Forestomach developmental failure in an 11-month-old Japanese Black steer          with severely retarded growth and chronic ruminal tympany

We report a case of a neuroendocrine carcinoma arising in a wound of the postoperative maxillary sinus that was difficult to distinguish from a postoperative maxillary cyst. The patient was a 65-year-old Japanese woman who complained of left exophthalmos with cheek swelling and eye movement disorders. In past history, she had, 40 years previously undergone operation on the bilateral maxillary sinus by Caldwell-Luc’s method. In a preoperative computed tomography, a mass occupied the left maxillary sinus showing irregular densities with destruction of the posterior bone walls and invasion into the left orbital. Both TI and T2 weighted magnetic resonance imaging showed low intensities and unevenness in the mass. We performed a biopsy of the maxillary tumor according to Caldwell-Luc’s method. Histological examination diagnosed neuroendocrine carcinoma. Radiation therapy (total 66Gy) resulted in partial response for this tumor. However, sinonasal neuroendocrine carcinoma has been identified as highly aggressive, with a high probability of recurrence and metastasis.

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Severe infection including disseminated herpes zoster triggered by subclinical Cushing’s disease: a case report

BMC Endocrine Disorders ◽

10.1186/s12902-021-00757-y ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Yuki Yamauchi ◽

Hiraku Kameda ◽

Kazuno Omori ◽

Michio Tani ◽

Kyu Yong Cho ◽

...

Keyword(s):

Herpes Zoster ◽

Cushing’S Disease ◽

Cardiopulmonary Arrest ◽

Severe Infection ◽

Japanese Woman ◽

The Body ◽

Cushing's Disease ◽

Old Japanese ◽

Subclinical Cushing’S Disease ◽

Physical Features

Abstract Background Subclinical Cushing’s disease (SCD) is defined by corticotroph adenoma-induced mild hypercortisolism without typical physical features of Cushing’s disease. Infection is an important complication associated with mortality in Cushing’s disease, while no reports on infection in SCD are available. To make clinicians aware of the risk of infection in SCD, we report a case of SCD with disseminated herpes zoster (DHZ) with the mortal outcome. Case presentation An 83-year-old Japanese woman was diagnosed with SCD, treated with cabergoline in the outpatient. She was hospitalized for acute pyelonephritis, and her fever gradually resolved with antibiotics. However, herpes zoster appeared on her chest, and the eruptions rapidly spread over the body. She suddenly went into cardiopulmonary arrest and died. Autopsy demonstrated adrenocorticotropic hormone-positive pituitary adenoma, renal abscess, and DHZ. Conclusions As immunosuppression caused by SCD may be one of the triggers of severe infection, the patients with SCD should be assessed not only for the metabolic but also for the immunodeficient status.

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A Case Report of Tongue Lymphoepithelial Carcinoma with a Histological Diagnostic Dilemma

Diagnostics ◽

10.3390/diagnostics11061039 ◽

2021 ◽

Vol 11 (6) ◽

pp. 1039

Author(s):

Daisuke Takeda ◽

Manabu Shigeoka ◽

Tenyu Sugano ◽

Nanae Yatagai ◽

Takumi Hasegawa ◽

...

Keyword(s):

Histological Finding ◽

Atypical Epithelium ◽

Diagnostic Dilemma ◽

Barr Virus ◽

Japanese Female ◽

Old Japanese ◽

Neoplastic Change ◽

Diagnostic Difficulties ◽

Epstein Barr ◽

Characteristic Features

Most head and neck lymphoepithelial carcinomas (LECs) arise in the nasopharynx and harbor Epstein–Barr virus (EBV). LEC is also a rare subtype of the oral squamous cell carcinoma (SCC). Morphologically, LEC is defined as resembling non-keratinizing nasopharyngeal carcinoma, undifferentiated subtype. The histological features and pathogenesis of oral LEC are not established. We describe a case of tongue LEC with histopathological diagnostic difficulties. A 72-year-old Japanese female presented with a whitish change on her left-side tongue. The diagnosis was atypical epithelium; neoplastic change could not be ruled out by a biopsy. Although the lesion was monitored at our hospital per her request, invasive carcinoma was detected 11 months later. Microscopically, conventional SCC was observed with the characteristic features as LEC confined to the deep part of the lesion. We briefly discuss this unusual histological finding and make a novel proposal for distinguishing oral LEC from LECs in other regions based on these histological findings.

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Septic shock due to Yersinia pseudotuberculosis infection in an adult immunocompetent patient: a case report and literature review

BMC Infectious Diseases ◽

10.1186/s12879-020-05733-w ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Takehiro Hashimoto ◽

Ryuichi Takenaka ◽

Haruka Fukuda ◽

Kazuhiko Hashinaga ◽

Shin-ichi Nureki ◽

...

