatis di Filipina Selatan memunculkan beragam kelompok militan Islam seperti MILF, Abu Sayyaf, dan yang paling mutakhir, Kelompok Maute. .Banyaknya kelompok militan yang muncul berawal dari perpecahan-perpecahan di dalam kelompok-kelompok militan tradisional di Filipina Selatan khususnya MNLF dan MILF. Fenomena perpecahan ini akhirnya memunculkan kelompok-kelompok sempalan yang kerap terlibat pertempuran di antara mereka sendiri. Di sisi lain, kelompok-kelompok tersebut justru memiliki latar belakang ikatan keluarga yang sangat erat. Tulisan ini menyoroti tentang peranan jaringan keluarga di dalam keberadaan kelompok-kelompok militan di Filipina Selatan khususnya Kelompok Maute. Kelompok Maute dapat berkembang pesat karena pendiri dan sebagian besar anggotanya memiliki hubungan keluarga dengan kelompok Moro Islamic Liberation Front. Ikatan keluarga ini akhirnya menjadi pelindung sekaligus faktor penting bagi berkembangnya radikalisme Kelompok Maute.</p><p>Kata kunci: <em>Filipina Selatan, kelompok radikal Islam, MILF, Kelompok Maute, ikatan keluarga.</em></p><p> </p><p><strong>Abstract</strong></p><p>The history of conflict between Philippines government and separatist group in Southern Phillipines area has formed many radical Islamic groups such as, MILF, Abu Sayyaf, and Maute group. The emergence of these groups was caused by the schism in the older militant groups such as MNLF and MILF. However, the disunity of the older militant groups and the emergence of the so called “splinter groups” finally created conflicts among them. On the other hand, those groups bear resemblance in their family origins. This article highlighted the family networking inside the radical Islamic groups especially the Maute group. This group can grow rapidly because of the family bond between their founders and members with the Moro Islamic Liberation Front (MILF). The family bond became their protector and also vital point for the rise of radicalism in the Maute group.</p>Keyword: <em>Southern Philippines, radical Islamic groups, MMILF, Maute group, family bond. </em>


2014 ◽  
Vol 58 (1) ◽  
pp. 13-22
Author(s):  
Roman Wituła ◽  
Edyta Hetmaniok ◽  
Damian Słota

Abstract In the paper we present the selected properties of composition relation of the convergent and divergent permutations connected with commutation. We note that a permutation on ℕ is called the convergent permutation if for each convergent series ∑an of real terms, the p-rearranged series ∑ap(n) is also convergent. All the other permutations on ℕ are called the divergent permutations. We have proven, among others, that, for many permutations p on ℕ, the family of divergent permutations q on ℕ commuting with p possesses cardinality of the continuum. For example, the permutations p on ℕ having finite order possess this property. On the other hand, an example of a convergent permutation which commutes only with some convergent permutations is also presented.


2016 ◽  
Vol 3 (01) ◽  
Author(s):  
Shlesha Singh ◽  
Mrinalini Pandey

Organizations are these days realizing the importance of women in the workforce and to tap that talent, organizations are now-a-days putting extra efforts. Workplaces were designed keeping men in mind and which has been intercepting women from continuing the competitive jobs and career along with the family responsibilities. On the other hand, there are various workplace barriers which are adding to the other problems. Women face several barriers at the workplace like sexual harassment, glass ceiling and gender stereotype.


1895 ◽  
Vol 2 (12) ◽  
pp. 529-539 ◽  
Author(s):  
H. A. Nicholson ◽  
J. E. Marr

Since the remarkable paper by Professor Lapworth “On an Improved Classification of the Rhabdophora” was published in the Geological Magazine for 1873, a great deal of fresh information has been gathered as to these interesting fossils; but the classification given in that paper, though to some extent confessedly artificial, is still generally adhered to. Observations made by the authors in recent years lead them to suppose that that classification will in the future undergo considerable modification; but in the present state of our knowledge it serves a purpose so useful, that it is not our intention to propose any immediate change in it. Our object, on the other hand, is to bring forward certain conclusions which we have independently reached, and which will, we believe, enhance the value of Graptolites to the stratigraphical geologist, and lead to results important to the biologist. Our conclusions are based upon an examination of a large number of forms generally referred to the family Dichograptidæ; but, as we propose very briefly to indicate, they affect the relationships of Graptolites belonging to other families also.


