scholarly journals Rapid inactivation of SARS-CoV-2 by titanium dioxide surface coating

2021 ◽  
Vol 6 ◽  
pp. 56
Author(s):  
Petra Micochova ◽  
Ambika Chadha ◽  
Timi Hesseloj ◽  
Franca Fraternali ◽  
Jeremy J. Ramsden ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Control Measure ◽  
Infection Control Measure ◽  
Atomic Ratio ◽  
Health Care Facilities ◽  
Target Cells ◽  
Ceramic Tiles ◽  
Live Virus ◽  
Significant Difference ◽  
The Stability

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission occurs via airborne droplets and surface contamination. Titanium dioxide (TiO2) coating of surfaces is a promising infection control measure, though to date has not been tested against SARS-CoV-2. Methods: Virus stability was evaluated on TiO2- and TiO2–Ag (Ti:Ag atomic ratio 1:0.04)-coated 45 x 45 mm ceramic tiles. After coating the tiles were stored for 2–4 months before use. We tested the stability of both SARS-CoV-2 Spike pseudotyped virions based on a lentiviral system, as well as fully infectious SARS-CoV-2 virus. For the former, tile surfaces were inoculated with SARS-CoV-2 spike pseudotyped HIV-1 luciferase virus. At intervals virus was recovered from surfaces and target cells infected. For live virus,  after illuminating tiles for 0–300 min virus was recovered from surfaces followed by infection of Vero E6 cells. % of infected cells was determined by flow cytometry detecting SARS-CoV-2 nucleocapsid protein 24 h post-infection. Results: After 1 h illumination the pseudotyped viral titre was decreased by four orders of magnitude. There was no significant difference between the TiO2 and TiO2–Ag coatings. Light alone had no significant effect on viral viability. For live SARS-CoV-2, virus was already significantly inactivated on the TiO2 surfaces after 20 min illumination. After 5 h no detectable active virus remained. Significantly, SARS-CoV-2 on the untreated surface was still fully infectious at 5 h post-addition of virus. Overall, tiles coated with TiO2 120 days previously were able to inactivate SARS-CoV-2 under ambient indoor lighting with 87% reduction in titres at 1h and complete loss by 5h exposure. Conclusions: In the context of emerging viral variants with increased transmissibility, TiO2 coatings could be an important tool in containing SARS-CoV-2, particularly in health care facilities where nosocomial infection rates are high.

scholarly journals Rapid inactivation of SARS-CoV-2 by titanium dioxide surface coating

2021 ◽  
Vol 6 ◽  
pp. 56
Author(s):  
Petra Micochova ◽  
Ambika Chadha ◽  
Timi Hesseloj ◽  
Franca Fraternali ◽  
Jeremy J. Ramsden ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Control Measure ◽  
Infection Control Measure ◽  
Atomic Ratio ◽  
Health Care Facilities ◽  
Target Cells ◽  
Ceramic Tiles ◽  
Live Virus ◽  
Significant Difference ◽  
The Stability

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission occurs via airborne droplets and surface contamination. Titanium dioxide (TiO2) coating of surfaces is a promising infection control measure, though to date has not been tested against SARS-CoV-2. Methods: Virus stability was evaluated on TiO2- and TiO2–Ag (Ti:Ag atomic ratio 1:0.04)-coated 45 x 45 mm ceramic tiles. After coating the tiles were stored for 2–4 months before use. We tested the stability of both SARS-CoV-2 Spike pseudotyped virions based on a lentiviral system, as well as fully infectious SARS-CoV-2 virus. For the former, tile surfaces were inoculated with SARS-CoV-2 spike pseudotyped HIV-1 luciferase virus. At intervals virus was recovered from surfaces and target cells infected. For live virus,  after illuminating tiles for 0–300 min virus was recovered from surfaces followed by infection of Vero E6 cells. % of infected cells was determined by flow cytometry detecting SARS-CoV-2 nucleocapsid protein 24 h post-infection. Results: After 1 h illumination the pseudotyped viral titre was decreased by four orders of magnitude. There was no significant difference between the TiO2 and TiO2–Ag coatings. Light alone had no significant effect on viral viability. For live SARS-CoV-2, virus was already significantly inactivated on the TiO2 surfaces after 20 min illumination. After 5 h no detectable active virus remained. Significantly, SARS-CoV-2 on the untreated surface was still fully infectious at 5 h post-addition of virus. Overall, tiles coated with TiO2 120 days previously were able to inactivate SARS-CoV-2 under ambient indoor lighting with 87% reduction in titres at 1h and complete loss by 5h exposure. Conclusions: In the context of emerging viral variants with increased transmissibility, TiO2 coatings could be an important tool in containing SARS-CoV-2, particularly in health care facilities where nosocomial infection rates are high.

