TREATMENT OF CHRONIC SUPPURATIVE-CATARRHAL ENDOMETRITIS OF COWS PREPARATION MASTOMETRIN

2016 ◽  
Vol 1 (4) ◽  
pp. 83-85
Author(s):  
Минюк ◽  
Lyudmila Minyuk ◽  
Гришина ◽  
Darya Grishina
Keyword(s):  
Economic Evaluation ◽  
Cost Effectiveness ◽  
Treatment Regimen ◽  
Recovery Time ◽  
Research Evidence ◽  
Clinical Signs ◽  
Control Group ◽  
Chronic Endometritis ◽  
The Cost ◽  
Experimental Group

The aim of the work is to improve the effectiveness of treatment of cows with chronic endometritis using homeopathic Mastometrin drug. In this work given economic evaluation of the treatment of chronic purulent-catarrhal endometritis in cows using Mactometpin drug in a comparative perspective with the treatment regimen adopted in the economy. The material for the research were the cows of black-motley breed of dairy complex SEC Kuibyshev district Kinel Samara region. Before the start of the experimental work was performed obstetric clinical examination of the animals are not pregnant. Among the cows with chronic purulent-catarrhal endometritis it was formed on the basis of approximate analogs of two groups of cows (control, experimental) on 10 goals each. In the control group of cows treatment of chronic endometritis was performed under the scheme adopted in the farm. The animals of the experimental group were treated with the drug Mastometrin. To determine the cost-effectiveness of Mastometrin drug in the treatment of chronic endometritis, the duration of the analysis of the treatment was carried out in cows; treatment costs compared with the treatment regimen used in the farm. Based on what has been defined income per head. Research evidence that the use of the drug Mastometrin reduces the waning of clinical signs of chronic endometritis and recovery time than with the scheme of treatment used in the farm. Shown Mastometrin economic efficiency of the drug, whereby the drug Mastometrin proposed to use a dose of 5 ml intramuscularly at intervals of 12 hours daily for 7-14 days.

scholarly journals Myocardial contractility dysfunction in patients with chronic lymphocytic leukemia receiving chemotherapy and their treatment with enalapril

2020 ◽  
Vol 25 (2) ◽  
pp. 90-97 ◽  
Author(s):  
I. L. Davydkin ◽  
T. P. Kuzmina ◽  
I. A. Zolotovskaya ◽  
O. V. Tereshina ◽  
O. E. Danilova ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Treatment Regimen ◽  
Global Longitudinal Strain ◽  
Clinical Signs ◽  
Angiotensin Converting Enzyme Inhibitors ◽  
Lymphocytic Leukemia ◽  
Control Group ◽  
Early Assessment ◽  
Converting Enzyme Inhibitors ◽  
Experimental Group

Aim. To assess eft ventricular (LV) contractility dysfunction in patients with chronic lymphocytic leukemia (CLL) receiving chemotherapy with fludarabine, cyclophosphamide, and rituximab (FCR), and to determine the enalapril.effectiveness for their treatment.Material and methods. The study included 49 patients with newly diagnosed Binet stage B CLL in combination with class I-II stable angina, stage 1-2 hypertension and LV ejection fraction (EF) >50%. All subjects did not take angiotensin converting enzyme inhibitors (ACE inhibitors), had no clinical signs of heart failure (HF), and all had indications for FCR combination use before study start. Patients underwent two-dimensional echocardiography initially, before starting chemotherapy (period V1) and after three (84±5 days) (V2) and six (168±7 days) (V3) courses of chemo therapy (enalapril) was added to the treatment regimen in the experimental group.Results. After the third course of chemotherapy, a relative percentage decrease in global longitudinal strain (GLS) was noted in the experimental and control groups — by 16,16±0,80 and 16,2±0,79, respectively (p=0,764). These changes are considered a cardiotoxicity predictor. At the same time, LVEF values remained within the normal range: 63,4% [65; 68] in the experimental group and 63,9% [61,6; 67] in the control group (p=0,960). After the sixth course, LVEF values significantly differed (p=0,002): in the control group, five patients (21%) had cardiotoxicity; in experimental group, there were no patients with cardiotoxicity.Conclusion. A clinically significant decrease in GLS is a marker of subclinical LV contractile dysfunction and is a cardiotoxicity predictor in CLL patients receiving chemotherapy with FCR. The timely addition of enalapril to the treatment regimen can prevent cardiotoxicity in such patients. The need for early assessment of GLS during FCR courses for the detection and prevention of cardiotoxicity has been proved.

