scholarly journals Phytochemical screening, antioxidant and cytotoxic activity of fruit extracts of Calamus tenuis Roxb

2014 ◽  
Keyword(s):  
Cytotoxic Activity ◽  
Phytochemical Screening ◽  
Fruit Extracts

scholarly journals Phytochemical Screening and Biocidal Studies Of Stem Bark Chrysophyllum Albidum (Linn) And Straw Aristolochia Ringens from Nigeria.

2017 ◽  
Vol 4 (1) ◽  
Author(s):  
Moses Owolabi
Keyword(s):  
Medicinal Plants ◽  
Cytotoxic Activity ◽  
Biological Activities ◽  
Stem Bark ◽  
Breast Tumour ◽  
Tumour Cells ◽  
Bacterial Activity ◽  
Liver Tumour ◽  
Phytochemical Screening ◽  
Health Maintenance

Introduction: Medicinal plants play a significant role in the health maintenance in underdeveloped countries, herbs and spices continue serve as a new sources for herbal medicines. Aim: The objective was to investigate phytochemical screening and biocidal activity on stem bark Chrysophyllum albidum (Linn) and straw Aristolochia ringens using chloroform. Methods: Chloroform extracts of C. albidum and A. ringens were obtained and screened for phytochemical constituents. The colour intensity or the precipitate formation was used as analytical responses to these tests. The Antimicrobial activities crude extracts were evaluated against some microorganisms with broth microdilution test. The extracts were screened for in-vitro cytotoxic activity against breast tumour and liver tumour cells. Results: The results of the phytochemical screening revealed the presence of alkaloids, saponins, steroids, anthraquinone and glycosides. C. albidum and A. ringens chloroform extracts revealed high quantities of alkaloid and flavonoid respectively. While cardiac glycoside and anthraquinone were found with low quantity in C. albidum and A. ringens extracts respectively. C. albidum showed promising bacterial activity against Escherichia coli and cytotoxic activity to liver tumour cells. While A. ringens, showed excellent bacterial activity against Bacillus cereus and good fungal activity against Candida albicans. A. ringens also showed cytotoxic to liver tumour and breast tumour cells. The observed antimicrobial and cytotoxic effects may be due to the antagonist or synergistic effect of the secondary metabolites identified in the extracts. Conclusion: Medicinal plants studied showed good potential biological activities that support the idea that traditional medicines remain useful healthcare in developing countries

Phytochemical screening, total phenolic content, antioxidant, and cytotoxic activity of five peruvian plants on human tumor cell lines

2018 ◽  
Vol 10 (2) ◽  
pp. 161 ◽  
Author(s):  
Oscar Herrera-Calderon ◽  
Corina Alvarado-Puray ◽  
JorgeLuis Arroyo-Acevedo ◽  
JuanPedro Rojas-Armas ◽  
Victor Chumpitaz-Cerrate ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cytotoxic Activity ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Human Tumor ◽  
Total Phenolic ◽  
Tumor Cell Lines ◽  
Phytochemical Screening ◽  
Human Tumor Cell ◽  
Human Tumor Cell Lines

scholarly journals In vitro thrombolytic, anthelmintic, anti-oxidant and cytotoxic activity with phytochemical screening of methanolic extract of Xanthium indicum leaves

2015 ◽  
Vol 10 (4) ◽  
pp. 854 ◽  
Author(s):  
Antara Ghosh ◽  
Sujan Banik ◽  
Md. Ariful Islam
Keyword(s):  
Cytotoxic Activity ◽  
Methanolic Extract ◽  
Radical Scavenging ◽  
Anthelmintic Activity ◽  
Positive Control ◽  
Clot Lysis ◽  
Total Phenolic ◽  
Phytochemical Screening ◽  
Anti Oxidant

<p class="Abstract"><em>Xanthium indicum</em> is an important medicinal plant traditionally used in Bangladesh as a folkloric treatment. The current study was undertaken to evaluate thrombolytic, anthelmintic, anti-oxidant, cytotoxic properties with phytochemical screening of methanolic extract of <em>X. indicum</em> leaves. The analysis of phytochemical screening confirmed the existence of phytosetrols and diterpenes. In thrombolytic assay, a significant clot lysis was observed at four concentrations of plant extract compare to the positive control streptokinase (30,000 IU, 15,000 IU) and negative control normal saline. The extract revealed potent anthelmintic activity at different concentrations. In anti-oxidant activity evaluation by two potential experiments namely total phenolic content determination and free radical scavenging assay by 2, 2-diphenylpicrylhydrazyl (DPPH), the leaves extract possess good anti-oxidant property. In the brine shrimp lethality bioassay, the crude extract showed potent (LC<sub>50</sub> 1.3 μg/mL) cytotoxic activity compare to the vincristine sulfate as a positive control (LC<sub>50</sub> 0.8 μg/mL). </p><p> </p>