Stability of Ceramic Glazes Obtained by Valorification of Anorganic Pigments Extracted from Electroplating Sludge

2018 ◽  
Vol 69 (3) ◽  
pp. 571-574
Author(s):  
Mihaela Andreea Mitiu ◽  
Maria Iuliana Marcus ◽  
Maria Vlad ◽  
Cristina Mihaela Balaceanu
Keyword(s):  
Heavy Metals ◽  
Leaching Tests ◽  
Ceramic Tiles ◽  
Research Activity ◽  
Limit Values ◽  
Leaching Potential ◽  
International Standard ◽  
Ceramic Samples ◽  
Electroplating Sludge ◽  
The Stability

This paper presents the results of the research activity in order to etablish the stability and leaching potential of ceramic tiles which have been developed using glazes colored with pigments obtained by the extraction of chromium and iron metals from electroplating sludge. All these ceramic tiles contain various amounts of heavy metals in their glazes due to the pigments composition. The ceramic samples have been subjected to leaching tests in order to detect if various elements of relevance such as chromium, lead, cadmium, zinc or iron migrated to any great extent into test solutions. Leaching tests have been performed following the international standard SR ISO 10545-15 method for specific metals leaching into 4% acetic acid solutions at 220C after a 24h period and the international standard SR EN 12457/1-4 method with distilled water as leaching agent at LSR of 10 l/kg, for 24h period. Amounts of heavy metals have been negligible or non-detectable (iron) in the leaching solutions, being well below the limit values established by the legislation in force.

Stability and mutual impact of perception of parental pressure and infants' social support – A study based on the difference between employment status and household income

2021 ◽  
pp. 002072092199705
Author(s):  
Yong Wang
Keyword(s):  
Household Income ◽  
Employment Status ◽  
Working Mothers ◽  
Social Research ◽  
Research Report ◽  
Parental Pressure ◽  
Income Levels ◽  
Significant Difference ◽  
The Difference ◽  
The Stability

The purpose of this study is to explore the stability and interaction between parental pressure and social research report, as well as the role of employment status and family income levels in this process. This study used a special study on Korean children (PSKC) 2–4 waves. Use t-test, correlation and autoregressive cross-delay modeling to analyze the data. The main findings of this study are: First, over time, parental pressure and mother’s social research report are consistent. Secondly, the pressure of motherhood and childcare has an obvious lagging effect on upbringing, and vice versa. Third, there is no significant difference between working mothers and non-working mothers in terms of the stability of working parents' pressure, social research report and social research report for children's pressure channels. However, parental pressure can only predict the social research report of working mothers. Fourth, there is no significant difference between the stability and interaction of these two structures in household income levels. In short, the results show that, over time, parental pressure is consistent with mother’s social research report. The results also show that there is a significant cross-lag effect between the mothers’ perceptions of mutual pressure analysis. In the process from parental pressure to social research report, I found the difference between working and non-working mothers. The advantage of this study is that the expected longitudinal design was adopted during infancy and the priority between the two structures can be considered. The results of this study can be used as a source of intervention plans to help parents withstand severe parenting pressure and lack of social research report.

scholarly journals A titanium dioxide–carbon nanotube hybrid to simultaneously achieve the mechanical enhancement of natural rubber and its stability under extreme frictional conditions

2021 ◽  
Vol 2 (7) ◽  
pp. 2408-2418
Author(s):  
Le Wan ◽  
Cong Deng ◽  
Ze-Yong Zhao ◽  
Hai-Bo Zhao ◽  
Yu-Zhong Wang
Keyword(s):  
Titanium Dioxide ◽  
Carbon Nanotube ◽  
Natural Rubber ◽  
Titanium Oxide ◽  
The Stability

Titanium oxide-carbon nanotube hybrids may efficiently promote the stability of nature rubber under extreme frictional conditions.

The Preparedness of Primary Health Care Network in terms of Emergency Risk Communication: A Study in Iran

2021 ◽  
pp. 1-10
Author(s):  
Zeinab Bagheri ◽  
Tahereh Dehdari ◽  
Masoud Lotfizadeh
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Risk Communication ◽  
Health Care Facilities ◽  
Effective Response ◽  
Care Network ◽  
Primary Health ◽  
Significant Difference ◽  
Health Care Network ◽  
Control And Prevention

