scholarly journals Ambient and Indoor Air Pollution in Pregnancy and the risk of Low birth weight and Ensuing Effects in Infants (APPLE): A cohort study in Bangalore, South India

2020 ◽  
Vol 3 ◽  
pp. 133
Author(s):  
Prafulla Shriyan ◽  
Giridhara R Babu ◽  
Deepa Ravi ◽  
Yamuna Ana ◽  
Onno CP van Schayck ◽  
...  

Background: Exposure to air pollution (IAP) from the combustion of solid fuels is a significant cause of morbidity and mortality in developing countries. Pregnant women exposed to higher pollutant levels are at higher risk of delivering a low-birth-weight (LBW) baby. There is a lack of standardized data regarding the levels and types of specific pollutants and how they impact LBW. We aim to prospectively assess the association between ambient and indoor air pollution levels in pregnancy and low birth weight and understand the subsequent risk of adiposity in these infants. Methods: We will conduct a prospective cohort study of 516 pregnant women recruited before 18 weeks of gestation in the urban slums of Bangalore, who have voluntarily consented to participate. We will estimate the level of air pollutants including particulate matter (<10 μm, <2.5 μm) and carbon monoxide (CO) parts per million (ppm) levels in both indoor and ambient environment. The follow-up of the delivered children will be done at delivery until the infant is one year old. The association between pollutants and LBW will be evaluated using logistic regression adjusting for potential confounders.Further, we will explore the mediation role of LBW in the hypothesized causal chain of air pollution and adiposity. Nested within a large cohort titled "Maternal Antecedents of Adiposity and Studying the Transgenerational role of Hyperglycemia and Insulin (MAASTHI)", we can estimate the absolute risk of having low birth weight caused by air pollution and other variables. Discussion: Understanding the association between exposures to ambient and indoor air pollution and low birth weight is essential in India. LBW babies have a higher risk of developing obesity and Non-Communicable Diseases (NCDs) during adulthood. The results from this study can inform the efforts for controlling the air pollution-related chronic diseases in India.

2019 ◽  
Vol 3 ◽  
pp. 133
Author(s):  
Prafulla Shriyan ◽  
Giridhara R Babu ◽  
Deepa Ravi ◽  
Yamuna Ana ◽  
Onno CP van Schayck ◽  
...  

Background: Exposure to air pollution (IAP) from the combustion of solid fuels is a significant cause of morbidity and mortality in developing countries. Pregnant women exposed to higher pollutant levels are at higher risk of delivering a low-birth-weight (LBW) baby. There is a lack of standardized data regarding the levels and types of specific pollutants and how they impact LBW. We aim to prospectively assess the association between ambient and indoor air pollution levels in pregnancy and low birth weight and understand the subsequent risk of adiposity in these infants. Methods: We will conduct a prospective cohort study of 516 pregnant women recruited before 18 weeks of gestation in the urban slums of Bangalore, who have voluntarily consented to participate. We will estimate the level of air pollutants including coarse particulate matter 10 ug/m3 (PM10 ), fine particulate matter 2.5 ug/m3(PM2.5) and carbon monoxide (CO) parts per million (ppm) levels in both indoor and ambient environment. The follow-up of the delivered children will be done at delivery until the infant is two years old. The association between pollutants and LBW will be evaluated using logistic regression adjusting for potential confounders.Further, we will explore the mediation role of LBW in the hypothesized causal chain of air pollution and adiposity. Nested within a larger Maternal Antecedents of Adiposity and Studying the Transgenerational role of Hyperglycemia and Insulin (MAASTHI) cohort, we can estimate the absolute risk of having low birth weight caused by air pollution and other variables. Discussion: Understanding the association between exposures to ambient and indoor air pollution and low birth weight is essential in India. LBW babies have a higher risk of developing obesity and Non-Communicable Diseases (NCDs) during adulthood. The results from this study can inform the efforts for controlling the air pollution-related chronic diseases in India.


2018 ◽  
Vol 3 ◽  
pp. 133
Author(s):  
Prafulla Shriyan ◽  
Giridhara R Babu ◽  
Deepa Ravi ◽  
Yamuna Ana ◽  
Onno CP van Schayck ◽  
...  

Background: Exposure to air pollution (IAP) from the combustion of solid fuels is a significant cause of morbidity and mortality in developing countries. Pregnant women exposed to higher pollutant levels are at higher risk of delivering a low-birth-weight (LBW) baby. There is a lack of standardized data regarding the levels and types of specific pollutants and how they impact LBW. We aim to prospectively assess the association between ambient and indoor air pollution levels in pregnancy and low birth weight and understand the subsequent risk of adiposity in these infants. Methods: We will conduct a prospective cohort study of 516 pregnant women recruited before 18 weeks of gestation in the urban slums of Bangalore, who have voluntarily consented to participate. We will estimate the level of air pollutants including coarse particulate matter 10 ug/m3 (PM10 ), fine particulate matter 2.5 ug/m3(PM2.5) and carbon monoxide (CO) parts per million (ppm) levels in both indoor and ambient environment. The follow-up of the delivered children will be done at delivery until the infant is two years old. The association between pollutants and LBW will be evaluated using logistic regression adjusting for potential confounders.Further, we will explore the mediation role of LBW in the hypothesized causal chain of air pollution and adiposity. Nested within a larger Maternal Antecedents of Adiposity and Studying the Transgenerational role of Hyperglycemia and Insulin (MAASTHI) cohort, we can estimate the absolute risk of having low birth weight caused by air pollution and other variables. Discussion: Understanding the association between exposures to ambient and indoor air pollution and low birth weight is essential in India. LBW babies have a higher risk of developing obesity and Non-Communicable Diseases (NCDs) during adulthood. The results from this study can inform the efforts for controlling the air pollution-related chronic diseases in India.