Keyword(s):

Septic Shock ◽

Therapeutic Strategy ◽

Yersinia Pseudotuberculosis ◽

Immunocompromised Host ◽

Immunocompetent Patient ◽

Case Presentation ◽

Gram Negative ◽

Old Japanese ◽

The Right ◽

Immunocompetent Patients

Abstract Background Yersinia pseudotuberculosis infection can occur in an immunocompromised host. Although rare, bacteremia due to Y. pseudotuberculosis may also occur in immunocompetent hosts. The prognosis and therapeutic strategy, especially for immunocompetent patients with Y. pseudotuberculosis bacteremia, however, remains unknown. Case presentation A 38-year-old Japanese man with a mood disorder presented to our hospital with fever and diarrhea. Chest computed tomography revealed consolidation in the right upper lobe with air bronchograms. He was diagnosed with pneumonia, and treatment with intravenous ceftriaxone and azithromycin was initiated. The ceftriaxone was replaced with doripenem and the azithromycin was discontinued following the detection of Gram-negative rod bacteria in 2 sets of blood culture tests. The isolated Gram-negative rod bacteria were confirmed to be Y. pseudotuberculosis. Thereafter, he developed septic shock. Doripenem was switched to cefmetazole, which was continued for 14 days. He recovered without relapse. Conclusions We herein report a case of septic shock due to Y. pseudotuberculosis infection in an adult immunocompetent patient. The appropriate microorganism tests and antibiotic therapy are necessary to treat patients with Y. pseudotuberculosis bacteremia.

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Acid-fast bacilli smear test of a blood culture sample for the diagnosis of disseminated Mycobacterium genavense infection: A case report

International Journal of STD & AIDS ◽

10.1177/0956462420972224 ◽

2021 ◽

Vol 32 (5) ◽

pp. 483-485

Author(s):

Yo Murata ◽

Nobuaki Mori ◽

Narito Kagawa ◽

Kentaro Okuma ◽

Shinji Yoshida ◽

...

Keyword(s):

Blood Culture ◽

Culture Conditions ◽

Nontuberculous Mycobacterium ◽

Sequencing Analysis ◽

Culture Methods ◽

Smear Test ◽

Acid Fast Bacilli ◽

Mycobacterium Genavense ◽

Old Japanese ◽

Immunosuppressed Patients

Mycobacterium genavense, a nontuberculous Mycobacterium, is found in immunosuppressed patients, particularly in those with HIV. Mycobacterium genavense incubation under standard culture conditions is difficult, and its identification is challenging using routine culture methods. Herein, we report the case of a 40-year-old Japanese man with HIV presenting with disseminated M. genavense infection. An analysis using an automated blood culture system did not show positive signals during 6 weeks of incubation. However, an acid-fast bacilli smear of his blood sample was positive for the bacterium. Mycobacterium genavense was identified using sequencing analysis, targeting the heat shock protein 65 gene. The patient recovered from the infection, following antibiotic therapy for 18 months. Under suspicion of disseminated M. genavense infection and the absence of bacterial growth in blood culture samples, an acid-fast bacilli smear test of the sample may be useful for timely diagnosis.

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Dissimilarity of barley powdery mildew resistances Lomerit and Heils Hanna

Czech Journal of Genetics and Plant Breeding ◽

10.17221/45/2011-cjgpb ◽

2011 ◽

Vol 47 (No. 3) ◽

pp. 95-100 ◽

Cited By ~ 10

Author(s):

A. Dreiseitl

Keyword(s):

Powdery Mildew ◽

Agricultural Research ◽

Blumeria Graminis ◽

The Other ◽

Japanese Isolate ◽

Agricultural Research Institute ◽

Reaction Type ◽

Barley Cultivars ◽

Barley Powdery Mildew ◽

Old Japanese

  The resistance Heils Hanna (HH) was postulated in several tens of 471 previously tested winter barley cultivars. In this paper, new tests on 29 of these cultivars are reported. Thirty-two reference isolates of Blumeria graminis f.sp. hordei held in the pathogen genebank at the Agricultural Research Institute in Kromeriz, Ltd. including a Japanese isolate and five Israeli isolates were used for response tests. However, the resistance HH conferred by the gene Mla8 and herein characterised by reaction type 0 to an old Japanese isolate known as Race I was now postulated only in four cultivars. In the other 25 cultivars another resistance, characterised by reaction type 0 to Race I and also to two Israeli isolates, was detected. In addition to the two mentioned resistances, eight known (Bw, Dr2, Ha, IM9, Ln, Lv, Ra and Sp) resistances were found in the set examined. Lomerit was the only registered cultivar tested here in which the newly detected resistance was present alone, therefore, it is recommended that this resistance be designated Lo.