Abstract Objective: Emergency Risk Communication (ERC) is known as 1 of the important components of an effective response to public health emergencies. In this study, we aimed to investigate the preparedness of the Primary Health Care Network (PHCN) of Iran in terms of the ERC. Methods: This study was conducted in 136 Primary Health Care Facilities (PHCFs) affilated to Shahrekord University of Medical Sciences, Chaharmahal and Bakhtiari Province, Iran. Data in terms of ERC were collected using a checklist developed by the Center of Disease Control and Prevention (CDC). Results: The findings of the study revealed that 65.9% of the PHCFs had low preparedness in terms of the ERC, 33.3% had a moderate level and 0.8% had high preparedness in this regard. There was a significant difference between the level of ERC and the history of crisis in the past year, PHCF type, and the education level of the responsible employees in the crisis unit in the PHCF. Conclusions: The results showed that the PHCFs studied need to increase their capacity and capability in the field of ERC. Further efforts to provide ERC components may increase the preparedness of PHCN in Iran in terms of the ERC.

scholarly journals Efficacy of Selective Grinding Guided by an Occlusal Splint in Management of Myofascial Pain: A Prospective Clinical Trial

2017 ◽  
Vol 11 (1) ◽  
pp. 301-311
Author(s):  
Felipe J. Fernández-González ◽  
Jorge Cabero-López ◽  
Aritza Brizuela ◽  
Ivan Suazo ◽  
Esteban Pérez-Pevida ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Myofascial Pain ◽  
Vertical Displacement ◽  
Occlusal Splint ◽  
Significant Difference ◽  
Before And After ◽  
Skeletal Pattern ◽  
Condylar Position ◽  
The Stability ◽  
Facial Types

Background:For patients whose centric relation (CR) has not been considered at the start and during treatment, the task of achieving an occlusal scheme that works together with the temporomandibular joint, the muscles, and the structures of the stomatognathic apparatus becomes a major concern.Objective:This study aims to describe a reproducible, predictable and to date unreported procedure of selective grinding guided by an occlusal splint and to analyze condylar position (CP) based on the skeletal pattern.Methods:A total of 72 symptomatic patients (38 females and 34 males) were classified into three groups: hyperdivergent, intermediate and hypodivergent. CP was quantified by mounted casts on a measures condyle displacement (MCD) device. Helkimo index was also performed in order to assess the severity of the temporomandibular joint (TMJ) disorders attending to clinical dysfunction, occlusal state and anamnestic dysfunction. Once the stability had been obtained, the splint was progressively reduced until the maximum intercuspation (MIC) was achieved.Results:The vertical displacement was found to be significantly different between the hyperdivergent and other two groups (p<0.01). Comparisons of MCD analysis before and after the selective grinding procedure identified a statistically significant difference in the horizontal and vertical CP (p<0.01) between the different groups whereas the Helkimo Index showed a clear improvement of TMJ disorders.Conclusion:All facial types, specially the hyperdivergent face type, showed a reduction in condylar displacement (CD) and less craniomandibular symptoms using this procedure, making it an excellent technique for clinicians.

scholarly journals Thermal Properties and Non-Isothermal Crystallization Kinetics of Poly (δ-Valerolactone) and Poly (δ-Valerolactone)/Titanium Dioxide Nanocomposites

Crystals ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 452 ◽  
Author(s):  
Waseem Saeed ◽  
Abdel-Basit Al-Odayni ◽  
Abdulaziz Alghamdi ◽  
Ali Alrahlah ◽  
Taieb Aouak
Keyword(s):  
Titanium Dioxide ◽  
Crystallization Kinetics ◽  
Isothermal Crystallization ◽  
Three Dimensional ◽  
Degree Of Crystallinity ◽  
Simultaneous Occurrence ◽  
Scanning Calorimetry ◽  
Isothermal Crystallization Kinetics ◽  
The Stability ◽  
Kinetics Of

New poly (δ-valerolactone)/titanium dioxide (PDVL/TiO2) nanocomposites with different TiO2 nanoparticle loadings were prepared by the solvent-casting method and characterized by Fourier transform infra-red, differential scanning calorimetry, X-ray diffraction and scanning electron microscopy, and thermogravimetry analyses. The results obtained reveal good dispersion of TiO2 nanoparticles in the polymer matrix and non-formation of new crystalline structures indicating the stability of the crystallinity of TiO2 in the composite. A significant increase in the degree of crystallinity was observed with increasing TiO2 content. The non-isothermal crystallization kinetics of the PDVL/TiO2 system indicate that the crystallization process involves the simultaneous occurrence of two- and three-dimensional spherulitic growths. The thermal degradation analysis of this nanocomposite reveals a significant improvement in the thermal stability with increasing TiO2 loading.

scholarly journals Radiographic evaluation of the use of transverse traction device in vertebral arthrodesis for degenerative diseases

