Outcome of management of brain abscess in children

Objective: To find out the outcome of management of brain abscess in children. Methods: This is prospective observational study conducted in the Department of Paediatric Neurosurgery at Children’s Hospital and Institute of Child Health, Multan from July 2014 to June 2017. Children up to the age of 14 years suffering from brain abscess were admitted. After taking clinical history, general and systemic physical examination and necessary investigations, abscess was evacuated and abscess wall excised after performing craniotomy. Data was collected on a predesigned performa. Results were analyzed and compared with national and international literature through statistical package for social sciences (SPSS-20). Results: Twenty five patients up to 14 years of age were included. Seventeen (68%) were male and eight (32%) female. Fever and vomiting were present in all 25 (100%) patients. Paranasal sinusitis was predisposing causative factor in 9(36%) followed by otitis media in 7 (28%). Abscess was present in frontal lobe in 9 (36%), temporoparietal region in 8 (32%), posterior fossa in 5 (20%) and multiple abscesses in 3 (12%). Craniotomy was performed, pus evacuated and abscess wall excised in all 25 (100%) patients. Three (12%) patients expired. Conclusion: Incidence of brain abscess can be decreased by treatment of its predisposing causes as sinusitis and otitis media. Small abscess less than 2cm can be treated with antibiotics. Complete evacuation of pus and excision of abscess wall after performing craniotomy along with appropriate antibiotics is gold standard management of brain abscess in children. doi: https://doi.org/10.12669/pjms.36.3.1087 How to cite this:Khan IU, Latif A, Ashraf M, Chishti MK, Sadiq S. Outcome of management of brain abscess in children. Pak J Med Sci. 2020;36(3):---------. doi: https://doi.org/10.12669/pjms.36.3.1087 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Current epidemiological trends of brain abscess: a clinicopathological study

Romanian Neurosurgery ◽

10.1515/romneu-2017-0067 ◽

2017 ◽

Vol 31 (3) ◽

pp. 414-421 ◽

Cited By ~ 1

Author(s):

Neha Singh ◽

Deepak Kumar Singh ◽

Rakesh Kumar ◽

Hanuman Prajapati

Keyword(s):

Brain Abscess ◽

Otitis Media ◽

Surgical Excision ◽

Clinical History ◽

Chronic Suppurative Otitis Media ◽

Suppurative Otitis Media ◽

Detailed Clinical History ◽

Haematogenous Spread ◽

Epidemiological Trends ◽

Spread Of Infection

Abstract Aims: To determine the current epidemiological trends, clinical presentation and commonest organism of brain abscess in this part of the country. Material and Methods: 104 cases admitted during August 2009 to July 2016 in the Department of neurosurgery of Dr RMLIMS Lucknow were included in the study. Detailed clinical history was taken and detailed neurological examination was done. Relevant laboratory investigations were done as needed along with CT scan and /or MRI brain. Patients were managed by aspiration or surgical excision and aspirated material sent for microbiological examination. Results were collected and analyzed. Results: Chronic suppurative otitis media (CSOM) was the commonest cause of infection in 54.81% cases. Trauma was encountered in 10.58%% cases. Other causes were haematogenous spread of infection, dental caries and immunodeficiency. No source could be identified in 23 patients (22.11%). Conclusion: Chronic suppurative otitis media (CSOM) is still a major cause of brain abscess in developing country like India which is a benign curable disease and should not be neglected. Prompt diagnosis and treatment allows immediate decompression of mass reduces duration of antibiotic stay and minimizes treatment cost.

