Targeted Imaging and Therapeutic Technologies in Neuroregeneration

2021 ◽  
pp. 101-120
Author(s):  
Jelena M. Janjic ◽  
Mihály Balogh ◽  
Sandeep Kumar Reddy Adena ◽  
Amanda Fitzpatrick ◽  
John A. Pollock ◽  
...  
Keyword(s):  
Targeted Imaging

Radiolabeled Peptide Probes for Liver Cancer Imaging

2020 ◽  
Vol 27 (41) ◽  
pp. 6968-6986
Author(s):  
Rui Cao ◽  
Hongguang Liu ◽  
Zhen Cheng
Keyword(s):  
Liver Cancer ◽  
Cancer Diagnosis ◽  
Cancer Imaging ◽  
Growth Factor Receptor ◽  
Targeted Imaging ◽  
Cancer Death ◽  
Binding Properties ◽  
Radiolabeled Peptides ◽  
Epidermal Growth ◽  
Peptide Probes

Liver cancer/Hepatocellular Carcinoma (HCC) is a leading cause of cancer death and represents an important cause of mortality worldwide. Several biomarkers are overexpressed in liver cancer, such as Glypican 3 (GPC3) and Epidermal Growth Factor Receptor (EGFR). These biomarkers play important roles in the progression of tumors and could serve as imaging and therapeutic targets for this disease. Peptides with adequate stability, receptor binding properties, and biokinetic behavior have been intensively studied for liver cancer imaging. A great variety of them have been radiolabeled with clinically relevant radionuclides for liver cancer diagnosis, and many are promising imaging and therapeutic candidates for clinical translation. Herein, we summarize the advancement of radiolabeled peptides for the targeted imaging of liver cancer.

scholarly journals VEGF receptor targeted imaging of angiogenic response to limb ischemia in diabetic vs. non-diabetic Yucatan minipigs

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Lynne L. Johnson ◽  
Jordan Johnson ◽  
Ziad Ali ◽  
Yared Tekabe ◽  
Rebecca Ober ◽  
...  
Keyword(s):  
Limb Ischemia ◽  
Vegf Receptor ◽  
Targeted Imaging ◽  
Angiogenic Response

Novel multifunctional nano-hybrid polyhedral oligomeric silsesquioxane-based molecules with high cell permeability: molecular design and application for diagnosis and treatment of tumors

Nanoscale ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 2982-2994
Author(s):  
Gang Wei ◽  
Kezhen Zhang ◽  
Yuanlong Gu ◽  
Shanyi Guang ◽  
Jihong Feng ◽  
...  
Keyword(s):  
Folic Acid ◽  
Molecular Design ◽  
Polyhedral Oligomeric Silsesquioxane ◽  
Cell Permeability ◽  
Targeted Imaging ◽  
High Cell ◽  
One Pot ◽  
Peg 400 ◽  
Multifunctional Molecules ◽  
Oligomeric Silsesquioxane

Octathiol POSS was used to connect PEG-400, hexene, folic acid, fluorescein, and thioguanine using a simple and efficient photo-initiated one-pot method to prepare multifunctional molecules, which have targeted imaging and therapeutic functions.

Recent Progress in Functional Peptides Designed for Tumor-targeted Imaging and Therapy

2021 ◽  
Author(s):  
Xingyu Wang ◽  
Yi-Hui Wang ◽  
Zhen Song ◽  
Xin-Yuan Hu ◽  
Jiping Wei ◽  
...  
Keyword(s):  
Recent Progress ◽  
Targeted Imaging ◽  
Medical Field ◽  
Diagnosis And Therapy ◽  
Low Toxicity ◽  
Functional Peptides ◽  
Living Organisms

The diagnosis and therapy of tumors are challenging problems in the medical field. Peptides are derived from living organisms with excellent biocompatibility, low-toxicity/non-toxicity, and negligible immunogenicity, and they have been...

scholarly journals Identifying Biomarkers in Lymph Node Metastases of Esophageal Adenocarcinoma for Tumor-Targeted Imaging

2020 ◽  
Vol 24 (2) ◽  
pp. 191-200 ◽  
Author(s):  
D. J. J. M. de Gouw ◽  
M. Rijpkema ◽  
T. J. J. de Bitter ◽  
V. M. Baart ◽  
C. F. M. Sier ◽  
...  
Keyword(s):  
Lymph Node ◽  
Esophageal Adenocarcinoma ◽  
Lymph Node Metastases ◽  
Targeted Imaging ◽  
Node Metastases

Multifunctional quantum dot–polypeptide hybrid nanogel for targeted imaging and drug delivery

Nanoscale ◽  
2014 ◽  
Vol 6 (19) ◽  
pp. 11282-11292 ◽  
Author(s):  
Jie Yang ◽  
Ming-Hao Yao ◽  
Lang Wen ◽  
Ji-Tao Song ◽  
Ming-Zhen Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dot ◽  
Cancer Diagnosis ◽  
Targeted Imaging ◽  
New Class

A new class of multifunctional quantum dot (QD)–polypeptide hybrid nanogel with targeted imaging and drug delivery properties is reported as a nanocarrier for use in cancer diagnosis, imaging, and therapy.

Sign in / Sign up

Export Citation Format

Share Document