2014 ◽  
Vol 13 (1) ◽  
pp. 27-30
Author(s):  
Edgar Takao Utino ◽  
João Paulo Machado Bergamaschi ◽  
Luciano Antonio Nassar Pellegrino ◽  
Ricardo Shigueaki Galhego Umeta ◽  
Maria Fernanda Silber Caffaro ◽  
...  
Keyword(s):  
Evaluation Studies ◽  
Fusion Rate ◽  
Radiographic Evaluation ◽  
Pedicle Fixation ◽  
Degenerative Lumbar Diseases ◽  
Significant Difference ◽  
Traction Device ◽  
Consolidation Rate ◽  
The Stability

OBJECTIVE: Perform radiographic analysis of the use of Transverse Traction Device (DTT) with respect to fusion rate in patients submitted to vertebral arthrodesis for degenerative lumbar diseases. METHODS: We selected x-ray images on anteroposterior, lateral and oblique views and with maximum flexion and extension dynamics of 23 patients submitted to posterolateral arthrodesis of the lumbar spine with a minimum follow-up period of six months. The images were evaluated and classified by the Linovitz's system by two spine surgeons. RESULTS: We evaluated the radiographs of 23 patients after the minimum postoperative period of 6 months and of these, 11 have used DTT. With regard to the consolidation rate, seven patients (63.6%) in the group of DTT were classified as fusion as well as six patients (50%) who were not submitted to the treatment. There was no statistical difference between the groups regarding the consolidation rate. CONCLUSION: The use of transverse traction device in this study showed no significant difference in the rate of consolidation in radiographic evaluation. Studies on the effective participation of this device in the stability of pedicle fixation systems are still lacking in the literature.

scholarly journals Dynamics Analysis of a Mathematical Model for New Product Innovation Diffusion

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Chunru Li ◽  
Zujun Ma
Keyword(s):  
Mathematical Model ◽  
Time Delay ◽  
Media Coverage ◽  
New Product ◽  
Normal Form Theory ◽  
Center Manifold Theorem ◽  
Significant Difference ◽  
Form Theory ◽  
The Difference ◽  
The Stability

In this paper, a mathematical model with time-delay-related parameters and media coverage to describe the diffusion process of new products is proposed, in which the time-delay-related parameters denote the stage in which potential customers decide whether to adopt a new product. Then, the stability and the Hopf bifurcation of the proposed model are analyzed in detail. The center manifold theorem and the normal form theory are used to investigate the stability of the bifurcating periodic solution. Moreover, a numerical simulation is conducted to investigate the difference between the model with delay-dependent parameters and that with delay-independent parameters. The results show that there is significant difference between the two models.

scholarly journals The assessment of the stability of the corneal structure after LASIK correction of myopia by different optical zone diameters

2016 ◽  
Vol 73 (6) ◽  
pp. 572-576 ◽  
Author(s):  
Milorad Milivojevic ◽  
Vladimir Petrovic ◽  
Miroslav Vukosavljevic ◽  
Ivan Marjanovic ◽  
Mirko Resan
Keyword(s):  
Structural Parameters ◽  
Preoperative Assessment ◽  
Laser In Situ Keratomileusis ◽  
Group I ◽  
Significant Difference ◽  
Optical Zone ◽  
Corneal Structure ◽  
The Stability ◽  
Corneal Thinning

Background/Aim. Enlargement of optical zone (OZ) diameter during laser in situ keratomileusis (LASIK) correction of myopia postoperatively improves the optical outcome, however, it also leads to the increased stroma tissue consumption - progressive corneal thinning. The aim of this investigation was to present the possibility of safe OZ enlargement without impairing the structural stability of the cornea, while obtaining an improved optical outcome with LASIK treatment of shortsightedness. Methods. Preoperative assessment of the cornea structure and prediction of the ablated stroma tissue consumption was conducted in 37 patients (74 eyes) treated for shortsightedness by means of the LASIK method. With the eyes that, according to their cornea structure, had the capacity for OZ diameter enlargement of 0.5 mm, LASIK treatment was performed within the wider OZ diameter of 7.0 mm compared to the standard 6.5 mm. The following two groups were formed, depending on the diameter of the utilized OZ: the group I (the eyes treated with the OZ 6.5 mm, n = 37) and the group II (the eyes treated with the OZ 7.0 mm, n = 37). Results. No significant difference in the observed structural parameters of the cornea was detected between the groups of patients treated with different OZ diameters. The values of all the parameters were significantly bellow the threshold values for the development of postoperative ectasia. Conclusion. Diameter enlargement of the treated OZ, if there is a preoperative cornea capacity for such enlargement, will not impair the postoperative stability of the cornea structure, and will significantly improve the optical outcome.

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