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A Case of Invasive Fungal Otitis Media Progressed to Brain Abscess

Korean Journal of Otorhinolaryngology - Head and Neck Surgery ◽

10.3342/kjorl-hns.2014.57.7.484 ◽

2014 ◽

Vol 57 (7) ◽

pp. 484

Author(s):

Joon Seok Ko ◽

In Sung Park ◽

Seong-Ki Ahn ◽

Dong Gu Hur

Keyword(s):

Brain Abscess ◽

Otitis Media

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Meat Hook Injury Leading to Brain Abscess: A Rare Occurrence

Indian Journal of Neurotrauma ◽

10.1055/s-0041-1732789 ◽

2021 ◽

Author(s):

Batuk Diyora ◽

Gagan Dhall ◽

Mehool Patel ◽

Mazharkhan Mulla ◽

Nilesh More ◽

...

Keyword(s):

Brain Abscess ◽

Signs And Symptoms ◽

Penetrating Injury ◽

Perilesional Edema ◽

Delayed Complications ◽

The Right ◽

Time Of Presentation ◽

Local Examination ◽

Abscess Wall ◽

Primary Injury

AbstractTransorbital orbitofrontal penetrating injury by a nonmissile object is uncommon. The presentation of this injury varies. This injury can be easily missed during the initial clinical presentation, because the foreign body is sometimes not visible on local examination, the wound on the orbital skin is small, and very subtle signs are present. The patient can present with delayed complications of the primary injury. Our patient was a 33-year-old male who presented with an orbitofrontal injury with a meat hook. He had minor symptoms at the time of presentation, which were overlooked. Three weeks later, he developed signs and symptoms of raised intracranial pressure (ICP). Brain imaging revealed a peripheral rim of contrast-enhancing mass lesion in the right frontal lobe, extending into the right orbit with perilesional edema suggestive of posttraumatic brain abscess. Via right frontal craniotomy, pus was drained out and abscess wall was excised. The patient made good clinical recovery. A higher index of suspicion and sound knowledge of occult penetrating injury patterns is required in the cases of orbital injuries. Appropriate radiological imaging can lead to an earlier and accurate diagnosis, and can prevent its delayed sequela like brain abscess.

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Mixed brain abscess due to Streptococcus and Tuberculosis in a pregnant woman with favorable evolution. A case report

10.36879/jcmi.20.000123 ◽

2020 ◽

pp. 1-3

Keyword(s):

Brain Abscess ◽

Public Health Problem ◽

Elective Cesarean Section ◽

Histopathological Study ◽

Global Public Health ◽

Mother And Child ◽

Elective Cesarean ◽

Causes Of Mortality ◽

Abscess Wall

Tuberculosis is a global public health problem and is among the top ten causes of mortality in the world. We present the unusual case of a 37-year-old woman, referred for fever, progressive headache, nausea, vomiting and change in mental status. Brain imaging studies. showed a left frontal brain abscess with subfalcin herniation. As an urgent procedure, surgical drainage of the brain abscess was performed, and in the culture of pus there was growth of an anaerobic Streptococcus. The histopathological study of the abscess wall showed data on tuberculosis. The patient was pregnant at surgery, for about five weeks and received anti-tuberculous medications with close maternal fetal follow-up. Pregnancy came to term and was resolved by an elective cesarean section, both mother and child had a favorable evolution.

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Brain Abscess Complicating Otitis Media: A Spark Spreads Like Wildfire.

Southern Medical Journal ◽

10.1097/00007611-200510001-00045 ◽

2005 ◽

Vol 98 (Supplement) ◽

pp. S20

Author(s):

Harsha Gadadhar ◽

R Alay ◽

Mukta Panda

Keyword(s):

Brain Abscess ◽

Otitis Media

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Incidence of ear, nose and throat disorders in children: a study in a teaching hospital in Telangana

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20160065 ◽

2016 ◽

Vol 2 (1) ◽

pp. 26

Author(s):

Harika Surapaneni ◽

Shalini Singh Sisodia

Keyword(s):

