scholarly journals Η θεραπευτική σχέση στην ψυχοδυναμική συμβουλευτική και ψυχοθεραπεία: σύγχρονα κλινικά και εμπειρικά δεδομένα

2021 ◽  
Vol 26 (2) ◽  
pp. 32
Author(s):  
Vasiliki Yotsidi ◽  
Kalliopi Kounenou
Keyword(s):  
Therapeutic Relationship ◽  
Therapeutic Process ◽  
Clinical Work ◽  
Real Relationship ◽  
Dynamic Interactions ◽  
Therapeutic Value ◽  
Essential Components ◽  
Key Factor ◽  
Relationship Of

In the psychodynamic approach, the therapeutic relationship stands at the core of the therapeutic process and constitutes a key factor of the effectiveness of treatment. As such, highlighting the psychodynamic components associated with the therapeutic relationship can help reinforce the role of counseling and clinical psychologists, by offering a broader understanding of the various dynamic interactions in clinical work. Specifically, the present paper delineates particular aspects of the therapeutic relationship (e.g. therapeutic alliance, transference, countertransference, real relationship) that should be taken into account in counseling and psychotherapy as essential components of the therapeutic relationship. Current empirical data are presented to demonstrate the importance of these parameters for the therapeutic process and outcome. Emphasis is also placed on the conditions that need to be fulfilled in order to ensure a relationship of therapeutic value, such as the importance of the therapeutic framework and the role of the psychologists / psychotherapists in dealing with enactments. Finally, the benefits of using the potential of the therapeutic relationship in clinical practice are highlighted, for improving both someone’s relationship with oneself and with others.

The analyst as “boundary artist”: how does Winnicott’s theoretical and clinical work affect our perception of boundaries in the therapeutic relationship?

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Antoine Gordon
Keyword(s):  
Clinical Practice ◽  
Therapeutic Relationship ◽  
Therapeutic Process ◽  
Clinical Work ◽  
Transitional Space ◽  
Boundary Crossings ◽  
Relational Psychotherapy ◽  
Work Affect ◽  
Therapeutic Frame

Winnicott positioned his psychoanalytic style as distinct from Freudian and Kleinian theory, while his clinical practice was viewed by many as too enigmatic from which to establish a suitable theoretical framework. This article explores the role of boundaries within his practice and discusses whether he could be considered a “boundary artist” in the analyst’s chair. Winnicott’s underlying philosophy and clinical approaches are examined in relation to the analyst’s intrapsychic boundaries and the permeable border between the roles of analyst and analysand—particularly with regard to his notion of transitional space. Despite Winnicott exhibiting narcissistic tendencies that may have blurred the boundaries of the therapeutic frame, this critique demonstrates how he used his unique skill set to ensure boundary crossings could benefit the therapeutic process whilst avoiding harmful violations. Additionally, we will also consider the more problematic implications of Winnicott’s practice on modern relational psychotherapy.

scholarly journals HIF-1α promoted vasculogenic mimicry formation in lung adenocarcinoma through NRP1 upregulation in the hypoxic tumor microenvironment

2021 ◽  
Vol 12 (4) ◽  
Author(s):  
Ran Fu ◽  
Wenwen Du ◽  
Zongli Ding ◽  
Yi Wang ◽  
Yue Li ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Vasculogenic Mimicry ◽  
Tube Formation ◽  
Luciferase Reporter ◽  
Vimentin Expression ◽  
Cell Metastasis ◽  
Therapeutic Value ◽  
Key Factor ◽  
Important Form

AbstractNeovascularization is a key factor that contributes to tumor metastasis, and vasculogenic mimicry (VM) is an important form of neovascularization found in highly invasive tumors, including lung cancer. Despite the increasing number of studies focusing on VM, the mechanisms underlying VM formation remain unclear. Herein, our study explored the role of the HIF-1α/NRP1 axis in mediating lung adenocarcinoma metastasis and VM formation. HIF-1α, NRP1 expression, and VM in lung adenocarcinoma (LUAD) patient samples were examined by immunohistochemical staining. Quantitative real-time (qRT-PCR), western blot, transwell assay, wound healing assay, and tube formation assay were performed to verify the role of HIF-1α/NRP1 axis in LUAD metastasis and VM formation. ChIP and luciferase reporter assay were used to confirm whether NRP1 is a direct target of HIF-1α. In LUAD tissues, we confirmed a positive relationship between HIF-1α and NRP1 expression. Importantly, high HIF-1α and NRP1 expression and the presence of VM were correlated with poor prognosis. We also found that HIF-1α could induce LUAD cell migration, invasion, and VM formation by regulating NRP1. Moreover, we demonstrated that HIF-1α can directly bind to the NRP1 promoter located between −2009 and −2017 of the promoter. Mechanistically, MMP2, VE-cadherin, and Vimentin expression were affected. HIF-1α plays an important role in inducing lung adenocarcinoma cell metastasis and VM formation via upregulation of NRP1. This study highlights the potential therapeutic value of targeting NRP1 for suppressing lung adenocarcinoma metastasis and progression.

