Previous STI and risk of HIV infection in men

2003 ◽  
Vol 14 (5) ◽  
pp. 341-343 ◽  
Author(s):  
M Vall Mayans ◽  
J M Escribá

To determine the prevalence of a previous history of sexually transmitted infection (STI) and its influence as a risk factor for HIV infection among men tested for HIV, data from men having a voluntary HIV test at the STI Unit of Barcelona during a 6-month period of 1998 were analysed. Descriptive and logistic regression analysis were done to examine the prevalence of previous STI and factors associated with HIV infection. Prevalences of HIV were 5.6% in homo/bisexual and 0.5% in heterosexual men ( P<0.001). Risk factors for HIV were STI history: odds ratio (OR)=8.7 and homo/bisexual behaviour: OR=6.6; 19.8% of heterosexuals had a history of STI compared with 44.2% of homo/bisexual men ( P<0.01). A previous STI was associated with HIV seropositivity in homosexual men.

2020 ◽  
Vol 31 (3) ◽  
pp. 254-263
Author(s):  
Matthew P Hibbert ◽  
Caroline E Brett ◽  
Lorna A Porcellato ◽  
Vivian D Hope

Previous research has focused on acceptability of pre-exposure prophylaxis (PrEP) use, but few community-based studies have been conducted regarding actual use, and PrEP use in the context of sexualised drug use remains understudied. A national online cross-sectional study recruited men who have sex with men (MSM) via social media (April–June 2018). Multivariable logistic regression was used to investigate factors associated with PrEP use. Bivariate analyses compared engaging in condomless anal intercourse (CAI) under the influence of specific drugs and recent sexually transmitted infection (STI) diagnoses (past 12 months) between MSM taking PrEP and those not. Overall, 6% (99/1581) MSM reported current PrEP use. Factors associated with PrEP use were increasing age, recent genitourinary medicine (GUM) attendance (95% versus 45%, aOR = 6.25, 95%CI 2.05, 19.03), an HIV test in the past three months (89% versus 23%, aOR = 14.22, 95%CI 6.76, 29.90), and recent engagement in chemsex (21% versus 4%, aOR = 3.56, 95%CI 1.78, 7.11). MSM taking PrEP were more likely to have had an STI diagnosis (42% versus 8%), most commonly chlamydia (26% versus 3%) and gonorrhoea (25% versus 4%). Considering the elevated levels of self-reported STI diagnoses among those on PrEP, there was a high level of engagement with sexual health services, which may help reduce onward STI transmission.


2003 ◽  
Vol 14 (8) ◽  
pp. 526-531 ◽  
Author(s):  
P Moodley ◽  
P D J Sturm ◽  
C Connolly ◽  
A W Sturm

We showed an association between current infection with a recognized sexually transmitted infection (STI) pathogen and HIV infection in women but not in men with non-ulcerative genital disease. While the accuracy of recognition of male urethritis and genital ulcer syndromes is high, this is significantly less for non-ulcerative STIs in women. The symptoms associated with the latter have a broad differential diagnosis including conditions of a non-STI nature. Local sexually transmitted disease (STD) clinic attendees often comprise patients with and without STIs. We hypothesized that this may be responsible for the association of current STI pathogens and HIV in women. To identify a group of women that would be representative of a true STD clinic population we looked at those with a past history of treated genital ulcers. When we analysed in this subset the association of current STI pathogen and HIV infection, a pattern emerged that was comparable with that in men.


Aquichan ◽  
2020 ◽  
Vol 20 (4) ◽  
pp. 1-11
Author(s):  
Érica de Brito Pitilin ◽  
Vanessa Aparecida Gasparin ◽  
Debora Tavares de Resende e Silva ◽  
Jeane Barros de Souza ◽  
Fabiana Brum Haag

Objective: To identify the factors associated with hospitalizations due to congenital syphilis in neonates, based on the characteristics of prenatal care. Materials and method: A quantitative case-control study, conducted by applying a questionnaire to 65 puerperal women with their babies hospitalized from July to November 2017. The data were analyzed using logistic regression, according to the plan proposed in the hierarchical approach. Results: 20% of the hospitalizations were due to syphilis (cases) and 80% to other causes (control). The vulnerability risk (p = 0.036), previous history of sexually transmitted infection (p = 0,006), use of oral contraceptives (p = 0.011) and parity (p = 0.043) variables were statistically significant. The absence of the partner during the consultation (p = 0.028), failure to perform a rapid test for syphilis (p = 0.035) and educational activity for the partner (p = 0.033) were also associated with the occurrence of the outcome, in addition to the variables of the newborn: low birth weight (p = 0.025), not being on exclusive breastfeeding (p = 0.036) and not having had skin-to-skin contact (p = 0.043). Conclusions: Congenital syphilis has several risk factors for its occurrence. It was possible to observe that the assistance inequalities existing in care during the prenatal consultations directly reflect on the occurrence of this condition.


Author(s):  
Jeffrey Edwards ◽  
Avery Hinds ◽  
Nyla Lyons ◽  
Jonathan Edwards ◽  
Shauntelle Quammie ◽  
...  

A chart review study of the sexually transmitted infection (STI) prevalence among persons living with HIV (PLHIV) was conducted among STI clinic attendees in Trinidad between January 2012 and December 2012. Data were abstracted from client records to obtain the clinical and the laboratory diagnoses of STIs. Descriptive and bivariate analyses were conducted, and factors significantly associated with the presence of a STI were assessed using multiple logistic regression. During this period, 385 PLHIV were seen; 104 (27.0%) were newly HIV diagnosed and 281 (73.0%) had a known history of HIV infection; 135 (35.1%) were diagnosed with a STI. Patients with known HIV infection were more likely to be diagnosed with a STI than those who were newly diagnosed (odds ratios: 6.99; 95% confidence interval: 3.79-12.89). The STI prevalence was high among PLHIV in Trinidad, identifying them as a critical target group for public health interventions to prevent the spread of HIV and STIs.


