scholarly journals Habituation in mosquito larvae Aedes aegypti is context-specific

2021 ◽  
Author(s):  
Pietrantuono A.L. ◽  
Aguirre M.B. ◽  
Bruzzone O.A. ◽  
Guerrieri F.J.
Keyword(s):  
Aedes Aegypti ◽  
Learning Curve ◽  
Selection Procedure ◽  
Mosquito Larvae ◽  
Context Specificity ◽  
Habituation Rate ◽  
Risk Of Predation ◽  
Response Increase ◽  
Context Specific ◽  
Study Context

Mosquito larvae live in water and perform a stereotyped escape response when a moving object projects its shadow on the surface, indicating potential risk of predation. Repeated presentations of the shadow induce a decrease in the response due to habituation, a form of non-associative learning defined as the progressive and reversible decrease in response to a specific reiterative innocuous stimulus. Nevertheless, habituation can be context-specific, which indicates an association between the context and the stimulus. The aim of this work was to study context-specificity in habituation in mosquito larvae Aedes aegypti. Larvae were individually placed in Petri dishes. Underneath, black, white or black-white striped cardboards were placed as backgrounds (visual context). Larvae were presented with a shadow produced by a cardboard square (training) over the course of 15 trials. After the fifteenth trial, the background was shifted and the stimulus was presented once again (test). To analyse habituation in different contexts, we developed a series of learning curve models. We performed a Bayesian model selection procedure using those models and the data from the experiments to find which model best described the results. The selected model was a Power-Law learning curve with six parameters (habituation rate, context-specific asymptotic habituation response -with one parameter per context, i.e. 3 parameters-, response-increase, and autocorrelation) describing the whole experimental setup with a generalised r2 of 0.96. According to the model, a single habituation rate would indicate that habituation was independent of the context, whilst asymptotic habituation would be context-specific. If the background was shifted after training, there was an increase in the response in the test, evincing context specificity in habituation.

Polycomb genes role in cancer pathophysiology is offering targets for therapeutics including gene therapy

2021 ◽  
Author(s):  
Moataz Dowaidar
Keyword(s):  
Catalytic Activity ◽  
Detailed Understanding ◽  
The Core ◽  
Chromatin Regulators ◽  
Genetic Modifications ◽  
Anti Cancer ◽  
The Many ◽  
The One ◽  
Context Specific ◽  
Study Context

Several phenotypes can come from transcription regulation. Sequence-specific transcription factors are needed to effectively execute transcriptional programs, however they are often not operating alone. Polycomb PcG proteins are a well-known class of chromatin regulators found in Drosophila melanogaster and other species, including humans. As time passed, the concept of a PCG gene or protein shifted from the original phenotypic meaning of mutant flies to the contemporary biochemical description. PCG genes and proteins are under investigation for their critical contributions to physiology and their cancer treatment potential. Adding additional PcG members, with substantial responsibilities in PRC modulation, has opened new routes of inquiry in the issue. It is still needed to discover the many PRC variations' roles and how their catalytic activity is controlled. This review covers mutually exclusive PRC2 variants and employs a technique like the one used for PRC1 variants. Based on current biochemical findings, these classifications are valid. More auxiliary PcG subunit research is needed for now. Moreover, it is unknown how many PRC cell variations occur (hypothetically, there could be more than 100 different PRC variants).In order to fully elucidate the new PcG proteins and complexes, it is necessary to perform comprehensive research. We must study context-specific genetic modifications to better provide remedies. Current anti-cancer drugs target mainly the core subunits and catalytic activity of PRC2 and PRC1, and understanding these functions is critical. Targeting each particular activity that has been deregulated might be rather beneficial. PCG proteins are involved in oncogenesis, tumor suppression, and development/congenital illness as well. PcG involvement in cancer, once revealed, would be intriguing. Successful and effective therapeutic therapies will be helped by a detailed understanding of the pathways that contain PcG proteins.

scholarly journals Effects of two formulations based on Bacillus thuringiensis subsp. israelensis on Aedes aegypti mosquito larvae under laboratory conditions