scholarly journals Transformational Changes and Sustainability: From the Perspective of Identity, Trust, Commitment, and Withdrawal

2019 ◽  
Vol 11 (11) ◽  
pp. 3159 ◽  
Author(s):  
Ambreen Malik ◽  
Muhammad Naseer Akhtar ◽  
Usman Talat ◽  
Kirk Chang
Keyword(s):  
Organizational Identification ◽  
Affective Commitment ◽  
Sustainable Change ◽  
Commitment To Change ◽  
Overall Justice ◽  
Withdrawal Behavior ◽  
Key Factor ◽  
Relationship Of ◽  
The Relationship

Drawing upon the psychology of sustainability, effective organizations can create a sense of belongingness for people, and successfully facilitate growth and development activities for both individuals as well as the organization itself. Extending the recommendations of Zappala, Toscano, and Licciardello, the current study considers a range of variables. The role of overall justice judgements and change favorableness are taken as predictors of affective commitment to change and exit-based withdrawal. The relationship is mediated by organizational identification and moderated by trust in organization. Overall, the results support the hypothesized relationships. Specifically, findings showed that both change favorableness and overall justice judgements are positively related to affective commitment to change and negatively related to exit-based withdrawal. Organizational identification mediates the relationships between overall justice judgements–affective commitment to change, change favorableness–affective commitment to change, and change favorableness–exit-based withdrawal, whilst trust in organizations moderated the direct relationship between overall justice judgements–affective commitment to change, and change favorableness–exit-based withdrawal. Furthermore, the indirect effect of trust in organizations positively moderated the relationship of overall justice judgements and change favorableness with affective commitment to change, and at the same time, it negatively moderated the relationship between change favorableness and exit-based withdrawal via organizational identification. Crucially, for practitioners, this brings trust of employees as a key factor that should be managed to ensure sustainable change. Both trust and identity appear important in improving commitment and lowering the exit-based withdrawal behavior of employees. Future recommendations, implications, and limitations are discussed.

scholarly journals Platelets as Key Factors in Hepatocellular Carcinoma

Cancers ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1022 ◽  
Author(s):  
Natasa Pavlovic ◽  
Bhavna Rani ◽  
Pär Gerwins ◽  
Femke Heindryckx
Keyword(s):  
Hepatocellular Carcinoma ◽  
Crucial Role ◽  
Primary Liver Cancer ◽  
Organ Damage ◽  
Potential Effect ◽  
Key Factors ◽  
Therapeutic Value ◽  
Key Factor ◽  
Proliferation And Invasion

Hepatocellular carcinoma (HCC) is a primary liver cancer that usually develops in the setting of chronic inflammation and liver damage. The hepatic microenvironment plays a crucial role in the disease development, as players such as hepatic stellate cells, resident liver macrophages (Kupffer cells), endothelial cells, extracellular matrix, and a variety of immune cells interact in highly complex and intertwined signaling pathways. A key factor in these cross-talks are platelets, whose role in cancer has gained growing evidence in recent years. Platelets have been reported to promote HCC cell proliferation and invasion, but their involvement goes beyond the direct effect on tumor cells, as they are known to play a role in pro-fibrinogenic signaling and the hepatic immune response, as well as in mediating interactions between these factors in the stroma. Anti-platelet therapy has been shown to ameliorate liver injury and improve the disease outcome. However, platelets have also been shown to play a crucial role in liver regeneration after organ damage. Therefore, the timing and microenvironmental setting need to be kept in mind when assessing the potential effect and therapeutic value of platelets in the disease progression, while further studies are needed for understanding the role of platelets in patients with HCC.