scholarly journals Cost-effectiveness of Growth Hormone and its Consumption Indications: A Systematic Review of Economic Evaluation Studies

2021 ◽  
Author(s):  
Mohsen Pakdaman ◽  
Fahimeh Golmakani ◽  
Hamid Reza Dehghan ◽  
Reza Valagohar ◽  
Akram Beik Yazdi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Growth Hormone ◽  
Economic Evaluation ◽  
Cost Effectiveness ◽  
Growth Hormone Deficiency ◽  
Short Stature ◽  
Hormone Deficiency ◽  
Control Group ◽  
Cost Efficacy ◽  
The Cost

Context: Growth hormone deficiency (GHD) is one of the main reasons for short stature in children, which can be treated by early diagnosis. Stature is an appropriate measure to assess a child’s overall growth and health, and one’s height can affect his psychosocial and social well-being. Human growth hormone (HGH) has extensive effects on biological processes as well as height. Due to the high cost of growth hormone (GH) drugs, in most countries GH is prescribed according to scientific indications. Methods: The present study was a systematic review, which examined PICOD- based case studies published from the beginning of 2002 to February 2019 on Web of Science, PubMed, Scopus, SID, Embase, and Magiran databases in the field of health technology assessment and the economic evaluation. According to the inclusion criteria, 11 relevant articles were selected in the present study. Results: The findings showed that GH therapy was effective in increasing patients’ quality of life, and that the growth rate of children treated with GH was more than 2.5 cm per year, in comparison to the control group. Furthermore, the results of the studies indicated the cost-effectiveness of GH since the cost of each centimeter height increase in children was on average US $20,000, and the incremental cost effectiveness ratio varies based on QALY’s criteria in studies for various indications (Turner syndrome, idiopathic short stature, growth hormone deficiency, Prader Willi syndrome, Infants small for gestational age (SGA), chronic renal failure (CRF) and (SHOX-D). The highest cost efficacy per QALY was for growth hormone deficiency (from £20,000 to £30,000), and the lowest cost efficacy is for Prader Willi (from £55,000 to £135,000). Conclusions: Studies showed that GH increases the height of the children treated with GHD, compared to the control children; hence, the use of growth hormone is recommended after doing the experiments for all children with GHD. This issue can be considered by health policy makers to implement in healthcare programs.

Effectiveness the use of additive MEGA-VIT in the ration of mares of Shetland pony breed

2020 ◽  
pp. 60-67
Author(s):  
G. Uskov ◽  
A. Tsopanova ◽  
T. Perezhogina
Keyword(s):  
Physiological State ◽  
Mineral Elements ◽  
Positive Influence ◽  
Control Group ◽  
Physiological Indicators ◽  
Mineral Additive ◽  
Nutritional Needs ◽  
Young Horses ◽  
The Cost ◽  
Experimental Group