2002 ◽  
Vol 13 (12) ◽  
pp. 843-846 ◽  
Author(s):  
T K Wickramasinghe ◽  
K E Rogstad

To identify factors associated with uptake of HIV testing a questionnaire was given to patients attending a GUM clinic over a three-week period. One hundred and twenty (69.4%) of 189 patients accepted and 53 (30.6%) refused testing. Variables associated with having a HIV test were: being tested previously ( P = 0.045), given a leaflet about testing ( P = 0.001), told about the window period ( P = 0.006), told about availability of counselling ( P = 0.030), given insurance advice ( P = 0.014), and a past history of sexually transmitted infections ( P = 0.044). Most patients perceived a low risk of being HIV positive ( n = 143, 75.7%) with no difference between those accepting or declining testing. The principal reason for testing was a check-up, and for refusal was a lack of perceived risk. Patients who are well informed about HIV testing are more likely to accept a test.


Author(s):  
Wynne Pereira Nogueira ◽  
Matheus Figueiredo Nogueira ◽  
Jordana de Almeida Nogueira ◽  
Maria Eliane Moreira Freire ◽  
Elucir Gir ◽  
...  

Abstract Objective: To estimate the prevalence of syphilis and associated factors in riverine communities. Method: This is a cross-sectional and analytical study carried out with 250 riverside dwellers living in five communities in the city of João Pessoa, state of Paraíba. Data were collected through interviews and rapid screening tests to investigate syphilis. Bivariate, logistic regression and weight of evidence analysis were performed to identify the association between risk factors and behavior variables and rapid test positivity. Results: he prevalence of syphilis was 11.6% (95%CI: 7.5–15.6). Riverside dwellers who have a previous history of Sexually Transmitted Infection (OR 8.00; 95%CI: 2.76–23.2), history of imprisonment (OR 7.39; 95%CI: 1.61–33.7) and who reported having more than two sexual partners in the last 12 months (OR 4.31; 95%CI: 1.55–11.9) were more likely to be positive for syphilis. Conclusion: High prevalence of syphilis among riverside dwellers and the presence of behavioral factors that increase vulnerability to acquiring the infection. The need to invest in preventive and screening strategies for syphilis in populations considered vulnerable is highlighted.


2021 ◽  
Author(s):  
Kennethea A. Wilson ◽  
Sarahmona M. Przybyla ◽  
Jacob Bleasdale ◽  
Steven Gabriel ◽  
Natalie Leblanc ◽  
...  

Abstract In the United States, low rates of pre-exposure prophylaxis (PrEP) awareness and utilization persist among Black adults. To date, few studies have assessed PrEP awareness and use among a nationally representative sample of Black adults. The present study explored factors associated with PrEP awareness and use among Black adults in the United States. Most participants were unaware of PrEP (71%). Those reporting a history of incarceration [aOR 1.73 (1.04, 2.90), p <.05] and lifetime sexually transmitted infection testing [aOR 1.76 (1.19, 2.59), p <.05] had greater odds of awareness. In the sample, only 6% of participants had ever taken PrEP. Those with a history of incarceration [aOR 9.96 (2.82, 35.14), p <.05], concurrent sexual partners [aOR 1.09 (1.00, 1.18), p <.05], and substance use during sex [aOR 4.23 (1.02, 17.48), p <.05] had greater odds of use. Interventions to improve PrEP uptake among Black adults must consider the contextual factors associated with awareness and use.


2016 ◽  
Vol 28 (6) ◽  
pp. 573-583 ◽  
Author(s):  
Jamie Frankis ◽  
Lisa Goodall ◽  
Dan Clutterbuck ◽  
Abdul-Razak Abubakari ◽  
Paul Flowers

Sexually transmitted infections (STIs) disproportionately affect men who have sex with men, with marked increases in most STIs in recent years. These are likely underpinned by coterminous increases in behavioural risks which have coincided with the development of Internet and geospatial sociosexual networking. Current guidelines advocate regular, annual sexually transmitted infection testing amongst sexually active men who have sex with men (MSM), as opposed to symptom-driven testing. This paper explores sexually transmitted infection testing regularity amongst MSM who use social and sociosexual media. Data were collected from 2668 men in Scotland, Wales, Northern Ireland and the Republic of Ireland, recruited via social and gay sociosexual media. Only one-third of participants report regular (yearly or more frequent) STI testing, despite relatively high levels of male sex partners, condomless anal intercourse and high-risk unprotected anal intercourse. The following variables were associated with regular STI testing; being more ‘out’ (adjusted odds ratio = 1.79; confidence interval = 1.20–2.68), HIV-positive (adjusted odds ratio = 14.11; confidence interval = 7.03–28.32); reporting ≥10 male sex partners (adjusted odds ratio = 2.15; confidence interval = 1.47–3.14) or regular HIV testing (adjusted odds ratio = 48.44; confidence interval = 28.27–83.01). Men reporting long-term sickness absence from work/carers (adjusted odds ratio = 0.03; confidence interval = 0.00–0.48) and men aged ≤25 years (adjusted odds ratio = 0.36; 95% confidence interval = 0.19–0.69) were less likely to test regularly for STIs. As such, we identify a complex interplay of social, health and behavioural factors that each contribute to men’s STI testing behaviours. In concert, these data suggest that the syndemics placing men at elevated risk may also mitigate against access to testing and prevention services. Moreover, successful reduction of STI transmission amongst MSM will necessitate a comprehensive range of approaches which address these multiple interrelated factors that underpin MSM's STI testing.


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