2016 ◽  
Vol 2 (4) ◽  
Author(s):  
Robert Freidin ◽  
Juan Uriagereka ◽  
David Berlinski

The following remarks attempt to place Jean-Roger Vergnaud’s letter to Noam Chomsky and Howard Lasnik more centrally within the history of modern generative grammar from its inception to the present.


Zootaxa ◽  
2021 ◽  
Vol 5051 (1) ◽  
pp. 346-386
Author(s):  
SÜPHAN KARAYTUĞ ◽  
SERDAR SAK ◽  
ALP ALPER ◽  
SERDAR SÖNMEZ

An attempt was made to test if Lourinia armata (Claus, 1866)—as it is currently diagnosed—represents a species complex. Detailed examination and comparisons of several specimens collected from different localities suggest that L. armata indeed represents a complex of four closely related morphospecies that can be differentiated from one another by only detailed observations. One of the four species is identified as Lourinia aff. armata and the other three species are described as new to science and named as Lourinia wellsi sp. nov., L. gocmeni sp. nov., and L. aldabraensis sp. nov. Detailed review of previous species records indicates that the genus Lourinia Wilson, 1924 is distributed worldwide. Ceyloniella nicobarica Sewell, 1940, originally described from Nicobar Island and previously considered a junior subjective synonym of L. armata is reinstated as Lourinia nicobarica (Sewell, 1940) comb. nov. on the basis of the unique paddle-shaped caudal ramus seta V. It is postulated that almost all of these records are unreliable in terms of representing true Lourinia aff. armata described herein. On the other hand, the comparative evaluation of the illustrations and descriptions in the published literature indicates the presence of several new species waiting to be discovered in the genus Lourinia.                 It has been determined that, according to updated modern keys, the recent inclusion of the monotypic genus Archeolourinia Corgosinho & Schizas, 2013 in the Louriniidae is not justified since Archeolourinia shermani Corgosinho & Schizas, 2013 does not belong to this family but should be assigned to the Canthocamptidae. On the other hand, it has been argued that the exact phylogenetic position of the Louriniidae still remains problematic since none of the diagnostic characters supports the monophyly of the family within the Oligoarthra. It has also been argued that the close relationship between Louriniidae and Canthocamptidae is supported since both families share the homologous sexual dimorphism (apophysis) on P3 endopod. The most important characteristic that can possibly be used to define Louriniidae is the reduction of maxilliped.  


2016 ◽  
Vol 11 (1) ◽  
Author(s):  
William Skiles

This article examines the nature and frequency of comments about Jews and Judaism in sermons delivered by Confessing Church pastors in the Nazi dictatorship.  The approach of most historians has focused on the history of antisemitism in the German Protestant tradition—in the works, pronouncements, and policies of the German churches and its leading figures.  Yet historians have left unexamined the most elemental task of the pastor—that is, preaching from the pulpit to the German people.  What would the average German congregant have heard from his pastor about the Jews and Judaism on any given Sunday?  I searched German archives, libraries, and used book stores, and analyzed 910 sermon manuscripts that were produced and disseminated in the Nazi regime.  I argue that these sermons provide mixed messages about Jews and Judaism.  While on the one hand, the sermons express admiration for Judaism as a foundation for Christianity, an insistence on the usage of the Hebrew Bible in the German churches, and the conviction that the Jews are spiritual cousins of Christians.  On the other hand, the sermons express religious prejudice in the form of anti-Judaic tropes that corroborated the Nazi ideology that portrayed Jews and Judaism as inferior: for instance, that Judaism is an antiquated religion of works rather than grace; that the Jews killed Christ and have been punished throughout history as a consequence.  Furthermore, I demonstrate that Confessing Church pastors commonly expressed anti-Judaic statements in the process of criticizing the Nazi regime, its leadership, and its policies.


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