Complete feeding of ponies is provided on the basis of data on their nutritional needs depending on age, sex, physiological state and level of productivity (the amount of milk produced and the intensity of growth of young animals). Ponies are sensitive to a lack of vitamins and mineral elements in the feed. When there is a sufficient amount of organic and mineral substances, but a lack or absence of vitamins, horses and ponies have impaired metabolism. The purpose of this work is to study the effectiveness of the use of vitamin and mineral additive MEGA-VIT in the rations of pregnant and lactating mares of Shetland pony breed. It has been found during of the researches that the vitamin and mineral additive MEGA-VIT had a positive influence on the productive and physiological indicators of animals. The cost of spent feed for the entire period of experiment in the control group was 50,6 thousand rubles, and in the experimental group it was 11,8 thousand rubles more or 23,5 %. Revenue from the sale of young horses of the control group amounted to 400 thousand rubles, and experimental group – 440 thousand rubles, this is by 40 thousand rubles more than in control group. This led to the increase in profit in the experimental group of mares by 28,1 thousand rubles and accordingly the level of profitability by 3,2 %. It has been recommended on the results have been obtained on the base of researches to include 30 g/head/day in the rations of mares of Shetland pony breed during pregnancy, and 50 g/head/day during lactation.

INFLUENCE OF STOCK HOUSE LIGHT ON DAIRY PRODUCTIVITY OF COWS

2020 ◽  
Keyword(s):  
Blood Serum ◽  
Physiological State ◽  
Light Level ◽  
Inorganic Phosphorus ◽  
Control Group ◽  
Hemoglobin Content ◽  
Milk Productivity ◽  
Reproductive Ability ◽  
The Cost ◽  
Experimental Group

The article is devoted to the solution of an urgent problem- influence of different lighting modes on the dairy productivity of cows. 2 groups of cows with 20 heads each were formed. In control group, light in the cowshed was 50-75 Lux for a light period of 7.5 h in January to 16.5 h in June, and in experimental group - 150-200 Lux and 16 h, respectively. It was found that the intensity and duration of illumination affects physiological state, reproductive ability and milk productivity of cows. In the experimental group of cows, compared with the control group, hemoglobin content in blood increased by 4.6% (P < 0.01), red blood cells - by 20.6% (P < 0.05), total protein - by 11.2% (P < 0.001), glucose - by 39.1% (P < 0.05). There was a tendency to increase the total calcium and inorganic phosphorus in blood serum of cows of the experimental group. The level of alkaline phosphatase in blood serum of cows in the control group was 71.5% (P < 0.01) higher than that of cows in the experimental group. Milk yield per 1 cow in the experimental cowshed was 433 kg more than in the control. The cost of 1 kg of milk in the experimental group was 0.94 rubles lower, and the profitability of milk production and sales is 9.42% higher than in the control group. To increase the milk productivity of cows, it is recommended to increase light level in barns for tethered keeping to 150-200 Lux, with the duration of lighting in the winter and transition periods of year up to 16 hours per day.

scholarly journals Cost-Effectiveness of an Exercise Programme that Provided Group or Individual Training to Reduce the Fall Risk in Healthy Community-Dwelling People Aged 65–80: A Secondary Data Analysis

Healthcare ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 714
Author(s):  
Isaac Aranda-Reneo ◽  
Laura Albornos-Muñoz ◽  
Manuel Rich-Ruiz ◽  
María Ángeles Cidoncha-Moreno ◽  
Ángeles Pastor-López ◽  
...  
Keyword(s):  
Economic Evaluation ◽  
Cost Effectiveness ◽  
Older People ◽  
Incremental Cost ◽  
Fall Risk ◽  
Community Dwelling ◽  
Effective Measure ◽  
The Individual ◽  
The Cost ◽  
Individual Training

