Sucrose Analgesia for Minor Procedures in Newborn Infants

2001 ◽  
Vol 35 (7-8) ◽  
pp. 947-952 ◽  
Author(s):  
Lory D Masters-Harte ◽  
Susan M Abdel-Rahman
Keyword(s):  
Sucrose Solution ◽  
Newborn Infants ◽  
Pain Scale ◽  
Pain Response ◽  
Extensive Review ◽  
Invasive Procedures ◽  
Data Synthesis ◽  
Lower Pain ◽  
Effective Analgesia

OBJECTIVE: T o evaluate the role of intraoral sucrose and other sweet-tasting solutions for the management of pain associated with minor procedures in newborns. DATA SOURCES: A search of MEDLINE articles from 1966 to August 1999 and an extensive review of journals was conducted. MeSH headings included analgesia, sucrose, and neonate. DATA SYNTHESIS: Newborn infants regularly undergo minor invasive procedures for which analgesics are not routinely used. Intraoral sucrose and other sweet-tasting solutions appear to diminish surrogate biomarkers of pain response as evidenced by a reduction in crying time, smaller increases in heart rate, and lower pain scale ratings. CONCLUSIONS: These studies appear to suggest that sucrose solution 0.5 g provides effective analgesia with no reported adverse effects.

scholarly journals Analgesia in newborns: a case-control study of the efficacy of nutritive and non-nutritive sucking stimuli

CoDAS ◽  
2013 ◽  
Vol 25 (4) ◽  
pp. 365-368 ◽  
Author(s):  
Ana Henriques Lima ◽  
Ana Paula Hermont ◽  
Amélia Augusta de Lima Friche
Keyword(s):  
Case Control Study ◽  
Pain Scale ◽  
Case Control ◽  
Control Group ◽  
Pain Response ◽  
The Third ◽  
Nutritive Sucking ◽  
Lower Pain ◽  
Infant Pain ◽  
Control Study

PURPOSE: To verify the nutritive and non-nutritive stimuli efficacy in the newborn's response to pain during venipuncture. METHODS: The main sample was composed of 64 newborns that were randomly divided into three groups. The first group (n=20) received nutritive sucking stimulus that was performed through maternal breastfeeding. The second group (n=21) received non-nutritive sucking stimulus that was performed through the introduction of the researcher little finger in the newborn's oral cavity. The third group or control group (n=23) did not receive any analgesia stimulus. The newborns were evaluated using the Neonatal Infant Pain Scale, and the responses to painful stimuli were compared. RESULTS: The nutritive as well as non-nutritive suction methods provided a comforting effect, resulting in lower pain response scores (p<0.05). There was no difference between the analgesia provided by both methods (p>0.05). CONCLUSION: The nutritive and the non-nutritive sucking stimuli proved to be efficacious tools in relieving pain among newborns.

scholarly journals Pengaruh Metode 5’S (Swadding, Stomach Position, Sushing, Swingging, Sucking) terhadap Respon Nyeri Bayi Setelah Imunisasi HB-0

2020 ◽  
Vol 5 (2) ◽  
pp. 141
Author(s):  
Syatriawati Syatriawati ◽  
Iskandar Markus Sembiring
Keyword(s):  
Acute Pain ◽  
Sampling Technique ◽  
Pain Scale ◽  
Test Design ◽  
Pain Response ◽  
Inclusion Criteria ◽  
Paired Sample ◽  
Post Test ◽  
Lower Pain ◽  
Infant Pain

Immunization is a source of acute pain in infants that can cause trauma, nonpharmacological techniques that can be done is by giving of 5'S  method(swaddling, stomach position, sushing, swinging, and sucking) which are effective and easy to do and the purpose of this study was to find out whether there is an effect of 5'Smethod (swaddling, stomach position, sushing, swinging and sucking) on pain response in infants after Hb-0 immunization at Grandmed Hospital LubukPakam, the method and design of this study was Quasy Experiment with one group pre test and post test design. the population in this study were infants aged0-7 days who received Hb-0 immunization, amounting to 40 people with purposive sampling technique according to inclusion criteria and pain measurement uses the NIPS (Neonatal Infant Pain Scale) pain scale, the data analysis was performed by Paired Sample t-test with a confidence level of 0.05%, the results of the study were lower pain in the treatment group with p = 0.0000 <0.05 (<ɑ), the conclusion of this study is that there was an effect of the 5'S method (swaddling, stomach position, sushing, swinging, and sucking) on pain response in infants after Hb-0 immunization.Immunization is a source of acute pain in infants that can cause trauma, nonpharmacological techniques that can be done is by giving of 5'S  method(swaddling, stomach position, sushing, swinging, and sucking) which are effective and easy to do and the purpose of this study was to find out whether there is an effect of 5'Smethod (swaddling, stomach position, sushing, swinging and sucking) on pain response in infants

scholarly journals Role of sucrose, pacifier and their combination as pain reliever among preterm neonates during painful procedures