Otitis Media ◽

Economic Status ◽

Clinical History ◽

Nasal Discharge ◽

X Rays ◽

Acute Tonsillitis ◽

Suppurative Otitis Media ◽

Socio Economic Status ◽

Nasal Diseases ◽

Nose And Throat

Background: ENT problems are very common among the children, especially diseases such as acute suppurative otitis media, acute tonsillitis, acute epiglottis, laryngotracheobronchitis, and rhinitis etc. Poor hygienic conditions, malnourishment, different socio-economic levels are also said to play a role in the prevalence of ENT disorders.Methods: 417 children between the ages of 0-15, attending the ENT department in our hospital were included in the study. General demographic details such as age, sex, socio-economic status, clinical history, and examination for common ENT complaints and disorders was taken for all patients. Otoscopy for ear examination for diseases such as otitis media, ear perforation and ear discharge anterior rhinoscopy for nasal discharge, airway obstruction and infection were performed Presence of any adenoid hypertrophy was looked for. Throat examination was performed for any sign of tonsillitis or pharyngitis. Appropriate investigations such as X-rays, culture and sensitivity, etc were performed where necessary. Results: 258 (61.9%) patients were females while there were 159 (38.1%) males. More than 45% cases who had disorders were concentrated in the 6-15 years age group. Almost 75% of the children were from lower socio-economic status. Otitis media among the ear diseases, rhinitis in the nasal diseases and pharyngitis followed by tonsillitis in the diseases of the throat was found to be the most common.Conclusions: Our study provides basic information of the prevalent disorders in ENT in our area, based on which we can take the relevant step towards development of the medical setup and treatment.

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Research on the Correlation of Serum PCT and Plasma GSN Levels with the Prognosis of Urosepsis Patients

Pakistan Journal of Medical Sciences ◽

10.12669/pjms.36.5.2143 ◽

2020 ◽

Vol 36 (5) ◽

Author(s):

Na Cui ◽

Zhanbiao Yu ◽

Zhi Chen ◽

Ning Chen

Keyword(s):

Poor Prognosis ◽

Original Work ◽

Protective Factor ◽

Good Prognosis ◽

Control Group ◽

Creative Commons ◽

The Poor ◽

Prognosis Group ◽

Good Prognosis Group ◽

Open Access Article

Objective: To explore the correlation of procalcitonin (PCT) and gelsolin (GSN) with the prognosis of urosepsis patients. Method: The data of 71 urosepsis patients from March 2015 to April 2019 who were admitted to and treated in Affiliated Hospital of Hebei University were analyzed and compared with those of 92 healthy persons. Serum PCT and plasma GSN levels at different times after treatment were detected. According to prognosis, patients were classified into the good prognosis group or the poor prognosis group. The serum PCT and plasma GSN levels of both groups were compared. Result: The serum PCT level of the urosepsis group on the 1st, 3rd, 5th and 7th days was obviously higher than that of the control group (P<0.05). The plasma GSN levels of the urosepsis group on the 1st, 3rd, 5th and 7th days were obviously lower than those of the control group (P<0.05).The serum PCT level of the poor prognosis group on the 1st, 3rd, 5th and 7th days was obviously higher than that of the good prognosis group (P<0.05). The plasma GSN level of the poor prognosis group on the 1st, 3rd, 5th and 7th days was obviously lower than that of the good prognosis group (P<0.05). PCT was an independent risk factor influencing the prognosis of urosepsis patients and that GSN was a protective factor (P<0.05). Conclusion: The serum PCT and plasma GSN levels can accurately predict the severity and prognosis of urosepsis patients and reflect the disease state of early urosepsis patients. High PCT levels and low GSN levels indicate poor prognosis, and clinicians should consider these values. doi: https://doi.org/10.12669/pjms.36.5.2143 How to cite this:Cui N, Yu Z, Chen Z, Chen N. Research on the Correlation of Serum PCT and Plasma GSN Levels with the Prognosis of Urosepsis Patients. Pak J Med Sci. 2020;36(5):---------. doi: https://doi.org/10.12669/pjms.36.5.2143 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Promoting Research Culture at Indus Health Network

Pakistan Journal of Medical Sciences ◽

10.12669/pjms.36.icon-suppl.1861 ◽

2019 ◽

Vol 36 (ICON-Suppl) ◽

Author(s):

