Therapeutic Protein Delivery Systems

2022 ◽  
pp. 345-380
Author(s):  
Sarfaraz K. Niazi
Keyword(s):  
Protein Delivery ◽  
Delivery Systems ◽  
Therapeutic Protein

Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery

2015 ◽  
Vol 3 (43) ◽  
pp. 8477-8485 ◽  
Author(s):  
Yuting Niu ◽  
Meihua Yu ◽  
Jun Zhang ◽  
Yannan Yang ◽  
Chun Xu ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Silica Nanoparticles ◽  
Protein Delivery ◽  
Therapeutic Protein ◽  
Antibody Delivery

Silica nanoparticles with controllable surface roughness have been successfully prepared for therapeutic anti-pAkt antibody delivery.

Photoenhanced cytosolic protein delivery based on a photocleavable group-modified dendrimer

Nanoscale ◽  
2021 ◽  
Author(s):  
Yafei Li ◽  
Yang Zhou ◽  
Tianyi Wang ◽  
Kaiqi Long ◽  
Yaming Zhang ◽  
...  
Keyword(s):  
Protein Delivery ◽  
Delivery Systems ◽  
Cytosolic Protein

Numerous recently developed therapies have highlighted the advantages of using proteins as therapeutics. However, in many protein delivery systems, the complicated carrier designs, low loading content, and off-targeting phenomenon have...

Peptide and Protein Delivery Using New Drug Delivery Systems

2013 ◽  
Vol 30 (4) ◽  
pp. 293-329 ◽  
Author(s):  
Ashish Jain ◽  
Aviral Jain ◽  
Arvind Gulbake ◽  
Satish Shilpi ◽  
Pooja Hurkat ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Protein Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
New Drug

Bone Morphogenetic Protein Delivery Systems

Spine ◽  
2002 ◽  
Vol 27 (Supplement) ◽  
pp. S16-S23 ◽  
Author(s):  
Howard Seeherman ◽  
John Wozney ◽  
Rebecca Li
Keyword(s):  
Bone Morphogenetic Protein ◽  
Protein Delivery ◽  
Delivery Systems ◽  
Morphogenetic Protein

scholarly journals Extracellular Vesicles as Natural Nanosized Delivery Systems for Small-Molecule Drugs and Genetic Material: Steps towards the Future Nanomedicines

2015 ◽  
Vol 18 (3) ◽  
pp. 396 ◽  
Author(s):  
Mustafa Kotmakçı ◽  
Vildan Bozok Çetintaş
Keyword(s):  
Extracellular Vesicles ◽  
Small Molecule ◽  
Protein Delivery ◽  
Drug Loading ◽  
Genetic Material ◽  
Delivery Systems ◽  
Small Molecule Drugs ◽  
The Common ◽  
Therapeutic Protocols ◽  
Targeting Ability

A new platform for drug, gene and peptide-protein delivery is emerging, under the common name of “extracellular vesicles”. Extracellular vesicles (EVs) are 30-1000 nm-sized cell-derived, liposome-like vesicles. Current research on EVs as nano-delivery systems for small-molecule drugs and genetic material, reveal that these tiny, biologically-derived vesicles carry a great potential to boost the efficacy of many therapeutic protocols. Several features of EVs; from efficacy to safety, from passive to active targeting ability, the opportunity to be biologically or chemically labelled, and most importantly, their eobiotic origin make them promising candidate for development of the next generation personalized nanomedicines. The aim of this article is to provide a view on the current research in which EVs are used as drug/genetic material delivery systems. Their application areas, drug loading and targeting strategies, and biodistribution properties are discussed.This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

Predicting protein instability in sustained protein delivery systems using spectral-phase interference

Biomaterials ◽  
2012 ◽  
Vol 33 (6) ◽  
pp. 1929-1938 ◽  
Author(s):  
Nina Seidel ◽  
Johannes Sitterberg ◽  
Wolfgang Vornholt ◽  
Udo Bakowsky ◽  
Michael Keusgen ◽  
...  
Keyword(s):  
Protein Delivery ◽  
Delivery Systems ◽  
Spectral Phase ◽  
Phase Interference ◽  
Protein Instability

Self-Assembled PAA-Based Nanoparticles as Potential Gene and Protein Delivery Systems

2013 ◽  
Vol 13 (5) ◽  
pp. 641-649 ◽  
Author(s):  
Peter C. Griffiths ◽  
Nicolo Mauro ◽  
Damien M. Murphy ◽  
Emma Carter ◽  
Simon C. W. Richardson ◽  
...  
Keyword(s):  
Protein Delivery ◽  
Delivery Systems ◽  
Self Assembled

Biomimetic calcium phosphate coatings as bone morphogenetic protein delivery systems in spinal fusion

2011 ◽  
Vol 11 (6) ◽  
pp. 560-567 ◽  
Author(s):  
Kamran Majid ◽  
Michael D. Tseng ◽  
Kevin C. Baker ◽  
Alma Reyes-Trocchia ◽  
Harry N. Herkowitz
Keyword(s):  
Calcium Phosphate ◽  
Spinal Fusion ◽  
Bone Morphogenetic Protein ◽  
Protein Delivery ◽  
Delivery Systems ◽  
Morphogenetic Protein ◽  
Phosphate Coatings ◽  
Calcium Phosphate Coatings

scholarly journals Next Generation Delivery System for Proteins and Genes of Therapeutic Purpose: Why and How?

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Ashish Ranjan Sharma ◽  
Shyamal Kumar Kundu ◽  
Ju-Suk Nam ◽  
Garima Sharma ◽  
C. George Priya Doss ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Delivery System ◽  
Delivery Systems ◽  
Therapeutic Protein ◽  
Gene Delivery System ◽  
Next Generation ◽  
Therapeutic Purpose ◽  
Detailed Explanation ◽  
Or Gene

Proteins and genes of therapeutic interests in conjunction with different delivery systems are growing towards new heights. “Next generation delivery systems” may provide more efficient platform for delivery of proteins and genes. In the present review, snapshots about the benefits of proteins or gene therapy, general procedures for therapeutic protein or gene delivery system, and different next generation delivery system such as liposome, PEGylation, HESylation, and nanoparticle based delivery have been depicted with their detailed explanation.

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