scholarly journals The flip side of collaborative alliance: a single-case study

2019 ◽  
Vol 22 (2) ◽  
Author(s):  
Francesca Locati ◽  
Pietro De Carli ◽  
Margherita Lang ◽  
Laura Parolin
Keyword(s):  
Therapeutic Relationship ◽  
Defense Mechanism ◽  
Single Case ◽  
Therapeutic Process ◽  
Single Case Study ◽  
Specific Factors ◽  
Definition Of ◽  
Relationship Of ◽  
Critical Aspects

The present single case study explored whether a positive collaboration may conceal some of the patient’s dysfunctional interpersonal schemas, hence reflecting a non-authentic collaboration. In particular, we reasoned that conceiving collaborations only as adaptive relations may prevent a comprehensive insight of the therapeutic relationship itself. To explore this possibility, we used an intersubjective approach that emphasizes the integration of specific and non-specific factors in an interdependent way. In particular, we assessed different constructs (i.e. therapeutic alliance, technical interventions, defense mechanism, therapeutic relationship) of the therapeutic process and combined them through statistical methods able to investigate the micro- and macro-analytic processes that define each interaction. Results of a single case study (Sara) showed that the collaborative functioning may hold back many critical aspects, that hardly conciliate with the classic positive definition of collaboration. These findings, therefore, indicate that Sara’s collaborative alliance works mainly as a pseudo-alliance.

The Therapeutic Relationship Reexamined: Clinical and Neurobiological Aspects of Empathic Attunement

2020 ◽  
Vol 48 (4) ◽  
pp. 392-406
Author(s):  
Myron L. Glucksman
Keyword(s):  
Clinical Improvement ◽  
Therapeutic Relationship ◽  
Mirror Neuron System ◽  
Mirror Neuron ◽  
Real Relationship ◽  
Neuron System ◽  
The Real ◽  
Developmental Experience ◽  
Clinical Illustration

This article explores salient aspects of the therapeutic relationship, including transference, nontransference (the “real” relationship), and empathic attunement. Evidence for a mirror neuron system mediating empathy in primates and humans is presented. A clinical illustration describes the interplay between impaired early attachment, developmental experience, psychopathology, mirror neuron dysfunction, and the role of empathic attunement toward facilitating clinical improvement.

Establishing a Group Educational Session for Hyperacusis Patients

2019 ◽  
Vol 28 (2) ◽  
pp. 245-250
Author(s):  
Ann E. Perreau ◽  
Richard S. Tyler ◽  
Patricia C. Mancini ◽  
Shelley Witt ◽  
Mohamed Salah Elgandy
Keyword(s):  
Therapeutic Process ◽  
Treatment Options ◽  
Clinical Group ◽  
Education Session ◽  
Group Approach ◽  
Treatment Protocols ◽  
Educational Session ◽  
Evidence Based Treatment ◽  
Relationship Of ◽  
The Relationship

Purpose Audiologists should be treating hyperacusis patients. However, it can be difficult to know where to begin because treatment protocols and evidence-based treatment studies are lacking. A good place to start in any tinnitus and hyperacusis clinic is to incorporate a group educational session. Method Here, we outline our approach to establishing a hyperacusis group educational session that includes specific aspects of getting to know each patient to best meet their needs, understanding the problems associated with hyperacusis, explaining the auditory system and the relationship of hyperacusis to hearing loss and tinnitus, describing the influence of hyperacusis on daily life, and introducing treatment options. Subjective responses from 11 adults with hyperacusis, who participated in a recent clinical group education session, were discussed to illustrate examples from actual patients. Conclusions Due to the devastating nature of hyperacusis, patients need to be reassured that they are not alone and that they can rely on audiologists to provide support and guidance. A group approach can facilitate the therapeutic process by connecting patients with others who are also affected by hyperacusis, and by educating patients and significant others on hyperacusis and its treatment options. Supplemental Material https://doi.org/10.23641/asha.8121197

Attachment Styles, Physical Proximity, and Relational Satisfaction

2014 ◽  
Vol 4 (2) ◽  
pp. 106-112
Author(s):  
Anita Shrivastava ◽  
Andrea Burianova
Keyword(s):  
Attachment Styles ◽  
Romantic Relationship ◽  
Distinct Type ◽  
Relational Satisfaction ◽  
Long Distance ◽  
Avoidant Attachment ◽  
Geographic Separation ◽  
Relationship Of ◽  
Attachment Dimensions

