scholarly journals Massive Solitary Fibrous Tumor (SFT) of the infratemporal and pterygomaxillary fossa treated by combined endoscopic approach

F1000Research ◽  
2013 ◽  
Vol 2 ◽  
pp. 275
Author(s):  
François Cloutier ◽  
Geneviève Lapointe ◽  
Sylvie Nadeau
Keyword(s):  
Solitary Fibrous Tumor ◽  
Soft Tissues ◽  
Vascular Tumor ◽  
Large Mass ◽  
Minimal Invasive ◽  
Subtotal Resection ◽  
Postoperative Radiation Therapy ◽  
Rare Type ◽  
Fibrous Tumor ◽  
The Right

Solitary fibrous tumors (SFTs) were first described as spindle-cell tumors originating from the pleura. Until recently, there was some debate with regards to the name and origin of these tumors and the distinctions with the term haemangiopericytomas (HPCs), a rare type of vascular tumor.Morphological, immunohistochemical and clinical features of HPCs were not specific for one entity. With the exception of myopericytoma, infantile myofibromatosis and HPC-like lesions of the sinonasal tract showing myoid differentiation, all other HPC-like lesions are best considered as subtypes of SFT. Due to their mesenchymal origin, we are now aware that SFTs may involve several extrapleural sites including soft tissues or meninges. When SFTs involve the skull base and show malignant histological characteristics, they can be an important challenge for the surgical team.We report a case of a 54-year-old man complaining of poor vision and facial pain that had worsened over the last year. Computed tomography and magnetic resonance imaging indicated a large mass, involving the right infratemporal and pterygomaxillary fossa. A biopsy proved positive for a solitary fibrous tumor with malignant features. Surgery was performed using a combined approach of frontotemporal craniotomy and nasal endoscopy. The subtotal resection, conducted due to nodularity on the dura mater, was a success and was complemented by postoperative radiation therapy. Follow-up MRIs showed no recurrence of the tumor.To the authors’ knowledge, this is the first reported case of a massive SFT involving this region, treated with minimal invasive surgery without any facial osteotomies.

Solitary Fibrous Tumor of Nasal Cavity in Patient With Long-Standing History of Cocaine Inhalation

2004 ◽  
Vol 128 (1) ◽  
pp. e1-e4 ◽  
Author(s):  
Suman S. Chauhan ◽  
Jayshree Krishnan ◽  
Denis K. Heffner
Keyword(s):  
Nasal Cavity ◽  
Solitary Fibrous Tumor ◽  
Soft Tissues ◽  
S100 Protein ◽  
Large Mass ◽  
Left Nasal Cavity ◽  
Posterior Aspect ◽  
History Of ◽  
Fibrous Tumor ◽  
The Right

Abstract We report a solitary fibrous tumor in the nasal cavity of a 48-year-old woman who presented with a history of bilateral nasal obstruction and long-standing cocaine inhalation. Physical examination revealed a large mass involving the right nasal cavity and extending into the posterior aspect of the left nasal cavity. The computed tomography scan showed opacification of airways. During surgery, the mass was found to involve the entire nasal cavity, with extension to the right maxillary sinus, posterior nasal airways, and left nasal cavity. The mass was completely excised. Pathologic examination revealed a polypoid mass 3.7 × 3.0 × 1.2 cm. This tumor was composed of spindle cells that were cytologically bland in a background of ropey and nodular collagen, giving a “patternless” pattern. Immunohistochemically, the neoplastic cells stained for CD34 and vimentin but not for S100 protein, keratin, desmin, HMB-45, and c-Kit. This immunohistochemical pattern confirmed the diagnosis of solitary fibrous tumor. Although solitary fibrous tumors are usually found in the pleura, they can occur in various other locations, such as the orbit, nasal cavity, paranasal sinuses, mediastinum, breast, vagina, meninges, and soft tissues. This case is of interest because the tumor occurred in a patient with prolonged cocaine inhalation. Such an association has not been previously described. The exact causal relationship between cocaine inhalation and the tumor is not known.

scholarly journals Giant intracranial congenital hemangiopericytoma/solitary fibrous tumor: A case report and literature review