Research has demonstrated that some exercise programs are effective for reducing fall rates in community-dwelling older people; however, the literature is limited in providing clear recommendations of individual or group training as a result of economic evaluation. The objective of this study was to assess the cost-effectiveness of the Otago Exercise Program (OEP) for reducing the fall risk in healthy, non-institutionalized older people. An economic evaluation of a multicenter, blinded, randomized, non-inferiority clinical trial was performed on 498 patients aged over 65 in primary care. Participants were randomly allocated to the treatment or control arms, and group or individual training. The program was delivered in primary healthcare settings and comprised five initial sessions, ongoing encouragement and support to exercise at home, and a reinforcement session after six months. Our hypothesis was that the patients who received the intervention would achieve better health outcomes and therefore need lower healthcare resources during the follow-up, thus, lower healthcare costs. The primary outcome was the incremental cost-effectiveness ratio, which used the timed up and go test results as an effective measure for preventing falls. The secondary outcomes included differently validated tools that assessed the fall risk. The cost per patient was USD 51.28 lower for the group than the individual sessions in the control group, and the fall risk was 10% lower when exercises had a group delivery. The OEP program delivered in a group manner was superior to the individual method. We observed slight differences in the incremental cost estimations when using different tools to assess the risk of fall, but all of them indicated the dominance of the intervention group. The OEP group sessions were more cost-effective than the individual sessions, and the fall risk was 10% lower.

In-line filtration reduced phlebitis associated with peripheral venous cannulation: Focus on cost-effectiveness and patients’ perspectives

2019 ◽  
Vol 21 (2) ◽  
pp. 154-160
Author(s):  
Gianluca Villa ◽  
Rosa Giua ◽  
Timothy Amass ◽  
Lorenzo Tofani ◽  
Cosimo Chelazzi ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Vascular Access ◽  
Cost Effective ◽  
Causative Factor ◽  
Control Group ◽  
Previous Trial ◽  
Venous Cannulation ◽  
Group A ◽  
The Cost ◽  
And Control

Background: In a previous trial, in-line filtration significantly prevented postoperative phlebitis associated with short peripheral venous cannulation. This study aims to describe the cost-effectiveness of in-line filtration in reducing phlebitis and examine patients’ perception of in-hospital vascular access management with and without in-line filtration. Methods: We analysed costs associated with in-line filtration: these data were prospectively recorded during the previous trial. Furthermore, we performed a follow-up for all the 268 patients enrolled in this trial. Among these, 213 patients responded and completed 6 months after hospital discharge questionnaires evaluating the perception of and satisfaction with the management of their vascular access. Results: In-line filtration group required 95.60€ more than the no-filtration group (a mean of € 0.71/patient). In terms of satisfaction with the perioperative management of their short peripheral venous cannulation, 110 (82%) and 103 (76.9%) patients, respectively, for in-line filtration and control group, completed this survey. Within in-line filtration group, 97.3% of patients were satisfied/strongly satisfied; if compared with previous experiences on short peripheral venous cannulation, 11% of them recognised in-line filtration as a relevant causative factor in determining their satisfaction. Among patients within the control group, 93.2% were satisfied/strongly satisfied, although up to 30% of them had experienced postoperative phlebitis. At the qualitative interview, they recognised no difference than previous experiences on short peripheral venous cannulation, and mentioned postoperative phlebitis as a common event that ‘normally occurs’ during a hospital stay. Conclusion: In-line filtration is cost-effective in preventing postoperative phlebitis, and it seems to contribute to increasing patient satisfaction and reducing short peripheral venous cannulation–related discomfort

СOMPLEX TREATMENT OF CATTLE WITH PURULENT CONJUNCTIVO-KERATITES

2021 ◽  
Vol 57 (1) ◽  
pp. 8-12
Author(s):  
M.V. Bizunova ◽  
A.V. Bizunov ◽  
N.G. Khomchenko
Keyword(s):  
Cost Effectiveness ◽  
Recovery Time ◽  
Intramuscular Administration ◽  
Complex Therapy ◽  
The Cost

The application of a nonwoven nanomaterial with tylosin and propolis 0.5×1 cm in size into the conjunctival sac once every three days in combination with the intramuscular administration of catosal at a dose of 10 ml within 5 successive days of a complex therapy improves recovery time in cattle with purulent conjunctival keratites and increases the cost-effectiveness of treatment.

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