2008 ◽  
Vol 23 (4) ◽  
pp. 251-258
Author(s):  
Milenka Peric ◽  
Mirjana Prijovic ◽  
Goran Andric
Keyword(s):  
Bacillus Thuringiensis ◽  
Aedes Aegypti ◽  
Aqueous Suspension ◽  
Pure Water ◽  
Clay Content ◽  
Experimental Period ◽  
Mosquito Larvae ◽  
Water Dispersible ◽  
Bacillus Thuringiensis Subsp ◽  
Zero Time

Toxicity and persistence of two formulations based on Bacillus thuringiensis subsp. israelensis applied to Aedes aegypti mosquito larvae were tested under laborabory conditions. The formulations were: a) water dispersible granules (product VectoBac WDG), and b) aqueous suspension (product VectoBac 12AS). The effects of both products on mosquito larvae were tested immediately after their dilution in pure water (zero time) and in 1-, 2-, 8- and 13-day old solutions. The two products were also tested in mixtures of water and clay at a rate of 0.5 g clay/150 ml water immediately after product dilution, and in one-day old solutions containing 0.1 and 0.05 g of clay in the same amount of water. The product VectoBac WDG was persistent and highly effective against Ae. aegypti larvae in pure water after the longest experimental period of 13 days, and significantly more effective than VectoBac 12AS at equal rates of application. The effectiveness of VectoBac 12AS weakened significantly after 8 and 13 days of treatment, compared to the effects at zero time and in 1- and 2-day old solutions. High clay content in water significantly reduced the larvicidal effectiveness of both products, indicating its possible compromising role during product application in practice.

scholarly journals Bioefficacy of some insect growth regulators and plant extracts against mosquito larvae of Aedes aegypti

2019 ◽  
Vol 6 (1) ◽  
pp. 001-006
Author(s):  
Mohamd R. Al-Zahrani ◽  
Jazem A. Mahyoub ◽  
Khalid M. Al-Ghamdi ◽  
Habeeb M. Al-Solami
Keyword(s):  
Aedes Aegypti ◽  
Growth Regulators ◽  
Plant Extracts ◽  
Mosquito Larvae ◽  
Insect Growth Regulators ◽  
Insect Growth

scholarly journals The Toxicity of Srikaya Seed Granules (Annona squamosa L.) with Different Heating Temperatures Against the Larva of Aedes aegypti L.

BIOEDUKASI ◽  
2020 ◽  
pp. 1
Author(s):  
Rima Gloria Purwanto ◽  
Dwi Wahyuni ◽  
Joko Waluyo
Keyword(s):  
Aedes Aegypti ◽  
Mosquito Control ◽  
Heating Temperature ◽  
Probit Analysis ◽  
Mosquito Larvae ◽  
Annona Squamosa ◽  
Forest Region ◽  
Randomized Design ◽  
Significant Difference ◽  
Lower Temperature

Abstract: Aedes aegypti L. is a mosquito carrying dengue virus that causes dengue fever, especially in Southeast Asia which is a tropical rain forest region which is a habitat for mosquito growth. Aedes aegypti L. mosquito control is carried out by chemical means of fogging and using abate but this control actually causes Aedes aegypti L. mosquitoes to become resistant or immune to chemical drugs so that a new breakthrough is created by making bioinsecticides biologically to eradicate the Aedes aegypti L. mosquito. with characteristics that are environmentally friendly and do not kill non-target animals and cause the Aedes aegypti L. mosquito not to become resistant. To be able to realize this desire so that the sugar cane granules extract of Annona squamosa L. containing active compounds in the form of annonain and squamosin so that they are toxic to Aedes aegypti L. mosquito larvae. Further research is to test the heating temperature level of the granules of Annona squamosa L. extract temperature of 40 ° C and 60 ° C which is more deadly of Aedes aegypti L. mosquito larvae. This research method uses a completely randomized design with four repetitions. The temperature of 60 ° C uses concentrations of 1 ppm, 6 ppm, 12 ppm, 18 ppm, 24 ppm and 30 ppm. As for the temperature of 40 ° C using concentrations of 1 ppm, 7 ppm, 14 ppm, 21 ppm, 28 ppm, and 35 ppm, each temperature compared with aquadest and abate. Data analyzed using probit analysis to determine the LC50, then followed by a statistical test paired sample T-test with SPSS to find out a significant difference between heating temperatures of 40 ° C to 60 ° C. These results then show that a higher temperature of 60 ° C has a higher level of toxicity compared to a lower temperature of 40 ° C.