2019 ◽  
Vol 10 ◽  
pp. 75 ◽  
Author(s):  
Dimitrios Giakoumettis ◽  
Ioannis Nikas ◽  
Kalliopi Stefanaki ◽  
Antonis Kattamis ◽  
George Sfakianos ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Therapeutic Strategy ◽  
Good Prognosis ◽  
Subtotal Resection ◽  
Neurosurgical Department ◽  
Adult Type ◽  
Therapeutic Algorithm ◽  
Fibrous Tumor ◽  
The Right ◽  
Optimal Therapeutic Strategy

Background: Hemangiopericytoma and solitary fibrous tumor (HPC/SFT) are considered to be one category according to the WHO 2016 classification of central nervous system tumors. HPC/SFT are subdivided into infantile (congenital) and adult type. Both are extremely rare entities, with little knowledge about etiology, prognosis, and optimal therapeutic strategy. Case Description: A 10-day-old girl was referred to our neurosurgical department due to hypotonia, palsy of the right oculomotor nerve, and prominent frontal fontanel. Imaging studies revealed a large occupying mass in the right middle cerebral fossa and the suprasellar cisterns. Only a subtotal resection of the tumor was possible, and postoperatively, she underwent chemotherapy (CHx). After a 3-year follow-up, the girl has minimum neurologic signs and receives no medications, and she can walk when she is supported. Conclusion: Congenital HPC/SFT is considered to have a benign behavior with a good prognosis. Treatment with gross total resection, when it is feasible, is the key to a good prognosis and low rates of recurrence. However, there is no consensus on the therapeutic strategy of a HPC/SFT, which is difficult to be completely resected. Literature lacks a therapeutic algorithm for these tumors, and thus, more clinical studies are needed to reach a consensus.

scholarly journals Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report

2021 ◽  
Vol 13 (1) ◽  
pp. 259-266
Author(s):  
Ye-Tao Zhu ◽  
Yang Liu ◽  
Li-Gang Chen ◽  
Da-Ping Song
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Solitary Fibrous Tumor ◽  
Immunohistochemical Staining ◽  
Biological Behavior ◽  
Resonance Imaging ◽  
Solitary Fibrous Tumors ◽  
The Central Nervous System ◽  
Fibrous Tumor ◽  
The Right

Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case of malignant solitary fibrous tumor recurring 8 years after surgery in a 63-year-old male. Magnetic resonance imaging showed low to intermediate mixed signal intensity on T1W1. Immunohistochemical staining positivity for Vimentin, CD99, CD34 and Bcl-2, it is consistent with the immunohistochemical characteristics of solitary fibrous tumor. We resected the patient’s tumor, and the patient was followed up for 3 months with no signs of recurrence. Solitary fibrous tumors are very rare in the central nervous system. Immunohistochemical staining positivity for CD34 and Bcl-2 is strongly expressed in most solitary fibrous tumor. Surgical resection is the preferred treatment. Due to the small number of cases, the biological behavior and prognosis of this tumor need to be further explored.

Extrapleural Benign Solitary Fibrous Tumor in the Shoulder of a 9-Year-Old Girl: Case Report and Review of the Literature

2004 ◽  
Vol 7 (6) ◽  
pp. 653-660 ◽  
Author(s):  
Dinesh Rakheja ◽  
Kathleen S. Wilson ◽  
John J. Meehan ◽  
Roger A. Schultz ◽  
Gerhard E. Maale ◽  
...  
Keyword(s):  
Case Report ◽  
Solitary Fibrous Tumor ◽  
Cytogenetic Analysis ◽  
Young Age ◽  
Review Of The Literature ◽  
Unusual Location ◽  
Fibrous Tumor ◽  
The Right

We report a case of a benign solitary fibrous tumor that occurred in the right shoulder of a 9-year-old girl. This case is remarkable due to the unusual location of its occurrence and the young age of the patient. In addition, cytogenetic analysis revealed a karyotype unreported in this neoplasm: 46,XX,der(4)t(4;9)(q31.1;q34), del(9)(p22p24),der(9)t(4;9)(q31.1;q34)ins(9;?)(q34;?) (17 cells)/46,XX (3 cells).

scholarly journals Pediatric sellar solitary fibrous tumor/ hemangiopericytoma: A rare case report and review of the literature

