Age, alcohol, sex, and metabolic factors as risk factors for colonic diverticulosis

Background: Metabolic factors have been linked to tendinopathies, yet few studies have investigated the association between metabolic factors and lateral epicondylitis. Purpose: To evaluate risk factors for lateral epicondylitis, including several metabolic factors. Study Design: Case-control study; Level of evidence, 3. Methods: We evaluated 1 elbow in each of 937 volunteers from a rural region that employs many agricultural laborers. Each participant received a questionnaire, physical examinations, blood tests, simple radiographic evaluations of both elbows, magnetic resonance imaging of bilateral shoulders, and an electrophysiological study of bilateral upper extremities. Lateral epicondylitis was diagnosed using 3 criteria: (1) pain at the lateral aspect of the elbow, (2) point tenderness over the lateral epicondyle, and (3) pain during resistive wrist dorsiflexion with the elbow in full extension. Multivariable logistic regression analysis was used to calculate the odds ratios (ORs) and 95% CIs for various demographic, physical, and social factors, including age, sex, waist circumference, dominant-side involvement, smoking habit, alcohol intake, and participation in manual labor; the comorbidities of diabetes, hypertension, thyroid dysfunction, metabolic syndrome, ipsilateral biceps tendon injury, ipsilateral rotator cuff tear, and ipsilateral carpal tunnel syndrome; and the serologic parameters of serum lipid profile, glycosylated hemoglobin A1c, level of thyroid hormone, and high-sensitivity C-reactive protein. Results: The prevalence of lateral epicondylitis was 26.1% (245/937 participants). According to the multivariable logistic regression analysis, female sex (OR, 2.47; 95% CI, 1.78-3.43), dominant-side involvement (OR, 3.21; 95% CI, 2.24-4.60), manual labor (OR, 2.25; 95% CI, 1.48-3.43), and ipsilateral rotator cuff tear (OR, 2.77; 95% CI, 1.96-3.91) were significantly associated with lateral epicondylitis ( P < .001 for all). No metabolic factors were significantly associated with lateral epicondylitis. Conclusion: Female sex, dominant-side involvement, manual labor, and ipsilateral rotator cuff tear were found to be risk factors for lateral epicondylitis. The study results suggest that overuse activity is more strongly associated with lateral epicondylitis than are metabolic factors.

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P.02.25 RISK FACTORS FOR COLONIC DIVERTICULOSIS: A STUDY IN PRIMARY CARE SETTING

Digestive and Liver Disease ◽

10.1016/s1590-8658(19)30310-x ◽

2019 ◽

Vol 51 ◽

pp. e158

Author(s):

A. Violi ◽

G. Cambiè ◽

M. Franceschi ◽

G. Baldassarre ◽

K.I. Rodriguez-Castro ◽

...

Keyword(s):

Risk Factors ◽

Primary Care ◽

Care Setting ◽

Primary Care Setting ◽

Colonic Diverticulosis

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Tu1179 Clinical Characteristics and Risk Factors of Colonic Diverticulosis - Analysis From Japanese Multicenter Prospective Cross-Sectional Study-

Gastroenterology ◽

10.1016/s0016-5085(13)62895-4 ◽

2013 ◽

Vol 144 (5) ◽

pp. S-782

Author(s):

Yasuhiko Maruyama ◽

Masami Yamada ◽

Noriaki Manabe ◽

Atsushi Nakajima ◽

Motowo Mizuno ◽

...

Keyword(s):

Risk Factors ◽

Clinical Characteristics ◽

Cross Sectional Study ◽

Sectional Study ◽

Colonic Diverticulosis ◽

Cross Sectional

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Rhino-orbito-cerebral Mucormycosis: Pictorial Review

Insights into Imaging ◽

10.1186/s13244-021-01109-z ◽

2021 ◽

Vol 12 (1) ◽

Author(s):

Vivek Pai ◽

Rima Sansi ◽

Ritesh Kharche ◽

Sridevi Chaitanya Bandili ◽

Bhujang Pai

Keyword(s):