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Protein C Gene Mutation in an Older Adult Patient with Clostridium perfringens Septicemia-Related Visceral Vein Thrombosis

TH Open ◽

10.1055/s-0041-1728664 ◽

2021 ◽

Vol 05 (02) ◽

pp. e171-e173

Author(s):

Kiyoko Kanosue ◽

Satomi Nagaya ◽

Eriko Morishita ◽

Masayoshi Yamanishi ◽

Shinsaku Imashuku

Keyword(s):

Gene Mutation ◽

Clostridium Perfringens ◽

Protein C ◽

Later Life ◽

Heterozygous Mutation ◽

Protein C Deficiency ◽

Vein Thrombosis ◽

Thrombosis Risk ◽

Japanese Male ◽

Old Japanese

AbstractA 78-year-old Japanese male with Clostridium perfringens septicemia and cholecystitis was found to have thrombosis in the left branch of intrahepatic portal vein as well as superior mesenteric vein. Visceral vein thrombosis (VVT) in this case was associated with protein C deficiency, due to a heterozygous mutation, p. Arg185Met. Our experience emphasizes that VVT, or other thromboembolic events, may occur in later life, triggered by environmental thrombosis risk factors, together with underlying hereditary protein C gene mutation.

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Conservatively Treated Femoral Intertrochanteric Fracture With Early Asymptomatic Novel Coronavirus Disease 2019 (COVID-19): A Case Report

Geriatric Orthopaedic Surgery & Rehabilitation ◽

10.1177/2151459320969380 ◽

2020 ◽

Vol 11 ◽

pp. 215145932096938

Author(s):

Yuki Suzuki ◽

Toshihiko Kasashima ◽

Kazutoshi Hontani ◽

Yasuhiro Yamamoto ◽

Kanako Ito ◽

...

Keyword(s):

Intertrochanteric Fracture ◽

Screening Method ◽

Oxygen Demand ◽

Japanese Woman ◽

Trauma Patients ◽

Lung Field ◽

Old Japanese ◽

Femoral Intertrochanteric Fracture ◽

Novel Coronavirus ◽

The Right

Introduction: The ongoing outbreak of novel coronavirus disease 2019 (COVID-19) is a worldwide problem. Although diagnosing COVID-19 in fracture patients is important for selecting treatment, diagnosing early asymptomatic COVID-19 is difficult. We describe herein a rare case of femoral intertrochanteric fracture concomitant with early asymptomatic novel COVID-19. Case presentation: An 87-year-old Japanese woman was transferred to our emergency room with a right hip pain after she fell. She had no fever, fatigue, or respiratory symptoms on admission and within the 14 days before presenting to our hospital, and no specific shadow was detected in chest X-ray. However, chest computed tomography (CT) was performed considering COVID-19 pandemic, and showed ground-glass opacities with consolidation in the dorsal segment of the right lower lung field. Then, qualitative real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) was carried out and turned out to be positive. She was diagnosed right femoral intertrochanteric fracture with concomitant COVID-19 infection. Conservative treatment was applied to the fracture due to infection. After admission, fever and oxygen demand occurred but she recovered from COVID-19. Throughout the treatment period, no cross-infection from the patient was identified in our hospital. Conclusion: This case highlights the importance of considering chest CT as an effective screening method for infection on hospital admission in COVID-19-affected areas, especially in trauma patients with early asymptomatic novel COVID-19.

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The Temporomandibular Joint in a Rheumatoid Arthritis Patient after Orthodontic Treatment

The Angle Orthodontist ◽

10.2319/040708-201.1 ◽

2009 ◽

Vol 79 (4) ◽

pp. 804-811 ◽

Cited By ~ 9

Author(s):

Kenichi Sasaguri ◽

Rika Ishizaki-Takeuchi ◽

Sakurako Kuramae ◽

Eliana Midori Tanaka ◽

Takashi Sakurai ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Mouth Opening ◽

Pharmacological Therapy ◽

Open Bite ◽

Anterior Open Bite ◽

Orthodontic Therapy ◽

Japanese Female ◽

Severe Erosion ◽

Old Japanese ◽

History Of

Abstract A 32-year-old Japanese female patient consulted the authors' dental clinic with a 4.5-year history of rheumatoid arthritis (RA). She complained of pain during mouth opening and difficulty in eating due to masticatory dysfunction caused by an anterior open bite. Imaging showed severe erosion and flattening of both condyles. RA stabilized after pharmacological therapy and became inactive during the orthodontic therapy aimed at reconstructing an optimal occlusion capable of promoting functional repositioning of the mandible. At present, 4 years and 2 months postretention, the reconstructed occlusion remains stable, and both condyles continue to be remodeled. The distance from reference position to intercuspal position has gradually decreased throughout the 4-year posttreatment and postretention periods. Orthodontic therapy that comprehensively reconstructs occlusion and enhances the functioning of the mandible can induce remodeling of eroded condyles, even those with a history of rheumatoid arthritis.

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