2020 ◽  
Vol 11 ◽  
pp. 238
Author(s):  
Hammad Ghanchi ◽  
Tye Patchana ◽  
Eisha Christian ◽  
Chao Li ◽  
Mark Calayag
Keyword(s):  
Solitary Fibrous Tumor ◽  
Vision Loss ◽  
Adult Population ◽  
Tumor Resection ◽  
The Body ◽  
Subtotal Resection ◽  
Adjuvant Radiation ◽  
Sellar Region ◽  
First Case ◽  
Fibrous Tumor

Background: Solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) is a rare tumor which originates from the walls of capillaries and has historically been thought to be able to occur anywhere in the body that blood vessels are found. It is rarely found in the sellar region. Case Description: InS this report, we present the first case of this tumor occurring in the sellar region of a pediatric patient. This 12-year-old male presented with progressive vision loss which prompted surgical resection after a sellar lesion was discovered on imaging. The initial transsphenoidal approach resulted in subtotal resection and the patient experienced reoccurrence within 3 months. He underwent an orbitozygomatic craniotomy to achieve gross total tumor resection. Conclusion: We conducted a literature review of intracranial SFT/HPC in the pediatric population and found it to be an extremely rare occurrence, with <30 cases reported. The incidence of SFT/HPC occurring in the sellar region for any age group was also found to be a rare entity. Treatment recommendations for this tumor are also scarce, based on retrospective chart reviews from the adult population. The role for adjuvant radiation has mixed results.

A Highly Vascular Intracranial Solitary Fibrous Tumor Treated with Radiotherapy and Toremifene: Case Report

Neurosurgery ◽  
2005 ◽  
Vol 56 (6) ◽  
pp. E1378-E1378 ◽  
Author(s):  
Rebecca Gillian Macfarlane ◽  
Malcolm Galloway ◽  
Piers Nicholas Plowman ◽  
David Glyndor Treharne Thomas
Keyword(s):  
Solitary Fibrous Tumor ◽  
Vascular Tumor ◽  
Middle Meningeal Artery ◽  
Vascular Supply ◽  
Temporal Fossa ◽  
Dural Tail ◽  
History Of ◽  
Fibrous Tumor ◽  
Internal Carotid Arteries ◽  
Left Middle

Abstract OBJECTIVE AND IMPORTANCE: A case of an unusual intracranial solitary fibrous tumor with features of high vascularity and resultant difficulty at resection is presented. The use of surgery, radiotherapy, and toremifene has been successful with no recurrence after 18 months. CLINICAL PRESENTATION: A 33-year-old male patient presented with a 1-year history of loss of vision on the left side and a 3-month history of headache and lethargy. Magnetic resonance imaging showed a lobulated mass (7.6 × 4.5 cm) in the left temporal fossa and left parasellar, sellar, and suprasellar regions, with a “dural tail” more typical of meningioma. Vascular supply was from both the internal carotid arteries and the left middle meningeal artery, precluding embolization. INTERVENTION: At the time of the craniotomy, a highly vascular tumor was found. Intraoperative hemorrhage limited resection to 20% of the tumor. The histological diagnosis was of a solitary fibrous tumor with an unusually angiomatoid architecture. After the operation, radiotherapy and toremifene were administered. A dramatic reduction in the size of the tumor was seen with no recurrence to date. CONCLUSION: The use of surgery, radiotherapy, and toremifene in treatment of a vascular intracranial solitary fibrous tumor has been successful and warrants further research.

Solitary Fibrous Tumor of the Spinal Cord: Case Report and Review of the Literature

Neurosurgery ◽  
2004 ◽  
Vol 55 (2) ◽  
pp. E433-E438 ◽  
Author(s):  
Mitsuhiro Kawamura ◽  
Kazutaka Izawa ◽  
Noboru Hosono ◽  
Hiroshi Hirano
Keyword(s):  
Spinal Cord ◽  
Solitary Fibrous Tumor ◽  
Spinal Cord Tumor ◽  
Clinical Manifestations ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Spindle Cell Proliferation ◽  
Long Term Follow Up ◽  
Fibrous Tumor ◽  
The Right