Risk Factors ◽

Elevated Serum ◽

Metabolic Factors ◽

Clinical Form ◽

Complex Interplay ◽

Cross Sectional ◽

Pictorial Review ◽

Adjacent Structures ◽

Pictorial Essay ◽

Cross Sectional Imaging

AbstractMucormycosis (MCR) is a fulminant, potentially lethal, opportunistic fungal infection. Diabetes, immunocompromised states and elevated serum iron levels are the most important risk factors for contracting MCR infection. Recently, MCR co-infections have been observed in patients with COVID-19 disease owing to a complex interplay of metabolic factors and corticosteroid therapy. Rhino-orbito-cerebral mucormycosis (ROCM) is the most common clinical form of MCR infection and refers to infection of the nasal cavities, paranasal sinuses, neck spaces, orbits and intracranial structures. Sinonasal inoculation is typically the primary site of infection; the necrotising and angioinvasive properties of the fungus facilitate its spread into adjacent structures. In this review, we discuss the pertinent mycology and risk factors of MCR infection. The review also aims to acquaint the reader with the cross-sectional imaging appearances of ROCM and its complications. All the cases discussed in this pictorial essay are microbiologically and/or histopathologically proven cases of ROCM with concomitant COVID-19 infection.

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Risk Factors for Shoulder Stiffness: Current Concepts

Joints ◽

10.1055/s-0037-1608951 ◽

2017 ◽

Vol 05 (04) ◽

pp. 217-223 ◽

Cited By ~ 10

Author(s):

Davide Cucchi ◽

Antongiulio Marmotti ◽

Silvana De Giorgi ◽

Alberto Costa ◽

Rocco D'Apolito ◽

...

Keyword(s):

Risk Factors ◽

Molecular Biology ◽

Range Of Motion ◽

Metabolic Factors ◽

Postoperative Rehabilitation ◽

Shoulder Stiffness ◽

Medical Disorders ◽

Rehabilitation Protocols ◽

Postoperative Shoulder

AbstractShoulder stiffness is a condition of painful restriction of the glenohumeral range of motion. Numerous risk factors for primary and postoperative shoulder stiffness have been described. This article summarizes the known aspects of the pathophysiology of shoulder stiffness, with special attention to elements of molecular biology and genetics, which could influence the risk of developing shoulder stiffness. Furthermore, the role of hormonal and metabolic factors, medical disorders, drugs, and of other published risk factors for primary and postoperative shoulder stiffness is reviewed and discussed. Finally, aspects related to shoulder surgery and postoperative rehabilitation protocols, which could influence the development of postoperative stiffness are presented.

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Environmental and Dietary Risk Factors for Colonic Diverticulosis and Diverticulitis

Journal of Gastrointestinal and Liver Diseases ◽

10.15403/jgld-3208 ◽

2021 ◽

Vol 30 (1) ◽

pp. 66-72

Author(s):

Jaune Ieva Lukosiene ◽

Matthias Christian Reichert ◽

Frank Lammert ◽

Christoph Schramm ◽

Tobias Goeser ◽

...

Keyword(s):