2011 ◽  
Vol 139 (9-10) ◽  
pp. 651-656 ◽  
Author(s):  
Aleksandra Stankovic ◽  
Vladimir Mitrovic ◽  
Radomir Zivadinovic

Introduction. Epidemiological studies point out that exposure to air pollution during pregnancy is a risk for low birth weight. Objective. The aim of this study was to evaluate the effects of outdoor and indoor air pollution on the occurrence of low birth weight. Methods. The measurement of outdoor air pollutants, sulphur dioxide and black smoke was carried out daily at the Institute for Public Healthcare of Nis at two measuring locations, in Nis and Niska Banja during 2003. Subjects were 367 pregnant women, nonsmokers and who were not profesionally exposed to air pollution. Data on exposure to source of indoor air pollution (passive smoking and mode of heating) was determined on the basis of a questionnaire. Data on the characteristics of newborns were taken from the register of Obstetrics and Gyanecology Clinic of Nis. Results. We determined that exposure of pregnant women to outdoor air pollution and wood heating systems had influence on the occurence of low birth weight. Exposure to passive smoking had no influence on neonatal low birth weight. Conclusion. Exposure of pregnant women to outdoor and indoor air pollutants can have negative influence on the occurrence of low birth weight.


Epidemiology ◽  
2005 ◽  
Vol 16 (5) ◽  
pp. S86 ◽  
Author(s):  
A R. Siddiqui ◽  
J Peerson ◽  
K H. Brown ◽  
E B. Gold ◽  
K Lee ◽  
...  

2019 ◽  
Vol 10 (2) ◽  
pp. 93-100
Author(s):  
Dwi Septiawati ◽  
Ani Nidia Listianti

Adverse birth outcomes are determined by a complex combination of genetic, social, and environmental factors. Numerous studies have concluded an association exists between air pollution and low birth weight (LBW). This case-controlled study aimed to analyze the association by using 38 cases (mothers of LBW infants) and 40 controls (mothers of normal birth weight infants) in Seberang Ulu 1, Palembang City. Primary data related to indoor air pollution exposure during pregnancy was collected via structured interviews. The data was analyzed by performing chi-square and multiple logistic regressions within a risk factor model. Exposure to indoor air pollution during pregnancy was associated with the occurrence of LBW (chi-square test, p-value: 0.012, OR 3611 [95% CI 1.415 to 9.215]). No variables were found to have an interaction with the effects of indoor air pollution exposure during pregnancy and the occurrence of LBW. Exposure to indoor air pollution during pregnancy had the most significant impact on LBW occurrences after controlling for maternal age during pregnancy (multiple logistic regression, p-value: 0.019, OR 3.19 [95% CI 1, 21-8.406]). Keywords: Indoor air pollution, low birth weight, pregnancy,


2010 ◽  
Vol 32 (1) ◽  
pp. 70-81 ◽  
Author(s):  
D. P. Pope ◽  
V. Mishra ◽  
L. Thompson ◽  
A. R. Siddiqui ◽  
E. A. Rehfuess ◽  
...  

Epidemiology ◽  
2005 ◽  
Vol 16 (5) ◽  
pp. S100-S101 ◽  
Author(s):  
L Thompson ◽  
N Bruce ◽  
A Diaz ◽  
B Arana ◽  
R Klein ◽  
...  

2021 ◽  
Vol 12 ◽  
pp. 215013272110343
Author(s):  
Sewitemariam Desalegn Andarge ◽  
Abriham Sheferaw Areba ◽  
Robel Hussen Kabthymer ◽  
Miheret Tesfu Legesse ◽  
Girum Gebremeskel Kanno

Background Indoor air pollution from different fuel types has been linked with different adverse pregnancy outcomes. The study aimed to assess the link between indoor air pollution from different fuel types and anemia during pregnancy in Ethiopia. Method We have used the secondary data from the 2016 Ethiopian Demographic and Health Survey data. The anemia status of the pregnant women was the dichotomous outcome variable and the type of fuel used in the house was classified as high, medium, and low polluting fuels. Logistic regression was employed to determine the association between the exposure and outcome variables. Adjusted Odds Ratio was calculated at 95% Confidence Interval. Result The proportion of anemia in the low, medium, and high polluting fuel type users was 13.6%, 46%, 40.9% respectively. In the multivariable logistic regression analysis, the use of either kerosene or charcoal fuel types (AOR 4.6; 95% CI: 1.41-18.35) and being in the third trimester (AOR 1.72; 95% CI: 1.12-2.64) were significant factors associated with the anemia status of the pregnant women in Ethiopia. Conclusion According to our findings, the application of either kerosene or charcoal was associated with the anemia status during pregnancy in Ethiopia. An urgent intervention is needed to reduce the indoor air pollution that is associated with adverse pregnancy outcomes such as anemia.


Sign in / Sign up

Export Citation Format

Share Document