Abstract OBJECTIVE AND IMPORTANCE: A solitary fibrous tumor (SFT) is a rare neoplasm of probable mesenchymal origin that was first reported in the pleura but can occur in different sites. Only six cases of SFT arising from the spinal cord have been reported. CLINICAL PRESENTATION: We report a case of primary SFT occurring in the thoracic spinal cord in a 64-year-old man with Brown-Séquard syndrome. Magnetic resonance imaging revealed an intradural mass at the level of T2–T3. INTERVENTION: Total T2–T3 laminectomies were performed. The tumor appeared to be adherent to the right lateral aspect of the cord but not attached to the meninges. On histological examination, the tumor exhibited spindle cell proliferation with abundant dense collagen but without a hemangiopericytomatous pattern. Immunohistochemically, the tumor cells were reactive with CD34 and vimentin only. CONCLUSION: We report a rare case of SFT occurring in the thoracic spinal cord. Histologically and immunohistochemically, we confirmed the diagnosis of SFT. Low signal intensity on T1- and T2-weighted images corresponded to the histological findings. When a spinal cord tumor exhibits a signal pattern similar to this, SFT should be included in the differential diagnosis. Because of the rarity of reports on this condition, the clinical manifestations and course of SFT of the spinal cord are unknown, and careful long-term follow-up is recommended.

scholarly journals A Hemiclamshell Incision for a Giant Solitary Fibrous Tumor of the Right Hemithorax

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Nilgün Kanlıoğlu Kuman ◽  
Serdar Şen ◽  
Salih Çokpınar ◽  
Emel Ceylan ◽  
Canten Tataroğlu ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Superior Vena ◽  
Vena Cava ◽  
Resected Specimen ◽  
Transthoracic Needle Biopsy ◽  
Mediastinal Shift ◽  
Giant Tumor ◽  
Magnetic Resonance Imaging Mri ◽  
Fibrous Tumor ◽  
The Right

A 41-year-old female was admitted with respiratory distress. Chest radiographs showed opacity in the right hemithorax with mediastinal shift. Computed tomography (CT) scan showed a pleural mass with a 22 cm diameter occupying the whole right hemithorax and causing atelectasis. Magnetic resonance imaging (MRI) showed lower position of the right hemidiaphragm and the liver. Superior vena cava and heart were shifted to left. Presence of infiltration to the adjacent tissues could not be clearly evaluated because of pressure effect. Transthoracic needle biopsy specimen was reported to be benign. Because of the size and location of the mass, a hemiclamshell incision was chosen, which allowed excellent visualization and complete dissection of the giant tumor. The histopathology of the resected specimen confirmed solitary fibrous tumor. The patient was stabilized by careful observation and treatment. No complication except pneumonia in the postoperative first month occurred during the 22-month follow-up period.

scholarly journals Hemorrhagic intramedullary solitary fibrous tumor of the conus medullaris: case report

2015 ◽  
Vol 23 (4) ◽  
pp. 438-443 ◽  
Author(s):  
Corey T. Walker ◽  
Chiazo S. Amene ◽  
Jeffrey S. Pannell ◽  
David R. Santiago-Dieppa ◽  
Robert C. Rennert ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Conus Medullaris ◽  
The Body ◽  
Pathological Examination ◽  
Spinal Tumors ◽  
Anatomical Location ◽  
Lower Extremity Weakness ◽  
Imaging Characteristics ◽  
Fibrous Tumor ◽  
The Right

The differential diagnosis of spinal tumors is guided by anatomical location and imaging characteristics. Diagnosis of rare tumors is made challenging by abnormal features. The authors present the case of a 47-year-old woman who presented with progressive subacute right lower-extremity weakness and numbness of the right thigh. Physical examination further revealed an extensor response to plantar reflex on the right and hyporeflexia of the right Achilles and patellar reflexes. Magnetic resonance imaging of the lumbar spine demonstrated an 8-mm intramedullary exophytic nodule protruding into a hematoma within the conus medullaris. Spinal angiography was performed to rule out an arteriovenous malformation, and resection with hematoma evacuation was completed. Pathological examination of the resected mass demonstrated a spindle cell neoplasm with dense bundles of collagen. Special immunostaining was performed and a diagnosis of solitary fibrous tumor (SFT) was made. SFTs are mesenchymally derived pleural neoplasms, which rarely present at other locations of the body, but have been increasingly described to occur as primary neoplasms of the spine and CNS. The authors believe that this case is unique in its rare location at the level of the conus, and also that this is the first report of a hemorrhagic SFT in the spine. Therefore, with this report the authors add to the literature the fact that this variant of an increasingly understood but heterogeneous tumor can occur, and therefore should be considered in the differential of clinically similar tumors.

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