Risk Factors ◽

Educational Status ◽

Cross Sectional Study ◽

Older Age ◽

Colonic Diverticulosis ◽

Full Data ◽

Cross Sectional ◽

Education Group ◽

Increased Risk ◽

Bowel Movements

Background and Aims: Colonic diverticulosis (CD) is among the most common conditions of the large bowel. Several factors have been associated with an increased risk of CD and its complications, including advanced age, obesity, physical inactivity, and a low-fiber diet. Available data is conflicting and a comprehensive analysis of different bowel, dietary and environmental habits linked with CD is lacking. We aimed to investigate the relationship between potential risk factors and CD prevalence using full data from a colonoscopy-based cross-sectional study in Europe. Methods: The study was conducted at three tertiary referral centers in Germany and Lithuania. It included consecutive adult patients referred for routine colonoscopy who completed a detailed questionnaire on our considered multiple risk factors for diverticulosis and diverticulitis, including dietary and environmental factors, and bowel habits. Results: The study included 1,333 patients, 696 women and 635 men. Colonic diverticulosis was diagnosed in 858 (64%) of patients. Multivariate analysis revealed that age (OR: 1.08, 95%CI: 1.06–1.10, p<0.001) and obesity (OR: 1.05, 95%CI: 1.02–1.09, p=0.004) were associated with CD. We also revealed new risk factors for CD: increased frequency of bowel movements (OR: 0.10, 95%CI: 0.03-0.33, p<0.001) and feeling of incomplete bowel emptying (OR: 2.05, 95%CI: 1.47–2.87, p<0.001). Older participants had reduced odds (OR: 0.921, 95 CI: 0.89–0.95, p<0.05) of diverticulitis compared to younger subjects. Feeling of incomplete bowel emptying after defecation was associated with increased odds (OR: 2.769, 95% CI 1.35–5.7, p<0.006) for diverticulitis. Moreover, participants with a higher educational status had increased odds (OR: 2.453, 95%CI: 1.31–4.59, p=0.005) for diverticulitis compared to the lower education group. Conclusions: Study shows that older age, obesity, frequency of bowel movements, and feeling of incomplete bowel emptying are associated with the risk of CD. Furthermore, older age, feeling of incomplete bowel emptying, and higher education were associated with the risk of diverticulitis among CD patients.

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Prevalence and Associated Metabolic Factors for Thyroid Nodules: A Cross-Sectional Study in Southwest of China with More Than 120 Thousand Populations

10.21203/rs.3.rs-436890/v1 ◽

2021 ◽

Author(s):

Li Xu ◽

Fanling Zeng ◽

Yutong Wang ◽

Ye Bai ◽

Xuefeng Shan ◽

...

Keyword(s):

Risk Factors ◽

Central Obesity ◽

Thyroid Nodules ◽

Health Management ◽

Female Gender ◽

Cross Sectional Study ◽

Advanced Age ◽

Metabolic Factors ◽

Cross Sectional ◽

Independent Risk Factors

Abstract Objective. To explore the prevalence and its associated metabolic factors of thyroid nodules (TNs) among subjects who participated in the physical examinations in Chongqing, China. Methods. The participants from the Health Management Center of JinShan Hospital of Chongqing Medical University, between September 2015 and May 2020, were included in this study. All of the participants underwent thyroid ultrasonography, anthropometric measurements, and serum examinations. Differences in the TNs prevalence were compared with the chi-square test or Wilcoxon rang-sum test. Multivariable logistic regression analyses were used to estimate the metabolic factors associated with TNs and multi thyroid nodules (MTNs). Results. Of the included 121702 participants, 41547 had TNs, and 20899 had MTNs, with the prevalence of 34.1% and 17.0%, respectively. Women had a significantly higher prevalence of TNs than men (40.6% vs. 29.8%; χ2 = 1517.33, P < 0.001), and TNs prevalence was gradually increased with age (P for trend < 0.001). Female gender, advanced age, and metabolic factors including central obesity, BMI,hypertension, diabetes and fatty liver were positively associated with TNs; hyperlipoidemia and hyperuricemia were not independent risk factors of TNs. While female gender, advanced age, central obesity, hypertension and diabetes were independent risk factors of MTNs. Conclusions. The prevalence of thyroid nodules was relatively high. The associated factors identified in this study could help the clinicians to detect the high-risk patients and make targeted screening strategies for the preventing of the occurrence of TNs.

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S186 Risk Factors for Location of Colonic Diverticulosis in an Aging Population—A Retrospective Study

The American Journal of Gastroenterology ◽

10.14309/01.ajg.0000773216.10137.55 ◽

2021 ◽

Vol 116 (1) ◽

pp. S83-S84

Author(s):

Hammad Liaquat ◽

Hussam Tayel ◽

Farah Harmouch ◽

Brian Kim ◽

Berhanu Geme ◽

...