2019 ◽  
Vol 9 (5) ◽  
pp. 95
Author(s):  
Youssria El-Sayed Yousef ◽  
Nora Abd-Elhamid Zaki ◽  
Amal Sayed Ali
Keyword(s):  
Clinical Data ◽  
Sucrose Solution ◽  
Newborn Infants ◽  
Preterm Neonates ◽  
Control Group ◽  
Pain Reliever ◽  
Combination Methods ◽  
Nutritive Sucking ◽  
Oral Sucrose

Background/Objective: The role of sucrose and/or non-nutritive sucking (NNS) has been evaluated for relieving procedural pain in newborn infants with satisfactory results however there was a controversy regarding the synergestic effect of their combination.}Methods: This quasi-experimental study was conducted in the neonatal intensive care unit in Assiut University Children Hospital including 120 preterm neonates who were divided into 4 groups (20 neonates each). Control group received routine hospital care; sucrose group received oral sucrose solution (OS); pacifier group received pacifier; and last group received oral sucrose solution and pacifier during painful procedures. All were assessed regarding socio-demographic and clinical data in addition to application of Premature Infant Pain Profile (PIPP) scale to assess the levels of pain and mean pain scores pre and post-intervention.Results: The 4 groups were similar regarding soci-demographic and clinical data. The application of the OS and/or pacifier, led to significant improvement of the levels of pain and reduction of the mean score of pain among preterm neonates during painful procedures. In addition, combined pacifier and OS was superior to OS alone and comparable to pacifier alone regarding their effect on the reduction of pain level and mean score of pain.Conclusions: OS and pacifier are effective as pain reliever during painful procedures among preterm neonates. Combined OS and pacifier is superior to OS and pacifier alone.

Evidence-Based Review of Oral Sucrose Administration to Decrease the Pain Response in Newborn Infants

2006 ◽  
Vol 25 (4) ◽  
pp. 275-284 ◽  
Author(s):  
Kathleen Leef
Keyword(s):  
Preterm Infants ◽  
Newborn Infants ◽  
Pain Response ◽  
Evidence Based ◽  
Invasive Procedures ◽  
Term Infants ◽  
Safety And Efficacy ◽  
Single Procedure ◽  
Repeated Doses ◽  
Oral Sucrose

Pain assessment and management are important issues for the neonatal nurse today. Clinicians have gradually come to acknowledge that newborn infants (term and preterm) are capable of responding to painful stimuli. This article reviews the evidence regarding the safety and efficacy of oral sucrose administration, to help answer the clinical question of how to manage an infant’s pain response to minor invasive procedures that are everyday occurrences in the NICU. This review included information on 1,077 infants enrolled in 16 studies. The evidence presented in the 16 studies reviewed here shows the safety and efficacy of sucrose in decreasing term infants’ pain response to a single procedure. In regard to preterm infants, there is insufficient evidence to recommend the use of sucrose as a routine comfort measure. More research is needed to determine the safety and efficacy of repeated doses of oral sucrose given for multiple procedures in preterm infants.

Pre-emptive Analgesia for Postoperative Pain Relief in Children – Role of Paracetamol

2009 ◽  
pp. 9-16
Author(s):  
Rubina Yasmin ◽  
AKM Akhtaruzzaman ◽  
Paresh Chandra Sarker ◽  
Neaz Ahmed ◽  
Ranadhir Kumar Kundu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Postoperative Pain ◽  
Diclofenac Sodium ◽  
Total Duration ◽  
Pain Scale ◽  
Prospective Clinical Study ◽  
High Dose ◽  
Induction Of Anaesthesia

This prospective clinical study was carried out in the Dept. of Anaesthesia, Analgesia and Intensive Care Medicine, BSMMU, Dhaka, during the period of May 2003 to July 2003. The study was done to emphasize the importance of giving analgesics preemptively instead of waiting for the child to complain of pain and to produce smooth recovery after surgery by decreasing immediate postoperative pain in children by a simple, safe acceptable drug. The children scheduled for tonsillectomy under general anaesthesia were recruited in this study. The analgesic efficiency of rectal paracetamol in two doses, 25 mg/kg bodywt.(Gr-P25) and 50 mg/kg. bodywt. (Gr-P50) were compared with Diclofenac Sodium suppository 1mg/ kg body weight (Gr-D) given half an hour before induction of anaesthesia. Pain scoring was done by TPPPS (Toddler Pre-schooler postoperative pain scale). Heart rate and blood pressure were stable in Gr-P50 and Gr-D. Time of first demand of analgesic was delayed in Gr-P50 and Gr-D. Total paracetamol consumption in 24 hours was less in Gr-P50(181±14.25) and Gr-D (212±25) than Gr-P25(318± 26.39). Total duration of analgesia in Gr- P50 (657±9.94) mins. and in Gr- D(502±10.63) mins. and in Gr-P25(288±23.17) mins. Pre-emptive high dose rectal paracetamol appears to be more effective than diclofenac sodium suppository for postoperative analgesia in children undergoing tonsillectomy. Journal of BSA, Vol. 18, No. 1 & 2, 2005 p.9-16