Phytochemical screening and evaluation of cytotoxic activity of Calotropis gigantea leaf extract on MCF7, HeLa, and A549 cancer cell lines

2019 ◽  
Vol 10 (2) ◽  
pp. 131 ◽  
Author(s):  
Venkataraman Prabhu ◽  
Bindu Damodaran ◽  
Prashantha Nagaraja ◽  
Vivek Jain ◽  
MP Manuja Viraj Wimalasiri ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Leaf Extract ◽  
Cancer Cell Lines ◽  
Phytochemical Screening ◽  
Calotropis Gigantea

scholarly journals Antimicrobial, Antioxidant and Cytotoxic Activities and Phytochemical Screening of Some Yemeni Medicinal Plants

2010 ◽  
Vol 7 (3) ◽  
pp. 323-330 ◽  
Author(s):  
Ramzi A. A. Mothana ◽  
Salah A. A. Abdo ◽  
Sidgi Hasson ◽  
Faisal M. N. Althawab ◽  
Sama A. Z. Alaghbari ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Cytotoxic Activity ◽  
Hot Water ◽  
Diffusion Method ◽  
Scavenging Activity ◽  
Phytochemical Screening ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Methanolic Extracts ◽  
Multiresistant Bacteria

The traditional medicine still plays an important role in the primary health care in Yemen. The current study represents the investigation of 16 selected plants, which were collected from different localities of Yemen. The plants were dried and extracted with two different solvents (methanol and hot water) to yield 34 crude extracts. The obtained extracts were tested for their antimicrobial activity against three Gram-positive bacteria, two Gram-negative bacteria, one yeast species and three multiresistantStaphylococcusstrains using agar diffusion method, for their antioxidant activity using scavenging activity of DPPH radical method and for their cytotoxic activity using the neutral red uptake assay. In addition, a phytochemical screening of the methanolic extracts was done. Antibacterial activity was shown only against Gram-positive bacteria, among them multiresistant bacteria. The highest antimicrobial activity was exhibited by the methanolic extracts ofAcalypha fruticosa,Centaurea pseudosinaica,Dodonaea viscosa,Jatropha variegata,Lippia citriodora,Plectranthus hadiensis,Tragia pungensandVerbascum bottae.Six methanolic extracts especially those ofA. fruticosa,Actiniopteris semiflabellata,D. viscosa,P. hadiensis,T. pungensandV. bottaeshowed high free radical scavenging activity. Moreover, remarkable cytotoxic activity against FL-cells was found for the methanolic extracts ofA. fruticosa,Iris albicans,L. citriodoraandT. pungens. The phytochemical screening demonstrated the presence of different types of compounds like flavonoids, terpenoids and others, which could be responsible for the obtained activities.

scholarly journals Triagem fitoquímica e avaliação das atividades antioxidante e citotóxica de extratos etanólicos de Malvaviscus arboreus Cav. (MALVACEAE)

2017 ◽  
Vol 2 (1) ◽  
pp. 9-24
Author(s):  
Jhonatan Da Cruz Ribeiro ◽  
Marco Aurélio Sivero Mayworm
Keyword(s):  
Antioxidant Activity ◽  
Cytotoxic Activity ◽  
Folk Medicine ◽  
Artemia Salina ◽  
Ethanol Solution ◽  
Cytotoxic Activities ◽  
Total Phenols ◽  
Phytochemical Screening ◽  
Root Extracts ◽  
Sedative Activity