Shaukat Ali Jawaid

Keyword(s):

Open Access ◽

Original Work ◽

Research Culture ◽

Health Network ◽

Creative Commons ◽

Special Supplement ◽

Open Access Article

doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1861 How to cite this:Jawaid SA. Promoting Research Culture at Indus Health Network. Pak J Med Sci. Special Supplement ICON 2020. 2020;36(1):S2. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1861 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Malaria and the climate in Karachi: An eight year review

Pakistan Journal of Medical Sciences ◽

10.12669/pjms.36.icon-suppl.1712 ◽

2019 ◽

Vol 36 (ICON-Suppl) ◽

Author(s):

Fivzia Herekar ◽

Sundus Iftikhar ◽

Ahsana Nazish ◽

Sabeen Rehman

Keyword(s):

Chart Review ◽

Climatic Factors ◽

Meteorological Data ◽

Climatic Variability ◽

Climate Variables ◽

Creative Commons ◽

Medical Chart Review ◽

Special Supplement ◽

The Relationship ◽

Open Access Article

Background and Objective: Malaria is an arthropod-borne infectious disease transmitted by the mosquito Anopheles and claims millions of lives globally every year. Reasons for failure to eradicate this disease are multifactorial. The seasonality of the malaria is principally determined by climatic factors conducive for breeding of the vector. We aimed to study the relationship between climatic variability and the seasonality of malaria over an eight-year duration. Methods: This was a retrospective medical chart review of 8,844 confirmed cases of malaria which presented to The Indus Hospital, Karachi from January 2008 to November 2015. Cases were plotted against meteorological data for Karachi to elicit monthly variation. Results: A secular incline and seasonality in malaria cases over the duration of 8 years was seen. More cases were reported in the summer, rainy season compared with the other three seasons in each year. There was significant association with specific climate variables such as temperature, moisture, and humidity. Conclusion: There is a marked seasonal variation of malaria in Karachi, influenced by various environmental factors. Identification of the ‘the concentrated period’ of malaria can be helpful for policymakers to deploy malaria control interventions. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1712 How to cite this:Herekar F, Iftikhar S, Nazish A, Rehman S. Malaria and the climate in Karachi: An eight year review. Pak J Med Sci. Special Supplement ICON 2020. 2020;36(1):S33-S37. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1712 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Study of etiological factors in unilateral maxillary chronic sinusitis

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20164806 ◽

2016 ◽

Vol 3 (1) ◽

pp. 88

Author(s):

D. Chandrika ◽

Anantharaju G. S.

Keyword(s):

Maxillary Sinusitis ◽

Clinical History ◽

Causative Factor ◽

Successful Outcome ◽

Dental Infection ◽

Deviated Nasal Septum ◽

Detailed Clinical History ◽

Chronic Maxillary Sinusitis ◽

Symptoms And Signs

Background: Chronic rhinosinusitis is an extremely prevalent disorder which has significant effect on quality of life of affected individual. Varied symptomatology and varied etiology of unilateral chronic maxillary rhinosinusitis requires a comprehensive approach by otorhinolaryngologist. The objectives of the study were to evaluate the causative factor of unilateral chronic maxillary sinusitis and to study clinical presentation of unilateral chronic maxillary sinusitis. Methods: 50 patients with symptoms and signs suggestive of unilateral chronic maxillary sinusitis were evaluated. All were subjected to detailed clinical history, ENT examination including complete orodental examination, diagnostic nasal endoscopy, intra oral peri apical radiographs, CT scan of para nasal sinuses. Results: Of total of 50 patients studied, gross deviated nasal septum (DNS) is commonest cause of chronic unilateral maxillary sinusitis followed by dental infection of upper premolars. Conclusions: This study was carried out with an effort to find out etiology of unilateral chronic maxillary sinusitis as identification of etiology will help in successful outcome of the treatment.

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