Keyword(s):

Risk Factors ◽

Retrospective Study ◽

Aging Population ◽

Colonic Diverticulosis

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The Association of Healthy Behaviors and Metabolic Factors With Dyslipidemia Among Miao Adults: The China Multi-Ethnic Cohort (CMEC) Study

10.21203/rs.3.rs-110397/v1 ◽

2020 ◽

Author(s):

Fang Nie ◽

Ziyun Wang ◽

Qibing Zeng ◽

Han Guan ◽

Jingyuan Yang ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Fasting Blood Glucose ◽

Binary Logistic Regression ◽

Baseline Survey ◽

Metabolic Factors ◽

Binary Logistic Regression Model ◽

Healthy Behaviors ◽

Almost All ◽

Representative Samples

Abstract Background: Behavioral and metabolic risk factors will increase the risk of dyslipidemia, the association of behaviors and metabolic factors with dyslipidemia among Miao adults are still unclear. Objective: To evaluate the association between behaviors, metabolic factors and dyslipidemia.Methods: Based on the CMEC study, a representative samples of 5,559 Miao participants aged 30 to 79 years old who were included in the baseline survey from 2018 to 2019 were analyzed. A binary logistic regression model was utilized to evaluate the odds ratios (OR) and 95% confidence intervals (CI) of the associations of healthy behaviors and metabolic factors with dyslipidemia.Results: In both sexes, only a small percentage of females with ideal levels of waist-to-hip ratio (WHR) (27.2%). However, participants were more likely to have ideal levels of fasting blood glucose (FBG). In addition, males with dyslipidemia had poor levels of body mass index (BMI) (60.3%), WHR (59.2%) and FBG (65.8%). While females with dyslipidemia had poor levels of FBG (60.0%). Notably, our study found that WHR, BMI, FBG, and blood pressure were major risk factors for almost all dyslipidemia components. Conclusions: The rate of dyslipidemia cannot be ignored, particularly high TG levels. In addition, healthy behaviors and metabolic factors, especially WHR, BMI, FBG levels, and blood pressure were significantly associated with dyslipidemia, which may have become a major challenge to public health problems in the ethnic minority areas of Guizhou.

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Effects of Metabolic Factors, Race-Ethnicity, and Sex on the Development of Nephropathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study

10.2337/figshare.15144999 ◽

2021 ◽

Author(s):

Petter Bjornstad ◽

Laure El ghormli ◽

Kara S. Hughan ◽

Lori M. Laffel ◽

Kristen J. Nadeau ◽

...

Keyword(s):

Risk Factors ◽

Type 2 Diabetes ◽

Young Adults ◽

Uric Acid ◽

Serum Uric Acid ◽

Adolescents And Young Adults ◽

Metabolic Factors ◽

Β Cell ◽

Race Ethnicity

Objective: To describe the longitudinal effects of sex, race-ethnicity, and metabolic factors on the risk of developing diabetic kidney disease (DKD) in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) cohort. ResearchDesignandMethods: Urine albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) by serum creatinine and cystatin C were assessed annually for up to 15 years after study entry. Markers of DKD included micro- and macroalbuminuria (UACR ≥30 mg/g and ≥300 mg/g, respectively), hyperfiltration (eGFR ≥135 ml/min/1.73m2), and rapid eGFR annual decline (>3 ml/min/1.73m2, and/or ≥3.3%). The relationships between risk factors and DKD were evaluated longitudinally using time-to-event models. Results: Data were available on 677 participants, average age at baseline 14 years, with a mean follow-up of 10.2 ± 4.5 years. Each 1% increment in HbA1c conferred higher risk of microalbuminuria (HR: 1.24, 95% CI [1.18, 1.30]), macroalbuminuria (1.22, [1.11, 1.34]), hyperfiltration (1.11, [1.05, 1.17]), and rapid eGFR decline (1.12, [1.04, 1.20]). Higher SBP and baseline serum uric acid, and lower indices of β-cell function (C-peptide index and oral disposition index [oDI]), increased the risk of microalbuminuria, while higher triglycerides increased risk of micro- and macroalbuminuria. Lower oDI levels, female sex, and Hispanic ethnicity were associated with higher risk of hyperfiltration. Conclusions: Elevated HbA1c was a shared risk factor among all phenotypes of DKD in this longitudinal cohort of adolescents and young adults with youth-onset type 2 diabetes. Other risk factors included elevated blood pressure, triglycerides, serum uric acid and β-cell dysfunction.

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