Resumo: Malvaviscus arboreus pertencente à família Malvaceae, é utilizada em jardinagem, medicina popular e na culinária. Estudos anteriores demonstraram atividade moluscicida e alelopática de extrato das raízes; e atividade antitussígena, emoliente e sedativa de extrato das fl ores. Este trabalho visou avaliar as atividades antioxidante e citotóxica, e realizar triagem fi toquímica de extratos etanólicos produzidos a partir de segmentos de caule, folhas e fl ores de M. arboreus. A triagem fi toquímica avaliou a presença de fenóis totais, fl avonoides, quinonas, saponinas, alcaloides e antocianinas. A atividade antioxidante foi avaliada utilizando-se solução etanólica de DPPH (2,2-difenil-1-picrilidrazila) e os valores de absorbância foram interpretados em percentuais de atividade antioxidante (AA%). A atividade citotóxica foi avaliada através do teste de letalidade contra Artemia salina Leach. Demonstrou-seque todos os extratos apresentaram fenóis totais e fl avonoides, porém somente o extrato de fl ores apresentou antocianinas. Quanto à atividade antioxidante, o extrato etanólico de folhas mostrou-se o mais ativo nas concentrações de 100 μg/mL, 50 μg/mL e 10 μg/mL, comparado aos demais extratos. Na avaliação citotóxica, o extrato de fl ores demonstrou maior toxicidade sobre Artemia nas duas concentrações testadas (1mg/mL e 0,5 mg/mL). Conclui-se que os extratos de caule, folhas e fl ores de Malvaviscus arboreus têm potenciais antioxidante e citotóxico nas concentrações testadas.Palavras-chaves: Malvaviscus arboreus; Triagem fi toquímica; Atividade antioxidante; Atividade citotóxica.Abstract: Malvaviscus arboreus (family Malvaceae), is used in gardening, folk medicine and in cooking. Previous studies have shown molluscicidal and allelopathic activity of the root extracts, antitussive, emollient and sedative activity from extracts of fl owers. Th is study evaluated the antioxidant and cytotoxic activities and performing phytochemical screening in ethanolic extracts from segments of stem, leaves and fl owers of M. arboreus. Th e phytochemical screening aimed to evaluate the presence of total phenols, fl avonoids, quinones, saponins, alkaloids and anthocyanins. Th e antioxidant activity was evaluated using ethanol solution of DPPH (2,2-diphenyl-1-picrylhydrazyl) and absorbance values were interpreted as a percentage of antioxidant activity (AA%). Th e cytotoxic activity of the extracts was assessed using the lethality test against Artemia salina Leach. Was shown that all extracts showed total phenols and fl avonoids, but only the fl ower extract showed anthocyanins. As the antioxidant activity, the leaves extract was found to be the most active in the concentrations of 100 μg/mL, 50 μg/mL and 10 μg/mL, when compared with other extracts. In the cytotoxic evaluation , the fl ower extract showed greater toxicity on Artemia in the two concentrations tested (1mg/mL and 0,5 mg/mL). It’s concluded that the extracts of stem, leaves and fl owers of Malvaviscus arboreus have antioxidant and cytotoxic potential, at the concentrations tested.Key-words: Malvaviscus arboreus; Phytochemical screening; Antioxidant activity; Cytotoxic activity.

scholarly journals Antioxident activities and Phytochemical Screening of Martynia Annua Fruit Extract

2017 ◽  
Vol 14 (4) ◽  
pp. 1363-1369
Author(s):  
Zarina Arshad ◽  
Sumayya Saied ◽  
Khalid M.Khan ◽  
Shaista Naz
Keyword(s):  
Lipid Peroxidation ◽  
Reducing Power ◽  
Phytochemical Analysis ◽  
Skin Infections ◽  
Inhibition Assay ◽  
Phytochemical Screening ◽  
Fruit Extract ◽  
Fruit Extracts ◽  
Reducing Power Assay ◽  
Lipid Peroxidation Inhibition

ABSTRACT: Martynia annua (cat’s claw, bichu) is part of Martyniaceae family. For centuries, extracts of leaves, roots, stems, fruits and seeds of M. annua have been used to cure eplilepsy, inflammation, tuberculosis, skin infections etc. Present investigations revealed qualitative phytochemical screening and bioactivites of fruit extracts of M.annua in solvents of different polarties. The qualitative phytochemical analysis exhibited the presence of alkaoids, flavonoids, glycosides, saponins, tannis, anthocyanins, steroids, amino acids and phenols. DPPH (1.1-diphenyl-2-dipicryl hydrzal free radical scanvenging, reducing power assay and lipid peroxidation inhibition assay likability in different solvents were explored which revealed that with increase in concentration of extracts resulted increase in degree of reduction. The outcome of the present studies revealed that the fruit extracts of M. annua have eminent antioxidant activity

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