The role of TLR2 in the implementation of congenital and acquired pneumonia in newborn infants

2016 ◽  
Vol 80 (8) ◽  
pp. 26-29
Author(s):  
O.S. Yablon ◽  
◽  
I.I. Reminna ◽  
Keyword(s):  
Newborn Infants

Medic Interaction Modes and Hospitalized Children Health

2019 ◽  
Author(s):  
Naveed Shibli ◽  
Miss Shehrish Farooq
Keyword(s):  
Experimental Study ◽  
Health Outcomes ◽  
Block Design ◽  
Pain Scale ◽  
Hospitalized Children ◽  
Face Pain ◽  
Children Health ◽  
Face Pain Scale

<p></p><p>In the present experimental study different interaction ‘modes’ those took place between a psychologist and a child were tested for the role of these towards health recovery of the child? Following were the interaction modes, a) presenting a flower with smile plus inquiring about health, b) offering a blessing plus inquiring about health, c) making an indifferent presence plus inquiring about health with flat tone, d) inquiring about health with providing precautions about prognosis. It was assumed that all modes would differently influence health outcomes? 100 hospitalized children located in child wards of different hospitals with randomized pre-post block design interacted. One each from four interaction modes was used for a group of 25 participants each. Actual ward discharge was compared with anticipatory estimated by each ward in-charge to calculate effect of mode on outcome. Face Pain Scale, The Children Happiness Scale and a Demographic Sheet were also used. Results reflected ‘modes’ relationship with outcomes. More studies would clarify further.</p><br><p></p>

Chemo- and Optogenetic Strategies for the Elucidation of Pain Pathways

2019 ◽  
pp. 816-832 ◽  
Author(s):  
Sascha R. A. Alles ◽  
Anne-Marie Malfait ◽  
Richard J. Miller
Keyword(s):  
Chronic Pain ◽  
Pain Response ◽  
Conscious Perception ◽  
Novel Therapies ◽  
The Past ◽  
Nociceptive Pathways ◽  
Pain Pathways ◽  
Technical Advances ◽  
The Brain

Pain is not a simple phenomenon and, beyond its conscious perception, involves circuitry that allows the brain to provide an affective context for nociception, which can influence mood and memory. In the past decade, neurobiological techniques have been developed that allow investigators to elucidate the importance of particular groups of neurons in different aspects of the pain response, something that may have important translational implications for the development of novel therapies. Chemo- and optogenetics represent two of the most important technical advances of recent times for gaining understanding of physiological circuitry underlying complex behaviors. The use of these techniques for teasing out the role of neurons and glia in nociceptive pathways is a rapidly growing area of research. The major findings of studies focused on understanding circuitry involved in different aspects of nociception and pain are highlighted in this article. In addition, attention is drawn to the possibility of modification of chemo- and optogenetic techniques for use as potential therapies for treatment of chronic pain disorders in human patients.

Open Treatment of Osteochondral Lesions of the Talus With Bone Grafting and Particulated Juvenile Cartilage Allografting

2021 ◽  
pp. 193864002110097
Author(s):  
Suhas P. Dasari ◽  
Thomas M. Langer ◽  
Derek Parshall ◽  
Brian Law
Keyword(s):  
Therapeutic Option ◽  
Symptomatic Improvement ◽  
Pain Scale ◽  
Osteochondral Lesions ◽  
Outcome Scores ◽  
Scale Scores ◽  
Open Treatment ◽  
Bone Autograft

Background: Large cystic osteochondral lesions of the talus (OLT) are challenging pathological conditions to treat, but particulated juvenile cartilage allografts (PJCAs) supplemented with bone grafts are a promising therapeutic option. The purpose of this project was to further elucidate the role of PJCA with concomitant bone autografts for treating large cystic OLTs with extensive subchondral bone involvement (greater than 150 mm2 in area and/or deeper than 5 mm). Methods: We identified 6 patients with a mean OLT area of 307.2 ± 252.4 mm2 and a mean lesion depth of 10.85 ± 6.10 mm who underwent DeNovo PJCA with bone autografting between 2013 and 2017. Postoperative outcomes were assessed with radiographs, Foot and Ankle Outcome Scores (FAOS), and visual pain scale scores. Results: At final follow-up (27.0 ± 12.59 weeks), all patients had symptomatic improvement and incorporation of the graft on radiographs. At an average of 62 ± 20.88 months postoperatively, no patients required a revision surgery. All patients contacted by phone in 2018 and 2020 reported they would do the procedure again in retrospect and reported an improvement in their symptoms relative to their preoperative state, especially with pain and in the FAOS activities of daily living subsection (91.93 ± 9.04 in 2018, 74.63 ± 26.86 in 2020). Conclusion: PJCA with concomitant bone autograft is a viable treatment option for patients with large cystic OLTs. Levels of Evidence: Level IV

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