This study aimed to explore the relationships between attachment styles, proximity, and relational satisfaction. This was achieved by assessing a distinct type of long distance romantic relationship of flying crews, compared with proximal (non-flying crew) romantic relationships. The responses of 139 expatriate professionals revealed significant associations between proximity and anxious and avoidant attachment dimensions. The role of the avoidant dimension in comparison with that of the anxious dimension was found to be a significant predictor of relational satisfaction. This study contributes significantly toward addressing the role of proximity and attachment in relational satisfaction in a new context of geographic separation.

PERSEPSI PEMAHAMAN PERANAN AUDITOR, ETIKA AUDITOR DAN INDEPENDENSI AUDITOR INTERNAL DALAM MEWUJUDKAN GOOD UNIVERSITY GOVERNANCE DENGAN GAYA KEPEMIMPINAN SEBAGAI VARIABEL MODERASI

2019 ◽  
Vol 4 (1) ◽  
pp. 474
Author(s):  
Fipitriany Any
Keyword(s):  
Leadership Style ◽  
University Governance ◽  
Primary Data ◽  
Study Program ◽  
Internal Auditor ◽  
Internal Auditors ◽  
Analysis Models ◽  
Relationship Of ◽  
Role Ethics

ABSTRACT The purpose of this study is to examine and analyze the influence of the role, ethics, and independence of internal auditors in implementing good university governance (GUG) with leadership style as a moderation variable. Multiple linear regression and moderation regression analysis models are used to test the hypothesis. The primary data are obtained through questionnaires that are distributed to the respondents, namely the dean and head of study program at the UniversitasBinaDarma and UniversitasMuhammadiyahPalembang. The results of this study indicate that the instruments in each variable proved to be valid and reliable. Based on the results of hypothesis testing, it can be seen that simultaneously the variable of role, ethics, and independence of internal auditors have positively and significantly effect in implementing good university governance (GUG). These results provide justification or endorsement of the theoretical truths used as the theoretical references of Stewardship Theory and Attitude and Behavioral Theory. Based on the partial test, role of auditor does not significantly affect the variable of GUG, but ethics and independence variable are found to be significant in influencing GUG. The leadership style is negative and insignificant in moderating the role of internal auditors and GUC and also the independence of internal auditor and GUC. The leadership style is found to be positive and insignificant in moderating the relationship of internal auditors’ ethics and GUC.Keywords        Role, Ethics, Independence, Internal Auditor, Leadership Style, Good University Governance  ABSTRAK Tujuan dari penelitian ini adalah untuk menguji dan menganalisis pengaruh peran, etika, dan independensi auditor internal dalam menerapkan good university governance (GUG) dengan gaya kepemimpinan sebagai variabel moderasi. Model analisis regresi linier berganda dan regresi moderasi digunakan untuk menguji hipotesis. Data primer diperoleh melalui kuesioner yang dibagikan kepada responden, yaitu dekan dan ketua program studi di Universitas Bina Darma dan Universitas MuhammadiyahPalembang. Hasil penelitian ini menunjukkan bahwa instrumen dalam setiap variabel terbukti valid dan dapat diandalkan. Berdasarkan hasil pengujian hipotesis dapat dilihat bahwa secara simultan variabel peran, etika, dan independensi auditor internal berpengaruh positif dan signifikan dalam penerapan good university governance (GUG). Hasil ini memberikan pembenaran atau pengesahan kebenaran teoretis yang digunakan sebagai referensi teoretis dari Teori Penatalayanan dan Teori Sikap dan Perilaku. Berdasarkan uji parsial, peran auditor tidak secara signifikan mempengaruhi variabel GUG, tetapi variabel etika dan independensi ditemukan signifikan dalam mempengaruhi GUG. Gaya kepemimpinan negatif dan tidak signifikan dalam memoderasi peran auditor internal dan GUC dan juga independensi auditor internal dan GUC. Gaya kepemimpinan ditemukan menjadi positif dan tidak signifikan dalam memoderasi hubungan etika auditor internal dan GUC Kata Kunci            Peran, Etika, Independensi, Auditor Internal, Gaya Kepemimpinan, Tata Kelola Universitas

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