Occupation-Specific Precursors of Stress among Greek Police Officers: The Roles of Rank and Gender

2009 ◽  
Vol 11 (3) ◽  
pp. 334-344 ◽  
Author(s):  
Alexander-Stamatios Antoniou
Keyword(s):  
Police Officers ◽  
Low Rank ◽  
Context Specificity ◽  
Women Police Officers ◽  
Work Related ◽  
Management Interventions ◽  
Women Police ◽  
And Gender ◽  
Work Family ◽  
Context Specific

Although assessment of stress is typically performed using generic stress questionnaires, the context-specificity and generalisability of such assessments are often ignored. This study explored the differences in perceptions of work-related stressors in male/female and high/low rank police officers in Greece, by the application of a context-specific measure. 512 police officers representing the Hellenic police force responded to a questionnaire assessing precursors to work stress, and perceived level of stress. Results revealed that the nature of occupational stressors pertinent to Greek police officers differed as a function of their gender and their rank. Males and females differed in their perceptions of stressfulness of the context-specific issues assessed, with females reporting significantly higher stress in 21 work and organisational issues. High and low rank police officers also differed in their perceptions of stressfulness, with high rank police officers reporting more stress overall. The study highlighted the facts that work issues pertaining to female police officers' work and work issues pertaining to high and low rank police officers are of a specific nature. Women police officers are concerned more with issues related to career opportunities, roles and responsibility, and work–family issues. Risk assessment and stress management interventions should take these into consideration. Context-specificity is a good way forward in assessments of stress, and measures may need to be refined.

scholarly journals Glyphosate impairs learning in Aedes aegypti mosquito larvae at field-realistic doses

2018 ◽  
Vol 221 (20) ◽  
pp. jeb187518 ◽  
Author(s):  
Hugo Baglan ◽  
Claudio R. Lazzari ◽  
Fernando J. Guerrieri
Keyword(s):  
Aedes Aegypti ◽  
Mosquito Larvae

scholarly journals A comparison of aquaporin expression in mosquito larvae (Aedes aegypti) that develop in hypo-osmotic freshwater and iso-osmotic brackish water

PLoS ONE ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. e0234892
Author(s):  
Lidiya Misyura ◽  
Elia Grieco Guardian ◽  
Andrea Claire Durant ◽  
Andrew Donini
Keyword(s):  
Aedes Aegypti ◽  
Brackish Water ◽  
Mosquito Larvae

The accumulation of radioactive cesium, phosphorus, strontium, and yttrium by mosquito larvae and its relevance to radiation dose

1972 ◽  
Vol 50 (6) ◽  
pp. 767-770
Author(s):  
A. G. Scott ◽  
J. E. Guthrie
Keyword(s):  
Radiation Dose ◽  
Aedes Aegypti ◽  
Dose Rate ◽  
Radioactive Cesium ◽  
Mosquito Larvae ◽  
Radionuclide Concentration ◽  
Internal Radiation ◽  
Stage Of Development ◽  
Apparent Concentration ◽  
The Individual

Aedes aegypti (L.) larvae were reared in solutions of 137Cs, 32P, and 90Sr + 90Y and the apparent concentration ratios of the individual radionuclides which were accumulated are reported. A consideration of the significance of accumulation to the internal radiation dose delivered to the larvae reveals that larvae reared in identical concentrations of a radionuclide did not receive the same dose, nor were they exposed to the greatest dose-rate at the same stage of development. The probable dose to larvae reared in radioactive solutions cannot be calculated solely from a knowledge of the radionuclide concentration in the rearing medium.

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